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Cracking the enigma of mitochondrial-DNA variants and cancer.
Wei Wei, Patrick F Chinnery
Feb 12, 2020
A recent study by Yuan et al., [Ref. 11] published in Nature Genetics, demonstrated multidimensional molecular alterations of mitochondrial DNA in human cancers and provide an on-line catalogue of mitochondrial genomes in many...
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Optimisation for interconnected energy hub system with combined ground source heat pump and borehole thermal storage
Da Huo, Wei Wei, Simon Le Blond
Dec 01, 2018
Ground source heat pumps (GSHP) give zero-carbon emission heating at a residential level. However, as the heat is discharged, the temperature of the ground drops, leading to a poorer efficiency. Borehole inter-seasonal thermal...
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Cell reprogramming shapes the mitochondrial DNA landscape
Abstract: Individual induced pluripotent stem cells (iPSCs) show considerable phenotypic heterogeneity, but the reasons for this are not fully understood. Comprehensively analysing the mitochondrial genome (mtDNA) in 146 iPSC...
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Cell reprogramming shapes the mitochondrial DNA landscape.
Individual induced pluripotent stem cells (iPSCs) show considerable phenotypic heterogeneity, but the reasons for this are not fully understood. Comprehensively analysing the mitochondrial genome (mtDNA) in 146 iPSC and...
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Water Resources Assessment and Management for Nuclear Power Plants in China
To deal with global warming and energy shortage, nuclear power plants are constructed or planning to be constructed in China presently. The operation of a nuclear power plant consumes a great amount of water and discharges a lot...
Biparental inheritance of mitochondrial DNA revisited.
Evidence for a biparental mode of mitochondrial DNA (mtDNA) inheritance has been sparse and remains controversial. Recent studies using a range of complementary techniques do not support paternal transmission of mtDNA, and...
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Optimisation for interconnected energy hub system with combined ground source heat pump and borehole thermal storage
Da Huo, Wei Wei, Simon Le Blond
Dec 01, 2018
Ground source heat pumps (GSHP) give zero-carbon emission heating at a residential level. However, as the heat is discharged, the temperature of the ground drops, leading to a poorer efficiency. Borehole inter-seasonal thermal...
Published by:
Cell reprogramming shapes the mitochondrial DNA landscape.
Individual induced pluripotent stem cells (iPSCs) show considerable phenotypic heterogeneity, but the reasons for this are not fully understood. Comprehensively analysing the mitochondrial genome (mtDNA) in 146 iPSC and...
Published by: Nature Communications
Water Resources Assessment and Management for Nuclear Power Plants in China
To deal with global warming and energy shortage, nuclear power plants are constructed or planning to be constructed in China presently. The operation of a nuclear power plant consumes a great amount of water and discharges a lot...
Background sequence characteristics influence the occurrence and severity of disease-causing mtDNA mutations.
Inherited mitochondrial DNA (mtDNA) mutations have emerged as a common cause of human disease, with mutations occurring multiple times in the world population. The clinical presentation of three pathogenic mtDNA mutations is...
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Research on the Compound Optimization Method of the Electrical and Thermal Properties of SiC/EP Composite Insulating Material.
In this paper, in order to improve the electrical and thermal properties of SiC/EP composites, the methods of compounding different crystalline SiC and micro-nano SiC particles are used to optimize them. Under different compound...
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Research on the Compound Optimization Method of the Electrical and Thermal Properties of SiC/EP Composite Insulating Material
In this paper, in order to improve the electrical and thermal properties of SiC/EP composites, the methods of compounding different crystalline SiC and micro-nano SiC particles are used to optimize them. Under different compound...
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Formulation of Locational Marginal Electricity-Carbon Price in Power Systems
Decarbonisation of power systems is essential for realising carbon neutrality, in which the economic cost caused by carbon is needed to be qualified. Based on the formulation of locational marginal price (LMP), this paper...
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Formulation of Locational Marginal Electricity-Carbon Price in Power Systems
Decarbonisation of power systems is essential for realising carbon neutrality, in which the economic cost caused by carbon is needed to be qualified. Based on the formulation of locational marginal price (LMP), this paper...
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Security Enhancement Through Compiler-Assisted Software Diversity With Deep Reinforcement Learning
Traditional software defenses take corresponding actions after the attacks are discovered. The defenders in this situation are comparatively passive because the attackers may try many different ways to find vulnerability and...
An atlas of mitochondrial DNA genotype-phenotype associations in the UK Biobank.
Mitochondrial DNA (mtDNA) variation in common diseases has been underexplored, partly due to a lack of genotype calling and quality-control procedures. Developing an at-scale workflow for mtDNA variant analyses, we show...
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