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Use of multidimensional item response theory methods for dementia prevalence prediction
GBD 2019 Dementia Collaborators
Oct 11, 2021
BACKGROUND: Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic evaluations of dementia prevalence are prohibitively resource-intensive in many settings. However...
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016
GBD 2016 Dementia Collaborators
Feb 08, 2019
BACKGROUND: The number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world. A successful response to these challenges requires an accurate...
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017
GBD 2017 Risk Factor Collaborators
Sep 18, 2019
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising...
Adolescent Adult Age Distribution Aged Aged 80 and over Child Child Preschool Disabled Persons Environmental Exposure Female Global Burden of Disease Global Health Health Risk Behaviors Humans Infant Infant Newborn Life Expectancy Male Metabolic Diseases Middle Aged Occupational Diseases occupational exposure Quality-Adjusted Life Years Risk Assessment Sex Distribution Socioeconomic Factors Young Adult
Global, regional, and national burden of neurological disorders, 1990-2016
GBD 2016 Neurology Collaborators
Sep 18, 2019
BACKGROUND: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to...
Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017
GBD 2017 Causes of Death Collaborators
Feb 01, 2019
BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated...
Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories
GBD 2017 SDG Collaborators
Sep 18, 2019
BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on...
Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015
GBD 2015 Healthcare Access and Quality Collaborators. Electronic address: cjlm@uw.edu, GBD 2015 Healthcare Access and Quality Collaborators
Dec 12, 2017
BACKGROUND: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality)....
Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015
GBD 2015 Child Mortality Collaborators
Nov 30, 2017
BACKGROUND: Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 2015. At the country level...
Measuring the health-related Sustainable Development Goals in 188 countries
GBD 2015 SDG Collaborators
Nov 21, 2017
BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33...
Health trends, inequalities and opportunities in South Africa's provinces, 1990-2019
Tom Achoki, Benn Sartorius, David Watkins, Scott D Glenn, Andre Pascal Kengne, Tolu Oni, Charles Shey Wiysonge, Alexandra Walker, Olatunji O Adetokunboh, Tesleem Kayode Babalola, Obasanjo Afolabi Bolarinwa, Mareli M Claassens, Richard G Cowden, Candy T Day, Oluchi Ezekannagha, Themba G Ginindza, Chidozie CD Iwu, Chinwe Juliana Iwu, Innocent Karangwa, Patrick Dmc Katoto, Nuworza Kugbey, Desmond Kuupiel, Phetole Walter Mahasha, Tivani Phosa Mashamba-Thompson, George A Mensah, Duduzile Edith Ndwandwe, Chukwudi A Nnaji, Mpiko Ntsekhe, Thomas Elliot Nyirenda, Julius Nyerere Odhiambo, Kwaku Oppong Asante, Charles DH Parry, Julian David Pillay, Aletta Elisabeth Schutte, Soraya Seedat, Karen Sliwa, Dan J Stein, Frank C Tanser, Ushotanefe Useh, Heather J Zar, Liesl J Zühlke, Bongani M Mayosi, Simon I Hay, Christopher JL Murray, Mohsen Naghavi
Mar 02, 2022
BACKGROUND: Over the last 30 years, South Africa has experienced four 'colliding epidemics' of HIV and tuberculosis, chronic illness and mental health, injury and violence, and maternal, neonatal, and child mortality, which have...
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from...
Health trends, inequalities and opportunities in South Africa's provinces, 1990-2019
Tom Achoki, Benn Sartorius, David Watkins, Scott D Glenn, Andre Pascal Kengne, Tolu Oni, Charles Shey Wiysonge, Alexandra Walker, Olatunji O Adetokunboh, Tesleem Kayode Babalola, Obasanjo Afolabi Bolarinwa, Mareli M Claassens, Richard G Cowden, Candy T Day, Oluchi Ezekannagha, Themba G Ginindza, Chidozie CD Iwu, Chinwe Juliana Iwu, Innocent Karangwa, Patrick Dmc Katoto, Nuworza Kugbey, Desmond Kuupiel, Phetole Walter Mahasha, Tivani Phosa Mashamba-Thompson, George A Mensah, Duduzile Edith Ndwandwe, Chukwudi A Nnaji, Mpiko Ntsekhe, Thomas Elliot Nyirenda, Julius Nyerere Odhiambo, Kwaku Oppong Asante, Charles DH Parry, Julian David Pillay, Aletta Elisabeth Schutte, Soraya Seedat, Karen Sliwa, Dan J Stein, Frank C Tanser, Ushotanefe Useh, Heather J Zar, Liesl J Zühlke, Bongani M Mayosi, Simon I Hay, Christopher JL Murray, Mohsen Naghavi
Jan 28, 2022
BACKGROUND: Over the last 30 years, South Africa has experienced four 'colliding epidemics' of HIV and tuberculosis, chronic illness and mental health, injury and violence, and maternal, neonatal, and child mortality, which have...
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015
GBD 2015 Mortality and Causes of Death Collaborators
Nov 21, 2017
BACKGROUND: Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a...
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016
GBD 2016 Mortality Collaborators
Oct 03, 2018
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause...
Adolescent Adult Age Distribution Aged Aged 80 and over Birth Rate Cause of Death Child Child Preschool Educational Status Female Global Burden of Disease Global Health HIV Infections Humans Infant Infant Newborn Life Expectancy Male Middle Aged Socioeconomic Factors Stillbirth Survival Rate Young Adult
Population and fertility by age and sex for 195 countries and territories, 1950-2017
GBD 2017 Population and Fertility Collaborators
Sep 18, 2019
BACKGROUND: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of...
Dementia
Summary: The Lancet Commission on Dementia Prevention, Intervention, and Care has evaluated current evidence on dementia management, including the measures that can be taken to reduce an individual’s risk of dementia. However...
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and...
Adolescent Adult Age Distribution Aged Aged 80 and over Child Child Preschool Disabled Persons Female Global Burden of Disease Global Health Humans Incidence Infant Infant Newborn Life Expectancy Male Middle Aged Morbidity prevalence Sex Distribution Socioeconomic Factors Wounds and Injuries Young Adult
The global burden of typhoid and paratyphoid fevers
GBD 2017 Typhoid and Paratyphoid Collaborators
Apr 18, 2019
BACKGROUND: Efforts to quantify the global burden of enteric fever are valuable for understanding the health lost and the large-scale spatial distribution of the disease. We present the estimates of typhoid and paratyphoid fever...
Adolescent Adult Aged Aged 80 and over Cause of Death Child Child Preschool Disabled Persons Female Global Burden of Disease Humans Incidence Infant Life Expectancy Male Mass Vaccination Middle Aged Paratyphoid Fever Quality-Adjusted Life Years Risk Factors Salmonella enterica Sanitation Typhoid Fever Typhoid-Paratyphoid Vaccines Young Adult
Global, regional, and national levels of maternal mortality, 1990-2015
GBD 2015 Maternal Mortality Collaborators
Nov 30, 2017
BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success...
Dementia-friendly communities
Elspeth Mathie, Arthur Antony, Anne Killett, Nicole Darlington, Stefanie Buckner, Louise Lafortune, Andrea Mayrhofer, Angela Dickinson, Michael Woodward, Claire Goodman
May 16, 2022
BACKGROUND: Dementia Friendly Communities (DFCs) offer an approach to community engagement to improve the lives of people living with dementia and their family supporters. The involvement of those living with dementia is key to...
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017
GBD 2017 DALYs and HALE Collaborators
Feb 08, 2019
BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and...
Association between midlife dementia risk factors and longitudinal brain atrophy
John T O'Brien, Michael J Firbank, Karen Ritchie, Katie Wells, Guy B Williams, Craig W Ritchie, Li Su
Dec 11, 2019
Background: Increased rates of brain atrophy on serial MRI are frequently used as a surrogate marker of disease progression in Alzheimer’s disease and other dementias. However, the extent to which they are associated with future...
ICC-dementia (International Centenarian Consortium - dementia)
Henry Brodaty, Claudia Woolf, Stacy Andersen, Nir Barzilai, Carol Brayne, Karen Siu-Lan Cheung, Maria M Corrada, John D Crawford, Catriona Daly, Yasuyuki Gondo, Bo Hagberg, Nobuyoshi Hirose, Henne Holstege, Claudia Kawas, Jeffrey Kaye, Nicole A Kochan, Bobo Hi-Po Lau, Ugo Lucca, Gabriella Marcon, Peter Martin, Leonard W Poon, Robyn Richmond, Jean-Marie Robine, Ingmar Skoog, Melissa J Slavin, Jan Szewieczek, Mauro Tettamanti, José Viña, Thomas Perls, Perminder S Sachdev
Sep 29, 2016
BACKGROUND: Considerable variability exists in international prevalence and incidence estimates of dementia. The accuracy of estimates of dementia in the oldest-old and the controversial question of whether dementia incidence...
Trauma and depressive symptomatology in middle-aged persons at high risk of dementia
Karen Ritchie, Isabelle Carrière, Sarah Gregory, Tam Watermeyer, Samuel Danso, Li Su, Craig W Ritchie, John T O'Brien
Sep 28, 2020
OBJECTIVE: Depression and trauma are associated with changes in brain regions implicated in Alzheimer's disease. The present study examined associations between childhood trauma, depression, adult cognitive functioning and risk...
Trauma and depressive symptomatology in middle-aged persons at high risk of dementia
Karen Ritchie, Isabelle Carrière, Sarah Gregory, Tam Watermeyer, Samuel Danso, Li Su, Craig W Ritchie, John T O'Brien
Oct 23, 2020
Objective: Depression and trauma are associated with changes in brain regions implicated in Alzheimer’s disease. The present study examined associations between childhood trauma, depression, adult cognitive functioning and risk...
Published by: BMJ Publishing Group
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