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Myelination allows for the regulation of conduction velocity, affecting the precise timing of neuronal inputs important for the development and function of brain circuits. In turn, myelination may be altered by changes in...

Xenopus adaptive myelination development experience-dependent plasticity neuron-glia interactions third harmonic generation microscopy visual system Animals Larva Myelin Basic Protein Myelin Sheath Retina Retinal Ganglion Cells Tectum Mesencephali Visual Pathways Xenopus Proteins Xenopus laevis

RNA-binding protein axon sorting topography visual system Animals Axons Embryo Nonmammalian Gene Knockdown Techniques Growth Cones Neuropilin-1 Protein Processing Post-Translational RNA-Binding Proteins Retinal Ganglion Cells Semaphorin-3A Superior Colliculi Visual Pathways Xenopus Proteins Xenopus laevis Zebrafish

H.K. Hartline. The Neural Mechanisms of Vision Lecture delivered October 30, 1941 Posted with permission

optic nerve fibers Limulus visual system

Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of KCNJ10, which encodes the inward-rectifying potassium channel KIR4.1, causes...

Kir4.1 (KCNJ10) MOUSE Neurobiology neurodegeneration neuroscience Oligodendrocytes visual system white matter Animals Axons Humans leukoencephalopathies Mice Mice Knockout Neuroglia Neurons Oligodendroglia Potassium Channels Inwardly Rectifying Seizures Spinal Cord

RESEARCH ARTICLE RESEARCH ARTICLES adaptive myelination development experience‐dependent plasticity neuron‐glia interactions third harmonic generation microscopy visual system Xenopus