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E-Service Quality and Trust on Customer's Patronage Intention: Moderation Effect of Adoption of Advanced Technologies
The extensive development of electronic gadgets along with technology-oriented communication tools has created a significant impact on the realm of online retail banking transactions. In Bangladesh, online retail banking can...
Published by: IGI Global Scientific Publishing
Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Sadam Yaseen, Gregory Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L Wood, W Jason Cummings, Larry W Tjoelker, Teizo Fujita, Steven Sacks, Peter Garred, Peter Andrew, Robert B Sim, Peter J Lachmann, Russell Wallis, Nicholas Lynch, Wilhelm J Schwaeble
Aug 05, 2019
All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement...
The Patterned Structure of Galactoglucomannan Suggests It May Bind to Cellulose in Seed Mucilage.
Li Yu, Jan J Lyczakowski, Caroline S Pereira, Toshihisa Kotake, Xiaolan Yu, An Li, Soren Mogelsvang, Munir S Skaf, Paul Dupree
Nov 13, 2018
The interaction between mannan polysaccharides and cellulose microfibrils contributes to cell wall properties in some vascular plants, but the molecular arrangement of mannan in the cell wall and the nature of the molecular...
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Franca Orsini, Elvina Chrysanthou, Thomas Dudler, W Jason Cummings, Minoru Takahashi, Teizo Fujita, Gregory Demopulos, Maria-Grazia De Simoni, Wilhelm Schwaeble
Apr 12, 2019
BACKGROUND: Complement activation via the lectin activation pathway (LP) has been identified as the key mechanism behind post-ischemic tissue inflammation causing ischemia-reperfusion injury (IRI) which can significantly impact...
Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins
The mouse (m) DC-SIGN family consists of several homologous type II transmembrane proteins located in close proximity on chromosome 8 and having a single carboxyl terminal carbohydrate recognition domain. We first used...
Published by: Rockefeller University
NG Forouhi, RK Menon, SJ Sharp, N Mannan, PM Timms, AR Martineau, AP Rickard, BJ Boucher, TA Chowdhury, CJ Griffiths, SE Greenwald, SJ Griffin, GA Hitman
Jan 08, 2016
intervention placebo pulse wave velocity randomized trial Type 2 diabetes vitamin D2 vitamin D3 25-Hydroxyvitamin D 2 Adult Aged Calcifediol Cardiovascular Diseases Cholecalciferol Cohort Studies Diabetes mellitus Type 2 Dietary Supplements Double-Blind Method England Ergocalciferols Feasibility Studies Female Follow-Up Studies Glycated Hemoglobin Humans Male Middle Aged Pulse Wave Analysis risk Vascular Stiffness
Multicolor 3D-dSTORM Reveals Native-State Ultrastructure of Polysaccharides' Network during Plant Cell Wall Assembly.
The plant cell wall, a form of the extracellular matrix, is a complex and dynamic network of polymers mediating a plethora of physiological functions. How polysaccharides assemble into a coherent and heterogeneous matrix remains...
Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health
Varun Warrier, Alex SF Kwong, Mannan Luo, Shareefa Dalvie, Jazz Croft, Hannah M Sallis, Jessie Baldwin, Marcus R Munafò, Caroline M Nievergelt, Andrew J Grant, Stephen Burgess, Tyler M Moore, Ran Barzilay, Andrew McIntosh, Marinus H van IJzendoorn, Charlotte AM Cecil
Dec 21, 2020
Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria
SIGNR1, a member of a new family of mouse C-type lectins, is expressed at high levels in macrophages (M?) within the splenic marginal zone, lymph node medulla, and in some strains, in peritoneal cavity. We previously reported...
Published by: Rockefeller University
Accelerating functional gene discovery in osteoarthritis.
Natalie C Butterfield, Katherine F Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S Mannan, Anne-Tounsia Adoum, Victoria D Leitch, John G Logan, Julian A Waung, Elena Ghirardello, Lorraine Southam, Scott E Youlten, J Mark Wilkinson, Elizabeth A McAninch, Valerie E Vancollie, Fiona Kussy, Jacqueline K White, Christopher J Lelliott, David J Adams, Richard Jacques, Antonio C Bianco, Alan Boyde, Eleftheria Zeggini, Peter I Croucher, Graham R Williams, JH Duncan Bassett
Feb 04, 2021
Osteoarthritis causes debilitating pain and disability, resulting in a considerable socioeconomic burden, yet no drugs are available that prevent disease onset or progression. Here, we develop, validate and use rapid-throughput...
Cartilage Bone and Bones Animals Mice Knockout Mice Osteoarthritis Disease Models Animal Genetic Predisposition to Disease Iodide Peroxidase Phenotype Paired Box Transcription Factors Gonadotropin-Releasing Hormone Drug Discovery Genetic Association Studies CRISPR-Cas Systems Clustered Regularly Interspaced Short Palindromic Repeats Gene Editing
Use of Disease-Modifying Therapies in Pediatric Relapsing-Remitting Multiple Sclerosis in the United Kingdom.
Omar A Abdel-Mannan, Celeste Manchoon, Thomas Rossor, Justine-Clair Southin, Carmen Tur, Wallace Brownlee, Susan Byrne, Manali Chitre, Alasdair Coles, Rob Forsyth, Rachel Kneen, Kshitij Mankad, Dipak Ram, Siobhan West, Sukhvir Wright, Evangeline Wassmer, Ming Lim, Olga Ciccarelli, Cheryl Hemingway, Yael Hacohen, UK-Childhood Inflammatory Disease Network
Jun 14, 2021
OBJECTIVES: To compare the real-world effectiveness of newer disease-modifying therapies (DMTs) vs injectables in children with relapsing-remitting multiple sclerosis (RRMS). METHODS: In this retrospective, multicenter study...
An atlas of genetic influences on osteoporosis in humans and mice.
John A Morris, John P Kemp, Scott E Youlten, Laetitia Laurent, John G Logan, Ryan C Chai, Nicholas A Vulpescu, Vincenzo Forgetta, Aaron Kleinman, Sindhu T Mohanty, C Marcelo Sergio, Julian Quinn, Loan Nguyen-Yamamoto, Aimee-Lee Luco, Jinchu Vijay, Marie-Michelle Simon, Albena Pramatarova, Carolina Medina-Gomez, Katerina Trajanoska, Elena J Ghirardello, Natalie C Butterfield, Katharine F Curry, Victoria D Leitch, Penny C Sparkes, Anne-Tounsia Adoum, Naila S Mannan, Davide SK Komla-Ebri, Andrea S Pollard, Hannah F Dewhurst, Thomas AD Hassall, Michael-John G Beltejar, 23andMe Research Team, Douglas J Adams, Suzanne M Vaillancourt, Stephen Kaptoge, Paul Baldock, Cyrus Cooper, Jonathan Reeve, Evangelia E Ntzani, Evangelos Evangelou, Claes Ohlsson, David Karasik, Fernando Rivadeneira, Douglas P Kiel, Jonathan H Tobias, Celia L Gregson, Nicholas C Harvey, Elin Grundberg, David Goltzman, David J Adams, Christopher J Lelliott, David A Hinds, Cheryl L Ackert-Bicknell, Yi-Hsiang Hsu, Matthew T Maurano, Peter I Croucher, Graham R Williams, JH Duncan Bassett, David M Evans, J Brent Richards
Jul 16, 2019
Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative ultrasound in 426,824 individuals, identifying 518...