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Paying Lip Service?
Literature has mainly analyzed the technical attributes of voice for enterprise technical applications, such as voice signature and speech recognition. This paper aims at identifying voice and speech attributes that reflect...
Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women.
Our study describes breast cancer risk loci using a cross-ancestry GWAS approach. We first identify variants that are associated with breast cancer at P < 0.05 from African ancestry GWAS meta-analysis (9241 cases and 10193...
Published by: Nature Communications
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Jingjing Liu, Wendy JC Prager-Van der Smissen, J Margriet Collée, Manjeet K Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Thomas U Ahearn, Kristiina Aittomäki, Christine B Ambrosone, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Norbert Arnold, Kristan J Aronson, Annelie Augustinsson, Päivi Auvinen, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Marina Bermisheva, Leslie Bernstein, Natalia V Bogdanova, Nadja Bogdanova-Markov, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Sara Y Brucker, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Hui Cai, Daniele Campa, Federico Canzian, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Ji-Yeob Choi, Melissa Christiaens, Christine L Clarke, NBCS Collaborators, Fergus J Couch, Kamila Czene, Mary B Daly, Peter Devilee, Isabel dos-Santos-Silva, Miriam Dwek, Diana M Eccles, A Heather Eliassen, Peter A Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Susan M Gapstur, Montserrat García-Closas, José A García-Sáenz, Mia M Gaudet, Graham G Giles, Mark S Goldberg, David E Goldgar, Pascal Guénel, Christopher A Haiman, Niclas Håkansson, Per Hall, Patricia A Harrington, Steven N Hart, Mikael Hartman, Peter Hillemanns, John L Hopper, Ming-Feng Hou, David J Hunter, Dezheng Huo, ABCTB Investigators, Hidemi Ito, Motoki Iwasaki, Milena Jakimovska, Anna Jakubowska, Esther M John, Rudolf Kaaks, Daehee Kang, Renske Keeman, Elza Khusnutdinova, Sung-Won Kim, Peter Kraft, Vessela N Kristensen, Allison W Kurian, Loic Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Robert N Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L Milne, Kenneth Muir, Anna Marie Mulligan, Susan L Neuhausen, Heli Nevanlinna, Kenneth Offit, Olufunmilayo I Olopade, Janet E Olson, Håkan Olsson, Nick Orr, Sue K Park, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Rohini Rau-Murthy, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Rita K Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Christof Sohn, Melissa C Southey, John J Spinelli, Rulla M Tamimi, William J Tapper, Soo H Teo, Mary Beth Terry, Diana Torres, Thérèse Truong, Michael Untch, Celine M Vachon, Christi J van Asperen, Alicja Wolk, Taiki Yamaji, Wei Zheng, Argyrios Ziogas, Elad Ziv, Gabriela Torres-Mejía, Thilo Dörk, Anthony J Swerdlow, Ute Hamann, Marjanka K Schmidt, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, Maartje J Hooning, John WM Martens, Antoinette Hollestelle
May 13, 2020
In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a prostate...
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Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Jingjing Liu, Wendy J. C. Prager - van der Smissen, J. Margriet Collée, Manjeet K. Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Thomas U. Ahearn, Kristiina Aittomäki, Christine B. Ambrosone, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Norbert Arnold, Kristan J. Aronson, Annelie Augustinsson, Päivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Leslie Bernstein, Natalia V. Bogdanova, Nadja Bogdanova-Markov, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Sara Y. Brucker, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Hui Cai, Daniele Campa, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Melissa Christiaens, Christine L. Clarke, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Isabel dos-Santos-Silva, Miriam Dwek, Diana M. Eccles, A. Heather Eliassen, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, David E. Goldgar, Pascal Guénel, Christopher A. Haiman, Niclas Håkansson, Per Hall, Patricia A. Harrington, Steven N. Hart, Mikael Hartman, Peter Hillemanns, John L. Hopper, Ming-Feng Hou, David J. Hunter, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Milena Jakimovska, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Daehee Kang, Renske Keeman, Elza Khusnutdinova, Sung-Won Kim, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Loic Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Robert N. Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L. Milne, Kenneth Muir, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, Kenneth Offit, Olufunmilayo I. Olopade, Janet E. Olson, Håkan Olsson, Nick Orr, Sue K. Park, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Rohini Rau-Murthy, Gad Rennert, Hedy S. Rennert, Valerie Rhenius, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Rita K. Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Christof Sohn, Melissa C. Southey, John J. Spinelli, Rulla M. Tamimi, William J. Tapper, Soo H. Teo, Mary Beth Terry, Diana Torres, Thérèse Truong, Michael Untch, Celine M. Vachon, Christi J. van Asperen, Alicja Wolk, Taiki Yamaji, Wei Zheng, Argyrios Ziogas, Elad Ziv, Gabriela Torres-Mejía, Thilo Dörk, Anthony J. Swerdlow, Ute Hamann, Marjanka K. Schmidt, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, Maartje J. Hooning, John W. M. Martens, Antoinette Hollestelle, Kristine K. Sahlberg, Anne-Lise Børresen-Dale, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, Grethe I. Grenaker Alnæs, Tone F. Bathen, Elin Borgen, Britt Fritzman, Øystein Garred, Gry Aarum Geitvik, Solveig Hofvind, Anita Langerød, Ole Christian Lingjaerde, Gunhild Mari Mælandsmo, Hege G Russnes, Helle Kristine Skjerven, Therese Sørlie, Christine Clarke, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, Peter Simpson, Dinny Graham, Mythily Sachchithananthan
Jun 17, 2021
Abstract: In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a...
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A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
Lang Wu, Wei Shi, Jirong Long, Xingyi Guo, Kyriaki Michailidou, Jonathan Beesley, Manjeet K Bolla, Xiao-Ou Shu, Yingchang Lu, Qiuyin Cai, Fares Al-Ejeh, Esdy Rozali, Qin Wang, Joe Dennis, Bingshan Li, Chenjie Zeng, Helian Feng, Alexander Gusev, Richard T Barfield, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Paul L Auer, Myrto Barrdahl, Caroline Baynes, Matthias W Beckmann, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Louise Brinton, Per Broberg, Sara Y Brucker, Barbara Burwinkel, Trinidad Caldés, Federico Canzian, Brian D Carter, J Esteban Castelao, Jenny Chang-Claude, Xiaoqing Chen, Ting-Yuan David Cheng, Hans Christiansen, Christine L Clarke, NBCS Collaborators, Margriet Collée, Sten Cornelissen, Fergus J Couch, David Cox, Angela Cox, Simon S Cross, Julie M Cunningham, Kamila Czene, Mary B Daly, Peter Devilee, Kimberly F Doheny, Thilo Dörk, Isabel dos-Santos-Silva, Martine Dumont, Miriam Dwek, Diana M Eccles, Ursula Eilber, A Heather Eliassen, Christoph Engel, Mikael Eriksson, Laura Fachal, Peter A Fasching, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Henrik Flyger, Lin Fritschi, Marike Gabrielson, Manuela Gago-Dominguez, Susan M Gapstur, Montserrat García-Closas, Mia M Gaudet, Maya Ghoussaini, Graham G Giles, Mark S Goldberg, David E Goldgar, Anna González-Neira, Pascal Guénel, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Emily Hallberg, Ute Hamann, Patricia Harrington, Alexander Hein, Belynda Hicks, Peter Hillemanns, Antoinette Hollestelle, Robert N Hoover, John L Hopper, Guanmengqian Huang, Keith Humphreys, David J Hunter, Anna Jakubowska, Wolfgang Janni, Esther M John, Nichola Johnson, Kristine Jones, Michael E Jones, Audrey Jung, Rudolf Kaaks, Michael J Kerin, Elza Khusnutdinova, Veli-Matti Kosma, Vessela N Kristensen, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Sara Lindström, Jolanta Lissowska, Wing-Yee Lo, Sibylle Loibl, Jan Lubinski, Craig Luccarini, Michael P Lux, Robert J Macinnis, Tom Maishman, Ivana Maleva Kostovska, Arto Mannermaa, JoAnn E Manson, Sara Margolin, Dimitrios Mavroudis, Hanne Meijers-Heijboer, Alfons Meindl, Usha Menon, Jeffery Meyer, Anna Marie Mulligan, Susan L Neuhausen, Heli Nevanlinna, Patrick Neven, Sune F Nielsen, Børge G Nordestgaard, Olufunmilayo I Olopade, Janet E Olson, Håkan Olsson, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Ross Prentice, Nadege Presneau, Katri Pylkäs, Brigitte Rack, Paolo Radice, Nazneen Rahman, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Jane Romm, Anja Rudolph, Emmanouil Saloustros, Dale P Sandler, Elinor J Sawyer, Marjanka K Schmidt, Rita K Schmutzler, Andreas Schneeweiss, Rodney J Scott, Christopher G Scott, Sheila Seal, Mitul Shah, Martha J Shrubsole, Ann Smeets, Melissa C Southey, John J Spinelli, Jennifer Stone, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, William Tapper, Jack A Taylor, Mary Beth Terry, Daniel C Tessier, Abigail Thomas, Kathrin Thöne, Rob AEM Tollenaar, Diana Torres, Thérèse Truong, Michael Untch, Celine Vachon, David Van Den Berg, Daniel Vincent, Quinten Waisfisz, Clarice R Weinberg, Camilla Wendt, Alice S Whittemore, Hans Wildiers, Walter C Willett, Robert Winqvist, Alicja Wolk, Lucy Xia, Xiaohong R Yang, Argyrios Ziogas, Elad Ziv, kConFab/AOCS Investigators, Alison M Dunning, Paul DP Pharoah, Jacques Simard, Roger L Milne, Stacey L Edwards, Peter Kraft, Douglas F Easton, Georgia Chenevix-Trench, Wei Zheng
Jul 31, 2018
The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes responsible for these associations remain largely unknown. To identify...
Published by:
Two truncating variants in FANCC and breast cancer risk.
Thilo Dörk, Paolo Peterlongo, Arto Mannermaa, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Laura E Beane Freeman, Matthias W Beckmann, Alicia Beeghly-Fadiel, Sabine Behrens, Marina Bermisheva, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Federico Canzian, Tsun L Chan, Jenny Chang-Claude, Stephen J Chanock, Ji-Yeob Choi, Hans Christiansen, Christine L Clarke, Fergus J Couch, Kamila Czene, Mary B Daly, Isabel dos-Santos-Silva, Miriam Dwek, Diana M Eccles, Arif B Ekici, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Marike Gabrielson, Manuela Gago-Dominguez, Chi Gao, Susan M Gapstur, Montserrat García-Closas, José A García-Sáenz, Mia M Gaudet, Graham G Giles, Mark S Goldberg, David E Goldgar, Pascal Guénel, Lothar Haeberle, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Mikael Hartman, Jan Hauke, Alexander Hein, Peter Hillemanns, Frans BL Hogervorst, Maartje J Hooning, John L Hopper, Tony Howell, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M John, Audrey Jung, Rudolf Kaaks, Daehee Kang, Pooja Middha Kapoor, Elza Khusnutdinova, Sung-Won Kim, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, Ava Kwong, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Sara Lindström, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Jan Lubiński, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Elena Martinez, Keitaro Matsuo, Dimitris Mavroudis, Alfons Meindl, Usha Menon, Roger L Milne, Nur Aishah Mohd Taib, Kenneth Muir, Anna Marie Mulligan, Susan L Neuhausen, Heli Nevanlinna, Patrick Neven, William G Newman, Kenneth Offit, Olufunmilayo I Olopade, Andrew F Olshan, Janet E Olson, Håkan Olsson, Sue K Park, Tjoung-Won Park-Simon, Julian Peto, Dijana Plaseska-Karanfilska, Esther Pohl-Rescigno, Nadege Presneau, Brigitte Rack, Paolo Radice, Muhammad U Rashid, Gad Rennert, Hedy S Rennert, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Marjanka K Schmidt, Rita K Schmutzler, Michael O Schneider, Minouk J Schoemaker, Christopher Scott, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Susan Slager, Snezhana Smichkoska, Melissa C Southey, John J Spinelli, Jennifer Stone, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, William J Tapper, Soo H Teo, Mary Beth Terry, Amanda E Toland, Rob AEM Tollenaar, Diana Torres, Gabriela Torres-Mejía, Melissa A Troester, Thérèse Truong, Shoichiro Tsugane, Michael Untch, Celine M Vachon, Ans MW van den Ouweland, Elke M van Veen, Joseph Vijai, Camilla Wendt, Alicja Wolk, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, ABCTB Investigators, NBCS Collaborators, Alison M Dunning, Paul DP Pharoah, Detlev Schindler, Peter Devilee, Douglas F Easton
Sep 09, 2019
Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer risk, while the risk...
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Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry
Stefanie H Mueller, Alvina G Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Thais Baert, Laura E Beane Freeman, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Bernardo Bonanni, Hermann Brenner, Sara Y Brucker, Saundra S Buys, Jose E Castelao, Tsun L Chan, Jenny Chang-Claude, Stephen J Chanock, Ji-Yeob Choi, Wendy K Chung, Kristine K Sahlberg, Anne-Lise Børresen-Dale, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E Kiserud, Kristin V Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, Grethe I Grenaker Alnæs, Sarah V Colonna, Sten Cornelissen, Fergus J Couch, Kamila Czene, Mary B Daly, Peter Devilee, Thilo Dörk, Laure Dossus, Miriam Dwek, Diana M Eccles, Arif B Ekici, A Heather Eliassen, Christoph Engel, D Gareth Evans, Peter A Fasching, Olivia Fletcher, Henrik Flyger, Manuela Gago-Dominguez, Yu-Tang Gao, Montserrat García-Closas, José A García-Sáenz, Jeanine Genkinger, Aleksandra Gentry-Maharaj, Felix Grassmann, Pascal Guénel, Melanie Gündert, Lothar Haeberle, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Elaine F Harkness, Patricia A Harrington, Jaana M Hartikainen, Mikael Hartman, Alexander Hein, Weang-Kee Ho, Maartje J Hooning, Reiner Hoppe, John L Hopper, Richard S Houlston, Anthony Howell, David J Hunter, Dezheng Huo, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, Peter Simpson, Dinny Graham, Mythily Sachchithananthan, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M John, Michael E Jones, Audrey Jung, Rudolf Kaaks, Daehee Kang, Elza K Khusnutdinova, Sung-Won Kim, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, Katerina Kubelka-Sabit, Allison W Kurian, Ava Kwong, James V Lacey, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Keitaro Matsuo, Dimitrios Mavroudis, Usha Menon, Kenneth Muir, Rachel A Murphy, Heli Nevanlinna, William G Newman, Dieter Niederacher, Katie M O’Brien, Nadia Obi, Kenneth Offit, Olufunmilayo I Olopade, Andrew F Olshan, Håkan Olsson, Sue K Park, Alpa V Patel, Achal Patel, Charles M Perou, Julian Peto, Paul DP Pharoah, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Paolo Radice, Dhanya Ramachandran, Muhammad U Rashid, Gad Rennert, Atocha Romero, Kathryn J Ruddy, Matthias Ruebner, Emmanouil Saloustros, Dale P Sandler, Elinor J Sawyer, Marjanka K Schmidt, Rita K Schmutzler, Michael O Schneider, Christopher Scott, Mitul Shah, Priyanka Sharma, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Harald Surowy, Rulla M Tamimi, William J Tapper, Jack A Taylor, Soo Hwang Teo, Lauren R Teras, Amanda E Toland, Rob AEM Tollenaar, Diana Torres, Gabriela Torres-Mejía, Melissa A Troester, Thérèse Truong, Celine M Vachon, Joseph Vijai, Clarice R Weinberg, Camilla Wendt, Robert Winqvist, Alicja Wolk, Anna H Wu, Taiki Yamaji, Xiaohong R Yang, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, Alison M Dunning, Douglas F Easton, Harry Hemingway, Ute Hamann, Karoline B Kuchenbaecker
Jan 26, 2023
Abstract Background Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can...
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Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Jingjing Liu, Wendy J. C. Prager - van der Smissen, J. Margriet Collée, Manjeet K. Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Thomas U. Ahearn, Kristiina Aittomäki, Christine B. Ambrosone, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Norbert Arnold, Kristan J. Aronson, Annelie Augustinsson, Päivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Leslie Bernstein, Natalia V. Bogdanova, Nadja Bogdanova-Markov, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Sara Y. Brucker, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Hui Cai, Daniele Campa, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Melissa Christiaens, Christine L. Clarke, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Isabel dos-Santos-Silva, Miriam Dwek, Diana M. Eccles, A. Heather Eliassen, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, David E. Goldgar, Pascal Guénel, Christopher A. Haiman, Niclas Håkansson, Per Hall, Patricia A. Harrington, Steven N. Hart, Mikael Hartman, Peter Hillemanns, John L. Hopper, Ming-Feng Hou, David J. Hunter, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Milena Jakimovska, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Daehee Kang, Renske Keeman, Elza Khusnutdinova, Sung-Won Kim, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Loic Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Robert N. Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L. Milne, Kenneth Muir, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, Kenneth Offit, Olufunmilayo I. Olopade, Janet E. Olson, Håkan Olsson, Nick Orr, Sue K. Park, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Rohini Rau-Murthy, Gad Rennert, Hedy S. Rennert, Valerie Rhenius, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Rita K. Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Christof Sohn, Melissa C. Southey, John J. Spinelli, Rulla M. Tamimi, William J. Tapper, Soo H. Teo, Mary Beth Terry, Diana Torres, Thérèse Truong, Michael Untch, Celine M. Vachon, Christi J. van Asperen, Alicja Wolk, Taiki Yamaji, Wei Zheng, Argyrios Ziogas, Elad Ziv, Gabriela Torres-Mejía, Thilo Dörk, Anthony J. Swerdlow, Ute Hamann, Marjanka K. Schmidt, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, Maartje J. Hooning, John W. M. Martens, Antoinette Hollestelle, Kristine K. Sahlberg, Anne-Lise Børresen-Dale, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, Grethe I. Grenaker Alnæs, Tone F. Bathen, Elin Borgen, Britt Fritzman, Øystein Garred, Gry Aarum Geitvik, Solveig Hofvind, Anita Langerød, Ole Christian Lingjaerde, Gunhild Mari Mælandsmo, Hege G Russnes, Helle Kristine Skjerven, Therese Sørlie, Christine Clarke, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, Peter Simpson, Dinny Graham, Mythily Sachchithananthan
Jun 16, 2020
Abstract: In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a...
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Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
Stefanie H Mueller, Alvina G Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Thais Baert, Laura E Beane Freeman, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Bernardo Bonanni, Hermann Brenner, Sara Y Brucker, Saundra S Buys, Jose E Castelao, Tsun L Chan, Jenny Chang-Claude, Stephen J Chanock, Ji-Yeob Choi, Wendy K Chung, NBCS Collaborators, Sarah V Colonna, CTS Consortium, Sten Cornelissen, Fergus J Couch, Kamila Czene, Mary B Daly, Peter Devilee, Thilo Dörk, Laure Dossus, Miriam Dwek, Diana M Eccles, Arif B Ekici, A Heather Eliassen, Christoph Engel, D Gareth Evans, Peter A Fasching, Olivia Fletcher, Henrik Flyger, Manuela Gago-Dominguez, Yu-Tang Gao, Montserrat García-Closas, José A García-Sáenz, Jeanine Genkinger, Aleksandra Gentry-Maharaj, Felix Grassmann, Pascal Guénel, Melanie Gündert, Lothar Haeberle, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Elaine F Harkness, Patricia A Harrington, Jaana M Hartikainen, Mikael Hartman, Alexander Hein, Weang-Kee Ho, Maartje J Hooning, Reiner Hoppe, John L Hopper, Richard S Houlston, Anthony Howell, David J Hunter, Dezheng Huo, ABCTB Investigators, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M John, Michael E Jones, Audrey Jung, Rudolf Kaaks, Daehee Kang, Elza K Khusnutdinova, Sung-Won Kim, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, Katerina Kubelka-Sabit, Allison W Kurian, Ava Kwong, James V Lacey, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Keitaro Matsuo, Dimitrios Mavroudis, Usha Menon, Kenneth Muir, Rachel A Murphy, Heli Nevanlinna, William G Newman, Dieter Niederacher, Katie M O'Brien, Nadia Obi, Kenneth Offit, Olufunmilayo I Olopade, Andrew F Olshan, Håkan Olsson, Sue K Park, Alpa V Patel, Achal Patel, Charles M Perou, Julian Peto, Paul DP Pharoah, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Paolo Radice, Dhanya Ramachandran, Muhammad U Rashid, Gad Rennert, Atocha Romero, Kathryn J Ruddy, Matthias Ruebner, Emmanouil Saloustros, Dale P Sandler, Elinor J Sawyer, Marjanka K Schmidt, Rita K Schmutzler, Michael O Schneider, Christopher Scott, Mitul Shah, Priyanka Sharma, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Harald Surowy, Rulla M Tamimi, William J Tapper, Jack A Taylor, Soo Hwang Teo, Lauren R Teras, Amanda E Toland, Rob AEM Tollenaar, Diana Torres, Gabriela Torres-Mejía, Melissa A Troester, Thérèse Truong, Celine M Vachon, Joseph Vijai, Clarice R Weinberg, Camilla Wendt, Robert Winqvist, Alicja Wolk, Anna H Wu, Taiki Yamaji, Xiaohong R Yang, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, Alison M Dunning, Douglas F Easton, Harry Hemingway, Ute Hamann, Karoline B Kuchenbaecker
Feb 26, 2023
BACKGROUND: Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes. METHODS: We...
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Two truncating variants in FANCC and breast cancer risk
Thilo Dörk, Paolo Peterlongo, Arto Mannermaa, Manjeet K. Bolla, Qin Wang, Joe Dennis, Thomas Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Laura E. Beane Freeman, Matthias W. Beckmann, Alicia Beeghly-Fadiel, Sabine Behrens, Marina Bermisheva, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Federico Canzian, Tsun L. Chan, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Hans Christiansen, Christine L. Clarke, Fergus J. Couch, Kamila Czene, Mary B. Daly, Isabel dos-Santos-Silva, Miriam Dwek, Diana M. Eccles, Arif B. Ekici, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Marike Gabrielson, Manuela Gago-Dominguez, Chi Gao, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, David E. Goldgar, Pascal Guénel, Lothar Haeberle, Christopher A. Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Mikael Hartman, Jan Hauke, Alexander Hein, Peter Hillemanns, Frans B. L. Hogervorst, Maartje J. Hooning, John L. Hopper, Tony Howell, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M. John, Audrey Jung, Rudolf Kaaks, Daehee Kang, Pooja Middha Kapoor, Elza Khusnutdinova, Sung-Won Kim, Cari M. Kitahara, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Ava Kwong, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Sara Lindström, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Jan Lubiński, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Elena Martinez, Keitaro Matsuo, Dimitris Mavroudis, Alfons Meindl, Usha Menon, Roger L. Milne, Nur Aishah Mohd Taib, Kenneth Muir, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, Patrick Neven, William G. Newman, Kenneth Offit, Olufunmilayo I. Olopade, Andrew F. Olshan, Janet E. Olson, Håkan Olsson, Sue K. Park, Tjoung-Won Park-Simon, Julian Peto, Dijana Plaseska-Karanfilska, Esther Pohl-Rescigno, Nadege Presneau, Brigitte Rack, Paolo Radice, Muhammad U. Rashid, Gad Rennert, Hedy S. Rennert, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Marjanka K. Schmidt, Rita K. Schmutzler, Michael O. Schneider, Minouk J. Schoemaker, Christopher Scott, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Susan Slager, Snezhana Smichkoska, Melissa C. Southey, John J. Spinelli, Jennifer Stone, Harald Surowy, Anthony J. Swerdlow, Rulla M. Tamimi, William J. Tapper, Soo H. Teo, Mary Beth Terry, Amanda E. Toland, Rob A. E. M. Tollenaar, Diana Torres, Gabriela Torres-Mejía, Melissa A. Troester, Thérèse Truong, Shoichiro Tsugane, Michael Untch, Celine M. Vachon, Ans M. W. van den Ouweland, Elke M. van Veen, Joseph Vijai, Camilla Wendt, Alicja Wolk, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, Alison M. Dunning, Paul D. P. Pharoah, Detlev Schindler, Peter Devilee, Douglas F. Easton, Rosemary Balleine, Robert Baxter, Stephen Braye, Jane Carpenter, Jane Dahlstrom, John Forbes, C. Soon Lee, Deborah Marsh, Adrienne Morey, Nirmala Pathmanathan, Rodney Scott, Peter Simpson, Allan Spigelman, Nicholas Wilcken, Desmond Yip, Nikolajs Zeps, Anne-Lise Børresen-Dale, Grethe I. Grenaker Alnæs, Kristine K. Sahlberg, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler
Aug 28, 2020
Abstract: Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer risk, while the...
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