Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response
Motaz M. Fadul,
Paul R. Heath,
Johnathan Cooper-Knock,
Julian M. Kurz,
Hayder A. Al-Azzawi,
Zarki Ali,
Taylor Smith,
Fiona E. Matthews,
Carol Brayne,
Stephen B. Wharton,
Julie E. Simpson
Oct 25, 2020
White matter lesions (WML) are a common feature of the ageing brain associated with cognitive impairment. The gene expression profiles of periventricular lesions (PVL, n = 7) and radiologically-normal-appearing (control)...