Search
Results: 30
Application-Specific Discriminant Analysis of Cardiac Anomalies Using Shift-Invariant Wavelet Transform
Automatic arrhythmia detection in electrocardiogram (ECG) using supervised learning has gained significant considerations in recent years. This paper projects the performance analysis of classifiers such as support vector...
Published by: IGI Global Scientific Publishing
Synthesis of ZrO2 Based Nanofluids for Cooling and Insulation of Transformers
Nanofluids have recently emerged as an important new technology for heat transfer in various engineering applications. In this work, zirconia nanoparticles (ZrO2) were synthesized using a microwave-assisted sol-gel method for...
Does the Choice of Metric Matter for Identifying Areas for Policy Priority? An Empirical Assessment Using Child Undernutrition in India
Abstract Ratio-based prevalence and absolute headcounts are the two most commonly accepted metrics to measure the burden of various socioeconomic phenomenon. However, ratio-based prevalence...
Effects of ZnO and SiO<sub>2</sub> Nanoparticle Additions on the Structural, Water Absorption and Mechanical Properties of Polyvinyl Alcohol (PVA) Films
Nanocomposite films were prepared with polyvinyl alcohol (PVA) as a base matrix and ZnO, SiO2 nanoparticles as a filler material. SiO2 and ZnO nanoparticles were synthesized using solgel and co-precipitation methods...
Role of Fe (x=0-0.15) Substitution on Structural, Magnetic, and Transport Properties of the La0.7Sr0.3FexMn1-xO3 System
This paper investigates the effect of Fe substitution on the structural, magnetic and transport properties of the La0.7Sr0.3MnxFe1-xO3 (LSMO) system where x ranged between 0 and 0.15. Samples were prepared using a non-aqueous...
Synthesis of ZrO2 Based Nanofluids for Cooling and Insulation of Transformers
Nanofluids have recently emerged as an important new technology for heat transfer in various engineering applications. In this work, zirconia nanoparticles (ZrO2) were synthesized using a microwave-assisted sol-gel method for...
Does the Choice of Metric Matter for Identifying Areas for Policy Priority? An Empirical Assessment Using Child Undernutrition in India
Abstract: Ratio-based prevalence and absolute headcounts are the two most commonly accepted metrics to measure the burden of various socioeconomic phenomenon. However, ratio-based prevalence, calculated as the number of cases...
Effects of ZnO and SiO<sub>2</sub> Nanoparticle Additions on the Structural, Water Absorption and Mechanical Properties of Polyvinyl Alcohol (PVA) Films
Nanocomposite films were prepared with polyvinyl alcohol (PVA) as a base matrix and ZnO, SiO2 nanoparticles as a filler material. SiO2 and ZnO nanoparticles were synthesized using solgel and co-precipitation methods...
Role of Fe (x=0-0.15) Substitution on Structural, Magnetic, and Transport Properties of the La0.7Sr0.3FexMn1-xO3 System
This paper investigates the effect of Fe substitution on the structural, magnetic and transport properties of the La0.7Sr0.3MnxFe1-xO3 (LSMO) system where x ranged between 0 and 0.15. Samples were prepared using a non-aqueous...
Clinical Pharmacokinetics, Safety, and Tolerability of a Novel, First-in-Class TRPV4 Ion Channel Inhibitor, GSK2798745, in Healthy and Heart Failure Subjects.
Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis.
Substance, use in relation to COVID-19
Navin Kumar, Kamila Janmohamed, Kate Nyhan, Silvia S. Martins, Magdalena Cerda, Deborah Hasin, Jenny Scott, Afia Sarpong Frimpong, Richard Pates, Lilian A. Ghandour, Mayyada Wazaify, Kaveh Khoshnood
Apr 30, 2022
Background: We conducted a scoping review focused on various forms of substance use amid the pandemic, looking at both the impact of substance use on COVID-19 infection, severity, and vaccine uptake, as well as the impact...
Epigenetic resetting in the human germ line entails histone modification remodeling.
Wolfram H Gruhn, Walfred WC Tang, Sabine Dietmann, João P Alves-Lopes, Christopher A Penfold, Frederick CK Wong, Navin B Ramakrishna, M Azim Surani
Feb 19, 2023
Epigenetic resetting in the mammalian germ line entails acute DNA demethylation, which lays the foundation for gametogenesis, totipotency, and embryonic development. We characterize the epigenome of hypomethylated human...
Substance, use in relation to COVID-19
Navin Kumar, Kamila Janmohamed, Kate Nyhan, Silvia S. Martins, Magdalena Cerda, Deborah Hasin, Jenny Scott, Afia Sarpong Frimpong, Richard Pates, Lilian A. Ghandour, Mayyada Wazaify, Kaveh Khoshnood
Apr 30, 2022
Background: We conducted a scoping review focused on various forms of substance use amid the pandemic, looking at both the impact of substance use on COVID-19 infection, severity, and vaccine uptake, as well as the impact...
Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor.
Aili L Lazaar, Lucy Yang, Rebecca L Boardley, Navin S Goyal, Jonathan Robertson, Sandra J Baldwin, David E Newby, Ian B Wilkinson, Ruth Tal-Singer, Ruth J Mayer, Joseph Cheriyan
May 04, 2016
COPD CLINICAL PHARMACOLOGY clinical trial Smoking soluble epoxide hydrolase 8 11 14-Eicosatrienoic Acid Adolescent Adult Aged Cohort Studies Cross-Over Studies Cyclohexylamines Dermatitis Contact Double-Blind Method Enzyme Inhibitors Epoxide Hydrolases Female Half-Life Headache Healthy Volunteers Humans Male Middle Aged obesity Triazines Young Adult
How Social Considerations Improve the Equity and Effectiveness of Ecosystem Restoration.
Sara Löfqvist, Fritz Kleinschroth, Adia Bey, Ariane de Bremond, Ruth DeFries, Jinwei Dong, Forrest Fleischman, Sharachchandra Lele, Dominic A Martin, Peter Messerli, Patrick Meyfroidt, Marion Pfeifer, Sarobidy O Rakotonarivo, Navin Ramankutty, Vijay Ramprasad, Pushpendra Rana, Jeanine M Rhemtulla, Casey M Ryan, Ima Célia Guimarães Vieira, Geoff J Wells, Rachael D Garrett
Apr 09, 2023
Ecosystem restoration is an important means to address global sustainability challenges. However, scientific and policy discourse often overlooks the social processes that influence the equity and effectiveness of restoration...
social justice Climate Change Mitigation Land use management Restoration Longevity Restoration Policy
Published by: Bioscience
DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes.
Atish Kizhakeyil, Nurmahirah Binte Mohammed Zaini, Zhi Sheng Poh, Brandon Han Siang Wong, Xinpeng Loh, Aik Seng Ng, Zun Siong Low, Praseetha Prasannan, Chun Gong, Michelle Guet Khim Tan, Chandramouli Nagarajan, Dachuan Huang, Pang Wan Lu, Jing Quan Lim, Sharon Barrans, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, George Follows, Daniel J Hodson, Ming Qing Du, Yeow Tee Goh, Suat Hoon Tan, Nicholas Francis Grigoropoulos, Navin Kumar Verma
Oct 22, 2021
DDX3X mutation Drug Resistance Hematolymphoid malignancy Prognosis Tumour metastasis Antineoplastic Agents Biomarkers Tumor Cell Line Tumor Cyclin D1 DEAD-box RNA Helicases Disease Progression Drug Resistance Neoplasm Humans Lymphoma Large B-Cell Diffuse Lymphoma Non-Hodgkin Mitogen-Activated Protein Kinases Mutation Prognosis STAT3 Transcription Factor Exome Sequencing
Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.
Esther H Lips, Tapsi Kumar, Anargyros Megalios, Lindy L Visser, Michael Sheinman, Angelo Fortunato, Vandna Shah, Marlous Hoogstraat, Emi Sei, Diego Mallo, Maria Roman-Escorza, Ahmed A Ahmed, Mingchu Xu, Alexandra W van den Belt-Dusebout, Wim Brugman, Anna K Casasent, Karen Clements, Helen R Davies, Liping Fu, Anita Grigoriadis, Timothy M Hardman, Lorraine M King, Marielle Krete, Petra Kristel, Michiel de Maaker, Carlo C Maley, Jeffrey R Marks, Brian A Menegaz, Lennart Mulder, Frank Nieboer, Salpie Nowinski, Sarah Pinder, Jelmar Quist, Carolina Salinas-Souza, Michael Schaapveld, Marjanka K Schmidt, Abeer M Shaaban, Rana Shami, Mathini Sridharan, John Zhang, Hilary Stobart, Deborah Collyar, Serena Nik-Zainal, Lodewyk FA Wessels, E Shelley Hwang, Nicholas E Navin, P Andrew Futreal, Grand Challenge PRECISION consortium, Alastair M Thompson, Jelle Wesseling, Elinor J Sawyer
Jul 10, 2022
Ductal carcinoma in situ (DCIS) is the most common form of preinvasive breast cancer and, despite treatment, a small fraction (5-10%) of DCIS patients develop subsequent invasive disease. A fundamental biologic question is...
Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.
Esther H Lips, Tapsi Kumar, Anargyros Megalios, Lindy L Visser, Michael Sheinman, Angelo Fortunato, Vandna Shah, Marlous Hoogstraat, Emi Sei, Diego Mallo, Maria Roman-Escorza, Ahmed A Ahmed, Mingchu Xu, Alexandra W van den Belt-Dusebout, Wim Brugman, Anna K Casasent, Karen Clements, Helen R Davies, Liping Fu, Anita Grigoriadis, Timothy M Hardman, Lorraine M King, Marielle Krete, Petra Kristel, Michiel de Maaker, Carlo C Maley, Jeffrey R Marks, Brian A Menegaz, Lennart Mulder, Frank Nieboer, Salpie Nowinski, Sarah Pinder, Jelmar Quist, Carolina Salinas-Souza, Michael Schaapveld, Marjanka K Schmidt, Abeer M Shaaban, Rana Shami, Mathini Sridharan, John Zhang, Hilary Stobart, Deborah Collyar, Serena Nik-Zainal, Lodewyk FA Wessels, E Shelley Hwang, Nicholas E Navin, P Andrew Futreal, Grand Challenge PRECISION consortium, Alastair M Thompson, Jelle Wesseling, Elinor J Sawyer
Jun 14, 2022
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
SM Willems, DJ Wright, FR Day, K Trajanoska, PK Joshi, JA Morris, AM Matteini, FC Garton, N Grarup, N Oskolkov, A Thalamuthu, M Mangino, J Liu, A Demirkan, M Lek, L Xu, G Wang, C Oldmeadow, KJ Gaulton, LA Lotta, E Miyamoto-Mikami, MA Rivas, T White, P-R Loh, M Aadahl, N Amin, JR Attia, K Austin, B Benyamin, S Brage, Y-C Cheng, P Cięszczyk, W Derave, K-F Eriksson, N Eynon, A Linneberg, A Lucia, M Massidda, BD Mitchell, M Miyachi, H Murakami, S Padmanabhan, A Pandey, I Papadimitriou, DK Rajpal, C Sale, TM Schnurr, F Sessa, N Shrine, MD Tobin, I Varley, LV Wain, NR Wray, CM Lindgren, DG MacArthur, D Waterworth, MI McCarthy, O Pedersen, K-T Khaw, DP Kiel, Y Pitsiladis, N Fuku, PW Franks, KN North, CM van Duijn, KA Mather, T Hansen, O Hansson, T Spector, JM Murabito, JB Richards, F Rivadeneira, C Langenberg, JRB Perry, NJ Wareham, RA Scott
May 31, 2017
Actins Adult Aged Cohort Studies Female Genetic Loci Genetics Population Genome-Wide Association Study Hand Hand Strength Humans Male Membrane Proteins Middle Aged Neoplasm Proteins Nuclear Proteins Polymorphism Single Nucleotide Repressor Proteins Transforming Growth Factor alpha United Kingdom White People
FinnGen provides genetic insights from a well-phenotyped isolated population
Mitja I. Kurki, Juha Karjalainen, Priit Palta, Timo P. Sipilä, Kati Kristiansson, Kati M. Donner, Mary P. Reeve, Hannele Laivuori, Mervi Aavikko, Mari A. Kaunisto, Anu Loukola, Elisa Lahtela, Hannele Mattsson, Päivi Laiho, Pietro Della Briotta Parolo, Arto A. Lehisto, Masahiro Kanai, Nina Mars, Joel Rämö, Tuomo Kiiskinen, Henrike O. Heyne, Kumar Veerapen, Sina Rüeger, Susanna Lemmelä, Wei Zhou, Sanni Ruotsalainen, Kalle Pärn, Tero Hiekkalinna, Sami Koskelainen, Teemu Paajanen, Vincent Llorens, Javier Gracia-Tabuenca, Harri Siirtola, Kadri Reis, Abdelrahman G. Elnahas, Benjamin Sun, Christopher N. Foley, Katriina Aalto-Setälä, Kaur Alasoo, Mikko Arvas, Kirsi Auro, Shameek Biswas, Argyro Bizaki-Vallaskangas, Olli Carpen, Chia-Yen Chen, Oluwaseun A. Dada, Zhihao Ding, Margaret G. Ehm, Kari Eklund, Martti Färkkilä, Hilary Finucane, Andrea Ganna, Awaisa Ghazal, Robert R. Graham, Eric M. Green, Antti Hakanen, Marco Hautalahti, Åsa K. Hedman, Mikko Hiltunen, Reetta Hinttala, Iiris Hovatta, Xinli Hu, Adriana Huertas-Vazquez, Laura Huilaja, Julie Hunkapiller, Howard Jacob, Jan-Nygaard Jensen, Heikki Joensuu, Sally John, Valtteri Julkunen, Marc Jung, Juhani Junttila, Kai Kaarniranta, Mika Kähönen, Risto Kajanne, Lila Kallio, Reetta Kälviäinen, Jaakko Kaprio, Nurlan Kerimov, Johannes Kettunen, Elina Kilpeläinen, Terhi Kilpi, Katherine Klinger, Veli-Matti Kosma, Teijo Kuopio, Venla Kurra, Triin Laisk, Jari Laukkanen, Nathan Lawless, Aoxing Liu, Simonne Longerich, Reedik Mägi, Johanna Mäkelä, Antti Mäkitie, Anders Malarstig, Arto Mannermaa, Joseph Maranville, Athena Matakidou, Tuomo Meretoja, Sahar V. Mozaffari, Mari E. K. Niemi, Marianna Niemi, Teemu Niiranen, Christopher J. O´Donnell, Ma´en Obeidat, George Okafo, Hanna M. Ollila, Antti Palomäki, Tuula Palotie, Jukka Partanen, Dirk S. Paul, Margit Pelkonen, Rion K. Pendergrass, Slavé Petrovski, Anne Pitkäranta, Adam Platt, David Pulford, Eero Punkka, Pirkko Pussinen, Neha Raghavan, Fedik Rahimov, Deepak Rajpal, Nicole A. Renaud, Bridget Riley-Gillis, Rodosthenis Rodosthenous, Elmo Saarentaus, Aino Salminen, Eveliina Salminen, Veikko Salomaa, Johanna Schleutker, Raisa Serpi, Huei-Yi Shen, Richard Siegel, Kaisa Silander, Sanna Siltanen, Sirpa Soini, Hilkka Soininen, Jae Hoon Sul, Ioanna Tachmazidou, Kaisa Tasanen, Pentti Tienari, Sanna Toppila-Salmi, Taru Tukiainen, Tiinamaija Tuomi, Joni A. Turunen, Jacob C. Ulirsch, Felix Vaura, Petri Virolainen, Jeffrey Waring, Dawn Waterworth, Robert Yang, Mari Nelis, Anu Reigo, Andres Metspalu, Lili Milani, Tõnu Esko, Caroline Fox, Aki S. Havulinna, Markus Perola, Samuli Ripatti, Anu Jalanko, Tarja Laitinen, Tomi P. Mäkelä, Robert Plenge, Mark McCarthy, Heiko Runz, Mark J. Daly, Aarno Palotie
Feb 24, 2023
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived...
FinnGen provides genetic insights from a well-phenotyped isolated population.
Mitja I Kurki, Juha Karjalainen, Priit Palta, Timo P Sipilä, Kati Kristiansson, Kati M Donner, Mary P Reeve, Hannele Laivuori, Mervi Aavikko, Mari A Kaunisto, Anu Loukola, Elisa Lahtela, Hannele Mattsson, Päivi Laiho, Pietro Della Briotta Parolo, Arto A Lehisto, Masahiro Kanai, Nina Mars, Joel Rämö, Tuomo Kiiskinen, Henrike O Heyne, Kumar Veerapen, Sina Rüeger, Susanna Lemmelä, Wei Zhou, Sanni Ruotsalainen, Kalle Pärn, Tero Hiekkalinna, Sami Koskelainen, Teemu Paajanen, Vincent Llorens, Javier Gracia-Tabuenca, Harri Siirtola, Kadri Reis, Abdelrahman G Elnahas, Benjamin Sun, Christopher N Foley, Katriina Aalto-Setälä, Kaur Alasoo, Mikko Arvas, Kirsi Auro, Shameek Biswas, Argyro Bizaki-Vallaskangas, Olli Carpen, Chia-Yen Chen, Oluwaseun A Dada, Zhihao Ding, Margaret G Ehm, Kari Eklund, Martti Färkkilä, Hilary Finucane, Andrea Ganna, Awaisa Ghazal, Robert R Graham, Eric M Green, Antti Hakanen, Marco Hautalahti, Åsa K Hedman, Mikko Hiltunen, Reetta Hinttala, Iiris Hovatta, Xinli Hu, Adriana Huertas-Vazquez, Laura Huilaja, Julie Hunkapiller, Howard Jacob, Jan-Nygaard Jensen, Heikki Joensuu, Sally John, Valtteri Julkunen, Marc Jung, Juhani Junttila, Kai Kaarniranta, Mika Kähönen, Risto Kajanne, Lila Kallio, Reetta Kälviäinen, Jaakko Kaprio, FinnGen, Nurlan Kerimov, Johannes Kettunen, Elina Kilpeläinen, Terhi Kilpi, Katherine Klinger, Veli-Matti Kosma, Teijo Kuopio, Venla Kurra, Triin Laisk, Jari Laukkanen, Nathan Lawless, Aoxing Liu, Simonne Longerich, Reedik Mägi, Johanna Mäkelä, Antti Mäkitie, Anders Malarstig, Arto Mannermaa, Joseph Maranville, Athena Matakidou, Tuomo Meretoja, Sahar V Mozaffari, Mari EK Niemi, Marianna Niemi, Teemu Niiranen, Christopher J O Donnell, Ma En Obeidat, George Okafo, Hanna M Ollila, Antti Palomäki, Tuula Palotie, Jukka Partanen, Dirk S Paul, Margit Pelkonen, Rion K Pendergrass, Slavé Petrovski, Anne Pitkäranta, Adam Platt, David Pulford, Eero Punkka, Pirkko Pussinen, Neha Raghavan, Fedik Rahimov, Deepak Rajpal, Nicole A Renaud, Bridget Riley-Gillis, Rodosthenis Rodosthenous, Elmo Saarentaus, Aino Salminen, Eveliina Salminen, Veikko Salomaa, Johanna Schleutker, Raisa Serpi, Huei-Yi Shen, Richard Siegel, Kaisa Silander, Sanna Siltanen, Sirpa Soini, Hilkka Soininen, Jae Hoon Sul, Ioanna Tachmazidou, Kaisa Tasanen, Pentti Tienari, Sanna Toppila-Salmi, Taru Tukiainen, Tiinamaija Tuomi, Joni A Turunen, Jacob C Ulirsch, Felix Vaura, Petri Virolainen, Jeffrey Waring, Dawn Waterworth, Robert Yang, Mari Nelis, Anu Reigo, Andres Metspalu, Lili Milani, Tõnu Esko, Caroline Fox, Aki S Havulinna, Markus Perola, Samuli Ripatti, Anu Jalanko, Tarja Laitinen, Tomi P Mäkelä, Robert Plenge, Mark McCarthy, Heiko Runz, Mark J Daly, Aarno Palotie
Feb 25, 2023
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived...
FinnGen provides genetic insights from a well-phenotyped isolated population.
Mitja I Kurki, Juha Karjalainen, Priit Palta, Timo P Sipilä, Kati Kristiansson, Kati M Donner, Mary P Reeve, Hannele Laivuori, Mervi Aavikko, Mari A Kaunisto, Anu Loukola, Elisa Lahtela, Hannele Mattsson, Päivi Laiho, Pietro Della Briotta Parolo, Arto A Lehisto, Masahiro Kanai, Nina Mars, Joel Rämö, Tuomo Kiiskinen, Henrike O Heyne, Kumar Veerapen, Sina Rüeger, Susanna Lemmelä, Wei Zhou, Sanni Ruotsalainen, Kalle Pärn, Tero Hiekkalinna, Sami Koskelainen, Teemu Paajanen, Vincent Llorens, Javier Gracia-Tabuenca, Harri Siirtola, Kadri Reis, Abdelrahman G Elnahas, Benjamin Sun, Christopher N Foley, Katriina Aalto-Setälä, Kaur Alasoo, Mikko Arvas, Kirsi Auro, Shameek Biswas, Argyro Bizaki-Vallaskangas, Olli Carpen, Chia-Yen Chen, Oluwaseun A Dada, Zhihao Ding, Margaret G Ehm, Kari Eklund, Martti Färkkilä, Hilary Finucane, Andrea Ganna, Awaisa Ghazal, Robert R Graham, Eric M Green, Antti Hakanen, Marco Hautalahti, Åsa K Hedman, Mikko Hiltunen, Reetta Hinttala, Iiris Hovatta, Xinli Hu, Adriana Huertas-Vazquez, Laura Huilaja, Julie Hunkapiller, Howard Jacob, Jan-Nygaard Jensen, Heikki Joensuu, Sally John, Valtteri Julkunen, Marc Jung, Juhani Junttila, Kai Kaarniranta, Mika Kähönen, Risto Kajanne, Lila Kallio, Reetta Kälviäinen, Jaakko Kaprio, Nurlan Kerimov, Johannes Kettunen, Elina Kilpeläinen, Terhi Kilpi, Katherine Klinger, Veli-Matti Kosma, Teijo Kuopio, Venla Kurra, Triin Laisk, Jari Laukkanen, Nathan Lawless, Aoxing Liu, Simonne Longerich, Reedik Mägi, Johanna Mäkelä, Antti Mäkitie, Anders Malarstig, Arto Mannermaa, Joseph Maranville, Athena Matakidou, Tuomo Meretoja, Sahar V Mozaffari, Mari E K Niemi, Marianna Niemi, Teemu Niiranen, Christopher J O Donnell, Ma En Obeidat, George Okafo, Hanna M Ollila, Antti Palomäki, Tuula Palotie, Jukka Partanen, Dirk S Paul, Margit Pelkonen, Rion K Pendergrass, Slavé Petrovski, Anne Pitkäranta, Adam Platt, David Pulford, Eero Punkka, Pirkko Pussinen, Neha Raghavan, Fedik Rahimov, Deepak Rajpal, Nicole A Renaud, Bridget Riley-Gillis, Rodosthenis Rodosthenous, Elmo Saarentaus, Aino Salminen, Eveliina Salminen, Veikko Salomaa, Johanna Schleutker, Raisa Serpi, Huei-Yi Shen, Richard Siegel, Kaisa Silander, Sanna Siltanen, Sirpa Soini, Hilkka Soininen, Jae Hoon Sul, Ioanna Tachmazidou, Kaisa Tasanen, Pentti Tienari, Sanna Toppila-Salmi, Taru Tukiainen, Tiinamaija Tuomi, Joni A Turunen, Jacob C Ulirsch, Felix Vaura, Petri Virolainen, Jeffrey Waring, Dawn Waterworth, Robert Yang, Mari Nelis, Anu Reigo, Andres Metspalu, Lili Milani, Tõnu Esko, Caroline Fox, Aki S Havulinna, Markus Perola, Samuli Ripatti, Anu Jalanko, Tarja Laitinen, Tomi P Mäkelä, Robert Plenge, Mark McCarthy, Heiko Runz, Mark J Daly, Aarno Palotie
Feb 19, 2023
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived...
Humans Disease Genetic Predisposition to Disease Gene Frequency Phenotype Middle Aged Estonia Finland Meta-Analysis as Topic Genome-Wide Association Study United Kingdom White People
Published by: Nature
FinnGen provides genetic insights from a well-phenotyped isolated population
Mitja I. Kurki, Juha Karjalainen, Priit Palta, Timo P. Sipilä, Kati Kristiansson, Kati M. Donner, Mary P. Reeve, Hannele Laivuori, Mervi Aavikko, Mari A. Kaunisto, Anu Loukola, Elisa Lahtela, Hannele Mattsson, Päivi Laiho, Pietro Della Briotta Parolo, Arto A. Lehisto, Masahiro Kanai, Nina Mars, Joel Rämö, Tuomo Kiiskinen, Henrike O. Heyne, Kumar Veerapen, Sina Rüeger, Susanna Lemmelä, Wei Zhou, Sanni Ruotsalainen, Kalle Pärn, Tero Hiekkalinna, Sami Koskelainen, Teemu Paajanen, Vincent Llorens, Javier Gracia-Tabuenca, Harri Siirtola, Kadri Reis, Abdelrahman G. Elnahas, Benjamin Sun, Christopher N. Foley, Katriina Aalto-Setälä, Kaur Alasoo, Mikko Arvas, Kirsi Auro, Shameek Biswas, Argyro Bizaki-Vallaskangas, Olli Carpen, Chia-Yen Chen, Oluwaseun A. Dada, Zhihao Ding, Margaret G. Ehm, Kari Eklund, Martti Färkkilä, Hilary Finucane, Andrea Ganna, Awaisa Ghazal, Robert R. Graham, Eric M. Green, Antti Hakanen, Marco Hautalahti, Åsa K. Hedman, Mikko Hiltunen, Reetta Hinttala, Iiris Hovatta, Xinli Hu, Adriana Huertas-Vazquez, Laura Huilaja, Julie Hunkapiller, Howard Jacob, Jan-Nygaard Jensen, Heikki Joensuu, Sally John, Valtteri Julkunen, Marc Jung, Juhani Junttila, Kai Kaarniranta, Mika Kähönen, Risto Kajanne, Lila Kallio, Reetta Kälviäinen, Jaakko Kaprio, Nurlan Kerimov, Johannes Kettunen, Elina Kilpeläinen, Terhi Kilpi, Katherine Klinger, Veli-Matti Kosma, Teijo Kuopio, Venla Kurra, Triin Laisk, Jari Laukkanen, Nathan Lawless, Aoxing Liu, Simonne Longerich, Reedik Mägi, Johanna Mäkelä, Antti Mäkitie, Anders Malarstig, Arto Mannermaa, Joseph Maranville, Athena Matakidou, Tuomo Meretoja, Sahar V. Mozaffari, Mari E. K. Niemi, Marianna Niemi, Teemu Niiranen, Christopher J. O´Donnell, Ma´en Obeidat, George Okafo, Hanna M. Ollila, Antti Palomäki, Tuula Palotie, Jukka Partanen, Dirk S. Paul, Margit Pelkonen, Rion K. Pendergrass, Slavé Petrovski, Anne Pitkäranta, Adam Platt, David Pulford, Eero Punkka, Pirkko Pussinen, Neha Raghavan, Fedik Rahimov, Deepak Rajpal, Nicole A. Renaud, Bridget Riley-Gillis, Rodosthenis Rodosthenous, Elmo Saarentaus, Aino Salminen, Eveliina Salminen, Veikko Salomaa, Johanna Schleutker, Raisa Serpi, Huei-Yi Shen, Richard Siegel, Kaisa Silander, Sanna Siltanen, Sirpa Soini, Hilkka Soininen, Jae Hoon Sul, Ioanna Tachmazidou, Kaisa Tasanen, Pentti Tienari, Sanna Toppila-Salmi, Taru Tukiainen, Tiinamaija Tuomi, Joni A. Turunen, Jacob C. Ulirsch, Felix Vaura, Petri Virolainen, Jeffrey Waring, Dawn Waterworth, Robert Yang, Mari Nelis, Anu Reigo, Andres Metspalu, Lili Milani, Tõnu Esko, Caroline Fox, Aki S. Havulinna, Markus Perola, Samuli Ripatti, Anu Jalanko, Tarja Laitinen, Tomi P. Mäkelä, Robert Plenge, Mark McCarthy, Heiko Runz, Mark J. Daly, Aarno Palotie
Feb 09, 2023
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived...
FinnGen provides genetic insights from a well-phenotyped isolated population.
Mitja I Kurki, Juha Karjalainen, Priit Palta, Timo P Sipilä, Kati Kristiansson, Kati M Donner, Mary P Reeve, Hannele Laivuori, Mervi Aavikko, Mari A Kaunisto, Anu Loukola, Elisa Lahtela, Hannele Mattsson, Päivi Laiho, Pietro Della Briotta Parolo, Arto A Lehisto, Masahiro Kanai, Nina Mars, Joel Rämö, Tuomo Kiiskinen, Henrike O Heyne, Kumar Veerapen, Sina Rüeger, Susanna Lemmelä, Wei Zhou, Sanni Ruotsalainen, Kalle Pärn, Tero Hiekkalinna, Sami Koskelainen, Teemu Paajanen, Vincent Llorens, Javier Gracia-Tabuenca, Harri Siirtola, Kadri Reis, Abdelrahman G Elnahas, Benjamin Sun, Christopher N Foley, Katriina Aalto-Setälä, Kaur Alasoo, Mikko Arvas, Kirsi Auro, Shameek Biswas, Argyro Bizaki-Vallaskangas, Olli Carpen, Chia-Yen Chen, Oluwaseun A Dada, Zhihao Ding, Margaret G Ehm, Kari Eklund, Martti Färkkilä, Hilary Finucane, Andrea Ganna, Awaisa Ghazal, Robert R Graham, Eric M Green, Antti Hakanen, Marco Hautalahti, Åsa K Hedman, Mikko Hiltunen, Reetta Hinttala, Iiris Hovatta, Xinli Hu, Adriana Huertas-Vazquez, Laura Huilaja, Julie Hunkapiller, Howard Jacob, Jan-Nygaard Jensen, Heikki Joensuu, Sally John, Valtteri Julkunen, Marc Jung, Juhani Junttila, Kai Kaarniranta, Mika Kähönen, Risto Kajanne, Lila Kallio, Reetta Kälviäinen, Jaakko Kaprio, FinnGen, Nurlan Kerimov, Johannes Kettunen, Elina Kilpeläinen, Terhi Kilpi, Katherine Klinger, Veli-Matti Kosma, Teijo Kuopio, Venla Kurra, Triin Laisk, Jari Laukkanen, Nathan Lawless, Aoxing Liu, Simonne Longerich, Reedik Mägi, Johanna Mäkelä, Antti Mäkitie, Anders Malarstig, Arto Mannermaa, Joseph Maranville, Athena Matakidou, Tuomo Meretoja, Sahar V Mozaffari, Mari EK Niemi, Marianna Niemi, Teemu Niiranen, Christopher J O Donnell, Ma En Obeidat, George Okafo, Hanna M Ollila, Antti Palomäki, Tuula Palotie, Jukka Partanen, Dirk S Paul, Margit Pelkonen, Rion K Pendergrass, Slavé Petrovski, Anne Pitkäranta, Adam Platt, David Pulford, Eero Punkka, Pirkko Pussinen, Neha Raghavan, Fedik Rahimov, Deepak Rajpal, Nicole A Renaud, Bridget Riley-Gillis, Rodosthenis Rodosthenous, Elmo Saarentaus, Aino Salminen, Eveliina Salminen, Veikko Salomaa, Johanna Schleutker, Raisa Serpi, Huei-Yi Shen, Richard Siegel, Kaisa Silander, Sanna Siltanen, Sirpa Soini, Hilkka Soininen, Jae Hoon Sul, Ioanna Tachmazidou, Kaisa Tasanen, Pentti Tienari, Sanna Toppila-Salmi, Taru Tukiainen, Tiinamaija Tuomi, Joni A Turunen, Jacob C Ulirsch, Felix Vaura, Petri Virolainen, Jeffrey Waring, Dawn Waterworth, Robert Yang, Mari Nelis, Anu Reigo, Andres Metspalu, Lili Milani, Tõnu Esko, Caroline Fox, Aki S Havulinna, Markus Perola, Samuli Ripatti, Anu Jalanko, Tarja Laitinen, Tomi P Mäkelä, Robert Plenge, Mark McCarthy, Heiko Runz, Mark J Daly, Aarno Palotie
Jan 19, 2023
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived...
|
|< |
< |
1 |