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Development of a core measurement set for research in degenerative cervical myelopathy
Benjamin M Davies, Alvaro Yanez Touzet, Oliver D Mowforth, Keng Siang Lee, Danyal Khan, Julio C Furlan, Michael G Fehlings, James S Harrop, Carl Moritz Zipser, Ricardo Rodrigues-Pinto, James Milligan, Ellen Sarewitz, Armin Curt, Vafa Rahimi-Movaghar, Bizhan Aarabi, Timothy F Boerger, Lindsay Tetreault, Robert Chen, James D Guest, Sukhvinder Kalsi-Ryan, Iwan Sadler, Shirley Widdop, Angus Gk McNair, Brian K Kwon, Mark RN Kotter, AO Spine RECODE-DCM Steering Committee
Jul 10, 2022
INTRODUCTION: Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation and outcome comparison across studies. This limitation can be reversed by...
Increasing awareness of degenerative cervical myelopathy
Carl M Zipser, Konstantinos Margetis, Karlo M Pedro, Armin Curt, Michael Fehlings, Iwan Sadler, Lindsay Tetreault, Benjamin M Davies, AO Spine RECODE DCM Steering Committee, Members of the Diagnostic Criteria Working Group
Nov 02, 2021
Degenerative cervical myelopathy (DCM) is a common non-traumatic spinal cord disorder and characterized by progressive neurological impairment. Generally, it is still underdiagnosed and referral to spine specialists is often...
Clinical outcome measures and their evidence base in degenerative cervical myelopathy
Alvaro Yanez Touzet, Aniqah Bhatti, Esmee Dohle, Faheem Bhatti, Keng Siang Lee, Julio C Furlan, Michael G Fehlings, James S Harrop, Carl Moritz Zipser, Ricardo Rodrigues-Pinto, James Milligan, Ellen Sarewitz, Armin Curt, Vafa Rahimi-Movaghar, Bizhan Aarabi, Timothy F Boerger, Lindsay Tetreault, Robert Chen, James D Guest, Sukhvinder Kalsi-Ryan, Angus Gk McNair, Mark Kotter, Benjamin Davies, AO Spine RECODE-DCM Steering Committee
Jan 28, 2022
Establishing Diagnostic Criteria for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 3].
Bryn Hilton, Emma L Gardner, Zhilin Jiang, Lindsay Tetreault, Jamie RF Wilson, Carl Moritz Zipser, K Daniel Riew, James D Guest, James S Harrop, Michael G Fehlings, Ricardo Rodrigues-Pinto, Vafa Rahimi-Movaghar, Bizhan Aarabi, Paul A Koljonen, Mark RN Kotter, Benjamin M Davies, Brian K Kwon
Mar 20, 2022
STUDY DESIGN: Narrative review. OBJECTIVES: To discuss the importance of establishing diagnostic criteria in Degenerative Cervical Myelopathy (DCM), including factors that must be taken into account and challenges that must be...
Prevailing Outcome Themes Reported by People With Degenerative Cervical Myelopathy
Danyal Zaman Khan, Siobhan Mairead Fitzpatrick, Bryn Hilton, Angus Gk McNair, Ellen Sarewitz, Benjamin Marshall Davies, Mark RN Kotter, AO Spine Knowledge Forum Spinal Cord Injury
Feb 26, 2021
BACKGROUND: Degenerative cervical myelopathy (DCM) arises when arthritic changes of the cervical spine cause compression and a progressive injury to the spinal cord. It is common and potentially disabling. People with DCM have...
The development of lived experience-centered word clouds to support research uncertainty gathering in degenerative cervical myelopathy
Benjamin M Davies, Oliver D Mowforth, Danyal Z Khan, Xiaoyu Yang, Sybil RL Stacpoole, Olesja Hazenbiller, Toto Gronlund, Lindsay Tetreault, Sukhvinder Kalsi-Ryan, Michelle L Starkey, Iwan Sadler, Ellen Sarewitz, Delphine Houlton, Julia Carter, Evangeline Howard, Vafa Rahimi-Movaghar, James D Guest, Bizhan Aarabi, Brian K Kwon, Shekar N Kurpad, James Harrop, Jefferson R Wilson, Robert Grossman, Emma K Smith, Angus Gk McNair, Michael G Fehlings, Mark RN Kotter
Aug 20, 2021
OBJECTIVES: AO Spine REsearch objectives and Common Data Elements for Degenerative Cervical Myelopathy [RECODE-DCM] is a multi-stakeholder consensus process aiming to promote research efficiency in DCM. It aims to establish the...
Audit cervical cervical stenosis common data elements (CDE) Consensus Core Outcomes in Effectiveness Trials (COMET) dataset Delphi disc herniation James Lind Alliance (JLA) myelopathy OPLL outcome Protocol Research Priorities Spondylosis SURVEILLANCE Word Cloud Consensus Health Priorities Humans Randomized Controlled Trials as Topic Spinal Cord Diseases Surveys and Questionnaires uncertainty
Research activity amongst DCM research priorities.
Ben Grodzinski, Harry Bestwick, Faheem Bhatti, Rory Durham, Maaz Khan, Celine Iswarya Partha Sarathi, Jye Quan Teh, Oliver Mowforth, Benjamin Davies
May 12, 2021
INTRODUCTION: Degenerative cervical myelopathy (DCM) is a progressive neurodegenerative disorder. DCM is common (estimated prevalence, 2% of adults) and significantly impacts quality of life. The AO Spine RECODE-DCM (Research...
The development of lived experience-centered word clouds to support research uncertainty gathering in degenerative cervical myelopathy
Benjamin M Davies, Oliver D Mowforth, Danyal Z Khan, Xiaoyu Yang, Sybil R L Stacpoole, Olesja Hazenbiller, Toto Gronlund, Lindsay Tetreault, Sukhvinder Kalsi-Ryan, Michelle L Starkey, Iwan Sadler, Ellen Sarewitz, Delphine Houlton, Julia Carter, Evangeline Howard, Vafa Rahimi-Movaghar, James D Guest, Bizhan Aarabi, Brian K Kwon, Shekar N Kurpad, James Harrop, Jefferson R Wilson, Robert Grossman, Emma K Smith, Angus G K McNair, Michael G Fehlings, Mark R N Kotter
Jul 28, 2021
Objectives
AO Spine REsearch objectives and Common Data Elements for Degenerative Cervical Myelopathy [RECODE-DCM] is a multi-stakeholder consensus process aiming to promote research efficiency in DCM. It aims to...
SURVEILLANCE cervical Protocol Research Priorities Spondylosis Audit myelopathy disc herniation outcome Consensus OPLL Delphi dataset cervical stenosis Word Cloud common data elements (CDE) Core Outcomes in Effectiveness Trials (COMET) James Lind Alliance (JLA) Humans Spinal Cord Diseases uncertainty Health Priorities Randomized Controlled Trials as Topic Surveys and Questionnaires
Published by: Trials
The development of lived experience-centered word clouds to support research uncertainty gathering in degenerative cervical myelopathy
Benjamin M. Davies, Oliver D. Mowforth, Danyal Z. Khan, Xiaoyu Yang, Sybil R. L. Stacpoole, Olesja Hazenbiller, Toto Gronlund, Lindsay Tetreault, Sukhvinder Kalsi-Ryan, Michelle L. Starkey, Iwan Sadler, Ellen Sarewitz, Delphine Houlton, Julia Carter, Evangeline Howard, Vafa Rahimi-Movaghar, James D. Guest, Bizhan Aarabi, Brian K. Kwon, Shekar N. Kurpad, James Harrop, Jefferson R. Wilson, Robert Grossman, Emma K. Smith, Angus G.K. McNair, Michael G. Fehlings, Mark R. N. Kotter
Jun 25, 2021
Abstract: Objectives: AO Spine REsearch objectives and Common Data Elements for Degenerative Cervical Myelopathy [RECODE-DCM] is a multi-stakeholder consensus process aiming to promote research efficiency in DCM. It aims to...
Provision and Perception of Physiotherapy in the Nonoperative Management of Degenerative Cervical Myelopathy (DCM)
Max B Butler, Oliver D Mowforth, Abdul Badran, Michelle Starkey, Timothy Boerger, Iwan Sadler, Julia Tabrah, Caroline Treanor, Lucy Cameron Grad Dip Phys, Sukhvinder Kalsi-Ryan, Rodney J Laing, Benjamin M Davies, Mark RN Kotter
Sep 04, 2020
STUDY DESIGN: Cross-sectional survey. OBJECTIVES: Degenerative cervical myelopathy (DCM) is a common syndrome of acquired spinal cord impairment caused by canal stenosis secondary to arthritic changes of the spine. International...
Can co-authorship networks be used to predict author research impact? A machine-learning based analysis within the field of degenerative cervical myelopathy research
Introduction: Degenerative Cervical Myelopathy (DCM) is a common and disabling condition, with a relatively modest research capacity. In order to accelerate knowledge discovery, the AO Spine RECODE-DCM project has recently...
Can co-authorship networks be used to predict author research impact? A machine-learning based analysis within the field of degenerative cervical myelopathy research.
INTRODUCTION: Degenerative Cervical Myelopathy (DCM) is a common and disabling condition, with a relatively modest research capacity. In order to accelerate knowledge discovery, the AO Spine RECODE-DCM project has recently...
External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial
The prison-based N-ALIVE pilot trial had undertaken to notify the Research Ethics Committee and participants if we had reason to believe that the N-ALIVE pilot trial would not proceed to the main trial. In this paper, we...
Supervising projects you don’t (fully) understand
Strategically important projects involve high stakes, uncertainty, and stakeholder complexity, with contingencies and risks typically surfacing repeatedly as the project evolves. This is challenging not only for the project...
Hospitalisation for degenerative cervical myelopathy in England
Edward Goacher, Richard Phillips, Oliver D Mowforth, Stefan Yordanov, Erlick Ac Pereira, Adrian Gardner, Nasir A Quraishi, Antony H Bateman, Andreas K Demetriades, Marcel Ivanov, Alexandru Budu, Edward Dyson, Guy Wynne-Jones, Benjamin M Davies, Mark RN Kotter, NIHR POLYFIX-DCM Consortia
Jun 07, 2022
PURPOSE: Degenerative cervical myelopathy (DCM) is the most common cause of adult spinal cord dysfunction worldwide. However, the current incidence of DCM is poorly understood. The Hospital Episode Statistics (HES) database...
Degenerative Cervical Myelopathy and the Aging Spine
Degenerative Cervical Myelopathy (DCM) is the most common cause of spinal cord injury in the world, but despite this, there remains many areas of uncertainty regarding the management of the condition. This special issue was...
The development of a dynamic, six-axis spine simulator
Background Context
Although a great deal of research has been completed to characterize the stiffness of spinal specimens, there remains a limited understanding of the spine in 6 df and there is a lack of data from...
Although a great deal of research has been completed to characterize the stiffness of spinal specimens, there remains a limited understanding of the spine in 6 df and there is a lack of data from...
Combined steering and direct tilt control for the enhancement of narrow tilting vehicle stability
Narrow tilting vehicles offer an opportunity to reduce both traffic congestion and carbon emissions by having a small road footprint, a low weight and a small frontal area. Their narrow track requires that they tilt into corners...
Development and validation of a MEDLINE search filter/hedge for degenerative cervical myelopathy.
BACKGROUND: Degenerative cervical myelopathy (DCM) is a common condition with many unmet clinical needs. Pooled analysis of studies is an important tool for advancing medical understanding. This process starts with a systematic...
A strong law of large numbers for branching processes
We demonstrate a novel strong law of large numbers for branching processes, with a simple proof via measure-theoretic manipulations and spine theory. Roughly speaking, any sequence of events that eventually occurs almost surely...
A strong law of large numbers for branching processes
We demonstrate a novel strong law of large numbers for branching processes, with a simple proof via measure-theoretic manipulations and spine theory. Roughly speaking, any sequence of events that eventually occurs almost surely...
The development of a dynamic, six-axis spine simulator
Background Context
Although a great deal of research has been completed to characterize the stiffness of spinal specimens, there remains a limited understanding of the spine in 6 df and there is a lack of data from...
Although a great deal of research has been completed to characterize the stiffness of spinal specimens, there remains a limited understanding of the spine in 6 df and there is a lack of data from...
Phonotactic steering and representation of directional information in the ascending auditory pathway of a cricket.
Directional hearing is crucial for animals depending on acoustic signals to locate a mate. We focused on crickets to explore the reliability of directional information forwarded to the brain by the ascending auditory interneuron...
The equivalence of multi-axis spine systems
Timothy Holsgrove, Dhara Amin, Sonia Ramos Pascual, Boyin Ding, William Welch, Sabina Gheduzzi, Anthony Miles, Beth Winkelstein, John Costi
Mar 21, 2018
The complexity of multi-axis spine testing often makes it challenging to compare results from different studies. The aim of this work was to develop and implement a standardized testing protocol across three six-axis spine...
Multi-axis Six-axis Spine simulator Spine testing Test machines Test systems /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/2700/2732 name=Orthopedics and Sports Medicine /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2742 name=Rehabilitation
The equivalence of multi-axis spine systems
Timothy Holsgrove, Dhara Amin, Sonia Ramos Pascual, Boyin Ding, William Welch, Sabina Gheduzzi, Anthony Miles, Beth Winkelstein, John Costi
Mar 21, 2018
The complexity of multi-axis spine testing often makes it challenging to compare results from different studies. The aim of this work was to develop and implement a standardized testing protocol across three six-axis spine...
Multi-axis Six-axis Spine simulator Spine testing Test machines Test systems /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/2700/2732 name=Orthopedics and Sports Medicine /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2742 name=Rehabilitation
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