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Results: 29
Foix-Chavany-Marie syndrome secondary to bilateral traumatic operculum injury.
This report describes a case of a 62-year-old man who developed Foix-Chavany-Marie syndrome subsequent to traumatic brain injury. The initial presentation of the syndrome was profound loss of voluntary control of orofacial...
Neurological update
Coronavirus Disease 2019 is predominantly a disorder of the respiratory system, but neurological complications have been recognised since early in the pandemic. The major pathophysiological processes leading to neurological...
Neurological update
Abstract: Coronavirus Disease 2019 is predominantly a disorder of the respiratory system, but neurological complications have been recognised since early in the pandemic. The major pathophysiological processes leading to...
A method to isolate and cryopreserve cerebrospinal fluid mononuclear cells from external ventricular drains to investigate immunological processes in acute brain injuries.
The inflammatory response to acute brain injuries is a key contributor to subsequent outcome. The study of local central nervous system inflammatory responses is hindered by raised intracranial pressure precluding cerebrospinal...
Cholinergic modulation of Up-Down states in the mouse medial entorhinal cortex in vitro.
Y Audrey Hay, Przemyslaw Jarzebowski, Yu Zhang, Richard Digby, Viktoria Brendel, Ole Paulsen, Vincent Magloire
Nov 03, 2020
Cholinergic tone is high during wake and rapid eye movement sleep and lower during slow wave sleep (SWS). Nevertheless, the low tone of acetylcholine during SWS modulates sharp wave ripple incidence in the hippocampus and slow...
The Ursinus Weekly, January 12, 1959
Radio station to be set-up with student body consent Petersen and Drewniak are honored by MAC Summer study abroad announced by IIE May Day Air Force offers commissions to college grads Frosh present "Marooned" on Friday...
Ursinus College Collegeville Pennsylvania newspaper radio station Football Pete Petersen Mike Drewniak May Day pageant Canterbury Club Chi Alpha Beta Sigma Lambda Harry C. Symons Demas Omega Chi Ira Progoff YMCA YWCA Du Pont Company Tau Sigma Gamma Brownback-Anders pre-medical society Cherrie Soper Soccer badminton Basketball wrestling Beardwood Chemical Society Belifiore Dillio Lester Lanin cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Ursinus College Bulletin, February 1977
Andrea A. Vaughan, Blanche Allen, Richard P. Richter, Mary Lou Gruber, Andy Vaughan, Harry C. Symons, John Pilgrim, Joyce Henry
Jan 01, 0001
President's memo In search of future alumni Up from the South he arose or the Carterites have gone to Washington Focus on economics and business administration Executive assistant to President named Scholarship established ...
Ursinus College Collegeville Pennsylvania alumni Deaths Marriages Admissions Department Jimmy Carter Economics Department James P. Craft William T. Parsons field hockey Joan Aikens Harold L. Gold Dorothy Shelley Higher Education Social History United States History
Published by: Ursinus College
Ursinus College Alumni Journal, March 1960
Richard T. Schellhase, Calvin D. Yost, Roger P. Staiger, Raymond V. Gurzynski, Blanche B. Schultz, Donald L. Helfferich, J. William D. Wright, Harry C. Symons, Garfield Sieber Pancoast, William LeRoy Fink, William Schuyler Pettit, Fred Binder, Flora Rahn Lentz, William J. Phillips
Jan 01, 0001
President's page 1960 - A democratic president Faith in the individual Teachers are made Alumni elections - watch for your ballot in April On recruiting Recent changes in the Education Department Attention: Alumna at...
Ursinus College Collegeville Pennsylvania alumni Deaths Marriages Bertha Francis John R. Clarke James J. Lamond Flora Rahn Lentz John Lentz Allan Lake Rice Robert C. Stein Helmut H. Behling field hockey Football wrestling Basketball track team Alvin L. Weiss Higher Education Social History United States History
Published by: Ursinus College
The Ursinus Weekly, October 26, 1959
Folk songs and ballads are topic of Jemison on Nov. 4 Sorority rushees pledged on Sat.; Hold breakfasts International House features folk balladeers YM-YW seminar plans juvenile crime discussion Three lectures on renaissance...
Ursinus College Collegeville Pennsylvania newspaper Eugene Jemison International House sororities fraternities rushing YMCA YWCA Charles Pratt National Renaissance Society Founders Day William F. Dannehower student government Business Administration Club Frederick M. Richards Brownback-Anders pre-medical society International Relations Club Phil Rowe Whitians Freeland Hall Robert H. Handwerk Football field hockey Soccer cross country Vernon Morgan Harry C. Symons J. Allen Minnich Newman Club Canterbury Club cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, May 1, 1987
Jean M. Kiss, Lora L. Hart, Anne Woodworth, Steve Gall, Angela M. Salas, Richard P. Richter, Jeanne Radwanski, Vince Leskusky, Jill Griffiths, Susan Mockus, Andy Standeven, Dave Kulp, Joseph F. Pirro, Maria D'Arcangelo, Andrea Power, Vicky Scharuda, Marge Hamilton
Jan 01, 0001
Will Ursinus Make the Grade? Commuters Recognized Student Apathy a Farce Beatles Now Available on Disc "Dougy" is King to Sig Rho Notes: Summer Tennis Strategies Offered; Continuing Ed. Becomes Assertive; Physical Education...
Ursinus College Collegeville Pennsylvania newspaper Harry Symons Jeff Page F. Donald Zucker Myrin Library Geoffrey Dolman Fishing Club softball baseball Dave Kulp tennis lacrosse golf track team Beth Bingaman Scott Klee Mike Ignatowicz Douglas Davis Sigma Rho Lambda Evening school Health and Physical Education Club College band Beatles AIDS fundraising commuting students Middle States Commission cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections.
Zsofi Digby, Panagiotis Tourlomousis, James Rooney, Joseph P Boyle, Betsaida Bibo-Verdugo, Robert J Pickering, Steven J Webster, Thomas P Monie, Lee J Hopkins, Nobuhiko Kayagaki, Guy S Salvesen, Soren Warming, Lucy Weinert, Clare E Bryant
Aug 06, 2021
Zoonotic pathogens, such as COVID-19, reside in animal hosts before jumping species to infect humans. The Carnivora, like mink, carry many zoonoses, yet how diversity in host immune genes across species affect pathogen carriage...
Carnivora NLRC4 NLRP3 Caspase 1 caspase 11 caspase 4 inflammasome Animals Carnivora Caspase 1 Caspase 8 Caspases Initiator Cell Death Cell Line evolution Molecular Humans Inflammasomes Interleukin-1beta Lipopolysaccharides MACROPHAGES Mice Mice Inbred C57BL NLR proteins Recombinant Fusion Proteins Recombinant Proteins Salmonella typhi Zoonoses
Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.
Catherine M Scahill, Zsofia Digby, Ian M Sealy, Sonia Wojciechowska, Richard J White, John E Collins, Derek L Stemple, Till Bartke, Marie E Mathers, E Elizabeth Patton, Elisabeth M Busch-Nentwich
Jun 20, 2018
KDM2A is a histone demethylase associated with transcriptional silencing, however very little is known about its in vivo role in development and disease. Here we demonstrate that loss of the orthologue kdm2aa in zebrafish causes...
Animals DNA Replication Disease Models Animal Epigenesis Genetic Exome Female Gene Expression Profiling Gene Expression Regulation Neoplastic Gene Knockout Techniques Jumonji Domain-Containing Histone Demethylases Male Melanoma Mutation Proto-Oncogene Proteins B-raf RNA Messenger Sequence Analysis RNA Zebrafish Zebrafish Proteins
The Influence of HIV on the Evolution of Mycobacterium tuberculosis.
Anastasia S Koch, Daniela Brites, David Stucki, Joanna C Evans, Ronnett Seldon, Alexa Heekes, Nicola Mulder, Mark Nicol, Tolu Oni, Valerie Mizrahi, Digby F Warner, Julian Parkhill, Sebastien Gagneux, Darren P Martin, Robert J Wilkinson
Sep 10, 2019
HIV significantly affects the immunological environment during tuberculosis coinfection, and therefore may influence the selective landscape upon which M. tuberculosis evolves. To test this hypothesis whole genome sequences were...
A high-resolution mRNA expression time course of embryonic development in zebrafish.
Richard J White, John E Collins, Ian M Sealy, Neha Wali, Christopher M Dooley, Zsofia Digby, Derek L Stemple, Daniel N Murphy, Konstantinos Billis, Thibaut Hourlier, Anja Füllgrabe, Matthew P Davis, Anton J Enright, Elisabeth M Busch-Nentwich
Feb 12, 2018
We have produced an mRNA expression time course of zebrafish development across 18 time points from 1 cell to 5 days post-fertilisation sampling individual and pools of embryos. Using poly(A) pulldown stranded RNA-seq and a 3'...
Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function.
The Ursinus Weekly, January 14, 1957
Lawrence C. Foard, Thomas M. McCabe, Walter W. Montgomery, Bruce MacGregor, Christopher Rohm, Warren Rybak
Jan 01, 0001
McClure releases statement on new funds for UC UC evaluation to be held in Feb. Committee begins work on Campus Chest plans "Y" to hear speaker Wed. WSGA plans forum on student government Frosh to present "Show boat" on...
Ursinus College Collegeville Pennsylvania newspaper Norman E. McClure Ralph F. Wismer accreditation Campus Chest YMCA YWCA Francis Bosworth Curtain Club student government Canterbury Club George Busler Communion service Alpha Phi Epsilon John Townsend Carol Scheidhauer Bernard A. Colameco Barbara Spencer Delta Pi Thomas Zern Helen Balthaser David Mayberry Mary Jo Turtzo Harry C. Symons Who's who Chi Alpha Kappa Delta Kappa Hungary Sigma Rho Lambda Bruce Holcombe Millie Wisner John Haag Carolyn Brune Nancy Reese Henry D. Ruth St. John Terrell Belifiore Dillio Basketball badminton Everett M. Bailey Intramural Sports wrestling Evelyn Louise Eggenhofer George R. Herman Judith Shelly Allen Frank cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Effectiveness and safety of vedolizumab in inflammatory bowel disease patients aged 60 and over
Hajir Ibraheim, Mark A Samaan, Ashish Srinivasan, Oliver Brain, Jonathan Digby-Bell, Peter M Irving, Irena Norman, Issrah Jawad, Julia Biedermann, Ana Ibarra, Klaartje Bel Kok, Gareth Parkes, Joanna Rimmer, Elisabeta Compot, Miles Parkes, Jonathan Segal, Philip Oppong, Ailsa Hart, Bu'Hussain Hayee, Nick Powell
Feb 03, 2021
BACKGROUND: The GEMINI trials established the efficacy of vedolizumab in moderate-to-severe inflammatory bowel disease (IBD) and demonstrated a favorable safety profile, suggesting it may be advantageous in older patients at...
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells.
Nick Powell, Eirini Pantazi, Polychronis Pavlidis, Anastasia Tsakmaki, Katherine Li, Feifei Yang, Aimee Parker, Carmen Pin, Domenico Cozzetto, Danielle Minns, Emilie Stolarczyk, Svetlana Saveljeva, Rami Mohamed, Paul Lavender, Behdad Afzali, Jonathan Digby-Bell, Tsui Tjir-Li, Arthur Kaser, Joshua Friedman, Thomas T MacDonald, Gavin A Bewick, Graham M Lord
Dec 17, 2019
OBJECTIVE: The functional role of interleukin-22 (IL22) in chronic inflammation is controversial, and mechanistic insights into how it regulates target tissue are lacking. In this study, we evaluated the functional role of IL22...
ER stress Interleukin 22 inflammatory bowel disease Animals Anti-Bacterial Agents Apoptosis Cell Survival Chronic Disease Colitis Colon Crohn Disease Disease Models Animal Endoplasmic reticulum stress Epithelial Cells Gastrointestinal Agents Humans Interleukin-17 Interleukin-23 Interleukins Intestinal Mucosa Mice Organoids Patient acuity Phenylbutyrates Recombinant Proteins Transcription Genetic Tunicamycin Unfolded Protein Response Ustekinumab
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.
Edward J Needham, Alexander L Ren, Richard J Digby, Emma J Norton, Soraya Ebrahimi, Joanne G Outtrim, Doris A Chatfield, Anne E Manktelow, Maya M Leibowitz, Virginia FJ Newcombe, Rainer Doffinger, Gabriela Barcenas-Morales, Claudia Fonseca, Michael J Taussig, Rowan M Burnstein, Romit J Samanta, Cordelia Dunai, Nyarie Sithole, Nicholas J Ashton, Henrik Zetterberg, Magnus Gisslén, Arden Edén, Emelie Marklund, Peter JM Openshaw, Jake Dunning, Michael J Griffiths, Jonathan Cavanagh, Gerome Breen, Sarosh R Irani, Anne Elmer, Nathalie Kingston, Charlotte Summers, John R Bradley, Leonie S Taams, Benedict D Michael, Edward T Bullmore, Kenneth GC Smith, Paul A Lyons, Alasdair J Coles, David K Menon, Cambridge NeuroCOVID Group, CITIID-NIHR COVID-19 BioResource Collaboration, Cambridge NIHR Clinical Research Facility
Oct 06, 2022
COVID-19 is associated with neurological complications including stroke, delirium and encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms is common, and is seemingly unrelated to COVID-19...
Complete vertebrate mitogenomes reveal widespread repeats and gene duplications
Giulio Formenti, Arang Rhie, Jennifer Balacco, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, Samara Brown, Marco Rosario Capodiferro, Farooq O. Al-Ajli, Roberto Ambrosini, Peter Houde, Sergey Koren, Karen Oliver, Michelle Smith, Jason Skelton, Emma Betteridge, Jale Dolucan, Craig Corton, Iliana Bista, James Torrance, Alan Tracey, Jonathan Wood, Marcela Uliano-Silva, Kerstin Howe, Shane McCarthy, Sylke Winkler, Woori Kwak, Jonas Korlach, Arkarachai Fungtammasan, Daniel Fordham, Vania Costa, Simon Mayes, Matteo Chiara, David S. Horner, Eugene Myers, Richard Durbin, Alessandro Achilli, Edward L. Braun, Adam M. Phillippy, Erich D. Jarvis, Alexander N. G. Kirschel, Andrew Digby, Andrew Veale, Anne Bronikowski, Bob Murphy, Bruce Robertson, Clare Baker, Camila Mazzoni, Christopher Balakrishnan, Chul Lee, Daniel Mead, Emma Teeling, Erez Lieberman Aiden, Erica Todd, Evan Eichler, Gavin J. P. Naylor, Guojie Zhang, Jeramiah Smith, Jochen Wolf, Justin Touchon, Kira Delmore, Kjetill Jakobsen, Lisa Komoroske, Mark Wilkinson, Martin Genner, Martin Pšenička, Matthew Fuxjager, Mike Stratton, Miriam Liedvogel, Neil Gemmell, Piotr Minias, Peter O. Dunn, Peter Sudmant, Phil Morin, Qasim Ayub, Robert Kraus, Sonja Vernes, Steve Smith, Tanya Lama, Taylor Edwards, Tim Smith, Tom Gilbert, Tomas Marques-Bonet, Tony Einfeldt, Byrappa Venkatesh, Warren Johnson, Wes Warren, Yury Bukhman
Apr 29, 2021
Abstract: Background: Modern sequencing technologies should make the assembly of the relatively small mitochondrial genomes an easy undertaking. However, few tools exist that address mitochondrial assembly directly. Results: As...
Towards complete and error-free genome assemblies of all vertebrate species.
Arang Rhie, Shane A McCarthy, Olivier Fedrigo, Joana Damas, Giulio Formenti, Sergey Koren, Marcela Uliano-Silva, William Chow, Arkarachai Fungtammasan, Juwan Kim, Chul Lee, Byung June Ko, Mark Chaisson, Gregory L Gedman, Lindsey J Cantin, Francoise Thibaud-Nissen, Leanne Haggerty, Iliana Bista, Michelle Smith, Bettina Haase, Jacquelyn Mountcastle, Sylke Winkler, Sadye Paez, Jason Howard, Sonja C Vernes, Tanya M Lama, Frank Grutzner, Wesley C Warren, Christopher N Balakrishnan, Dave Burt, Julia M George, Matthew T Biegler, David Iorns, Andrew Digby, Daryl Eason, Bruce Robertson, Taylor Edwards, Mark Wilkinson, George Turner, Axel Meyer, Andreas F Kautt, Paolo Franchini, H William Detrich, Hannes Svardal, Maximilian Wagner, Gavin JP Naylor, Martin Pippel, Milan Malinsky, Mark Mooney, Maria Simbirsky, Brett T Hannigan, Trevor Pesout, Marlys Houck, Ann Misuraca, Sarah B Kingan, Richard Hall, Zev Kronenberg, Ivan Sović, Christopher Dunn, Zemin Ning, Alex Hastie, Joyce Lee, Siddarth Selvaraj, Richard E Green, Nicholas H Putnam, Ivo Gut, Jay Ghurye, Erik Garrison, Ying Sims, Joanna Collins, Sarah Pelan, James Torrance, Alan Tracey, Jonathan Wood, Robel E Dagnew, Dengfeng Guan, Sarah E London, David F Clayton, Claudio V Mello, Samantha R Friedrich, Peter V Lovell, Ekaterina Osipova, Farooq O Al-Ajli, Simona Secomandi, Heebal Kim, Constantina Theofanopoulou, Michael Hiller, Yang Zhou, Robert S Harris, Kateryna D Makova, Paul Medvedev, Jinna Hoffman, Patrick Masterson, Karen Clark, Fergal Martin, Kevin Howe, Paul Flicek, Brian P Walenz, Woori Kwak, Hiram Clawson, Mark Diekhans, Luis Nassar, Benedict Paten, Robert HS Kraus, Andrew J Crawford, M Thomas P Gilbert, Guojie Zhang, Byrappa Venkatesh, Robert W Murphy, Klaus-Peter Koepfli, Beth Shapiro, Warren E Johnson, Federica Di Palma, Tomas Marques-Bonet, Emma C Teeling, Tandy Warnow, Jennifer Marshall Graves, Oliver A Ryder, David Haussler, Stephen J O'Brien, Jonas Korlach, Harris A Lewin, Kerstin Howe, Eugene W Myers, Richard Durbin, Adam M Phillippy, Erich D Jarvis
Jul 05, 2021
High-quality and complete reference genome assemblies are fundamental for the application of genomics to biology, disease, and biodiversity conservation. However, such assemblies are available for only a few non-microbial...
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