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Teaching and Learning for Global Citizenship in the EFL Classroom
This chapter reports on a case study that aimed to understand how global citizenship education (GCE) can be integrated in the English as a Foreign Language (EFL) curriculum. In order to do that, the authors analyze the practicum...
Sustainable Development Education Curriculum Development and Instructional Design Social Sciences and Humanities
Published by: IGI Global Scientific Publishing
Triggers of the Postural Display of Courtship in Drosophila persimilis Flies.
D. persimilis courtship shows some flexibility and courting males sometimes perform an elaborate postural display in addition to the standard courtship behaviours shared by most Drosophila species. This postural display includes...
Metaplastic Cdx2-depleted cells can be very disruptive neighbors.
In this issue of JEM, Balbinot et al. (https://doi.org/10.1084/jem.20170934) describe an original mechanism where Cdx2 inactivation regulates intestinal metaplastic to neoplastic transition in a paracrine fashion. Surprisingly...
A Framework for Public eServices Transparency
Rui Lourenço
Jan 01, 2023
Different aspects of government transparency have been analyzed by the research community, but no structured framework was found concerning public eServices transparency. This article considers transparency from a service users'...
Published by: IGI Global Scientific Publishing
Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing.
Ann-Sofie Thorsen, Doran Khamis, Richard Kemp, Mathilde Colombé, Filipe C Lourenço, Edward Morrissey, Douglas Winton
Oct 20, 2020
Somatic models of tissue pathology commonly use induction of gene-specific mutations in mice mediated by spatiotemporal regulation of Cre recombinase. Subsequent investigation of the onset and development of disease can be...
Cancer epithelial Intestine Lineage tracing Animals Antibodies Monoclonal Cell Lineage Colon Epithelial Cells Epithelium Escherichia coli Proteins Female Integrases Intestinal Mucosa Intestinal Neoplasms Intestine Small Intestines Male Mice Mice Inbred C57BL Mutation Neoplasms Probability Recombinases Stem Cells beta Catenin
‘We Are Not Racists, We Are Mexicans’
This article analyses the conflicting understandings surrounding the recognition of anti-black racism in Mexico, drawing from an analysis of the 2005 controversy around Memín Pinguín. We ask what is at stake when opposition...
Direitos Sociais na Constituição Uma Análise da Constitucionalização dos Direitos Sociais em Portugal, 1975-76
Embora todas as constituições incluam direitos, e muitas delas incluam direitos sociais, a verdade é que algumas são mais generosas do que outras a este respeito. Mas nenhuma se aproxima da Constituição da República Portuguesa...
Competing species leave many potential niches unfilled
A cornerstone of biology is that coexisting species evolve to occupy separate ecological niches. Classical theory predicts that interspecific competition should lead to all potential niches being occupied, yet observational data...
Competing species leave many potential niches unfilled
A cornerstone of biology is that coexisting species evolve to occupy separate ecological niches. Classical theory predicts that interspecific competition should lead to all potential niches being occupied, yet observational data...
A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype.
Ana Quelle-Regaldie, Mónica Folgueira, Julián Yáñez, Daniel Sobrido-Cameán, Anabel Alba-González, Antón Barreiro-Iglesias, María-Jesús Sobrido, Laura Sánchez
Aug 01, 2022
NOP56 belongs to a C/D box small nucleolar ribonucleoprotein complex that is in charge of cleavage and modification of precursor ribosomal RNAs and assembly of the 60S ribosomal subunit. An intronic expansion in NOP56 gene...
Decision-making in crisis resolution and home treatment teams
Chiara Lombardo, Mónica Santos, Tine Van Bortel, Robert Croos, Ella Arensman, Manaan Kar Ray
Feb 27, 2019
The aim of the study is to improve patient safety by identifying factors influencing gatekeeping decisions by crisis resolution and home treatment teams. A theoretical sampling method was used to recruit clinicians....
Autism screening and conditional cash transfers in Chile
Andres Roman-Urrestarazu, Carolina Yáñez, Claudia López-Garí, Constanza Elgueta, Carrie Allison, Carol Brayne, Mónica Troncoso, Simon Baron-Cohen
May 11, 2021
Diagnosis of Autism Spectrum Conditions (ASC) can be an extended procedure since ASC tend to both vary greatly across individual symptoms and diagnostic pathways with serious challenges to opportune access and diagnosis in low...
New law puts Bolivian biodiversity hotspot on road to deforestation.
Álvaro Fernández-Llamazares, Joose Helle, Johanna Eklund, Andrew Balmford, R Mónica Moraes, Victoria Reyes-García, Mar Cabeza
Jan 23, 2018
In August 2017, the Bolivian government passed a contentious law downgrading the legal protection of the Isiboro-Sécure National Park and Indigenous Territory (TIPNIS, for its Spanish acronym), the ancestral homeland of four...
Superoxide Dismutase-3 Downregulates Laminin α5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling.
Lorena Carmona-Rodríguez, Diego Martínez-Rey, Paula Martín-González, Mónica Franch, Lydia Sorokin, Emilia Mira, Santos Mañes
Mar 02, 2022
The balance between laminin isoforms containing the α5 or the α4 chain in the endothelial basement membrane determines the site of leukocyte diapedesis under inflammatory conditions. Extracellular superoxide dismutase (SOD3)...
Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines.
Gerard Godoy-Tena, Anis Barmada, Octavio Morante-Palacios, Carlos de la Calle-Fabregat, Ricardo Martins-Ferreira, Anna G Ferreté-Bonastre, Laura Ciudad, Adolfo Ruiz-Sanmartín, Mónica Martínez-Gallo, Ricard Ferrer, Juan Carlos Ruiz-Rodriguez, Javier Rodríguez-Ubreva, Roser Vento-Tormo, Esteban Ballestar
Nov 29, 2022
BACKGROUND: COVID-19 manifests with a wide spectrum of clinical phenotypes, ranging from asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are characterized by marked changes in the myeloid...
Natural variation identifies SNI1, the SMC5/6 component, as a modifier of meiotic crossover in Arabidopsis.
Longfei Zhu, Nadia Fernández-Jiménez, Maja Szymanska-Lejman, Alexandre Pelé, Charles J Underwood, Heïdi Serra, Christophe Lambing, Julia Dluzewska, Tomasz Bieluszewski, Mónica Pradillo, Ian R Henderson, Piotr A Ziolkowski
Sep 13, 2021
The frequency and distribution of meiotic crossovers are tightly controlled; however, variation in this process can be observed both within and between species. Using crosses of two natural Arabidopsis thaliana accessions, Col...
SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.
Stephin J Vervoort, Ana Rita Lourenço, Ana Tufegdzic Vidakovic, Enric Mocholi, José L Sandoval, Oscar M Rueda, Cynthia Frederiks, Cornelieke Pals, Janneke GC Peeters, Carlos Caldas, Alejandra Bruna, Paul J Coffer
Dec 13, 2018
Expression of the transcription factor SOX4 is often elevated in human cancers, where it generally correlates with tumor-progression and poor-disease outcome. Reduction of SOX4 expression results in both diminished...
Highly Water-Soluble Orotic Acid Nanocrystals Produced by High-Energy Milling
Jéssica de Cássia Zaghi Compri, Veni Maria Andres Felli, Felipe Rebello Lourenço, Takayuki Takatsuka, Nikoletta Fotaki, Raimar Löbenberg, Nádia Araci Bou-Chacra, Gabriel Lima Barros de Araujo
May 01, 2019
Orotic acid (OA), a heterocyclic compound also known as vitamin B13, has shown potent antimalarial and cardiac protection activities; however, its limited water solubility has posed a barrier to its use in therapeutic...
Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke.
Raquel Rodríguez-González, Tomás Sobrino, Manuel Rodríguez-Yáñez, Mónica Millán, David Brea, Elena Miranda, Octavio Moldes, Juan Pérez, David A Lomas, Rogelio Leira, Antoni Dávalos, José Castillo
Jun 13, 2011
BACKGROUND: Neuroserpin has shown neuroprotective effects in animal models of cerebral ischemia and has been associated with functional outcome after ischemic stroke. Our aim was to study whether neuroserpin serum levels could...
Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines.
Gerard Godoy-Tena, Anis Barmada, Octavio Morante-Palacios, Carlos de la Calle-Fabregat, Ricardo Martins-Ferreira, Anna G Ferreté-Bonastre, Laura Ciudad, Adolfo Ruiz-Sanmartín, Mónica Martínez-Gallo, Ricard Ferrer, Juan Carlos Ruiz-Rodriguez, Javier Rodríguez-Ubreva, Roser Vento-Tormo, Esteban Ballestar
Jan 04, 2023
BACKGROUND: COVID-19 manifests with a wide spectrum of clinical phenotypes, ranging from asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are characterized by marked changes in the myeloid...
Highly Water-Soluble Orotic Acid Nanocrystals Produced by High-Energy Milling
Jéssica de Cássia Zaghi Compri, Veni Maria Andres Felli, Felipe Rebello Lourenço, Takayuki Takatsuka, Nikoletta Fotaki, Raimar Löbenberg, Nádia Araci Bou-Chacra, Gabriel Lima Barros de Araujo
May 01, 2019
Orotic acid (OA), a heterocyclic compound also known as vitamin B13, has shown potent antimalarial and cardiac protection activities; however, its limited water solubility has posed a barrier to its use in therapeutic...
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