Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.
Tanya M Teslovich,
Daniel Seung Kim,
Xianyong Yin,
Alena Stancáková,
Anne U Jackson,
Matthias Wielscher,
Adam Naj,
John RB Perry,
Jeroen R Huyghe,
Heather M Stringham,
James P Davis,
Chelsea K Raulerson,
Ryan P Welch,
Christian Fuchsberger,
Adam E Locke,
Xueling Sim,
Peter S Chines,
Narisu Narisu,
Antti J Kangas,
Pasi Soininen,
The Alzheimer's Disease Genetics Consortium (ADGC), The DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Genetics of Obesity-Related Liver Disease Consortium (GOLD),
Mika Ala-Korpela,
Vilmundur Gudnason,
Solomon K Musani,
Marjo-Riitta Jarvelin,
Gerard D Schellenberg,
Elizabeth K Speliotes,
Johanna Kuusisto,
Francis S Collins,
Michael Boehnke,
Markku Laakso,
Karen L Mohlke
Oct 01, 2018
Comprehensive metabolite profiling captures many highly heritable traits, including amino acid levels, which are potentially sensitive biomarkers for disease pathogenesis. To better understand the contribution of genetic...