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When has service provision for transient ischaemic attack improved enough? A discrete event simulation economic modelling study.
Pelham Barton, James P Sheppard, Cristina M Penaloza-Ramos, Sue Jowett, Gary A Ford, Daniel Lasserson, Jonathan Mant, Ruth M Mellor, Tom Quinn, Peter M Rothwell, David Sandler, Don Sims, Richard J McManus, BBC CLAHRC investigators
May 21, 2018
OBJECTIVES: The aim of this study was to examine the impact of transient ischaemic attack (TIA) service modification in two hospitals on costs and clinical outcomes. DESIGN: Discrete event simulation model using data from...
economic modelling Health Services Secondary Care Secondary Prevention stroke Aged Ambulatory Care Ambulatory Care Facilities Costs and Cost Analysis Delivery of Health Care England Female Follow-Up Studies Humans Ischemic Attack Transient Male Models Economic Patient Acceptance of Health Care Quality Improvement Referral and Consultation Secondary Care Secondary Prevention Treatment Outcome
Prevalence and predictors of hospital prealerting in acute stroke
JP Sheppard, A Lindenmeyer, RM Mellor, S Greenfield, J Mant, T Quinn, A Rosser, D Sandler, D Sims, M Ward, RJ McManus, CLAHRC BBC investigators
May 02, 2018
BACKGROUND: Thrombolysis can significantly reduce the burden of stroke but the time window for safe and effective treatment is short. In patients travelling to hospital via ambulance, the sending of a 'prealert' message can...
Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury
Ali Teymoori, Anastasia Gorbunova, Fardzadeh E. Haghish, Ruben Real, Marina Zeldovich, Yi-Jhen Wu, Suzanne Polinder, Thomas Asendorf, David Menon, CENTER-TBI Investigators and Participants CENTER-TBI Investigators and Participants, Nicole v. Steinbüchel
Mar 25, 2020
Background: The dimensionality of depression and anxiety instruments have recently been a source of controversy. Objectives and Design: In a European-wide sample of patients after Traumatic Brain Injury (TBI), we aim to examine...
The United Kingdom Childhood Cancer Study
UK Childhood Cancer Study Investigators
Feb 21, 2020
An investigation into the possible causes of childhood cancer has been carried out throughout England, Scotland and Wales over the period 1991-1998. All children known to be suffering from one or other type of the disease over...
Discursive Construction of News Values in the Headline
The paper makes a discursive analysis of the news value construction in the headlines of new media news. The data chosen is 59 news headlines on coverage of Zimbabwe Crisis released in the apps of BBC from November 6th to...
Published by: IGI Global Scientific Publishing
Calling All Doctor Who Fans: Literary Society Celebrates Show Milestone
Winthrop University
Jan 01, 0001
The celebration begins at 7 p.m. in Dinkins Auditorium and features prizes, trivia and contests. Doctor Who is a popular science-fiction time-travel show on BBC in its 50th year.
Published by: Winthrop University
Mindfulness at Cam
The University of Cambridge and the National Institute for Health Research and Collaboration for Leadership in Applied Health Research and Care (NIHR CLAHRC), East of England, are currently undertaking research into the...
SnRE at the BBC
Clive Upton
Sep 30, 2014
Two strands - perhaps "strains" might at times be thought a more accurate word -exist within dialectology. One, geographical and historical, charts linguistic variation on the ground and seeks to study language in its diachronic...
Published by: Atlantic Provinces Linguistic Association
SnRE at the BBC
Clive Upton
Sep 30, 2014
Two strands - perhaps "strains" might at times be thought a more accurate word -exist within dialectology. One, geographical and historical, charts linguistic variation on the ground and seeks to study language in its diachronic...
Published by: Atlantic Provinces Linguistic Association
Diffuse Intracranial Injury Patterns Are Associated with Impaired Cerebrovascular Reactivity in Adult Traumatic Brain Injury
Frederick A Zeiler, François Mathieu, Miguel Monteiro, Ben Glocker, Ari Ercole, Erta Beqiri, Manuel Cabeleira, Nino Stocchetti, Peter Smielewski, Marek Czosnyka, Virginia Newcombe, David K Menon, the CENTER-TBI High-Resolution ICU (HR ICU) Sub-Study Participants and Investigators CENTER-TBI High-Resolution ICU (HR ICU) Sub-Study Participants and Investigators
Feb 28, 2020
Recent single-center retrospective analysis displayed the association between admission computed tomography (CT) markers of diffuse intracranial injury and worse cerebrovascular reactivity. The goal of this study was to further...
Brain death and postmortem organ donation
Ernest van Veen, Mathieu van der Jagt, Maryse C Cnossen, Andrew IR Maas, Inez D de Beaufort, David K Menon, Giuseppe Citerio, Nino Stocchetti, Wim JR Rietdijk, Jeroen TJM van Dijck, Erwin JO Kompanje, CENTER-TBI Investigators and Participants
Apr 14, 2020
BACKGROUND: We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation. METHODS: Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic...
Value of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm.
MJ Sweeting, P Ulug, J Roy, R Hultgren, R Indrakusuma, R Balm, MM Thompson, RJ Hinchliffe, SG Thompson, JT Powell, Ruptured Aneurysm Collaborators: AJAX Trial investigators, ECAR Trial investigators, IMPROVE Trial investigators: management committee, STAR Cohort investigators
Mar 12, 2018
Hall Fire at Owens Put Out After 24 Hours
Winthrop University
Jan 01, 0001
Fire investigators have been able to gain access to the building to begin their investigation. Winthrop officials are working to begin restoration to Bancroft Hall, Kinard Hall and the area outside the buildings.
Published by: Winthrop University
XVIIth Little Brain Big Brain
Little Brain Big Brain is a biannual meeting organized and attended by young investigators. Since its inception in 1989, this meeting has brought together promising junior researchers in neurogastroenterology. The XVIIth meeting...
Rock Hill Fire Department Provides Update on Owens Hall Fire
Winthrop University
Jan 01, 0001
The fire started outside the building on a small section of flat roof located where Owens Hall and Bancroft Annex join. Fire investigators reviewed and ruled out the mechanical room, HVAC and elevator systems.
Published by: Winthrop University
The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.
Inge MM Lakeman, Alexandra J van den Broek, Juliën AM Vos, Daniel R Barnes, Julian Adlard, Irene L Andrulis, Adalgeir Arason, Norbert Arnold, Banu K Arun, Judith Balmaña, Daniel Barrowdale, Javier Benitez, Ake Borg, Trinidad Caldés, Maria A Caligo, Wendy K Chung, Kathleen BM Claes, GEMO Study Collaborators, EMBRACE Collaborators, J Margriet Collée, Fergus J Couch, Mary B Daly, Joe Dennis, Mallika Dhawan, Susan M Domchek, Ros Eeles, Christoph Engel, D Gareth Evans, Lidia Feliubadaló, Lenka Foretova, Eitan Friedman, Debra Frost, Patricia A Ganz, Judy Garber, Simon A Gayther, Anne-Marie Gerdes, Andrew K Godwin, David E Goldgar, Eric Hahnen, Christopher R Hake, Ute Hamann, Frans BL Hogervorst, Maartje J Hooning, John L Hopper, Peter J Hulick, Evgeny N Imyanitov, OCGN Investigators, HEBON Investigators, kConFab Investigators, Claudine Isaacs, Louise Izatt, Anna Jakubowska, Paul A James, Ramunas Janavicius, Uffe Birk Jensen, Yue Jiao, Esther M John, Vijai Joseph, Beth Y Karlan, Carolien M Kets, Irene Konstantopoulou, Ava Kwong, Clémentine Legrand, Goska Leslie, Fabienne Lesueur, Jennifer T Loud, Jan Lubiński, Siranoush Manoukian, Lesley McGuffog, Austin Miller, Denise Molina Gomes, Marco Montagna, Emmanuelle Mouret-Fourme, Katherine L Nathanson, Susan L Neuhausen, Heli Nevanlinna, Joanne Ngeow Yuen Yie, Edith Olah, Olufunmilayo I Olopade, Sue K Park, Michael T Parsons, Paolo Peterlongo, Marion Piedmonte, Paolo Radice, Johanna Rantala, Gad Rennert, Harvey A Risch, Rita K Schmutzler, Priyanka Sharma, Jacques Simard, Christian F Singer, Zsofia Stadler, Dominique Stoppa-Lyonnet, Christian Sutter, Yen Yen Tan, Manuel R Teixeira, Soo Hwang Teo, Alex Teulé, Mads Thomassen, Darcy L Thull, Marc Tischkowitz, Amanda E Toland, Nadine Tung, Elizabeth J van Rensburg, Ana Vega, Barbara Wappenschmidt, Peter Devilee, Christi J van Asperen, Jonine L Bernstein, Kenneth Offit, Douglas F Easton, Matti A Rookus, Georgia Chenevix-Trench, Antonis C Antoniou, Mark Robson, Marjanka K Schmidt
Jul 08, 2021
PURPOSE: To evaluate the association between a previously published 313 variant-based breast cancer (BC) polygenic risk score (PRS313) and contralateral breast cancer (CBC) risk, in BRCA1 and BRCA2 pathogenic variant...
Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease.
Matthew Traylor, Poneh Adib-Samii, Denise Harold, Alzheimer's Disease Neuroimaging Initiative, UK Young Lacunar Stroke DNA resource International Stroke Genetics Consortium (ISGC), Martin Dichgans, Julie Williams, Cathryn M Lewis, Hugh S Markus, METASTROKE, investigators International Genomics of Alzheimer's Project (IGAP)
Feb 23, 2016
Rewriting Women: A Feminist Examination of Lolita's and Pride and Prejudice's Costume and Revisionist Adaptations
Courtney A DuChene, Ms.
Jan 01, 0001
This project examines costume and revisionist media adaptations of Lolita and Pride and Prejudice to see how adapters have altered the texts in order to increase the agency of the female characters. It consists of four chapters...
Lolita Nabokov Kubrick Pride and Prejudice Bridget Jones' Diary Lizzie Bennet Diaries Una adaptations Arts and Humanities English Language and Literature Feminist, Gender, and Sexuality Studies Film and Media Studies Women's Studies
Published by: Ursinus College
Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants
Valentina Silvestri, Goska Leslie, Daniel R Barnes, CIMBA Group, Bjarni A Agnarsson, Kristiina Aittomäki, Elisa Alducci, Irene L Andrulis, Rosa B Barkardottir, Alicia Barroso, Daniel Barrowdale, Javier Benitez, Bernardo Bonanni, Ake Borg, Saundra S Buys, Trinidad Caldés, Maria A Caligo, Carlo Capalbo, Ian Campbell, Wendy K Chung, Kathleen BM Claes, Sarah V Colonna, Laura Cortesi, Fergus J Couch, Miguel de la Hoya, Orland Diez, Yuan Chun Ding, Susan Domchek, Douglas F Easton, Bent Ejlertsen, Christoph Engel, D Gareth Evans, Lidia Feliubadalò, Lenka Foretova, Florentia Fostira, Lajos Géczi, Anne-Marie Gerdes, Gord Glendon, Andrew K Godwin, David E Goldgar, Eric Hahnen, Frans BL Hogervorst, John L Hopper, Peter J Hulick, Claudine Isaacs, Angel Izquierdo, Paul A James, Ramunas Janavicius, Uffe Birk Jensen, Esther M John, Vijai Joseph, Irene Konstantopoulou, Allison W Kurian, Ava Kwong, Elisabetta Landucci, Fabienne Lesueur, Jennifer T Loud, Eva Machackova, Phuong L Mai, Keivan Majidzadeh-A, Siranoush Manoukian, Marco Montagna, Lidia Moserle, Anna Marie Mulligan, Katherine L Nathanson, Heli Nevanlinna, Joanne Ngeow, Liene Nikitina-Zake, Kenneth Offit, Edith Olah, Olufunmilayo I Olopade, Ana Osorio, Laura Papi, Sue K Park, Inge Sokilde Pedersen, Pedro Perez-Segura, Annabeth H Petersen, Pedro Pinto, Berardino Porfirio, Miquel Angel Pujana, Paolo Radice, Johanna Rantala, Muhammad U Rashid, Barak Rosenzweig, Maria Rossing, Marta Santamariña, Rita K Schmutzler, Leigha Senter, Jacques Simard, Christian F Singer, Angela R Solano, Melissa C Southey, Linda Steele, Zoe Steinsnyder, Dominique Stoppa-Lyonnet, Yen Yen Tan, Manuel R Teixeira, Soo H Teo, Mary Beth Terry, Mads Thomassen, Amanda E Toland, Sara Torres-Esquius, Nadine Tung, Christi J van Asperen, Ana Vega, Alessandra Viel, Jeroen Vierstraete, Barbara Wappenschmidt, Jeffrey N Weitzel, Greet Wieme, Sook-Yee Yoon, Kristin K Zorn, Lesley McGuffog, Michael T Parsons, Ute Hamann, Mark H Greene, Judy A Kirk, Susan L Neuhausen, Timothy R Rebbeck, Marc Tischkowitz, Georgia Chenevix-Trench, Antonis C Antoniou, Eitan Friedman, Laura Ottini
Sep 01, 2020
IMPORTANCE: The limited data on cancer phenotypes in men with germline BRCA1 and BRCA2 pathogenic variants (PVs) have hampered the development of evidence-based recommendations for early cancer detection and risk reduction in...
Towards a Better Understanding of Drone Forensics
Unmanned aerial vehicles (drones) have gained increased popularity as their innovative uses continue to expand across various fields. Despite their numerous beneficial uses, drones have unfortunately been misused, through many...
Published by: IGI Global Scientific Publishing
A fresh approach to evidence synthesis.
For most conservation interventions, insufficient evidence exists for investigators to be able to conduct a meta-analysis for each species or genus. However, by being apprised of studies that examine how a particular...
Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn's disease
Evangelos Stournaras, Wendi Qian, Apostolos Pappas, You Yi Hong, Rasha Shawky, UK IBD BioResource Investigators, Tim Raine, Miles Parkes, UK IBD Bioresource Investigators
Jul 20, 2020
OBJECTIVE: Thiopurines are widely used as maintenance therapy in inflammatory bowel disease (IBD) but the evidence base for their use is sparse and their role increasingly questioned. Using the largest series reported to date...
Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4)
Richard J McManus, Jonathan Mant, Marloes Franssen, Alecia Nickless, Claire Schwartz, James Hodgkinson, Peter Bradburn, Andrew Farmer, Sabrina Grant, Sheila M Greenfield, Carl Heneghan, Susan Jowett, Una Martin, Siobhan Milner, Mark Monahan, Sam Mort, Emma Ogburn, Rafael Perera-Salazar, Syed Ahmar Shah, Ly-Mee Yu, Lionel Tarassenko, FD Richard Hobbs, TASMINH4 investigators
May 18, 2018
BACKGROUND: Studies evaluating titration of antihypertensive medication using self-monitoring give contradictory findings and the precise place of telemonitoring over self-monitoring alone is unclear. The TASMINH4 trial aimed to...
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