Search
Results: 29061
Nomogram predicting the probability of spontaneous stone passage in patients presenting with acute ureteric colic.
Chuanyu Gao, Max Peters, Piet Kurver, Thineskrishna Anbarasan, Keerthanaa Jayaraajan, Todd Manning, Sophia Cashman, Arjun Nambiar, Marcus Cumberbatch, Benjamin W Lamb, Robert Pickard, Paul Erotocritou, Daron Smith, Veeru Kasivisvanathan, Taimur T Shah, BURST Collaborative MIMIC Study Group
Jul 27, 2022
OBJECTIVES: To develop a nomogram that could predict spontaneous stone passage (SSP) in patients presenting with acute ureteric colic who are suitable for conservative management. SUBJECT/PATIENTS: A 2517 patient dataset was...
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Lourdes Ortiz-Fernández, Francisco David Carmona, Raquel López-Mejías, Maria Francisca González-Escribano, Paul A Lyons, Ann W Morgan, Amr H Sawalha, Peter A Merkel, Kenneth GC Smith, Miguel A González-Gay, Javier Martín, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group Spanish GCA Study Group
Apr 18, 2018
OBJETIVE: Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we...
Autoantibodies outcomes research systemic sclerosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Case-Control Studies Epigenesis Genetic Female Genetic Loci Genetic Predisposition to Disease Giant Cell Arteritis HLA-DQ Antigens HLA-DQ beta-Chains Humans Jumonji Domain-Containing Histone Demethylases Linkage Disequilibrium Male Phenotype Polymorphism Single Nucleotide Protein Array Analysis Systemic Vasculitis Takayasu arteritis
Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries
Mindy Goldman, Marc Germain, Yves Grégoire, Ralph R Vassallo, Hany Kamel, Marjorie Bravo, David O Irving, Emanuele Di Angelantonio, Whitney R Steele, Sheila F O'Brien, Biomedical Excellence for Safer Transfusion Collaborative (BEST) Investigators
Jan 29, 2019
BACKGROUND: Some countries impose an upper age limit on whole blood and double RBC donation while others do not. We evaluated the safety of blood donation in older individuals (≥71 years), and their contribution to the blood...
Investigation and Management of Apparently Sporadic Central Nervous System Haemangioblastoma for Evidence of Von Hippel–Lindau Disease
Hugh Furness, Louay Salfity, Johanna Devereux, Dorothy Halliday, Helen Hanson, Deborah M. Ruddy, UK VHL Study Group UK VHL Study Group, Neha Shah, George Sultana, Emma R. Woodward, Richard N. Sandford, Katie M. Snape, Eamonn R. Maher
Sep 17, 2021
Haemangioblastomas are rare, highly vascularised tumours that typically occur in the cerebellum, brain stem and spinal cord. Up to a third of individuals with a haemangioblastoma will have von Hippel–Lindau (VHL) disease....
The British Neurosurgical Trainee Research Collaborative
Aswin Chari, Aimun A Jamjoom, Ellie Edlmann, Aminul I Ahmed, Ian C Coulter, Ruichong Ma, Paul May, Paul M Brennan, Peter JA Hutchinson, Angelos G Kolias, British Neurosurgical Trainee Research Collaborative
Nov 28, 2018
Since its inception in 2012, the British Neurosurgical Trainee Research Collaborative (BNTRC) has established itself as a robust example of a trainee-led research collaborative. This article summarises the work of the...
Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis.
David RW Jayne, Annette N Bruchfeld, Lorraine Harper, Matthias Schaier, Michael C Venning, Patrick Hamilton, Volker Burst, Franziska Grundmann, Michel Jadoul, István Szombati, Vladimír Tesař, Mårten Segelmark, Antonia Potarca, Thomas J Schall, Pirow Bekker, CLEAR Study Group
May 13, 2019
Alternative C activation is involved in the pathogenesis of ANCA-associated vasculitis. However, glucocorticoids used as treatment contribute to the morbidity and mortality of vasculitis. We determined whether avacopan (CCX168)...
ANCA ANCA-associated vasculitis avacopan complement complement 5a complement 5a receptor Adult Aged Aniline Compounds Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis cyclophosphamide Double-Blind Method Drug Therapy Combination Female Glucocorticoids Humans Immunosuppressive Agents Male Middle Aged Nipecotic Acids prednisone Receptor Anaphylatoxin C5a Rituximab Severity of Illness Index
New perspectives in eosinophilic granulomatosis with polyangiitis (EGPA)
Chiara Marvisi, Renato Alberto Sinico, Carlo Salvarani, David Jayne, Domenico Prisco, Benjamin Terrier, Giacomo Emmi, Augusto Vaglio, European EGPA Study Group
May 27, 2020
The European Eosinophilic Granulomatosis with Polyangiitis (EGPA) study group first gathered in Firenze in December 2018. The discussion was centred around the clinical and therapeutic needs in EGPA which still remain unmet....
Variations in hemoglobin measurement and eligibility criteria across blood donation services are associated with differing low-hemoglobin deferral rates
Saurabh Zalpuri, Bas Romeijn, Elias Allara, Mindy Goldman, Hany Kamel, Jed Gorlin, Ralph Vassallo, Yves Grégoire, Naoko Goto, Peter Flanagan, Joanna Speedy, Andreas Buser, Jose Mauro Kutner, Karin Magnussen, Johanna Castrén, Liz Culler, Harry Sussmann, Femmeke J Prinsze, Kevin Belanger, Veerle Compernolle, Pierre Tiberghien, Jose Manuel Cardenas, Manish J Gandhi, Kamille A West, Cheuk-Kwong Lee, Sian James, Deanne Wells, Laurie J Sutor, Silvano Wendel, Matthew Coleman, Axel Seltsam, Kimberly Roden, Whitney R Steele, Milos Bohonek, Ramir Alcantara, Emanuele Di Angelantonio, Katja van den Hurk, BEST Collaborative Study Group
Jan 10, 2020
BACKGROUND: Determination of blood donor hemoglobin (Hb) levels is a pre-requisite to ensure donor safety and blood product quality. We aimed to identify Hb measurement practices across blood donation services and to what extent...
Effectiveness of a quality improvement collaborative in reducing time to surgery for patients requiring emergency cholecystectomy.
JR Bamber, TJ Stephens, DA Cromwell, E Duncan, GP Martin, NF Quiney, JF Abercrombie, IJ Beckingham, Cholecystectomy Quality Improvement Collaborative
Oct 11, 2019
BACKGROUND: Acute gallstone disease is a high-volume emergency general surgery presentation with wide variations in the quality of care provided across the UK. This controlled cohort evaluation assessed whether participation in...
A Modified Progressive Supranuclear Palsy Rating Scale.
Marie-Therese Grötsch, Gesine Respondek, Carlo Colosimo, Yaroslau Compta, Jean Christophe Corvol, Joaquim Ferreira, Meret Koroni Huber, Martin Klietz, Lea FM Krey, Johannes Levin, Milica Jecmenica-Lukic, Daniel Macías-García, Wassilios G Meissner, Pablo Mir, Huw Morris, Christer Nilsson, James B Rowe, Klaus Seppi, Maria Stamelou, John C van Swieten, Gregor Wenning, Teodoro del Ser, Lawrence I Golbe, Günter U Höglinger, the ProPSP Study Group, and the Movement Disorder Society-Endorsed PSP Study Group Describe PSP Study Group
Jan 26, 2021
BACKGROUND: The Progressive Supranuclear Palsy Rating Scale is a prospectively validated physician-rated measure of disease severity for progressive supranuclear palsy. We hypothesized that, according to experts' opinion...
Twice-Daily Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex Reduces Methamphetamine Craving
Objectives: Transcranial magnetic stimulation (TMS) holds potential promise as a therapeutic modality for disorders of addiction. Our previous findings indicate that high-frequency repetitive transcranial magnetic stimulation...
Twice-Daily Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex Reduces Methamphetamine Craving
OBJECTIVES: Transcranial magnetic stimulation (TMS) holds potential promise as a therapeutic modality for disorders of addiction. Our previous findings indicate that high-frequency repetitive transcranial magnetic stimulation...
Collaborative facilitation and collaborative inhibition in virtual environments
Worldwide, organizations and small and medium-sized enterprises have already disruptively changed in many ways their physiological inner mechanisms, because of information and communication technologies (ICT) revolution....
Collaborative creativity in instrumental group music learning as a site for enhancing pupil wellbeing
This study explores the nature of the elements that co-influence collaborative creativity in instrumental group music learning and the intrinsic potential for enhancing pupil wellbeing as evidenced in a particular...
The association of mammographic density with risk of contralateral breast cancer and change in density with treatment in the WECARE study.
Julia A Knight, Kristina M Blackmore, Jing Fan, Kathleen E Malone, Esther M John, Charles F Lynch, Celine M Vachon, Leslie Bernstein, Jennifer D Brooks, Anne S Reiner, Xiaolin Liang, Meghan Woods, WECARE Study Collaborative Group, Jonine L Bernstein
Feb 07, 2020
BACKGROUND: Mammographic density (MD) is an established predictor of risk of a first breast cancer, but the relationship of MD to contralateral breast cancer (CBC) risk is not clear, including the roles of age, mammogram timing...
Twice-Daily Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex Reduces Methamphetamine Craving
Transcranial magnetic stimulation (TMS) holds potential promise as a therapeutic modality for disorders of addiction. Our previous findings indicate that high-frequency repetitive transcranial magnetic stimulation (rTMS) over...
Published by: Frontiers in neuroscience
Collaborative Writing in the Intelligence Community
With new and evolving technology and ever-increasing remote collaboration, intelligence reporting processes are at a crossroads. Key questions about how best to collaboratively produce reports to get the right information to the...
Published by: IGI Global Scientific Publishing
CYP2D6 phenotype, tamoxifen, and risk of contralateral breast cancer in the WECARE Study.
Jennifer D Brooks, Elizabeth A Comen, Anne S Reiner, Irene Orlow, Siok F Leong, Xiaolin Liang, Lene Mellemkjær, Julia A Knight, Charles F Lynch, Esther M John, Leslie Bernstein, Meghan Woods, David R Doody, WECARE Study Collaborative Group, Kathleen E Malone, Jonine L Bernstein
Feb 18, 2019
BACKGROUND: Tamoxifen treatment greatly reduces a woman's risk of developing a second primary breast cancer. There is, however, substantial variability in treatment response, some of which may be attributed to germline genetic...
CYP2D6 Contralateral breast cancer Tamoxifen Adult Aged Antineoplastic Agents Hormonal Breast Neoplasms Case-Control Studies Cytochrome P-450 CYP2D6 Female Follow-Up Studies Humans Middle Aged Neoplasms Second Primary Pharmacogenomic Variants Polymorphism Single Nucleotide Tamoxifen Treatment Outcome
Research in progress--LungSEARCH
UNLABELLED: Low-dose CT screening for lung cancer is effective but expensive. Therefore, cheaper or more focused screening strategies may be required. LungSEARCH is a randomised prospective trial of 1568 high-risk individuals...
Teachers' Attitudes Towards the Effectiveness of Collaborative Reflection Support Method
This study aimed to explore how minute paper method (MPM) reconstructs the attitude towards the collaborative reflection among ten primary school English teachers with different levels of achievement goal (AG) and community...
Published by: IGI Global Scientific Publishing
The Bath University rugby shuttle test (BURST)
Purpose: This study presents an exercise protocol utilizing movement patterns specific to rugby union forward and assesses the reproducibility of scores from this test.
Methods: After habituation, eight participants (mean...
Methods: After habituation, eight participants (mean...
A Study of the Motivation of Collaborative Consumption and the Moderating Effect of Perceived Social Distance
Youngkeun Choi
Jan 01, 2022
The purpose of the present study was to examine the relationships between motivation factors and collaborative consumption engagement and explore the moderating effect of perceived social distance on that relationship. For this...
Published by: IGI Global Scientific Publishing
Emergency surgery for splenic flexure cancer
Nicola de'Angelis, Eloy Espin, Frederic Ris, Filippo Landi, Bertrand Le Roy, Federico Coccolini, Valerio Celentano, Angela Gurrado, Denis Pezet, Giorgio Bianchi, Riccardo Memeo, Giulio C Vitali, Alejandro Solis, Christine Denet, Salomone Di Saverio, Gian Luigi de'Angelis, Miquel Kraft, Paula Gonzálvez-Guardiola, Aine Stakelum, Fausto Catena, David Fuks, Des C Winter, Mario Testini, Aleix Martínez-Pérez, SFC Study Group
Apr 30, 2021
BACKGROUND: The effectiveness of surgical treatment for splenic flexure carcinomas (SFCs) in emergency settings remains unexplored. This study aims to compare the perioperative and long-term outcomes of different alternatives...
Effects of Different Leadership Styles on Cognitive Engagement in Online Collaborative Learning
The collaborative learning approach as a universal teaching strategy is widely used in online learning. It is proven that the group leader has an important impact on group collaborative knowledge construction in online...
Published by: IGI Global Scientific Publishing
An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment.
Marcus Jepson, Daisy Elliott, Carmel Conefrey, Julia Wade, Leila Rooshenas, Caroline Wilson, David Beard, Jane M Blazeby, Alison Birtle, Alison Halliday, Rob Stein, Jenny L Donovan, CSAW study group, Chemorad study group, POUT study group, ACST-2 study group, OPTIMA prelim study group
Aug 23, 2018
OBJECTIVES: To explore how the concept of randomization is described by clinicians and understood by patients in randomized controlled trials (RCTs) and how it contributes to patient understanding and recruitment. STUDY DESIGN...
Patient information qualitative research randomization Randomized controlled trials Recruitment Recruitment to RCTs Comprehension Decision Making Computer-Assisted Gambling Humans metaphor Patient Education as Topic Patient Selection qualitative research Random Allocation Randomized Controlled Trials as Topic United Kingdom
|
|< |
< |
1 |