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Colombia's Fork in the Road? President Santos' Treaty with The Revolutionary Armed Forces of Colombia (FARC)
Ella Adriana Chirinos
Aug 22, 2017
Colombia is considered Latin America’s most stable democracy; meanwhile, it is war-torn by the internal conflict with the guerrilla group, the Revolutionary Armed Forces of Colombia (FARC). The armed conflict with the FARC has...
Published by: Memorial University of Newfoundland
Colombia's Fork in the Road? President Santos' Treaty with The Revolutionary Armed Forces of Colombia (FARC)
Ella Adriana Chirinos
Aug 22, 2017
Colombia is considered Latin America’s most stable democracy; meanwhile, it is war-torn by the internal conflict with the guerrilla group, the Revolutionary Armed Forces of Colombia (FARC). The armed conflict with the FARC has...
Published by: Memorial University of Newfoundland
A System Dynamics Model for Sales and Operations Planning
The use of system dynamics techniques to model the sales and operations planning (S&OP), associated with the economic and financial processes, is an innovative proposal. The objectives of this article are to model and simulate...
Published by: IGI Global Scientific Publishing
Blowups with log canonical singularities
We show that the minimum weight of a weighted blowup of Ad with ε–log canonical singularities is bounded by a constant depending only on ε and d . This was conjectured by Birkar. Using the recent classification of...
Blowups with log canonical singularities
We show that the minimum weight of a weighted blowup of Ad with ε–log canonical singularities is bounded by a constant depending only on ε and d . This was conjectured by Birkar. Using the recent classification of...
ISG15-Induced IL-10 Is a Novel Anti-Inflammatory Myeloid Axis Disrupted during Active Tuberculosis.
Mind the Gap
The way organelles are viewed by cell biologists is quickly changing. For many years, these cellular entities were thought to be unique and singular structures that performed specific roles. However, in recent decades...
Ancestral chromosomal signatures of Paenungulata (Afroteria) reveal the karyotype of Amazonian manatee (Trichechus inunguis, Sirenia
Flávia Dos Santos Tavares, Willam Oliveira da Silva, Malcolm Andrew Ferguson-Smith, Alex Garcia Cavalleiro de Macedo Klautau, Jairo Moura Oliveira, Angélica Lúcia Figueiredo Rodrigues, Gabriel Melo-Santos, Julio Cesar Pieczarka, Cleusa Yoshiko Nagamachi, Renata Coelho Rodrigues Noronha
Jan 24, 2023
BACKGROUND: Chromosomal painting in manatees has clarified questions about the rapid evolution of sirenians within the Paenungulata clade. Further cytogenetic studies in Afrotherian species may provide information about their...
Paracetamol Is Associated with a Lower Risk of COVID-19 Infection and Decreased ACE2 Protein Expression
Ibuprofen is a common over-the-counter drug taken for pain relief. However, recent studies have raised concerns about its potential toxic effect with coronavirus disease 2019 (COVID-19), which is caused by severe acute...
Alzheimer's and Parkinson's Diseases Predict Different COVID-19 Outcomes
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID-19). This was first described in the Wuhan province of...
Alzheimer’s and Parkinson’s Diseases Predict Different COVID-19 Outcomes
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID-19). This was first described in the Wuhan province of...
Superoxide Dismutase-3 Downregulates Laminin α5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling.
Lorena Carmona-Rodríguez, Diego Martínez-Rey, Paula Martín-González, Mónica Franch, Lydia Sorokin, Emilia Mira, Santos Mañes
Mar 02, 2022
The balance between laminin isoforms containing the α5 or the α4 chain in the endothelial basement membrane determines the site of leukocyte diapedesis under inflammatory conditions. Extracellular superoxide dismutase (SOD3)...
Links between air pollution and COVID-19 in England.
Marco Travaglio, Yizhou Yu, Rebeka Popovic, Liza Selley, Nuno Santos Leal, Luis Miguel Martins
Feb 26, 2021
In December 2019, a novel disease, coronavirus disease 19 (COVID-19), emerged in Wuhan, People's Republic of China. COVID-19 is caused by a novel coronavirus (SARS-CoV-2) presumed to have jumped species from another mammal to...
Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson's disease.
Rebeka Popovic, Amrita Mukherjee, Nuno Santos Leal, Lydia Morris, Yizhou Yu, Samantha H Y Loh, L Miguel Martins
Apr 17, 2023
Parkinson's disease (PD) is characterised by selective death of dopaminergic (DA) neurons in the midbrain and motor function impairment. Gastrointestinal issues often precede motor deficits in PD, indicating that the gut-brain...
Animals Drosophila Drosophila melanogaster Parkinson Disease Drosophila Proteins Unfolded Protein Response Protein Serine-Threonine Kinases
Published by: Cell Death & Disease
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.
María M Caffarel, Clara Andradas, Emilia Mira, Eduardo Pérez-Gómez, Camilla Cerutti, Gema Moreno-Bueno, Juana M Flores, Isabel García-Real, José Palacios, Santos Mañes, Manuel Guzmán, Cristina Sánchez
Jun 16, 2011
To go or not to go with the flow
Jorge E. Santos
Sep 24, 2020
Abstract: We construct the gravitational dual of a one-parameter class of states of strongly coupled SU(N) N = 4 SYM at infinite N and asymptotic temperature T∞, on a fixed Schwarzschild black hole background with temperature...
Identification of Modifier Genes in a Mouse Model of Gaucher Disease.
Andrés D Klein, Natalia-Santos Ferreira, Shifra Ben-Dor, Jingjing Duan, John Hardy, Timothy M Cox, Alfred H Merrill, Anthony H Futerman
Oct 24, 2016
Effects of dietary intake patterns from 1 to 4 years on BMI z-score and body shape at age of 6 years
PURPOSE: To assess the association between dietary intake patterns from 1 to 4 years and BMI and body shape at age of 6 years. METHODS: This longitudinal study was based on 3374 Brazilian children from the 2004 Pelotas Birth...
Amyloid Β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer's Disease-Related Models.
Nuno Santos Leal, Giacomo Dentoni, Bernadette Schreiner, Luana Naia, Antonio Piras, Caroline Graff, Antonio Cattaneo, Giovanni Meli, Maho Hamasaki, Per Nilsson, Maria Ankarcrona
Nov 29, 2020
Recent findings have shown that the connectivity and crosstalk between mitochondria and the endoplasmic reticulum (ER) at mitochondria-ER contact sites (MERCS) are altered in Alzheimer's disease (AD) and in AD-related models....
Alzheimer’s disease Mitochondria-ER contact sites amyloid β-peptide Autophagy Mitochondria Aged Aged 80 and over Alzheimer Disease Amyloid beta-Peptides Animals Autophagosomes Brain Disease Models Animal Endoplasmic Reticulum Female Homeostasis Humans Male Mice Mice Transgenic Middle Aged Mitochondria Mitochondrial Membrane Transport Proteins Mitochondrial Membranes Neurons Up-Regulation
Fitness but not weight status is associated with projected physical independence in older adults.
Physical Education Classes, Physical Activity, and Sedentary Behavior in Children
Diego Augusto Santos Silva, Jean-Philippe Chaput, Peter T Katzmarzyk, Mikael Fogelholm, Gang Hu, Carol Maher, Timothy Olds, Vincent Onywera, Olga L Sarmiento, Martyn Standage, Catrine Tudor-Locke, Mark S Tremblay
May 01, 2018
Purpose This study aimed to examine the associations between participation frequency in physical education (PE) classes and objective measures of physical activity (PA) and sedentary behavior (SB) in children from 12...
DNA-PKcs restricts Zika virus spreading and is required for effective antiviral response.
Daniel de Oliveira Patricio, Greicy Brisa Malaquias Dias, Lucilene Wildner Granella, Ben Trigg, Helena Claire Teague, Dina Bittencourt, André Báfica, Alfeu Zanotto-Filho, Brian Ferguson, Daniel Santos Mansur
Oct 27, 2022
Co-translational assembly orchestrates competing biogenesis pathways.
Maximilian Seidel, Anja Becker, Filipa Pereira, Jonathan JM Landry, Nayara Trevisan Doimo de Azevedo, Claudia M Fusco, Eva Kaindl, Natalie Romanov, Janina Baumbach, Julian D Langer, Erin M Schuman, Kiran Raosaheb Patil, Gerhard Hummer, Vladimir Benes, Martin Beck
Mar 09, 2022
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