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The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects the genetic information of animal germ cells from the deleterious effects of molecular parasites, such as transposons. Discovered nearly a...

PIWI proteins piRNA biogenesis ping-pong amplification loop post-transcriptional gene silencing (PTGS) transcriptional gene silencing (TGS) transposon control Animals Argonaute Proteins Chromosomal Proteins Non-Histone Drosophila Proteins Drosophila melanogaster Gene Silencing Histones Humans Microtubule-Associated Proteins RNA Messenger RNA Small Interfering RNA-Binding Proteins Transcription Genetic