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Recommendation-Based Meta-Search Engine for Suggesting Relevant Documents Links
The information available online is mostly present in an unstructured form and search engines are indispensable tools especially in higher education organizations for obtaining information from the Internet. Various search...
Published by: IGI Global Scientific Publishing
Harris Hawks Jaya Algorithm-Based Routing Protocol in Delay Tolerant Network
This paper introduces a trust-based multipath routing protocol for exploiting different paths between source as well as destination to mitigate energy constraints. The key idea is to determine optimal path from the entire paths...
Published by: IGI Global Scientific Publishing
Optimization of DH Parameters of 6R Robotic Manipulator Using JAYA Approach
Manipulation of robots is carried out by the operators through a sequence of commands. However, the accuracy of the manipulation is still hindered due to parameter uncertainty. This results in less accurate robotic operations...
Published by: IGI Global Scientific Publishing
Effect Of Service Quality And Company Image On Customer Loyalty
This study is entitled The Effect of Service Quality and Company Image on Customer Loyalty at PT. BPR Sari Jaya Sedana in Klungkung. The formulation of the problem is: How is the influence of service quality and company image on...
Published by: Indonesia Strategic Sustainability
B-cell depletion in SLE
B cells are believed to be central to the disease process in systemic lupus erythematosus (SLE), making them a target for new therapeutic intervention. In recent years there have been many publications regarding the experience...
A complete description of thermodynamic stabilities of molecular crystals.
Predictions of relative stabilities of (competing) molecular crystals are of great technological relevance, most notably for the pharmaceutical industry. However, they present a long-standing challenge for modeling, as often...
MPPT Control of Photovoltaic Systems Using Statechart With Abstraction and Its Comparison With Fuzzy Logic
Maximum power point tracking(MPPT) control is an indispensable aspect of photovoltaic(PV) systems. Many MPPT techniques including a few based on soft-computing have been employed earlier. The soft-computing techniques include...
Published by: IGI Global Scientific Publishing
A genome–wide screen to identify genes controlling the rate of entry into mitosis in fission yeast
Naomi Moris, Jaya Shrivastava, Linda Jeffery, Juan-Juan Li, Jacqueline Hayles, Paul Nurse
Feb 11, 2019
We have carried out a haploinsufficiency (HI) screen in fission yeast using heterozygous deletion diploid mutants of a genome-wide set of cell cycle genes to identify genes encoding products whose level determines the rate of...
Biofunctionalised bacterial cellulose scaffold supports the patterning and expansion of human embryonic stem cell-derived dopaminergic progenitor cells.
Miranda Robbins, Venkat Pisupati, Roberta Azzarelli, Samer I Nehme, Roger Barker, Ljiljana Fruk, Gabriele S Kaminski Schierle
Nov 22, 2021
Maternal immunisation against Group B Streptococcus
Simon R Procter, Bronner P Gonçalves, Proma Paul, Jaya Chandna, Farah Seedat, Artemis Koukounari, Raymond Hutubessy, Caroline Trotter, Joy E Lawn, Mark Jit
Mar 14, 2023
Lifetime risk of diabetes in metropolitan cities in India.
Shammi Luhar, Dimple Kondal, Rebecca Jones, Ranjit M Anjana, Shivani A Patel, Sanjay Kinra, Lynda Clarke, Mohammed K Ali, Dorairaj Prabhakaran, M Masood Kadir, Nikhil Tandon, Viswanathan Mohan, KM Venkat Narayan
Feb 05, 2021
AIMS/HYPOTHESIS: We aimed to estimate the lifetime risk of diabetes and diabetes-free life expectancy in metropolitan cities in India among the population aged 20 years or more, and their variation by sex, age and BMI. METHODS...
Body Mass Index Diabetes Diabetes-free life expectancy india lifetime risk Metropolitan cities urban Adult Age Distribution Diabetes mellitus Disease-Free Survival Female Humans Incidence india Life Expectancy Male Markov Chains Middle Aged Models Theoretical obesity prevalence Risk Assessment Risk Factors Sex Distribution Time Factors Urban Health Young Adult
Application of Metaheuristic Approaches for the Variable Selection Problem
Variable selection is an old topic from regression models. Besides many conventional approaches, some metaheuristic approaches from the realm of optimization such as GA (Genetic Algorithm) or simulated annealing have been...
Published by: IGI Global Scientific Publishing
A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization.
Anand D Jeyasekharan, Yang Liu, Hiroyoshi Hattori, Venkat Pisupati, Asta Bjork Jonsdottir, Eeson Rajendra, MiYoung Lee, Elayanambi Sundaramoorthy, Simon Schlachter, Clemens F Kaminski, Yaara Ofir-Rosenfeld, Ko Sato, Jane Savill, Nabieh Ayoub, Ashok R Venkitaraman
Feb 13, 2020
Germline missense mutations affecting a single BRCA2 allele predispose humans to cancer. Here we identify a protein-targeting mechanism that is disrupted by the cancer-associated mutation, BRCA2(D2723H), and that controls the...
Maternal immunisation against Group B Streptococcus
Simon R Procter, Bronner P Gonçalves, Proma Paul, Jaya Chandna, Farah Seedat, Artemis Koukounari, Raymond Hutubessy, Caroline Trotter, Joy E Lawn, Mark Jit
Apr 14, 2023
Background
Group B Streptococcus (GBS) can cause invasive disease (iGBS) in young infants, typically presenting as sepsis or meningitis, and is also associated with stillbirth and preterm birth. GBS vaccines are under...
Humans Streptococcus Agalactiae Streptococcal Infections premature birth vaccines Immunization Vaccination Bayes Theorem Pregnancy Quality of life Infant Infant Newborn Cost-Benefit Analysis Female Stillbirth
Published by: PLoS Medicine
Biofunctionalised bacterial cellulose scaffold supports the patterning and expansion of human embryonic stem cell-derived dopaminergic progenitor cells.
Miranda Robbins, Venkat Pisupati, Roberta Azzarelli, Samer I Nehme, Roger A Barker, Ljiljana Fruk, Gabriele S Kaminski Schierle
Jan 07, 2022
BACKGROUND: Stem cell-based therapies for neurodegenerative diseases like Parkinson's disease are a promising approach in regenerative medicine and are now moving towards early stage clinical trials. However, a number of...
Impact of dengue fever on liver function tests and to relate liver function tests with severity of disease
B. Manohar, N. Madhavi Latha, T. Jaya Chandra Naidu, K. Madhavi, B. Sasi Kumar, Shankar Reddy Dudala, C. Naveen Kumar
Jul 01, 2015
Introduction: Dengue fever is an ancient disease. The earliest record found today is in a Chinese encyclopedia of disease symptoms and remedies, first published during Chin dynasty (265 to 420 AD). Severe Dengue was first...
Published by: IJHS Medical Association
Impact of dengue fever on liver function tests and to relate liver function tests with severity of disease
B. Manohar, N. Madhavi Latha, T. Jaya Chandra Naidu, K. Madhavi, B. Sasi Kumar, Shankar Reddy Dudala, C. Naveen Kumar
Jul 01, 2015
Introduction: Dengue fever is an ancient disease. The earliest record found today is in a Chinese encyclopedia of disease symptoms and remedies, first published during Chin dynasty (265 to 420 AD). Severe Dengue was first...
Published by: IJHS Medical Association
Impulsivity in abstinent alcohol and polydrug dependence
Eleanor M Taylor, Anna Murphy, Venkat Boyapati, Karen D Ersche, Remy Flechais, Shankar Kuchibatla, John McGonigle, Anotonio Metastasio, Liam Nestor, Csaba Orban, Fillippo Passetti, Louise Paterson, Dana Smith, John Suckling, Roger Tait, Anne R Lingford-Hughes, Trevor W Robbins, David J Nutt, JF William Deakin, Rebecca Elliott, ICCAM Platform
Mar 10, 2016
Pregnancy Vitamin D Supplementation and Childhood Bone Mass at Age 4 Years
Elizabeth M Curtis, Rebecca J Moon, Stefania D'Angelo, Sarah R Crozier, Nicholas J Bishop, Jaya Sujatha Gopal-Kothandapani, Stephen H Kennedy, Aris T Papageorghiou, Robert Fraser, Saurabh V Gandhi, Inez Schoenmakers, Ann Prentice, Hazel M Inskip, Keith M Godfrey, M Kassim Javaid, Richard Eastell, Cyrus Cooper, Nicholas C Harvey, MAVIDOS Trial Group
Aug 21, 2022
In the Maternal Vitamin D Osteoporosis Study (MAVIDOS) randomized trial, vitamin D supplementation in pregnancy did not lead to greater neonatal bone mass across the trial as a whole, but, in a prespecified secondary analysis by...
Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage.
Jeremy P Koelmel, Wan Y Tan, Yang Li, John A Bowden, Atiye Ahmadireskety, Andrew C Patt, David J Orlicky, Ewy Mathé, Nicholas M Kroeger, David C Thompson, Jason A Cochran, Jaya Prakash Golla, Aikaterini Kandyliari, Ying Chen, Georgia Charkoftaki, Joy D Guingab-Cagmat, Hiroshi Tsugawa, Anmol Arora, Kirill Veselkov, Shunji Kato, Yurika Otoki, Kiyotaka Nakagawa, Richard A Yost, Timothy J Garrett, Vasilis Vasiliou
Nov 23, 2021
Alcoholic fatty liver disease (AFLD) is characterized by lipid accumulation and inflammation and can progress to cirrhosis and cancer in the liver. AFLD diagnosis currently relies on histological analysis of liver biopsies....
Pregnancy Vitamin D Supplementation and Childhood Bone Mass at Age 4 Years
Elizabeth M Curtis, Rebecca J Moon, Stefania D'Angelo, Sarah R Crozier, Nicholas J Bishop, Jaya Sujatha Gopal-Kothandapani, Stephen H Kennedy, Aris T Papageorghiou, Robert Fraser, Saurabh V Gandhi, Inez Schoenmakers, Ann Prentice, Hazel M Inskip, Keith M Godfrey, M Kassim Javaid, Richard Eastell, Cyrus Cooper, Nicholas C Harvey, MAVIDOS Trial Group
Jun 11, 2022
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Simon Eschweiler, Ciro Ramírez-Suástegui, Yingcong Li, Emma King, Lindsey Chudley, Jaya Thomas, Oliver Wood, Adrian von Witzleben, Danielle Jeffrey, Katy McCann, Hayley Simon, Monalisa Mondal, Alice Wang, Martina Dicker, Elena Lopez-Guadamillas, Ting-Fang Chou, Nicola A Dobbs, Louisa Essame, Gary Acton, Fiona Kelly, Gavin Halbert, Joseph J Sacco, Andrew Graeme Schache, Richard Shaw, James Anthony McCaul, Claire Paterson, Joseph H Davies, Peter A Brennan, Rabindra P Singh, Paul M Loadman, William Wilson, Allan Hackshaw, Gregory Seumois, Klaus Okkenhaug, Gareth J Thomas, Terry M Jones, Ferhat Ay, Greg Friberg, Mitchell Kronenberg, Bart Vanhaesebroeck, Pandurangan Vijayanand, Christian H Ottensmeier
May 25, 2022
Phosphoinositide 3-kinase δ (PI3Kδ) has a key role in lymphocytes, and inhibitors that target this PI3K have been approved for treatment of B cell malignancies1-3. Although studies in mouse models of solid tumours have...
Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
Katherine M Wilson, Eszter Katona, Idoia Glaria, Mireia Carcolé, Imogen J Swift, Aitana Sogorb-Esteve, Carolin Heller, Arabella Bouzigues, Amanda J Heslegrave, Ashvini Keshavan, Kathryn Knowles, Saurabh Patil, Susovan Mohapatra, Yuanjing Liu, Jaya Goyal, Raquel Sanchez-Valle, Robert Jr Laforce, Matthis Synofzik, James B Rowe, Elizabeth Finger, Rik Vandenberghe, Christopher R Butler, Alexander Gerhard, John C van Swieten, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Alexandre de Mendonça, Mario Masellis, M Carmela Tartaglia, Markus Otto, Caroline Graff, Simon Ducharme, Jonathan M Schott, Andrea Malaspina, Henrik Zetterberg, Ramakrishna Boyanapalli, Jonathan D Rohrer, Adrian M Isaacs, Genetic FTD Initiative (GENFI)
Apr 07, 2022
Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
Kathy Y. Liu, Rogier A. Kievit, Kamen A. Tsvetanov, Matthew J. Betts, Emrah Düzel, James B. Rowe, Robert Howard, Dorothea Hämmerer, Lorraine K. Tyler, Carol Brayne, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Richard N. Henson, Fiona E. Matthews, William D. Marslen-Wilson, Meredith A. Shafto, Karen Campbell, Teresa Cheung, Simon Davis, Linda Geerligs, Rogier Kievit, Anna McCarrey, Abdur Mustafa, Darren Price, David Samu, Jason R. Taylor, Matthias Treder, Janna van Belle, Nitin Williams, Lauren Bates, Tina Emery, Sharon Erzinçlioglu, Andrew Gadie, Sofia Gerbase, Stanimira Georgieva, Claire Hanley, Beth Parkin, David Troy, Tibor Auer, Marta Correia, Lu Gao, Emma Green, Rafael Henriques, Jodie Allen, Gillian Amery, Liana Amunts, Anne Barcroft, Amanda Castle, Cheryl Dias, Jonathan Dowrick, Melissa Fair, Hayley Fisher, Anna Goulding, Adarsh Grewal, Geoff Hale, Andrew Hilton, Frances Johnson, Patricia Johnston, Thea Kavanagh-Williamson, Magdalena Kwasniewska, Alison McMinn, Kim Norman, Jessica Penrose, Fiona Roby, Diane Rowland, John Sargeant, Maggie Squire, Beth Stevens, Aldabra Stoddart, Cheryl Stone, Tracy Thompson, Ozlem Yazlik, Dan Barnes, Marie Dixon, Jaya Hillman, Joanne Mitchell, Laura Villis
Apr 06, 2021
Abstract: The locus coeruleus (LC), the origin of noradrenergic modulation of cognitive and behavioral function, may play an important role healthy ageing and in neurodegenerative conditions. We investigated the functional...
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