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HIF isoforms in the skin differentially regulate systemic arterial pressure.
Andrew S Cowburn, Norihiko Takeda, Adam T Boutin, Jung-Whan Kim, Jane C Sterling, Manando Nakasaki, Mark Southwood, Ananda W Goldrath, Colin Jamora, Victor Nizet, Edwin R Chilvers, Randall S Johnson
Jun 19, 2018
Vascular flow through tissues is regulated via a number of homeostatic mechanisms. Localized control of tissue blood flow, or autoregulation, is a key factor in regulating tissue perfusion and oxygenation. We show here that the...
HIF-alpha Arginase vascular tone Adult Aged Animals Arginase Arterial Pressure Basic Helix-Loop-Helix Transcription Factors Blotting Western Female Humans Hypertension Hypoxia-Inducible Factor 1 alpha Subunit Immunohistochemistry Keratinocytes Male Mice Mice Inbred C57BL Mice Knockout Middle Aged Nitric Oxide Synthase Type II Nitric Oxide Synthase Type III Regional Blood Flow Reverse Transcriptase Polymerase Chain Reaction Skin Young Adult
The role of epoxyeicosatrienoic acids in the cardiovascular system.