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CCR2 of Tumor Microenvironmental Cells Is a Relevant Modulator of Glioma Biology.
Matthäus Felsenstein, Anne Blank, Alexander D Bungert, Annett Mueller, Adnan Ghori, Irina Kremenetskaia, Olga Rung, Thomas Broggini, Kati Turkowski, Lea Scherschinski, Jonas Raggatz, Peter Vajkoczy, Susan Brandenburg
Jul 14, 2020
Glioblastoma multiforme (GBM) shows a high influx of tumor-associated macrophages (TAMs). The CCR2/CCL2 pathway is considered a relevant signal for the recruitment of TAMs and has been suggested as a therapeutic target in...