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Results: 1610
Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality
BACKGROUND: Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status...
The International Human Epigenome Consortium
The International Human Epigenome Consortium (IHEC) coordinates the generation of a catalog of high-resolution reference epigenomes of major primary human cell types. The studies now presented (see the Cell Press IHEC web portal...
Changes in waist circumference and risk of all-cause and CVD mortality
Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Nicholas J. Wareham, Kay-Tee Khaw
Oct 27, 2020
Abstract: Background: Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data are limited and conflicting regarding the consequences of changes in body fat...
Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population
Abstract
Background
Despite convincing evidence in the Mediterranean region, the cardiovascular benefit of the Mediterranean diet is not well established in non-Mediterranean...
Validation of the Systematic COronary Risk Evaluation - Older Persons (SCORE-OP) in the EPIC-Norfolk prospective population study.
Lotte Verweij, Ron Jg Peters, Wilma JM Scholte Op Reimer, S Matthijs Boekholdt, Robert M Luben, Nicholas J Wareham, Kay-Tee Khaw, Corine HM Latour, Harald T Jorstad
Aug 29, 2019
BACKGROUND: The Systematic COronary Risk Evaluation - Older Persons (SCORE-OP) algorithm is developed to assess 10-year risk of death due to cardiovascular disease (CVD) in individuals aged ≥65 years. We studied the performance...
Gene Ontology Consortium
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe...
ImmUniverse Consortium
Stefania Vetrano, Gerben Bouma, Robert J Benschop, Thomas Birngruber, Antonio Costanzo, GRAM D'Haens, Loredana Frasca, Rainer Hillenbrand, Lars Iversen, Claus Johansen, Arthur Kaser, Hans JPM Koenen, Christa Noehammer, Laurent Peyrin-Biroulet, Jeroen Raes, Leonardo Ricotti, Philip Rosenstiel, Venkata P Satagopam, Stefan Schreiber, Severine Vermeire, Andreas Wollenberg, Stephan Weidinger, Daniel Ziemek, Silvio Danese, ImmUniverse Consortium
Jan 04, 2023
Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating, multifactorial and unrelated conditions featured by a dysregulated immune response leading to destructive chronic inflammation. The immune...
Plasma trimethylamine N-oxide (TMAO) levels predict future risk of coronary artery disease in apparently healthy individuals in the EPIC-Norfolk prospective population study.
WH Wilson Tang, Xinmin S Li, Yuping Wu, Zeneng Wang, Kay-Tee Khaw, Nicholas J Wareham, Max Nieuwdorp, S Matthijs Boekholdt, Stanley L Hazen
Mar 01, 2021
BACKGROUND: Recent studies show a mechanistic link between gut microbiota-dependent formation of the atherosclerosis- and thrombosis-promoting metabolite trimethylamine N-oxide (TMAO) and cardiovascular disease (CVD). The...
Milk intake and incident stroke and CHD in populations of European descent
LET Vissers, I Sluijs, S Burgess, NG Forouhi, H Freisling, F Imamura, TK Nilsson, F Renström, E Weiderpass, K Aleksandrova, CC Dahm, A Perez-Cornago, MB Schulze, TYN Tong, D Aune, C Bonet, JMA Boer, H Boeing, MD Chirlaque, MI Conchi, L Imaz, S Jäger, V Krogh, C Kyrø, G Masala, O Melander, K Overvad, S Panico, MJ Sánches, E Sonestedt, A Tjønneland, I Tzoulaki, WMM Verschuren, E Riboli, NJ Wareham, J Danesh, AS Butterworth, YT van der Schouw
Oct 28, 2021
Higher milk intake has been associated with a lower stroke risk, but not with risk of CHD. Residual confounding or reverse causation cannot be excluded. Therefore, we estimated the causal association of milk consumption with...
Impact of physical activity on the risk of cardiovascular disease in middle-aged and older adults
Sangeeta Lachman, S Matthijs Boekholdt, Robert N Luben, Stephen J Sharp, Soren Brage, Kay-Tee Khaw, Ron Jg Peters, Nicholas J Wareham
Feb 12, 2018
Background There is broad consensus that regular physical activity yields major health benefits. However, current guidelines on physical activity are mainly aimed at middle-aged adults. It is unclear whether physical activity...
physical activity cardiovascular disease elderly people middle-aged adults Adult Age Factors Aged Cardiovascular Diseases England Exercise Female health status healthy aging Healthy lifestyle Humans Male Middle Aged Prognosis Prospective Studies Protective factors Risk Factors Risk Reduction Behavior Time Factors
Long Term Prognostic Impact of Sex-specific Longitudinal Changes in Blood Pressure. The EPIC-Norfolk Prospective Population Cohort Study.
Tiberiu A Pana, Robert N Luben, Mamas A Mamas, John F Potter, Nicholas J Wareham, Kay-Tee Khaw, Phyo K Myint
Jul 12, 2021
AIMS: We aimed to determine the sex differences in longitudinal systolic and diastolic blood pressure (SBP and DBP) trajectories in mid-life and delineate the associations between these and mortality (all-cause, cardiovascular...
Harmonising electronic health records for reproducible research
Hoda Abbasizanjani, Fatemeh Torabi, Stuart Bedston, Thomas Bolton, Gareth Davies, Spiros Denaxas, Rowena Griffiths, Laura Herbert, Sam Hollings, Spencer Keene, Kamlesh Khunti, Emily Lowthian, Jane Lyons, Mehrdad A Mizani, John Nolan, Cathie Sudlow, Venexia Walker, William Whiteley, Angela Wood, Ashley Akbari, CVD-COVID-UK/COVID-IMPACT Consortium
Jan 16, 2023
BACKGROUND: The CVD-COVID-UK consortium was formed to understand the relationship between COVID-19 and cardiovascular diseases through analyses of harmonised electronic health records (EHRs) across the four UK nations. Beyond...
Harmonising electronic health records for reproducible research
Hoda Abbasizanjani, Fatemeh Torabi, Stuart Bedston, Thomas Bolton, Gareth Davies, Spiros Denaxas, Rowena Griffiths, Laura Herbert, Sam Hollings, Spencer Keene, Kamlesh Khunti, Emily Lowthian, Jane Lyons, Mehrdad A Mizani, John Nolan, Cathie Sudlow, Venexia Walker, William Whiteley, Angela Wood, Ashley Akbari, CVD-COVID-UK/COVID-IMPACT Consortium
Feb 17, 2023
BACKGROUND: The CVD-COVID-UK consortium was formed to understand the relationship between COVID-19 and cardiovascular diseases through analyses of harmonised electronic health records (EHRs) across the four UK nations. Beyond...
Epic Aspects of Retail Encounters:
Much has been written about myth and the marketplace. Consumer research has added immeasurably to academics’ appreciation of the myths that inhere in fabulous flagship stores and experiential retailing more generally. Studies of...
The SPECTRUM Consortium
M Horton, PR Perman-Howe, C Angus, J Bishop, I Bogdanovica, A Brennan, J Britton, LS Brose, J Brown, J Collin, M Dockrell, N Fitzgerald, S Friel, D Gillespie, AB Gilmore, SE Hill, C Knai, T Langley, S Martin, A McNeill, G Moore, MR Munafò, RL Murray, M Opazo Breton, J Pearce, M Petticrew, G Reid, D Robson, H Rutter, L Shahab, N Shortt, K Smith, K Syrett, L Bauld
Dec 31, 2021
The main causes of non-communicable diseases (NCDs), health inequalities and health inequity include consumption of unhealthy commodities such as tobacco, alcohol and/or foods high in fat, salt and/or sugar. These exposures...
The SPECTRUM Consortium
M Horton, PR Perman-Howe, C Angus, J Bishop, I Bogdanovica, A Brennan, J Britton, LS Brose, J Brown, J Collin, M Dockrell, N Fitzgerald, S Friel, D Gillespie, AB Gilmore, SE Hill, C Knai, T Langley, S Martin, A McNeill, G Moore, MR Munafò, RL Murray, M Opazo Breton, J Pearce, M Petticrew, G Reid, D Robson, H Rutter, L Shahab, N Shortt, K Smith, K Syrett, L Bauld
Dec 31, 2021
The main causes of non-communicable diseases (NCDs), health inequalities and health inequity include consumption of unhealthy commodities such as tobacco, alcohol and/or foods high in fat, salt and/or sugar. These exposures...
Dietary fibre and incidence of type 2 diabetes in eight European countries
InterAct Consortium
Jan 23, 2018
AIMS/HYPOTHESIS: Intake of dietary fibre has been associated with a reduced risk of type 2 diabetes, but few European studies have been published on this. We evaluated the association between intake of dietary fibre and type 2...
Investigation of gene-diet interactions in the incretin system and risk of type 2 diabetes
InterAct Consortium
Sep 06, 2019
AIMS/HYPOTHESIS: The gut incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) have a major role in the pathophysiology of type 2 diabetes. Specific genetic and dietary factors have...
Coffee dairy Fibre GIPR Gene–environment interaction Incretins KCNQ1 Olive Oil TCF7L2 WFS1 Alleles Case-Control Studies Coffee Diabetes mellitus Type 2 Diet Dietary Fiber Female Gastric Inhibitory Polypeptide Humans Incretins KCNQ1 Potassium Channel Male Membrane Proteins Middle Aged Olive Oil Proportional Hazards Models Transcription Factor 7-Like 2 Protein
Epic Aspects of Retail Encounters:
Much has been written about myth and the marketplace. Consumer research has added immeasurably to academics’ appreciation of the myths that inhere in fabulous flagship stores and experiential retailing more generally. Studies of...
Stability Analysis of EPC Consortium Cooperation Based on Evolutionary Game
Consortium contracting is a contracting model that China encourages and advocates. Due to the interest drive, members within the consortium are very prone to negative cooperation and midway withdrawal, which hinders the healthy...
Published by: IGI Global Scientific Publishing
The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs
Typhoid fever is estimated to cause between 11.9-26.9 million infections globally each year with 129,000-216,510 deaths. Access to improved water sources have reduced disease incidence in parts of the world but the use of...
Biomarker-estimated flavan-3-ol intake is associated with lower blood pressure in cross-sectional analysis in EPIC Norfolk.
Javier I Ottaviani, Abigail Britten, Debora Lucarelli, Robert Luben, Angela A Mulligan, Marleen A Lentjes, Reedmond Fong, Nicola Gray, Philip B Grace, Deborah H Mawson, Amy Tym, Antonia Wierzbicki, Nita G Forouhi, Kay-Tee Khaw, Hagen Schroeter, Gunter GC Kuhnle
Nov 12, 2020
Flavan-3-ols are a group of bioactive compounds that have been shown to improve vascular function in intervention studies. They are therefore of great interest for the development of dietary recommendation for the prevention of...
Proposing a Library Consortium Model for National Development in Zimbabwe
Collence Chisita
Jul 01, 2021
Globally library cooperation and collaboration is transforming the scholarship landscape as academic libraries battle to survive amidst escalating costs of subscriptions. Zimbabwe is no exception to this phenomenon as evidenced...
Published by: IGI Global Scientific Publishing
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