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Results: 39
Cutting through complexity
Anna Spathis, Julie Burkin, Catherine Moffat, Rachel Tuffnell, Stephen Barclay, Jonathan Mant, Sara Booth
May 10, 2021
Abstract: Chronic breathlessness is a distressing symptom that is challenging to manage. The Breathing, Thinking, Functioning clinical model is an educational tool developed to support breathlessness management. Health...
Cutting through complexity
Anna Spathis, Julie Burkin, Catherine Moffat, Rachel Tuffnell, Stephen Barclay, Jonathan Mant, Sara Booth
May 13, 2021
Chronic breathlessness is a distressing symptom that is challenging to manage. The Breathing, Thinking, Functioning clinical model is an educational tool developed to support breathlessness management. Health professionals...
Coordinated Observations of 8- and 6-hr Tides in the Mesosphere and Lower Thermosphere by Three Meteor Radars Near 60<sup>°</sup>S Latitude
Guiping Liu, Diego Janches, Ruth S. Lieberman, Tracy Moffat-Griffin, David C. Fritts, Nicholas J. Mitchell
Jan 16, 2020
Atmospheric 8- and 6-hr tides are observed for the first time in the zonal and meridional winds at ~82–97 km altitudes simultaneously at Tierra del Fuego (TDF; 53.7°S, 67.7°W), King Edward Point (KEP; 54.3°S, 36.5°W), and...
The Breathing, Thinking, Functioning clinical model
Anna Spathis, Sara Booth, Catherine Moffat, Rhys Hurst, Richella Ryan, Chloe Chin, Julie Burkin
Dec 19, 2018
Refractory breathlessness is a highly prevalent and distressing symptom in advanced chronic respiratory disease. Its intensity is not reliably predicted by the severity of lung pathology, with unhelpful emotions and behaviours...
Winds and tides of the Extended Unified Model in the mesosphere and lower thermosphere validated with meteor radar observations
Matthew J. Griffith, Shaun M. Dempsey, David R. Jackson, Tracy Moffat-Griffin, Nicholas J. Mitchell
Jun 10, 2021
The mesosphere and lower thermosphere (MLT) is a critical region that must be accurately reproduced in general circulation models (GCMs) that aim to include the coupling between the lower and middle atmosphere and the...
/dk/atira/pure/subjectarea/asjc/3100/3103 name=Astronomy and Astrophysics /dk/atira/pure/subjectarea/asjc/1900/1907 name=Geology /dk/atira/pure/subjectarea/asjc/1900/1902 name=Atmospheric Science /dk/atira/pure/subjectarea/asjc/1900/1901 name=Earth and Planetary Sciences (miscellaneous) /dk/atira/pure/subjectarea/asjc/1900/1912 name=Space and Planetary Science /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
Cutting through complexity
Anna Spathis, Julie Burkin, Catherine Moffat, Rachel Tuffnell, Stephen Barclay, Jonathan Mant, Sara Booth
Jun 11, 2021
Chronic breathlessness is a distressing symptom that is challenging to manage. The Breathing, Thinking, Functioning clinical model is an educational tool developed to support breathlessness management. Health professionals...
Published by: NPJ primary care respiratory medicine
Winds and tides of the Extended Unified Model in the mesosphere and lower thermosphere validated with meteor radar observations
Matthew J. Griffith, Shaun M. Dempsey, David R. Jackson, Tracy Moffat-Griffin, Nicholas J. Mitchell
Jun 10, 2021
The mesosphere and lower thermosphere (MLT) is a critical region that must be accurately reproduced in general circulation models (GCMs) that aim to include the coupling between the lower and middle atmosphere and the...
/dk/atira/pure/subjectarea/asjc/3100/3103 name=Astronomy and Astrophysics /dk/atira/pure/subjectarea/asjc/1900/1907 name=Geology /dk/atira/pure/subjectarea/asjc/1900/1902 name=Atmospheric Science /dk/atira/pure/subjectarea/asjc/1900/1901 name=Earth and Planetary Sciences (miscellaneous) /dk/atira/pure/subjectarea/asjc/1900/1912 name=Space and Planetary Science /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
The Effect of Heat Treatment on the Oxidation Resistance of Cobalt-Based Superalloys
Degradation of the mechanical integrity of cobalt-based superalloys can occur as the carbide network is progressively oxidised during high temperature service. In this study, a heat-treatment aimed at redistributing the carbides...
Time dependent decomposition of ammonia borane for the controlled production of 2D hexagonal boron nitride.
Vitaliy Babenko, George Lane, Antal A Koos, Adrian T Murdock, Karwei So, Jude Britton, Seyyed Shayan Meysami, Jonathan Moffat, Nicole Grobert
Jan 24, 2018
Ammonia borane (AB) is among the most promising precursors for the large-scale synthesis of hexagonal boron nitride (h-BN) by chemical vapour deposition (CVD). Its non-toxic and non-flammable properties make AB particularly...
Winds and tides of the Antarctic mesosphere and lower thermosphere
Shaun Dempsey, Neil Hindley, Tracy Moffat-Griffin, Corwin Wright, Anne K. Smith, Jian Du, Nicholas J. Mitchell
Jan 31, 2021
Atmospheric tides play a critical role in the dynamics and coupling of mesosphere and lower-thermosphere (MLT). Global Circulation Models (GCMs) that aim to span the lower, middle and upper atmosphere must therefore be capable...
Epilepsy, cognitive deficits and neuroanatomy in males with ZDHHC9 mutations.
Kate Baker, Duncan E Astle, Gaia Scerif, Jessica Barnes, Jennie Smith, Georgina Moffat, Jonathan Gillard, Torsten Baldeweg, F Lucy Raymond
May 20, 2015
1109 Neurosciences Clinical Clinical Medicine and Science Basic Behavioral and Social Science Neurosciences Neurodegenerative Genetics Clinical Research Intellectual and Developmental Disabilities (IDD) Brain Disorders Behavioral and Social Science Mental Health Epilepsy Neurological Mental Health 2.1 Biological and endogenous factors
Winds and tides of the Antarctic mesosphere and lower thermosphere
Shaun Dempsey, Neil Hindley, Tracy Moffat-Griffin, Corwin Wright, Anne K. Smith, Jian Du, Nicholas J. Mitchell
Jan 31, 2021
Atmospheric tides play a critical role in the dynamics and coupling of mesosphere and lower-thermosphere (MLT). Global Circulation Models (GCMs) that aim to span the lower, middle and upper atmosphere must therefore be capable...
Coordinated Observations of 8- and 6-hr Tides in the Mesosphere and Lower Thermosphere by Three Meteor Radars Near 60<sup>°</sup>S Latitude
Guiping Liu, Diego Janches, Ruth S. Lieberman, Tracy Moffat-Griffin, David C. Fritts, Nicholas J. Mitchell
Jan 16, 2020
Atmospheric 8- and 6-hr tides are observed for the first time in the zonal and meridional winds at ~82–97 km altitudes simultaneously at Tierra del Fuego (TDF; 53.7°S, 67.7°W), King Edward Point (KEP; 54.3°S, 36.5°W), and...
Genetic analysis of wheat sensitivity to the ToxB fungal effector from Pyrenophora tritici-repentis, the causal agent of tan spot.
Beatrice Corsi, Lawrence Percival-Alwyn, Rowena C Downie, Luca Venturini, Elyce M Iagallo, Camila Campos Mantello, Charlie McCormick-Barnes, Pao Theen See, Richard P Oliver, Caroline S Moffat, James Cockram
Jan 07, 2021
Genetic mapping of sensitivity to the Pyrenophora tritici-repentis effector ToxB allowed development of a diagnostic genetic marker, and investigation of wheat pedigrees allowed transmission of sensitive alleles to be tracked....
Establishing population-based surveillance of diagnostic timeliness using linked cancer registry and administrative data for patients with colorectal and lung cancer.
Clare Pearson, Jess Fraser, Michael Peake, Roland Valori, Veronique Poirier, Victoria H Coupland, Sara Hiom, Sean McPhail, Jodie Moffat, Georgios Lyratzopoulos, Jon Shelton
Sep 17, 2019
Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations.
Shane A Norris, Abdallah Daar, Dorairajan Balasubramanian, Peter Byass, Elizabeth Kimani-Murage, Andrew Macnab, Christoff Pauw, Atul Singhal, Chittaranjan Yajnik, James Akazili, Naomi Levitt, Jihene Maatoug, Nolwazi Mkhwanazi, Sophie E Moore, Moffat Nyirenda, Juliet RC Pulliam, Tamsen Rochat, Rihlat Said-Mohamed, Soraya Seedat, Eugene Sobngwi, Mark Tomlinson, Elona Toska, Cari van Schalkwyk
Jan 21, 2020
Data from many high- and low- or middle-income countries have linked exposures during key developmental periods (in particular pregnancy and infancy) to later health and disease. Africa faces substantial challenges with...
Africa Sustainable Development Goals (SDGs) developmental origins of health and disease (DOHaD) Life course epidemiology Non-communicable disease Policy Africa Conservation of Natural Resources Female Humans Noncommunicable Diseases Pregnancy PREVENTIVE MEDICINE Public Health
Published by: Glob Health Action
Genetic analysis of wheat sensitivity to the ToxB fungal effector from Pyrenophora tritici-repentis, the causal agent of tan spot
Beatrice Corsi, Lawrence Percival-Alwyn, Rowena C. Downie, Luca Venturini, Elyce M. Iagallo, Camila Campos Mantello, Charlie McCormick-Barnes, Pao Theen See, Richard P. Oliver, Caroline S. Moffat, James Cockram
Jun 06, 2020
Abstract: Key message: Genetic mapping of sensitivity to the Pyrenophora tritici-repentis effector ToxB allowed development of a diagnostic genetic marker, and investigation of wheat pedigrees allowed transmission of sensitive...
Transferability of genetic risk scores in African populations.
Abram B Kamiza, Sounkou M Toure, Marijana Vujkovic, Tafadzwa Machipisa, Opeyemi S Soremekun, Christopher Kintu, Manuel Corpas, Fraser Pirie, Elizabeth Young, Dipender Gill, Manjinder S Sandhu, Pontiano Kaleebu, Moffat Nyirenda, Ayesha A Motala, Tinashe Chikowore, Segun Fatumo
Jun 17, 2022
The poor transferability of genetic risk scores (GRSs) derived from European ancestry data in diverse populations is a cause of concern. We set out to evaluate whether GRSs derived from data of African American individuals and...
Addressing unmet needs in understanding asthma mechanisms
Michael Edwards, Sejal Saglani, Jurgen Schwarze, Chrysanthi Skevaki, Jaclyn Smith, Ben Ainsworth, Mark Almond, Evangelos Andreakos, Maria Belvisi, Kian Fan Chung, William Cookson, Paul Cullinan, Catherine Hawrylowicz, Marek Lommatzsch, David Jackson, Rene Lutter, Benjamin Marsland, Miriam Moffat, Mike Thomas, J. Christian Virchow, Georgina Xanthou, Jessica Edwards, Samantha Walker, Sebastian L. Johnston, EARIP WP2 Working Group
May 01, 2017
Asthma is a heterogeneous, complex disease with clinical phenotypes that incorporate persistent symptoms and acute exacerbations. It affects many millions of Europeans throughout their education and working lives and puts a...
Lipid traits and type 2 diabetes risk in African ancestry individuals
Opeyemi Soremekun, Ville Karhunen, Yiyan He, Skanda Rajasundaram, Bowen Liu, Apostolos Gkatzionis, Chisom Soremekun, Brenda Udosen, Hanan Musa, Sarah Silva, Christopher Kintu, Richard Mayanja, Mariam Nakabuye, Tafadzwa Machipisa, Amy Mason, Marijana Vujkovic, Verena Zuber, Mahmoud Soliman, Joseph Mugisha, Oyekanmi Nash, Pontiano Kaleebu, Moffat Nyirenda, Tinashe Chikowore, Dorothea Nitsch, Stephen Burgess, Dipender Gill, Segun Fatumo
Apr 24, 2022
BACKGROUND: Dyslipidaemia is highly prevalent in individuals with type 2 diabetes mellitus (T2DM). Numerous studies have sought to disentangle the causal relationship between dyslipidaemia and T2DM liability. However...
Transferability of genetic risk scores in African populations.
Abram B Kamiza, Sounkou M Toure, Marijana Vujkovic, Tafadzwa Machipisa, Opeyemi S Soremekun, Christopher Kintu, Manuel Corpas, Fraser Pirie, Elizabeth Young, Dipender Gill, Manjinder S Sandhu, Pontiano Kaleebu, Moffat Nyirenda, Ayesha A Motala, Tinashe Chikowore, Segun Fatumo
Jun 18, 2022
The poor transferability of genetic risk scores (GRSs) derived from European ancestry data in diverse populations is a cause of concern. We set out to evaluate whether GRSs derived from data of African American individuals and...
Transferability of genetic risk scores in African populations.
Abram B Kamiza, Sounkou M Toure, Marijana Vujkovic, Tafadzwa Machipisa, Opeyemi S Soremekun, Christopher Kintu, Manuel Corpas, Fraser Pirie, Elizabeth Young, Dipender Gill, Manjinder S Sandhu, Pontiano Kaleebu, Moffat Nyirenda, Ayesha A Motala, Tinashe Chikowore, Segun Fatumo
Jul 03, 2022
The poor transferability of genetic risk scores (GRSs) derived from European ancestry data in diverse populations is a cause of concern. We set out to evaluate whether GRSs derived from data of African American individuals and...
Regulatory T cells promote myelin regeneration in the central nervous system
Y Dombrowski, T O'Hagan, M Dittmer, R Penalva, SR Mayoral, P Bankhead, S Fleville, G Eleftheriadis, C Zhao, M Naughton, R Hassan, J Moffat, J Falconer, A Boyd, P Hamilton, IV Allen, A Kissenpfennig, PN Moynagh, E Evergren, B Perbal, AC Williams, RJ Ingram, JR Chan, RJM Franklin, DC Fitzgerald
Apr 27, 2017
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48
SP Jackson, Georgia Velimezi, Lydia Robinson-Garcia, Francisco Muñoz-Martínez, Wouter Wiegant, Joana Ferreira da Silva, Michel Owusu, Martin Moder, Marc Wiedner, Sara Rosenthal, Kathleen Fisch, Jason Moffat, Jörg Menche, Haico Van Attikum, Joanna Loizou
Sep 25, 2018
Defects in DNA repair can cause various genetic diseases with severe pathological phenotypes. Fanconi anemia (FA) is a rare disease characterized by bone marrow failure, developmental abnormalities and increased cancer risk that...
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