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New perspectives in eosinophilic granulomatosis with polyangiitis (EGPA)
Chiara Marvisi, Renato Alberto Sinico, Carlo Salvarani, David Jayne, Domenico Prisco, Benjamin Terrier, Giacomo Emmi, Augusto Vaglio, European EGPA Study Group
May 27, 2020
The European Eosinophilic Granulomatosis with Polyangiitis (EGPA) study group first gathered in Firenze in December 2018. The discussion was centred around the clinical and therapeutic needs in EGPA which still remain unmet....
Towards standard electrolytes for sodium-ion batteries
Damien Monti, Erlendur Jonsson, Andrea Boschin, M Rosa Palacín, Alexandre Ponrouch, Patrik Johansson
Nov 05, 2020
The currently emerging sodium-ion battery technology is in need of an optimized standard organic solvent electrolyte based on solid and directly comparable data. With this aim we have made a systematic study of "simple"...
Primary post-transplant lymphoproliferative disorder of the central nervous system
Mary M Taj, Britta Maecker-Kolhoff, Rebecca Ling, Simon Bomken, Birgit Burkhardt, Alan KS Chiang, Monika Csoka, Anna Füreder, Stéphanie Haouy, Jelena Lazic, Natalia Miakova, Veronique Minard-Colin, Suzanne D Turner, Anne Uyttebroeck, Andishe Attarbaschi, the international Berlin-Frankfurt-Münster (i-BFM) Study Group European Intergroup for Childhood Non-Hodgkin’s Lymphoma (EICNHL)
Feb 17, 2021
Primary central nervous system (CNS) post-transplant lymphoproliferative disorder (PTLD) in childhood is rare. Twenty-five patients were retrieved from nine European Intergroup for Childhood Non-Hodgkin's Lymphoma and/or...
Central Nervous System outcome post-transplant lymphoproliferative disorder transplant Treatment Adolescent Adult Allografts Brain Neoplasms Child Child Preschool Disease-Free Survival Female Hematopoietic Stem Cell Transplantation Humans Infant Injections Spinal Lymphoproliferative Disorders Male Organ Transplantation Rituximab Survival Rate
European consensus statement on diagnosis and treatment of adult ADHD
Sandra JJ Kooij, Susanne Bejerot, Andrew Blackwell, Herve Caci, Miquel Casas-Brugué, Pieter J Carpentier, Dan Edvinsson, John Fayyad, Karin Foeken, Michael Fitzgerald, Veronique Gaillac, Ylva Ginsberg, Chantal Henry, Johanna Krause, Michael B Lensing, Iris Manor, Helmut Niederhofer, Carlos Nunes-Filipe, Martin D Ohlmeier, Pierre Oswald, Stefano Pallanti, Artemios Pehlivanidis, Josep A Ramos-Quiroga, Maria Rastam, Doris Ryffel-Rawak, Steven Stes, Philip Asherson
Aug 20, 2020
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that persists into adulthood in the majority of cases. The evidence on persistence poses several...
Controlling Al–M Interactions in Group 1 Metal Aluminyls (M = Li, Na, and K). Facile Conversion of Dimers to Monomeric and Separated Ion Pairs
The aluminyl compounds [M{Al(NONDipp)}]2 (NONDipp = [O(SiMe2NDipp)2]2–, Dipp = 2,6-iPr2C6H3), which exist as contacted dimeric pairs in both the solution and solid states, have been converted to monomeric ion pairs and separated...
Controlling Al–M Interactions in Group 1 Metal Aluminyls (M = Li, Na, and K). Facile Conversion of Dimers to Monomeric and Separated Ion Pairs
The aluminyl compounds [M{Al(NONDipp)}]2 (NONDipp = [O(SiMe2NDipp)2]2–, Dipp = 2,6-iPr2C6H3), which exist as contacted dimeric pairs in both the solution and solid states, have been converted to monomeric ion pairs and separated...
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
Surveillance recommendations for DICER1 pathogenic variant carriers
Jette J Bakhuizen, Helen Hanson, Karin van der Tuin, Fiona Lalloo, Marc Tischkowitz, Karin Wadt, Marjolijn CJ Jongmans, SIOPE Host Genome Working Group, CanGene-CanVar Clinical Guideline Working Group, Expert Network Members
Oct 01, 2021
DICER1 syndrome is a rare genetic disorder that predisposes to a wide spectrum of tumors. Developing surveillance protocols for this syndrome is challenging because uncertainty exists about the clinical efficacy of surveillance...
Mycophenolate mofetil vs azathioprine for remission maintenance in antineutrophil cytoplasmic antibody-associated vasculitis
Thomas F Hiemstra, Michael Walsh, Alfred Mahr, Caroline O Savage, Kirsten de Groot, Lorraine Harper, Thomas Hauser, Irmgard Neumann, Vladimir Tesar, Karl-Martin Wissing, Christian Pagnoux, Wilhelm Schmitt, David RW Jayne, European Vasculitis Study Group (EUVAS)
Aug 05, 2019
CONTEXT: Current remission maintenance therapies for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are limited by partial efficacy and toxicity. OBJECTIVE: To compare the effects of mycophenolate mofetil...
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
New European tricksters
In the context of contemporary European labour migration, where the most publicised pattern of labour migration sees Eastern European migrants move West, the dominant scholarly interpretation of Polish jokes is not applicable...
Gravettian cranial morphology and human group affinities during the European Upper Palaeolithic.
Aurélien Mounier, Yann Heuzé, Mathilde Samsel, Sergey Vasilyev, Laurent Klaric, Sébastien Villotte
Dec 22, 2020
Archaeologically defined Upper Palaeolithic (UP, 45,000-10,000 years ago) "cultures" are often used as proxies to designate fossil populations. While recent genomic studies have partly clarified the complex relationship between...
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Lourdes Ortiz-Fernández, Francisco David Carmona, Raquel López-Mejías, Maria Francisca González-Escribano, Paul A Lyons, Ann W Morgan, Amr H Sawalha, Peter A Merkel, Kenneth GC Smith, Miguel A González-Gay, Javier Martín, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group Spanish GCA Study Group
Apr 18, 2018
OBJETIVE: Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we...
Autoantibodies outcomes research systemic sclerosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Case-Control Studies Epigenesis Genetic Female Genetic Loci Genetic Predisposition to Disease Giant Cell Arteritis HLA-DQ Antigens HLA-DQ beta-Chains Humans Jumonji Domain-Containing Histone Demethylases Linkage Disequilibrium Male Phenotype Polymorphism Single Nucleotide Protein Array Analysis Systemic Vasculitis Takayasu arteritis
New European tricksters
In the context of contemporary European labour migration, where the most publicised pattern of labour migration sees Eastern European migrants move West, the dominant scholarly interpretation of Polish jokes is not applicable...
EU-AIMS Longitudinal European Autism Project (LEAP)
Johan Isaksson, Kristiina Tammimies, Janina Neufeld, Élodie Cauvet, Karl Lundin, Jan K Buitelaar, Eva Loth, Declan GM Murphy, Will Spooren, Sven Bölte, EU-AIMS LEAP group
May 09, 2019
EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) has...
European temporal trends in the use of lymph node dissection in patients with renal cancer
U Capitanio, GD Stewart, A Larcher, I Ouzaid, B Akdogan, M Roscigno, M Marszalek, P Dell'Oglio, M Salagierski, A Volpe, MC Mir, M Kriegmair, C Terrone, SD Brookman-May, F Montorsi, T Klatte, Kidney Cancer Working Group of the Young Academic Urologists (YAU) Working Party of the European Association of Urology (EAU)
Oct 04, 2017
BACKGROUND: The role of lymph node dissection (LND) in renal cell carcinoma (RCC) is still under debate. We aimed to assess the utilization rates of LND over time in Europe. METHODS: A multi-institutional database of 13,581 RCC...
Physical Activity in the Prevention of Childhood Obesity
Justyna Wyszyńska, Susanne Ring-Dimitriou, David Thivel, Daniel Weghuber, Adamos Hadjipanayis, Zachi Grossman, Robert Ross-Russell, Katarzyna Dereń, Artur Mazur
Nov 19, 2020
Obesity affects an increasing number of children and adolescents. Physical activity (PA) is a significant factor in the prevention of excessive body mass in the pediatric population. A significant percentage of pediatric...
Social brain activation during mentalizing in a large autism cohort
Carolin Moessnang, Sarah Baumeister, Julian Tillmann, David Goyard, Tony Charman, Sara Ambrosino, Simon Baron-Cohen, Christian Beckmann, Sven Bölte, Carsten Bours, Daisy Crawley, Flavio Dell'Acqua, Sarah Durston, Christine Ecker, Vincent Frouin, Hannah Hayward, Rosemary Holt, Mark Johnson, Emily Jones, Meng-Chuan Lai, Michael V Lombardo, Luke Mason, Marianne Oldenhinkel, Antonio Persico, Antonia San José Cáceres, Will Spooren, Eva Loth, Declan GM Murphy, Jan K Buitelaar, Tobias Banaschewski, Daniel Brandeis, Heike Tost, Andreas Meyer-Lindenberg, EU-AIMS LEAP group
Mar 09, 2020
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition with key deficits in social functioning. It is widely assumed that the biological underpinnings of social impairment are neurofunctional alterations in...
A EUROPEAN EDUCATION
Patricia Walsh
Dec 14, 2019
During the early twentieth century, a myriad of progressive movements would form in the United States to better the social status of women. These movements had rich roots in their European counterparts and often fed off the...
Published by: Department of History, University of Karachi
Towards prediction of ordered phases in rechargeable battery chemistry via group–subgroup transformation
Yunbing Ran, Zheyi Zou, Bo Liu, Da Wang, Bowei Pu, Penghui Mi, Wei Shi, Yajie Li, Bing He, Ziheng Lu, Xia Lu, Baihai Li, Siqi Shi
Jan 28, 2022
Abstract: The electrochemical thermodynamic and kinetic characteristics of rechargeable batteries are critically influenced by the ordering of mobile ions in electrodes or solid electrolytes. However, because of the experimental...
Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis
Alessandra Bettiol, Maria Letizia Urban, Lorenzo Dagna, Vincent Cottin, Franco Franceschini, Stefano Del Giacco, Franco Schiavon, Thomas Neumann, Giuseppe Lopalco, Pavel Novikov, Chiara Baldini, Carlo Lombardi, Alvise Berti, Federico Alberici, Marco Folci, Simone Negrini, Renato Alberto Sinico, Luca Quartuccio, Claudio Lunardi, Paola Parronchi, Frank Moosig, Georgina Espígol-Frigolé, Jan Schroeder, Anna Luise Kernder, Sara Monti, Ettore Silvagni, Claudia Crimi, Francesco Cinetto, Paolo Fraticelli, Dario Roccatello, Angelo Vacca, Aladdin J Mohammad, Bernhard Hellmich, Maxime Samson, Elena Bargagli, Jan Willem Cohen Tervaert, Camillo Ribi, Davide Fiori, Federica Bello, Filippo Fagni, Luca Moroni, Giuseppe Alvise Ramirez, Mouhamad Nasser, Chiara Marvisi, Paola Toniati, Davide Firinu, Roberto Padoan, Allyson Egan, Benjamin Seeliger, Florenzo Iannone, Carlo Salvarani, David Jayne, Domenico Prisco, Augusto Vaglio, Giacomo Emmi, European EGPA Study Group
Jan 07, 2022
OBJECTIVE: Mepolizumab proved to be an efficacious treatment for eosinophilic granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the randomized, controlled MIRRA trial. In a few recently reported...
Gray matter covariations and core symptoms of autism
Ting Mei, Alberto Llera, Dorothea L Floris, Natalie J Forde, Julian Tillmann, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Rosemary J Holt, Simon Baron-Cohen, Annika Rausch, Eva Loth, Flavio Dell'Acqua, Tony Charman, Declan GM Murphy, Christine Ecker, Christian F Beckmann, Jan K Buitelaar, EU-AIMS LEAP group
Dec 07, 2020
BACKGROUND: Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influence of...
The transferability of lipid loci across African, Asian and European cohorts.
Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley, Anatoli Kamali, Gershim Asiki, Iona Y Millwood, Michael Holmes, Huaidong Du, Yu Guo, Meena Kumari, George Dedoussis, Liming Li, Zhengming Chen, Manjinder S Sandhu, Eleftheria Zeggini, Understanding Society Scientific Group
Oct 29, 2019
Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populations. Genetic correlations...
2021 roadmap for sodium-ion batteries
Nuria Tapia-Ruiz, A Robert Armstrong, Hande Alptekin, Marco A Amores, Heather Au, Jerry Barker, Rebecca Boston, William R Brant, Jake M Brittain, Yue Chen, Manish Chhowalla, Yong-Seok Choi, Sara I R Costa, Maria Crespo Ribadeneyra, Serena A Cussen, Edmund J Cussen, William I F David, Aamod V Desai, Stewart A M Dickson, Emmanuel I Eweka, Juan D Forero-Saboya, Clare P Grey, John M Griffin, Peter Gross, Xiao Hua, John T S Irvine, Patrik Johansson, Martin O Jones, Martin Karlsmo, Emma Kendrick, Eunjeong Kim, Oleg V Kolosov, Zhuangnan Li, Stijn F L Mertens, Ronnie Mogensen, Laure Monconduit, Russell E Morris, Andrew J Naylor, Shahin Nikman, Christopher A O’Keefe, Darren M C Ould, R G Palgrave, Philippe Poizot, Alexandre Ponrouch, Stéven Renault, Emily M Reynolds, Ashish Rudola, Ruth Sayers, David O Scanlon, S Sen, Valerie R Seymour, Begoña Silván, Moulay Tahar Sougrati, Lorenzo Stievano, Grant S Stone, Chris I Thomas, Maria-Magdalena Titirici, Jincheng Tong, Thomas J Wood, Dominic S Wright, Reza Younesi
Jul 28, 2021
Abstract: Increasing concerns regarding the sustainability of lithium sources, due to their limited availability and consequent expected price increase, have raised awareness of the importance of developing alternative...
2021 roadmap for sodium-ion batteries
Nuria Tapia-Ruiz, A Robert Armstrong, Hande Alptekin, Marco A Amores, Heather Au, Jerry Barker, Rebecca Boston, William R Brant, Jake M Brittain, Yue Chen, Manish Chhowalla, Yong-Seok Choi, Sara I R Costa, Maria Crespo Ribadeneyra, Serena A Cussen, Edmund J Cussen, William I F David, Aamod V Desai, Stewart A M Dickson, Emmanuel I Eweka, Juan D Forero-Saboya, Clare P Grey, John M Griffin, Peter Gross, Xiao Hua, John T S Irvine, Patrik Johansson, Martin O Jones, Martin Karlsmo, Emma Kendrick, Eunjeong Kim, Oleg V Kolosov, Zhuangnan Li, Stijn F L Mertens, Ronnie Mogensen, Laure Monconduit, Russell E Morris, Andrew J Naylor, Shahin Nikman, Christopher A O’Keefe, Darren M C Ould, R G Palgrave, Philippe Poizot, Alexandre Ponrouch, Stéven Renault, Emily M Reynolds, Ashish Rudola, Ruth Sayers, David O Scanlon, S Sen, Valerie R Seymour, Begoña Silván, Moulay Tahar Sougrati, Lorenzo Stievano, Grant S Stone, Chris I Thomas, Maria-Magdalena Titirici, Jincheng Tong, Thomas J Wood, Dominic S Wright, Reza Younesi
Jul 28, 2021
Abstract: Increasing concerns regarding the sustainability of lithium sources, due to their limited availability and consequent expected price increase, have raised awareness of the importance of developing alternative...
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