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Results: 23
Current Status of the Food Industry in Indonesia
Hendra Wijaya, Zaekhan Zaekhan, Lukman Junaidi, Ning Wardayanie, Yuliasri Meutia, Nona Widharosa, Tita Rosita
Feb 24, 2023
This study assesses the contribution of the food and beverage industry to the Indonesian economy based on firm characteristics. The comparative descriptive statistical method describes a detailed mapping of the firm's character...
Published by: IGI Global Scientific Publishing
Efficient Red Organic Light Emitting Diodes of Nona Coordinate Europium Tris(β-diketonato) Complexes Bearing 4'-Phenyl-2,2'
Rashid Ilmi, Jingyu Wang, José D.L. Dutra, Liang Zhou, Wei-Yeung Wong, Paul R. Raithby, Muhammad Khan
Jul 03, 2023
Two novel nona-coordinated Eu(III) complexes [Eu(btfa) 3(Ph-TerPyr)] (Eu-1) and [Eu(NTA) 3(Ph-TerPyr)] (Eu-2) have been synthesized and characterized. The structure of the complexes was elucidated by...
Efficient Red Organic Light Emitting Diodes of Nona Coordinate Europium Tris(β-diketonato) Complexes Bearing 4'-Phenyl-2,2'
Rashid Ilmi, Jingyu Wang, José D.L. Dutra, Liang Zhou, Wei-Yeung Wong, Paul R. Raithby, Muhammad Khan
Jul 03, 2023
Two novel nona-coordinated Eu(III) complexes [Eu(btfa) 3(Ph-TerPyr)] (Eu-1) and [Eu(NTA) 3(Ph-TerPyr)] (Eu-2) have been synthesized and characterized. The structure of the complexes was elucidated by...
Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant.
Motaharehsadat Heydarian, Prajakta Oak, Xin Zhang, Nona Kamgari, Alida Kindt, Markus Koschlig, Tina Pritzke, Erika Gonzalez-Rodriguez, Kai Förster, Rory E Morty, Friederike Häfner, Christoph Hübener, Andreas W Flemmer, Ali Oender Yildirim, Deepti Sudheendra, Xuefei Tian, Agnese Petrera, Holger Kirsten, Peter Ahnert, Nick Morrell, Tushar J Desai, Jennifer Sucre, Edda Spiekerkoetter, Anne Hilgendorff
Nov 03, 2022
Meta-analysis of epigenome-wide association studies of carotid intima-media thickness.
Eliana Portilla-Fernández, Shih-Jen Hwang, Rory Wilson, Jane Maddock, W David Hill, Alexander Teumer, Pashupati P Mishra, Jennifer A Brody, Roby Joehanes, Symen Ligthart, Mohsen Ghanbari, Maryam Kavousi, Anton JM Roks, AH Jan Danser, Daniel Levy, Annette Peters, Sahar Ghasemi, Ulf Schminke, Marcus Dörr, Hans J Grabe, Terho Lehtimäki, Mika Kähönen, Mikko A Hurme, Traci M Bartz, Nona Sotoodehnia, Joshua C Bis, Joachim Thiery, Wolfgang Koenig, Kenneth Ong, Jordana T Bell, Christine Meisinger, Joanna M Wardlaw, John M Starr, Jochen Seissler, Cornelia Then, Wolfgang Rathmann, M Arfan Ikram, Bruce M Psaty, Olli T Raitakari, Henry Völzke, Ian J Deary, Andrew Wong, Melanie Waldenberger, Christopher J O'Donnell, Abbas Dehghan
Jun 14, 2021
Common carotid intima-media thickness (cIMT) is an index of subclinical atherosclerosis that is associated with ischemic stroke and coronary artery disease (CAD). We undertook a cross-sectional epigenome-wide association study...
Testing the role of predicted gene knockouts in human anthropometric trait variation.
Samuel Lessard, Alisa K Manning, Cécile Low-Kam, Paul L Auer, Ayush Giri, Mariaelisa Graff, Claudia Schurmann, Hanieh Yaghootkar, Jian'an Luan, Tonu Esko, Tugce Karaderi, NHLBI GO Exome Sequence Project, GOT2D, T2D-GENES, GIANT Consortium, Erwin P Bottinger, Yingchang Lu, Chris Carlson, Mark Caulfield, Marie-Pierre Dubé, Rebecca D Jackson, Charles Kooperberg, Barbara McKnight, Ian Mongrain, Ulrike Peters, Alex P Reiner, David Rhainds, Nona Sotoodehnia, Joel N Hirschhorn, Robert A Scott, Patricia B Munroe, Timothy M Frayling, Ruth JF Loos, Kari E North, Todd L Edwards, Jean-Claude Tardif, Cecilia M Lindgren, Guillaume Lettre
Mar 14, 2016
Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes
Amanda M Fretts, Fumiaki Imamura, Matti Marklund, Renata Micha, Jason HY Wu, Rachel A Murphy, Kuo-Liong Chien, Barbara McKnight, Nathan Tintle, Nita G Forouhi, Waqas T Qureshi, Jyrki K Virtanen, Kerry Wong, Alexis C Wood, Maria Lankinen, Kalina Rajaobelina, Tamara B Harris, Luc Djoussé, Bill Harris, Nick J Wareham, Lyn M Steffen, Markku Laakso, Jenna Veenstra, Cécilia Samieri, Ingeborg A Brouwer, Chaoyu Ian Yu, Albert Koulman, Brian T Steffen, Catherine Helmer, Nona Sotoodehnia, David Siscovick, Vilmundur Gudnason, InterAct Consortium, Lynne Wagenknecht, Sari Voutilainen, Michael Y Tsai, Matti Uusitupa, Anya Kalsbeek, Claudine Berr, Dariush Mozaffarian, Rozenn N Lemaitre
Feb 01, 2019
Cohorts for Heart and Aging Research in Genomic Epidemiology Fatty Acids and Outcomes Research Consortium Diabetes Meta-Analysis saturated fatty acids very-long-chain saturated fatty acids Adult Aged Aged 80 and over Diabetes mellitus Type 2 Eicosanoic Acids Fatty Acids Female Humans Male Middle Aged Prospective Studies
Meta-analysis of epigenome-wide association studies of carotid intima-media thickness.
Eliana Portilla-Fernández, Shih-Jen Hwang, Rory Wilson, Jane Maddock, W David Hill, Alexander Teumer, Pashupati P Mishra, Jennifer A Brody, Roby Joehanes, Symen Ligthart, Mohsen Ghanbari, Maryam Kavousi, Anton JM Roks, AH Jan Danser, Daniel Levy, Annette Peters, Sahar Ghasemi, Ulf Schminke, Marcus Dörr, Hans J Grabe, Terho Lehtimäki, Mika Kähönen, Mikko A Hurme, Traci M Bartz, Nona Sotoodehnia, Joshua C Bis, Joachim Thiery, Wolfgang Koenig, Ken K Ong, Jordana T Bell, Christine Meisinger, Joanna M Wardlaw, John M Starr, Jochen Seissler, Cornelia Then, Wolfgang Rathmann, M Arfan Ikram, Bruce M Psaty, Olli T Raitakari, Henry Völzke, Ian J Deary, Andrew Wong, Melanie Waldenberger, Christopher J O'Donnell, Abbas Dehghan
Dec 15, 2021
cardiovascular risk factors Common carotid intima-media thickness DNA Methylation Differentially methylated regions Epigenome-wide association studies Mendelian randomization Vascular outcomes Carotid Intima-Media Thickness Coronary Artery Disease Cross-Sectional Studies epigenome Humans Risk Factors
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes
Fumiaki Imamura, Amanda Fretts, Matti Marklund, Andres V Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Kerry Wong, Julie K Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A Brouwer, Kuo-Liong Chien, Alexis C Frazier-Wood, Liana C Del Gobbo, Luc Djoussé, Johanna M Geleijnse, Graham G Giles, Janette de Goede, Vilmundur Gudnason, William S Harris, Allison Hodge, Frank Hu, InterAct Consortium, Albert Koulman, Markku Laakso, Lars Lind, Hung-Ju Lin, Barbara McKnight, Kalina Rajaobelina, Ulf Risérus, Jennifer G Robinson, Cécilia Samieri, David S Siscovick, Sabita S Soedamah-Muthu, Nona Sotoodehnia, Qi Sun, Michael Y Tsai, Matti Uusitupa, Lynne E Wagenknecht, Nick J Wareham, Jason HY Wu, Renata Micha, Nita G Forouhi, Rozenn N Lemaitre, Dariush Mozaffarian, Fatty Acids and Outcomes Research Consortium (FORCE)
Nov 16, 2018
BACKGROUND: We aimed to investigate prospective associations of circulating or adipose tissue odd-chain fatty acids 15:0 and 17:0 and trans-palmitoleic acid, t16:1n-7, as potential biomarkers of dairy fat intake, with incident...
Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes
Fumiaki Imamura, Amanda M. Fretts, Matti Marklund, Andres V. Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Jyrki K. Virtanen, Kerry Wong, Julie K. Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A. Brouwer, Kuo-Liong Chien, Yun-Yu Chen, Alexis C. Wood, Liana C. del Gobbo, Luc Djousse, Johanna M. Geleijnse, Graham G. Giles, Janette de Goede, Vilmundur Gudnason, William S. Harris, Allison Hodge, Frank Hu, InterAct Consortium, Albert Koulman, Markku Laakso, Lars Lind, Hung-Ju Lin, Barbara McKnight, Kalina Rajaobelina, Ulf Riserus, Jennifer G. Robinson, Cecilia Samieri, Mackenzie Senn, David S. Siscovick, Sabita S. Soedamah-Muthu, Nona Sotoodehnia, Qi Sun, Michael Y. Tsai, Tomi-Pekka Tuomainen, Matti Uusitupa, Lynne E. Wagenknecht, Nick J. Wareham, Jason H. Y. Wu, Renata Micha, Rozenn N. Lemaitre, Dariush Mozaffarian, Nita G. Forouhi
Jun 12, 2020
Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes
Fumiaki Imamura, Amanda M Fretts, Matti Marklund, Andres V Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Jyrki K Virtanen, Kerry Wong, Julie K Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A Brouwer, Kuo-Liong Chien, Yun-Yu Chen, Alexis C Wood, Liana C Del Gobbo, Luc Djousse, Johanna M Geleijnse, Graham G Giles, Janette de Goede, Vilmundur Gudnason, William S Harris, Allison Hodge, Frank Hu, InterAct Consortium, Albert Koulman, Markku Laakso, Lars Lind, Hung-Ju Lin, Barbara McKnight, Kalina Rajaobelina, Ulf Riserus, Jennifer G Robinson, Cecilia Samieri, Mackenzie Senn, David S Siscovick, Sabita S Soedamah-Muthu, Nona Sotoodehnia, Qi Sun, Michael Y Tsai, Tomi-Pekka Tuomainen, Matti Uusitupa, Lynne E Wagenknecht, Nick J Wareham, Jason HY Wu, Renata Micha, Rozenn N Lemaitre, Dariush Mozaffarian, Nita G Forouhi
May 01, 2020
Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.
Sinjini Sikdar, Roby Joehanes, Bonnie R Joubert, Cheng-Jian Xu, Marta Vives-Usano, Faisal I Rezwan, Janine F Felix, James M Ward, Weihua Guan, Rebecca C Richmond, Jennifer A Brody, Leanne K Küpers, Nour Baïz, Siri E Håberg, Jennifer A Smith, Sarah E Reese, Stella Aslibekyan, Cathrine Hoyo, Radhika Dhingra, Christina A Markunas, Tao Xu, Lindsay M Reynolds, Allan C Just, Pooja R Mandaviya, Akram Ghantous, Brian D Bennett, Tianyuan Wang, The Bios Consortium, Kelly M Bakulski, Erik Melen, Shanshan Zhao, Jianping Jin, Zdenko Herceg, Joyce van Meurs, Jack A Taylor, Andrea A Baccarelli, Susan K Murphy, Yongmei Liu, Monica Cheng Munthe-Kaas, Ian J Deary, Wenche Nystad, Melanie Waldenberger, Isabella Annesi-Maesano, Karen Conneely, Vincent WV Jaddoe, Donna Arnett, Harold Snieder, Sharon LR Kardia, Caroline L Relton, Ken K Ong, Susan Ewart, Hortensia Moreno-Macias, Isabelle Romieu, Nona Sotoodehnia, Myriam Fornage, Alison Motsinger-Reif, Gerard H Koppelman, Mariona Bustamante, Daniel Levy, Stephanie J London
Oct 08, 2019
Aim: Cigarette smoking influences DNA methylation genome wide, in newborns from pregnancy exposure and in adults from personal smoking. Whether a unique methylation signature exists for in utero exposure in newborns is unknown....
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.
Matthias Wielscher, Pooja R Mandaviya, Brigitte Kuehnel, Roby Joehanes, Rima Mustafa, Oliver Robinson, Yan Zhang, Barbara Bodinier, Esther Walton, Pashupati P Mishra, Pascal Schlosser, Rory Wilson, Pei-Chien Tsai, Saranya Palaniswamy, Riccardo E Marioni, Giovanni Fiorito, Giovanni Cugliari, Ville Karhunen, Mohsen Ghanbari, Bruce M Psaty, Marie Loh, Joshua C Bis, Benjamin Lehne, Nona Sotoodehnia, Ian J Deary, Marc Chadeau-Hyam, Jennifer A Brody, Alexia Cardona, Elizabeth Selvin, Alicia K Smith, Andrew H Miller, Mylin A Torres, Eirini Marouli, Xin Gào, Joyce BJ van Meurs, Johanna Graf-Schindler, Wolfgang Rathmann, Wolfgang Koenig, Annette Peters, Wolfgang Weninger, Matthias Farlik, Tao ZHANG, Wei Chen, Yujing Xia, Alexander Teumer, Matthias Nauck, Hans J Grabe, Macus Doerr, Terho Lehtimäki, Weihua Guan, Lili Milani, Toshiko Tanaka, Krista Fisher, Lindsay L Waite, Silva Kasela, Paolo Vineis, Niek Verweij, Pim van der Harst, Licia Iacoviello, Carlotta Sacerdote, Salvatore Panico, Vittorio Krogh, Rosario Tumino, Evangelia Tzala, Giuseppe Matullo, Mikko A Hurme, Olli T Raitakari, Elena Colicino, Andrea A Baccarelli, Mika Kähönen, Karl-Heinz Herzig, Shengxu Li, BIOS Consortium, Karen N Conneely, Jaspal S Kooner, Anna Köttgen, Bastiaan T Heijmans, Panos Deloukas, Caroline Relton, Kenneth Ong, Jordana T Bell, Eric Boerwinkle, Paul Elliott, Hermann Brenner, Marian Beekman, Daniel Levy, Melanie Waldenberger, John C Chambers, Abbas Dehghan, Marjo-Riitta Järvelin
May 09, 2022
We performed a multi-ethnic Epigenome Wide Association study on 22,774 individuals to describe the DNA methylation signature of chronic low-grade inflammation as measured by C-Reactive protein (CRP). We find 1,511 independent...
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
Bram P Prins, Timothy J Mead, Jennifer A Brody, Gardar Sveinbjornsson, Ioanna Ntalla, Nathan A Bihlmeyer, Marten van den Berg, Jette Bork-Jensen, Stefania Cappellani, Stefan Van Duijvenboden, Nikolai T Klena, George C Gabriel, Xiaoqin Liu, Cagri Gulec, Niels Grarup, Jeffrey Haessler, Leanne M Hall, Annamaria Iorio, Aaron Isaacs, Ruifang Li-Gao, Honghuang Lin, Ching-Ti Liu, Leo-Pekka Lyytikäinen, Jonathan Marten, Hao Mei, Martina Müller-Nurasyid, Michele Orini, Sandosh Padmanabhan, Farid Radmanesh, Julia Ramirez, Antonietta Robino, Molly Schwartz, Jessica van Setten, Albert V Smith, Niek Verweij, Helen R Warren, Stefan Weiss, Alvaro Alonso, David O Arnar, Michiel L Bots, Rudolf A de Boer, Anna F Dominiczak, Mark Eijgelsheim, Patrick T Ellinor, Xiuqing Guo, Stephan B Felix, Tamara B Harris, Caroline Hayward, Susan R Heckbert, Paul L Huang, JW Jukema, Mika Kähönen, Jan A Kors, Pier D Lambiase, Lenore J Launer, Man Li, Allan Linneberg, Christopher P Nelson, Oluf Pedersen, Marco Perez, Annette Peters, Ozren Polasek, Bruce M Psaty, Olli T Raitakari, Kenneth M Rice, Jerome I Rotter, Moritz F Sinner, Elsayed Z Soliman, Tim D Spector, Konstantin Strauch, Unnur Thorsteinsdottir, Andrew Tinker, Stella Trompet, André Uitterlinden, Ilonca Vaartjes, Peter van der Meer, Uwe Völker, Henry Völzke, Melanie Waldenberger, James G Wilson, Zhijun Xie, Folkert W Asselbergs, Marcus Dörr, Cornelia M van Duijn, Paolo Gasparini, Daniel F Gudbjartsson, Vilmundur Gudnason, Torben Hansen, Stefan Kääb, Jørgen K Kanters, Charles Kooperberg, Terho Lehtimäki, Henry J Lin, Steven A Lubitz, Dennis O Mook-Kanamori, Francesco J Conti, Christopher H Newton-Cheh, Jonathan Rosand, Igor Rudan, Nilesh J Samani, Gianfranco Sinagra, Blair H Smith, Hilma Holm, Bruno H Stricker, Sheila Ulivi, Nona Sotoodehnia, Suneel S Apte, Pim van der Harst, Kari Stefansson, Patricia B Munroe, Dan E Arking, Cecilia W Lo, Yalda Jamshidi
Sep 17, 2018
ADAMTS6 Conduction exome chip Meta-Analysis ADAMTS Proteins Animals Black People Connexin 43 Electrocardiography Exome Female Gene Expression Gene Expression Profiling Genetic Loci Genome-Wide Association Study Heart Conduction System Humans Male Mice Middle Aged Myocardium Open Reading Frames Polymorphism Single Nucleotide White People Exome Sequencing
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Symen Ligthart, Carola Marzi, Stella Aslibekyan, Michael M Mendelson, Karen N Conneely, Toshiko Tanaka, Elena Colicino, Lindsay L Waite, Roby Joehanes, Weihua Guan, Jennifer A Brody, Cathy Elks, Riccardo Marioni, Min A Jhun, Golareh Agha, Jan Bressler, Cavin K Ward-Caviness, Brian H Chen, Tianxiao Huan, Kelly Bakulski, Elias L Salfati, WHI-EMPC Investigators, Giovanni Fiorito, CHARGE epigenetics of Coronary Heart Disease, Simone Wahl, Katharina Schramm, Jin Sha, Dena G Hernandez, Allan C Just, Jennifer A Smith, Nona Sotoodehnia, Luke C Pilling, James S Pankow, Phil S Tsao, Chunyu Liu, Wei Zhao, Simonetta Guarrera, Vasiliki J Michopoulos, Alicia K Smith, Marjolein J Peters, David Melzer, Pantel Vokonas, Myriam Fornage, Holger Prokisch, Joshua C Bis, Audrey Y Chu, Christian Herder, Harald Grallert, Chen Yao, Sonia Shah, Allan F McRae, Honghuang Lin, Steve Horvath, Daniele Fallin, Albert Hofman, Nicholas J Wareham, Kerri L Wiggins, Andrew P Feinberg, John M Starr, Peter M Visscher, Joanne M Murabito, Sharon LR Kardia, Devin M Absher, Elisabeth B Binder, Andrew B Singleton, Stefania Bandinelli, Annette Peters, Melanie Waldenberger, Giuseppe Matullo, Joel D Schwartz, Ellen W Demerath, André G Uitterlinden, Joyce BJ van Meurs, Oscar H Franco, Yii-Der Ida Chen, Daniel Levy, Stephen T Turner, Ian J Deary, Kerry J Ressler, Josée Dupuis, Luigi Ferrucci, Ken K Ong, Themistocles L Assimes, Eric Boerwinkle, Wolfgang Koenig, Donna K Arnett, Andrea A Baccarelli, Emelia J Benjamin, Abbas Dehghan
Feb 06, 2017
BACKGROUND: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA methylation is associated with chronic low-grade...
Body Mass Index C-Reactive Protein coronary heart disease DNA Methylation Diabetes Epigenome-wide association study Inflammation Black or African American C-Reactive Protein CpG Islands DNA Methylation Epigenesis Genetic Female Gene Expression genetic variation Genome-Wide Association Study Humans Inflammation Male Nucleotide Motifs Quantitative Trait Loci White People
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.
Matthias Wielscher, Pooja R Mandaviya, Brigitte Kuehnel, Roby Joehanes, Rima Mustafa, Oliver Robinson, Yan Zhang, Barbara Bodinier, Esther Walton, Pashupati P Mishra, Pascal Schlosser, Rory Wilson, Pei-Chien Tsai, Saranya Palaniswamy, Riccardo E Marioni, Giovanni Fiorito, Giovanni Cugliari, Ville Karhunen, Mohsen Ghanbari, Bruce M Psaty, Marie Loh, Joshua C Bis, Benjamin Lehne, Nona Sotoodehnia, Ian J Deary, Marc Chadeau-Hyam, Jennifer A Brody, Alexia Cardona, Elizabeth Selvin, Alicia K Smith, Andrew H Miller, Mylin A Torres, Eirini Marouli, Xin Gào, Joyce BJ van Meurs, Johanna Graf-Schindler, Wolfgang Rathmann, Wolfgang Koenig, Annette Peters, Wolfgang Weninger, Matthias Farlik, Tao ZHANG, Wei Chen, Yujing Xia, Alexander Teumer, Matthias Nauck, Hans J Grabe, Macus Doerr, Terho Lehtimäki, Weihua Guan, Lili Milani, Toshiko Tanaka, Krista Fisher, Lindsay L Waite, Silva Kasela, Paolo Vineis, Niek Verweij, Pim van der Harst, Licia Iacoviello, Carlotta Sacerdote, Salvatore Panico, Vittorio Krogh, Rosario Tumino, Evangelia Tzala, Giuseppe Matullo, Mikko A Hurme, Olli T Raitakari, Elena Colicino, Andrea A Baccarelli, Mika Kähönen, Karl-Heinz Herzig, Shengxu Li, BIOS Consortium, Karen N Conneely, Jaspal S Kooner, Anna Köttgen, Bastiaan T Heijmans, Panos Deloukas, Caroline Relton, Ken K Ong, Jordana T Bell, Eric Boerwinkle, Paul Elliott, Hermann Brenner, Marian Beekman, Daniel Levy, Melanie Waldenberger, John C Chambers, Abbas Dehghan, Marjo-Riitta Järvelin
Jun 07, 2022
We performed a multi-ethnic Epigenome Wide Association study on 22,774 individuals to describe the DNA methylation signature of chronic low-grade inflammation as measured by C-Reactive protein (CRP). We find 1,511 independent...
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
Philipp S Wild, Janine F Felix, Arne Schillert, Alexander Teumer, Ming-Huei Chen, Maarten JG Leening, Uwe Völker, Vera Großmann, Jennifer A Brody, Marguerite R Irvin, Sanjiv J Shah, Setia Pramana, Wolfgang Lieb, Reinhold Schmidt, Alice V Stanton, Dörthe Malzahn, Albert Vernon Smith, Johan Sundström, Cosetta Minelli, Daniela Ruggiero, Leo-Pekka Lyytikäinen, Daniel Tiller, J Gustav Smith, Claire Monnereau, Marco R Di Tullio, Solomon K Musani, Alanna C Morrison, Tune H Pers, Michael Morley, Marcus E Kleber, Jayashri Aragam, Emelia J Benjamin, Joshua C Bis, Egbert Bisping, Ulrich Broeckel, Susan Cheng, Jaap W Deckers, Fabiola del Greco M, Frank Edelmann, Myriam Fornage, Lude Franke, Nele Friedrich, Tamara B Harris, Edith Hofer, Albert Hofman, Jie Huang, Alun D Hughes, Mika Kähönen, Knhi Investigators, Jochen Kruppa, Karl J Lackner, Lars Lannfelt, Rafael Laskowski, Lenore J Launer, Margrét Leosdottir, Honghuang Lin, Cecilia M Lindgren, Christina Loley, Calum A MacRae, Deborah Mascalzoni, Jamil Mayet, Daniel Medenwald, Andrew P Morris, Christian Müller, Martina Müller-Nurasyid, Stefania Nappo, Peter M Nilsson, Sebastian Nuding, Teresa Nutile, Annette Peters, Arne Pfeufer, Diana Pietzner, Peter P Pramstaller, Olli T Raitakari, Kenneth M Rice, Fernando Rivadeneira, Jerome I Rotter, Saku T Ruohonen, Ralph L Sacco, Tandaw E Samdarshi, Helena Schmidt, Andrew SP Sharp, Denis C Shields, Rossella Sorice, Nona Sotoodehnia, Bruno H Stricker, Praveen Surendran, Simon Thom, Anna M Töglhofer, André G Uitterlinden, Rolf Wachter, Henry Völzke, Andreas Ziegler, Thomas Münzel, Winfried März, Thomas P Cappola, Joel N Hirschhorn, Gary F Mitchell, Nicholas L Smith, Ervin R Fox, Nicole D Dueker, Vincent WV Jaddoe, Olle Melander, Martin Russ, Terho Lehtimäki, Marina Ciullo, Andrew A Hicks, Lars Lind, Vilmundur Gudnason, Burkert Pieske, Anthony J Barron, Robert Zweiker, Heribert Schunkert, Erik Ingelsson, Kiang Liu, Donna K Arnett, Bruce M Psaty, Stefan Blankenberg, Martin G Larson, Stephan B Felix, Oscar H Franco, Tanja Zeller, Ramachandran S Vasan, Marcus Dörr
Nov 27, 2017
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Tuomas O Kilpeläinen, Amy R Bentley, Raymond Noordam, Yun Ju Sung, Karen Schwander, Thomas W Winkler, Hermina Jakupović, Daniel I Chasman, Alisa Manning, Ioanna Ntalla, Hugues Aschard, Michael R Brown, Lisa de Las Fuentes, Nora Franceschini, Xiuqing Guo, Dina Vojinovic, Stella Aslibekyan, Mary F Feitosa, Minjung Kho, Solomon K Musani, Melissa Richard, Heming Wang, Zhe Wang, Traci M Bartz, Lawrence F Bielak, Archie Campbell, Rajkumar Dorajoo, Virginia Fisher, Fernando P Hartwig, Andrea RVR Horimoto, Changwei Li, Kurt K Lohman, Jonathan Marten, Xueling Sim, Albert V Smith, Salman M Tajuddin, Maris Alver, Marzyeh Amini, Mathilde Boissel, Jin Fang Chai, Xu Chen, Jasmin Divers, Evangelos Evangelou, Chuan Gao, Mariaelisa Graff, Sarah E Harris, Meian He, Fang-Chi Hsu, Anne U Jackson, Jing Hua Zhao, Aldi T Kraja, Brigitte Kühnel, Federica Laguzzi, Leo-Pekka Lyytikäinen, Ilja M Nolte, Rainer Rauramaa, Muhammad Riaz, Antonietta Robino, Rico Rueedi, Heather M Stringham, Fumihiko Takeuchi, Peter J van der Most, Tibor V Varga, Niek Verweij, Erin B Ware, Wanqing Wen, Xiaoyin Li, Lisa R Yanek, Najaf Amin, Donna K Arnett, Eric Boerwinkle, Marco Brumat, Brian Cade, Mickaël Canouil, Yii-Der Ida Chen, Maria Pina Concas, John Connell, Renée de Mutsert, H Janaka de Silva, Paul S de Vries, Ayşe Demirkan, Jingzhong Ding, Charles B Eaton, Jessica D Faul, Yechiel Friedlander, Kelley P Gabriel, Mohsen Ghanbari, Franco Giulianini, Chi Charles Gu, Dongfeng Gu, Tamara B Harris, Jiang He, Sami Heikkinen, Chew-Kiat Heng, Steven C Hunt, M Arfan Ikram, Jost B Jonas, Woon-Puay Koh, Pirjo Komulainen, Jose E Krieger, Stephen B Kritchevsky, Zoltán Kutalik, Johanna Kuusisto, Carl D Langefeld, Claudia Langenberg, Lenore J Launer, Karin Leander, Rozenn N Lemaitre, Cora E Lewis, Jingjing Liang, Lifelines Cohort Study, Jianjun Liu, Reedik Mägi, Ani Manichaikul, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Karen L Mohlke, Thomas H Mosley, Alison D Murray, Mike A Nalls, Ei-Ei Khaing Nang, Christopher P Nelson, Sotoodehnia Nona, Jill M Norris, Chiamaka Vivian Nwuba, Jeff O'Connell, Nicholette D Palmer, George J Papanicolau, Raha Pazoki, Nancy L Pedersen, Annette Peters, Patricia A Peyser, Ozren Polasek, David J Porteous, Alaitz Poveda, Olli T Raitakari, Stephen S Rich, Neil Risch, Jennifer G Robinson, Lynda M Rose, Igor Rudan, Pamela J Schreiner, Robert A Scott, Stephen S Sidney, Mario Sims, Jennifer A Smith, Harold Snieder, Tamar Sofer, John M Starr, Barbara Sternfeld, Konstantin Strauch, Hua Tang, Kent D Taylor, Michael Y Tsai, Jaakko Tuomilehto, André G Uitterlinden, M Yldau van der Ende, Diana van Heemst, Trudy Voortman, Melanie Waldenberger, Patrik Wennberg, Gregory Wilson, Yong-Bing Xiang, Jie Yao, Caizheng Yu, Jian-Min Yuan, Wei Zhao, Alan B Zonderman, Diane M Becker, Michael Boehnke, Donald W Bowden, Ulf de Faire, Ian J Deary, Paul Elliott, Tõnu Esko, Barry I Freedman, Philippe Froguel, Paolo Gasparini, Christian Gieger, Norihiro Kato, Markku Laakso, Timo A Lakka, Terho Lehtimäki, Patrik KE Magnusson, Albertine J Oldehinkel, Brenda WJH Penninx, Nilesh J Samani, Xiao-Ou Shu, Pim van der Harst, Jana V van Vliet-Ostaptchouk, Peter Vollenweider, Lynne E Wagenknecht, Ya X Wang, Nicholas J Wareham, David R Weir, Tangchun Wu, Wei Zheng, Xiaofeng Zhu, Michele K Evans, Paul W Franks, Vilmundur Gudnason, Caroline Hayward, Bernardo L Horta, Tanika N Kelly, Yongmei Liu, Kari E North, Alexandre C Pereira, Paul M Ridker, E Shyong Tai, Rob M van Dam, Ervin R Fox, Sharon LR Kardia, Ching-Ti Liu, Dennis O Mook-Kanamori, Michael A Province, Susan Redline, Cornelia M van Duijn, Jerome I Rotter, Charles B Kooperberg, W James Gauderman, Bruce M Psaty, Kenneth Rice, Patricia B Munroe, Myriam Fornage, L Adrienne Cupples, Charles N Rotimi, Alanna C Morrison, Dabeeru C Rao, Ruth JF Loos
Feb 11, 2019
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we...
Adolescent Adult Aged Aged 80 and over Asian People Black People Brazil Calcium-Binding Proteins Cholesterol Cholesterol HDL Cholesterol LDL Exercise Female Genetic Loci Genome-Wide Association Study Genotype Hispanic or Latino Humans LIM-Homeodomain Proteins Lipid Metabolism Lipids Male Membrane Proteins Microtubule-Associated Proteins Middle Aged Muscle Proteins Nerve Tissue Proteins Transcription Factors Triglycerides White People Young Adult
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.
Ioanna Ntalla, Lu-Chen Weng, James H Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Nathan R Tucker, Seung Hoan Choi, Mark D Chaffin, Carolina Roselli, Michael R Barnes, Borbala Mifsud, Helen R Warren, Caroline Hayward, Jonathan Marten, James J Cranley, Maria Pina Concas, Paolo Gasparini, Thibaud Boutin, Ivana Kolcic, Ozren Polasek, Igor Rudan, Nathalia M Araujo, Maria Fernanda Lima-Costa, Antonio Luiz P Ribeiro, Renan P Souza, Eduardo Tarazona-Santos, Vilmantas Giedraitis, Erik Ingelsson, Anubha Mahajan, Andrew P Morris, Fabiola del Greco M, Luisa Foco, Martin Gögele, Andrew A Hicks, James P Cook, Lars Lind, Cecilia M Lindgren, Johan Sundström, Christopher P Nelson, Muhammad B Riaz, Nilesh J Samani, Gianfranco Sinagra, Sheila Ulivi, Mika Kähönen, Pashupati P Mishra, Nina Mononen, Kjell Nikus, Mark J Caulfield, Anna Dominiczak, Sandosh Padmanabhan, May E Montasser, Jeff R O'Connell, Kathleen Ryan, Alan R Shuldiner, Stefanie Aeschbacher, David Conen, Lorenz Risch, Sébastien Thériault, Nina Hutri-Kähönen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Olli T Raitakari, Catriona LK Barnes, Harry Campbell, Peter K Joshi, James F Wilson, Aaron Isaacs, Jan A Kors, Cornelia M van Duijn, Paul L Huang, Vilmundur Gudnason, Tamara B Harris, Lenore J Launer, Albert V Smith, Erwin P Bottinger, Ruth JF Loos, Girish N Nadkarni, Michael H Preuss, Adolfo Correa, Hao Mei, James Wilson, Thomas Meitinger, Martina Müller-Nurasyid, Annette Peters, Melanie Waldenberger, Massimo Mangino, Timothy D Spector, Michiel Rienstra, Yordi J van de Vegte, Pim van der Harst, Niek Verweij, Stefan Kääb, Katharina Schramm, Moritz F Sinner, Konstantin Strauch, Michael J Cutler, Diane Fatkin, Barry London, Morten Olesen, Dan M Roden, M Benjamin Shoemaker, J Gustav Smith, Mary L Biggs, Joshua C Bis, Jennifer A Brody, Bruce M Psaty, Kenneth Rice, Nona Sotoodehnia, Alessandro De Grandi, Christian Fuchsberger, Cristian Pattaro, Peter P Pramstaller, Ian Ford, J Wouter Jukema, Peter W Macfarlane, Stella Trompet, Marcus Dörr, Stephan B Felix, Uwe Völker, Stefan Weiss, Aki S Havulinna, Antti Jula, Katri Sääksjärvi, Veikko Salomaa, Xiuqing Guo, Susan R Heckbert, Henry J Lin, Jerome I Rotter, Kent D Taylor, Jie Yao, Renée de Mutsert, Arie C Maan, Dennis O Mook-Kanamori, Raymond Noordam, Francesco Cucca, Jun Ding, Edward G Lakatta, Yong Qian, Kirill V Tarasov, Daniel Levy, Honghuang Lin, Christopher H Newton-Cheh, Kathryn L Lunetta, Alison D Murray, David J Porteous, Blair H Smith, Bruno H Stricker, André Uitterlinden, Marten E van den Berg, Jeffrey Haessler, Rebecca D Jackson, Charles Kooperberg, Ulrike Peters, Alexander P Reiner, Eric A Whitsel, Alvaro Alonso, Dan E Arking, Eric Boerwinkle, Georg B Ehret, Elsayed Z Soliman, Christy L Avery, Stephanie M Gogarten, Kathleen F Kerr, Cathy C Laurie, Amanda A Seyerle, Adrienne Stilp, Solmaz Assa, M Abdullah Said, M Yldau van der Ende, Pier D Lambiase, Michele Orini, Julia Ramirez, Stefan Van Duijvenboden, David O Arnar, Daniel F Gudbjartsson, Hilma Holm, Patrick Sulem, Gudmar Thorleifsson, Rosa B Thorolfsdottir, Unnur Thorsteinsdottir, Emelia J Benjamin, Andrew Tinker, Kari Stefansson, Patrick T Ellinor, Yalda Jamshidi, Steven A Lubitz, Patricia B Munroe
Jun 08, 2020
The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality. Here we report a...
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Mary F Feitosa, Aldi T Kraja, Daniel I Chasman, Yun J Sung, Thomas W Winkler, Ioanna Ntalla, Xiuqing Guo, Nora Franceschini, Ching-Yu Cheng, Xueling Sim, Dina Vojinovic, Jonathan Marten, Solomon K Musani, Changwei Li, Amy R Bentley, Michael R Brown, Karen Schwander, Melissa A Richard, Raymond Noordam, Hugues Aschard, Traci M Bartz, Lawrence F Bielak, Rajkumar Dorajoo, Virginia Fisher, Fernando P Hartwig, Andrea RVR Horimoto, Kurt K Lohman, Alisa K Manning, Tuomo Rankinen, Albert V Smith, Salman M Tajuddin, Mary K Wojczynski, Maris Alver, Mathilde Boissel, Qiuyin Cai, Archie Campbell, Jin Fang Chai, Xu Chen, Jasmin Divers, Chuan Gao, Anuj Goel, Yanick Hagemeijer, Sarah E Harris, Meian He, Fang-Chi Hsu, Anne U Jackson, Mika Kähönen, Anuradhani Kasturiratne, Pirjo Komulainen, Brigitte Kühnel, Federica Laguzzi, Jian'an Luan, Nana Matoba, Ilja M Nolte, Sandosh Padmanabhan, Muhammad Riaz, Rico Rueedi, Antonietta Robino, M Abdullah Said, Robert A Scott, Tamar Sofer, Alena Stančáková, Fumihiko Takeuchi, Bamidele O Tayo, Peter J van der Most, Tibor V Varga, Veronique Vitart, Yajuan Wang, Erin B Ware, Helen R Warren, Stefan Weiss, Wanqing Wen, Lisa R Yanek, Weihua Zhang, Jing Hua Zhao, Saima Afaq, Najaf Amin, Marzyeh Amini, Dan E Arking, Tin Aung, Eric Boerwinkle, Ingrid Borecki, Ulrich Broeckel, Morris Brown, Marco Brumat, Gregory L Burke, Mickaël Canouil, Aravinda Chakravarti, Sabanayagam Charumathi, Yii-Der Ida Chen, John M Connell, Adolfo Correa, Lisa de Las Fuentes, Renée de Mutsert, H Janaka de Silva, Xuan Deng, Jingzhong Ding, Qing Duan, Charles B Eaton, Georg Ehret, Ruben N Eppinga, Evangelos Evangelou, Jessica D Faul, Stephan B Felix, Nita G Forouhi, Terrence Forrester, Oscar H Franco, Yechiel Friedlander, Ilaria Gandin, He Gao, Mohsen Ghanbari, Bruna Gigante, C Charles Gu, Dongfeng Gu, Saskia P Hagenaars, Göran Hallmans, Tamara B Harris, Jiang He, Sami Heikkinen, Chew-Kiat Heng, Makoto Hirata, Barbara V Howard, M Arfan Ikram, InterAct Consortium, Ulrich John, Tomohiro Katsuya, Chiea Chuen Khor, Tuomas O Kilpeläinen, Woon-Puay Koh, José E Krieger, Stephen B Kritchevsky, Michiaki Kubo, Johanna Kuusisto, Timo A Lakka, Carl D Langefeld, Claudia Langenberg, Lenore J Launer, Benjamin Lehne, Cora E Lewis, Yize Li, Shiow Lin, Jianjun Liu, Jingmin Liu, Marie Loh, Tin Louie, Reedik Mägi, Colin A McKenzie, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Lili Milani, Karen L Mohlke, Yukihide Momozawa, Mike A Nalls, Christopher P Nelson, Nona Sotoodehnia, Jill M Norris, Jeff R O'Connell, Nicholette D Palmer, Thomas Perls, Nancy L Pedersen, Annette Peters, Patricia A Peyser, Neil Poulter, Leslie J Raffel, Olli T Raitakari, Kathryn Roll, Lynda M Rose, Frits R Rosendaal, Jerome I Rotter, Carsten O Schmidt, Pamela J Schreiner, Nicole Schupf, William R Scott, Peter S Sever, Yuan Shi, Stephen Sidney, Mario Sims, Colleen M Sitlani, Jennifer A Smith, Harold Snieder, John M Starr, Konstantin Strauch, Heather M Stringham, Nicholas YQ Tan, Hua Tang, Kent D Taylor, Yik Ying Teo, Yih Chung Tham, Stephen T Turner, André G Uitterlinden, Peter Vollenweider, Melanie Waldenberger, Lihua Wang, Ya Xing Wang, Wen Bin Wei, Christine Williams, Jie Yao, Caizheng Yu, Jian-Min Yuan, Wei Zhao, Alan B Zonderman, Diane M Becker, Michael Boehnke, Donald W Bowden, John C Chambers, Ian J Deary, Tõnu Esko, Martin Farrall, Paul W Franks, Barry I Freedman, Philippe Froguel, Paolo Gasparini, Christian Gieger, Jost Bruno Jonas, Yoichiro Kamatani, Norihiro Kato, Jaspal S Kooner, Zoltán Kutalik, Markku Laakso, Cathy C Laurie, Karin Leander, Terho Lehtimäki, Lifelines Cohort Study, Patrik KE Magnusson, Albertine J Oldehinkel, Brenda WJH Penninx, Ozren Polasek, David J Porteous, Rainer Rauramaa, Nilesh J Samani, James Scott, Xiao-Ou Shu, Pim van der Harst, Lynne E Wagenknecht, Nicholas J Wareham, Hugh Watkins, David R Weir, Ananda R Wickremasinghe, Tangchun Wu, Wei Zheng, Claude Bouchard, Kaare Christensen, Michele K Evans, Vilmundur Gudnason, Bernardo L Horta, Sharon LR Kardia, Yongmei Liu, Alexandre C Pereira, Bruce M Psaty, Paul M Ridker, Rob M van Dam, W James Gauderman, Xiaofeng Zhu, Dennis O Mook-Kanamori, Myriam Fornage, Charles N Rotimi, L Adrienne Cupples, Tanika N Kelly, Ervin R Fox, Caroline Hayward, Cornelia M van Duijn, E Shyong Tai, Tien Yin Wong, Charles Kooperberg, Walter Palmas, Kenneth Rice, Alanna C Morrison, Paul Elliott, Mark J Caulfield, Patricia B Munroe, Dabeeru C Rao, Michael A Province, Daniel Levy
Oct 08, 2018
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study...
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Paul S de Vries, Michael R Brown, Amy R Bentley, Yun J Sung, Thomas W Winkler, Ioanna Ntalla, Karen Schwander, Aldi T Kraja, Xiuqing Guo, Nora Franceschini, Ching-Yu Cheng, Xueling Sim, Dina Vojinovic, Jennifer E Huffman, Solomon K Musani, Changwei Li, Mary F Feitosa, Melissa A Richard, Raymond Noordam, Hugues Aschard, Traci M Bartz, Lawrence F Bielak, Xuan Deng, Rajkumar Dorajoo, Kurt K Lohman, Alisa K Manning, Tuomo Rankinen, Albert V Smith, Salman M Tajuddin, Evangelos Evangelou, Mariaelisa Graff, Maris Alver, Mathilde Boissel, Jin Fang Chai, Xu Chen, Jasmin Divers, Ilaria Gandin, Chuan Gao, Anuj Goel, Yanick Hagemeijer, Sarah E Harris, Fernando P Hartwig, Meian He, Andrea RVR Horimoto, Fang-Chi Hsu, Anne U Jackson, Anuradhani Kasturiratne, Pirjo Komulainen, Brigitte Kühnel, Federica Laguzzi, Joseph H Lee, Jian'an Luan, Leo-Pekka Lyytikäinen, Nana Matoba, Ilja M Nolte, Maik Pietzner, Muhammad Riaz, M Abdullah Said, Robert A Scott, Tamar Sofer, Alena Stančáková, Fumihiko Takeuchi, Bamidele O Tayo, Peter J van der Most, Tibor V Varga, Yajuan Wang, Erin B Ware, Wanqing Wen, Lisa R Yanek, Weihua Zhang, Jing Hua Zhao, Saima Afaq, Najaf Amin, Marzyeh Amini, Dan E Arking, Tin Aung, Christie Ballantyne, Eric Boerwinkle, Ulrich Broeckel, Archie Campbell, Mickaël Canouil, Sabanayagam Charumathi, Yii-Der Ida Chen, John M Connell, Ulf de Faire, Lisa de Las Fuentes, Renée de Mutsert, H Janaka de Silva, Jingzhong Ding, Anna F Dominiczak, Qing Duan, Charles B Eaton, Ruben N Eppinga, Jessica D Faul, Virginia Fisher, Terrence Forrester, Oscar H Franco, Yechiel Friedlander, Mohsen Ghanbari, Franco Giulianini, Hans J Grabe, Megan L Grove, C Charles Gu, Tamara B Harris, Sami Heikkinen, Chew-Kiat Heng, Makoto Hirata, James E Hixson, Barbara V Howard, M Arfan Ikram, InterAct Consortium, David R Jacobs, Craig Johnson, Jost Bruno Jonas, Candace M Kammerer, Tomohiro Katsuya, Chiea Chuen Khor, Tuomas O Kilpeläinen, Woon-Puay Koh, Heikki A Koistinen, Ivana Kolcic, Charles Kooperberg, Jose E Krieger, Steve B Kritchevsky, Michiaki Kubo, Johanna Kuusisto, Timo A Lakka, Carl D Langefeld, Claudia Langenberg, Lenore J Launer, Benjamin Lehne, Rozenn N Lemaitre, Yize Li, Jingjing Liang, Jianjun Liu, Kiang Liu, Marie Loh, Tin Louie, Reedik Mägi, Ani W Manichaikul, Colin A McKenzie, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Lili Milani, Karen L Mohlke, Thomas H Mosley, Kenneth J Mukamal, Mike A Nalls, Matthias Nauck, Christopher P Nelson, Nona Sotoodehnia, Jeff R O'Connell, Nicholette D Palmer, Raha Pazoki, Nancy L Pedersen, Annette Peters, Patricia A Peyser, Ozren Polasek, Neil Poulter, Leslie J Raffel, Olli T Raitakari, Alex P Reiner, Treva K Rice, Stephen S Rich, Antonietta Robino, Jennifer G Robinson, Lynda M Rose, Igor Rudan, Carsten O Schmidt, Pamela J Schreiner, William R Scott, Peter Sever, Yuan Shi, Stephen Sidney, Mario Sims, Blair H Smith, Jennifer A Smith, Harold Snieder, John M Starr, Konstantin Strauch, Nicholas Tan, Kent D Taylor, Yik Ying Teo, Yih Chung Tham, André G Uitterlinden, Diana van Heemst, Dragana Vuckovic, Melanie Waldenberger, Lihua Wang, Yujie Wang, Zhe Wang, Wen Bin Wei, Christine Williams, Gregory Wilson, Mary K Wojczynski, Jie Yao, Bing Yu, Caizheng Yu, Jian-Min Yuan, Wei Zhao, Alan B Zonderman, Diane M Becker, Michael Boehnke, Donald W Bowden, John C Chambers, Ian J Deary, Tõnu Esko, Martin Farrall, Paul W Franks, Barry I Freedman, Philippe Froguel, Paolo Gasparini, Christian Gieger, Bernardo L Horta, Yoichiro Kamatani, Norihiro Kato, Jaspal S Kooner, Markku Laakso, Karin Leander, Terho Lehtimäki, Groningen, The Netherlands (Lifelines Cohort Study) Lifelines Cohort, Patrik KE Magnusson, Brenda Penninx, Alexandre C Pereira, Rainer Rauramaa, Nilesh J Samani, James Scott, Xiao-Ou Shu, Pim van der Harst, Lynne E Wagenknecht, Ya Xing Wang, Nicholas J Wareham, Hugh Watkins, David R Weir, Ananda R Wickremasinghe, Wei Zheng, Paul Elliott, Kari E North, Claude Bouchard, Michele K Evans, Vilmundur Gudnason, Ching-Ti Liu, Yongmei Liu, Bruce M Psaty, Paul M Ridker, Rob M van Dam, Sharon LR Kardia, Xiaofeng Zhu, Charles N Rotimi, Dennis O Mook-Kanamori, Myriam Fornage, Tanika N Kelly, Ervin R Fox, Caroline Hayward, Cornelia M van Duijn, E Shyong Tai, Tien Yin Wong, Jingmin Liu, Jerome I Rotter, W James Gauderman, Michael A Province, Patricia B Munroe, Kenneth Rice, Daniel I Chasman, L Adrienne Cupples, Dabeeru C Rao, Alanna C Morrison
Feb 18, 2019
A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions into a...
alcohol consumption Cholesterol gene-environment interactions gene-lifestyle interactions genome-wide association studies Lipids Triglycerides Adolescent Adult Aged Alcohol Drinking Cholesterol HDL Cholesterol LDL Female Genome-Wide Association Study Genotype Humans Life Style Lipids Male Middle Aged Phenotype Racial Groups Triglycerides Vascular Endothelial Growth Factor B Young Adult
Associations of autozygosity with a broad range of human phenotypes
David W Clark, Yukinori Okada, Kristjan H S Moore, Dan Mason, Nicola Pirastu, Ilaria Gandin, Hannele Mattsson, Catriona L K Barnes, Kuang Lin, Jing Hua Zhao, Patrick Deelen, Rebecca Rohde, Claudia Schurmann, Xiuqing Guo, Franco Giulianini, Weihua Zhang, Carolina Medina-Gomez, Robert Karlsson, Yanchun Bao, Traci M Bartz, Clemens Baumbach, Ginevra Biino, Matthew J Bixley, Marco Brumat, Jin-Fang Chai, Tanguy Corre, Diana L Cousminer, Annelot M Dekker, David A Eccles, Kristel R van Eijk, Christian Fuchsberger, He Gao, Marine Germain, Scott D Gordon, Hugoline G de Haan, Sarah E Harris, Edith Hofer, Alicia Huerta-Chagoya, Catherine Igartua, Iris E Jansen, Yucheng Jia, Tim Kacprowski, Torgny Karlsson, Marcus E Kleber, Shengchao Alfred Li, Ruifang Li-Gao, Anubha Mahajan, Koichi Matsuda, Karina Meidtner, Weihua Meng, May E Montasser, Peter J van der Most, Matthias Munz, Teresa Nutile, Teemu Palviainen, Gauri Prasad, Rashmi B Prasad, Tallapragada Divya Sri Priyanka, Federica Rizzi, Erika Salvi, Bishwa R Sapkota, Daniel Shriner, Line Skotte, Melissa C Smart, Albert Vernon Smith, Ashley van der Spek, Cassandra N Spracklen, Rona J Strawbridge, Salman M Tajuddin, Stella Trompet, Constance Turman, Niek Verweij, Clara Viberti, Lihua Wang, Helen R Warren, Robyn E Wootton, Lisa R Yanek, Jie Yao, Noha A Yousri, Wei Zhao, Adebowale A Adeyemo, Saima Afaq, Carlos Alberto Aguilar-Salinas, Masato Akiyama, Matthew L Albert, Matthew A Allison, Maris Alver, Tin Aung, Fereidoun Azizi, Amy R Bentley, Heiner Boeing, Eric Boerwinkle, Judith B Borja, Gert J de Borst, Erwin P Bottinger, Linda Broer, Harry Campbell, Stephen Chanock, Miao-Li Chee, Guanjie Chen, Yii-Der I Chen, Zhengming Chen, Yen-Feng Chiu, Massimiliano Cocca, Francis S Collins, Maria Pina Concas, Janie Corley, Giovanni Cugliari, Rob M van Dam, Anna Damulina, Maryam S Daneshpour, Felix R Day, Graciela E Delgado, Klodian Dhana, Alexander S F Doney, Marcus Dörr, Ayo P Doumatey, Nduna Dzimiri, S Sunna Ebenesersdóttir, Joshua Elliott, Paul Elliott, Ralf Ewert, Janine F Felix, Krista Fischer, Barry I Freedman, Giorgia Girotto, Anuj Goel, Martin Gögele, Mark O Goodarzi, Mariaelisa Graff, Einat Granot-Hershkovitz, Francine Grodstein, Simonetta Guarrera, Daniel F Gudbjartsson, Kamran Guity, Bjarni Gunnarsson, Yu Guo, Saskia P Hagenaars, Christopher A Haiman, Avner Halevy, Tamara B Harris, Mehdi Hedayati, David A van Heel, Makoto Hirata, Imo Höfer, Chao Agnes Hsiung, Jinyan Huang, Yi-Jen Hung, M Arfan Ikram, Anuradha Jagadeesan, Pekka Jousilahti, Yoichiro Kamatani, Masahiro Kanai, Nicola D Kerrison, Thorsten Kessler, Kay-Tee Khaw, Chiea Chuen Khor, Dominique P V de Kleijn, Woon-Puay Koh, Ivana Kolcic, Peter Kraft, Bernhard K Krämer, Zoltán Kutalik, Johanna Kuusisto, Claudia Langenberg, Lenore J Launer, Deborah A Lawlor, I-Te Lee, Wen-Jane Lee, Markus M Lerch, Liming Li, Jianjun Liu, Marie Loh, Stephanie J London, Stephanie Loomis, Yingchang Lu, Jian’an Luan, Reedik Mägi, Ani W Manichaikul, Paolo Manunta, Gísli Másson, Nana Matoba, Xue W Mei, Christa Meisinger, Thomas Meitinger, Massimo Mezzavilla, Lili Milani, Iona Y Millwood, Yukihide Momozawa, Amy Moore, Pierre-Emmanuel Morange, Hortensia Moreno-Macías, Trevor A Mori, Alanna C Morrison, Taulant Muka, Yoshinori Murakami, Alison D Murray, Renée de Mutsert, Josyf C Mychaleckyj, Mike A Nalls, Matthias Nauck, Matt J Neville, Ilja M Nolte, Ken K Ong, Lorena Orozco, Sandosh Padmanabhan, Gunnar Pálsson, James S Pankow, Cristian Pattaro, Alison Pattie, Ozren Polasek, Neil Poulter, Peter P Pramstaller, Lluis Quintana-Murci, Katri Räikkönen, Sarju Ralhan, Dabeeru C Rao, Wouter Van Rheenen, Stephen S Rich, Paul M Ridker, Cornelius A Rietveld, Antonietta Robino, Frank J A van Rooij, Daniela Ruggiero, Yasaman Saba, Charumathi Sabanayagam, Maria Sabater-Lleal, Cinzia Felicita Sala, Veikko Salomaa, Kevin Sandow, Helena Schmidt, Laura J Scott, William R Scott, Bahareh Sedaghati-Khayat, Bengt Sennblad, Jessica van Setten, Peter J Sever, Wayne H-H Sheu, Yuan Shi, Smeeta Shrestha, Sharvari Rahul Shukla, Jon K Sigurdsson, Timo Tonis Sikka, Jai Rup Singh, Blair H Smith, Alena Stančáková, Alice Stanton, John M Starr, Lilja Stefansdottir, Leon Straker, Patrick Sulem, Gardar Sveinbjornsson, Morris A Swertz, Adele M Taylor, Kent D Taylor, Natalie Terzikhan, Yih-Chung Tham, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Annika Tillander, Russell P Tracy, Teresa Tusié-Luna, Ioanna Tzoulaki, Simona Vaccargiu, Jagadish Vangipurapu, Jan H Veldink, Veronique Vitart, Uwe Völker, Eero Vuoksimaa, Salma M Wakil, Melanie Waldenberger, Gurpreet S Wander, Ya Xing Wang, Nicholas J Wareham, Sarah Wild, Chittaranjan S Yajnik, Jian-Min Yuan, Lingyao Zeng, Liang Zhang, Jie Zhou, Najaf Amin, Folkert W Asselbergs, Stephan J L Bakker, Diane M Becker, Benjamin Lehne, David A Bennett, Leonard H Van den Berg, Sonja I Berndt, Dwaipayan Bharadwaj, Lawrence F Bielak, Murielle Bochud, Mike Boehnke, Claude Bouchard, Jonathan P Bradfield, Jennifer A Brody, Archie Campbell, Shai Carmi, Mark J Caulfield, David Cesarini, John C Chambers, Giriraj Ratan Chandak, Ching-Yu Cheng, Marina Ciullo, Marilyn Cornelis, Daniele Cusi, George Davey Smith, Ian J Deary, Rajkumar Dorajoo, Cornelia M van Duijn, David Ellinghaus, Jeanette Erdmann, Johan G Eriksson, Evangelos Evangelou, Michele K Evans, Jessica D Faul, Bjarke Feenstra, Mary Feitosa, Sylvain Foisy, Andre Franke, Yechiel Friedlander, Paolo Gasparini, Christian Gieger, Clicerio Gonzalez, Philippe Goyette, Struan F A Grant, Lyn R Griffiths, Leif Groop, Vilmundur Gudnason, Ulf Gyllensten, Hakon Hakonarson, Anders Hamsten, Pim van der Harst, Chew-Kiat Heng, Andrew A Hicks, Hagit Hochner, Heikki Huikuri, Steven C Hunt, Vincent W V Jaddoe, Philip L De Jager, Magnus Johannesson, Åsa Johansson, Jost B Jonas, J Wouter Jukema, Juhani Junttila, Jaakko Kaprio, Sharon L. R. Kardia, Fredrik Karpe, Meena Kumari, Markku Laakso, Sander W van der Laan, Jari Lahti, Matthias Laudes, Rodney A Lea, Wolfgang Lieb, Thomas Lumley, Nicholas G Martin, Winfried März, Giuseppe Matullo, Mark I McCarthy, Sarah E Medland, Tony R Merriman, Andres Metspalu, Brian F Meyer, Karen L Mohlke, Grant W Montgomery, Dennis Mook-Kanamori, Patricia B Munroe, Kari E North, Dale R Nyholt, Jeffery R O’connell, Carole Ober, Albertine J Oldehinkel, Walter Palmas, Colin Palmer, Gerard G Pasterkamp, Etienne Patin, Craig E Pennell, Louis Perusse, Patricia A Peyser, Mario Pirastu, Tinca J. C. Polderman, David J Porteous, Danielle Posthuma, Bruce M Psaty, John D Rioux, Fernando Rivadeneira, Charles Rotimi, Jerome I Rotter, Igor Rudan, Hester M den Ruijter, Dharambir K Sanghera, Naveed Sattar, Reinhold Schmidt, Matthias B Schulze, Heribert Schunkert, Robert A Scott, Alan R Shuldiner, Xueling Sim, Neil Small, Jennifer A Smith, Nona Sotoodehnia, E-Shyong Tai, Alexander Teumer, Nicholas J Timpson, Daniela Toniolo, David-Alexandre Tregouet, Tiinamaija Tuomi, Peter Vollenweider, Carol A Wang, David R Weir, John B Whitfield, Cisca Wijmenga, Tien-Yin Wong, John Wright, Jingyun Yang, Lei Yu, Babette S Zemel, Alan B Zonderman, Markus Perola, Patrik K. E. Magnusson, André G Uitterlinden, Jaspal S Kooner, Daniel I Chasman, Ruth J. F. Loos, Nora Franceschini, Lude Franke, Chris S Haley, Caroline Hayward, Robin G Walters, John R. B. Perry, Tōnu Esko, Agnar Helgason, Kari Stefansson, Peter K Joshi, Michiaki Kubo, James F Wilson
Oct 31, 2020
Abstract: In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because...
Associations of autozygosity with a broad range of human phenotypes.
David W Clark, Yukinori Okada, Kristjan HS Moore, Dan Mason, Nicola Pirastu, Ilaria Gandin, Hannele Mattsson, Catriona LK Barnes, Kuang Lin, Jing Hua Zhao, Patrick Deelen, Rebecca Rohde, Claudia Schurmann, Xiuqing Guo, Franco Giulianini, Weihua Zhang, Carolina Medina-Gomez, Robert Karlsson, Yanchun Bao, Traci M Bartz, Clemens Baumbach, Ginevra Biino, Matthew J Bixley, Marco Brumat, Jin-Fang Chai, Tanguy Corre, Diana L Cousminer, Annelot M Dekker, David A Eccles, Kristel R van Eijk, Christian Fuchsberger, He Gao, Marine Germain, Scott D Gordon, Hugoline G de Haan, Sarah E Harris, Edith Hofer, Alicia Huerta-Chagoya, Catherine Igartua, Iris E Jansen, Yucheng Jia, Tim Kacprowski, Torgny Karlsson, Marcus E Kleber, Shengchao Alfred Li, Ruifang Li-Gao, Anubha Mahajan, Koichi Matsuda, Karina Meidtner, Weihua Meng, May E Montasser, Peter J van der Most, Matthias Munz, Teresa Nutile, Teemu Palviainen, Gauri Prasad, Rashmi B Prasad, Tallapragada Divya Sri Priyanka, Federica Rizzi, Erika Salvi, Bishwa R Sapkota, Daniel Shriner, Line Skotte, Melissa C Smart, Albert Vernon Smith, Ashley van der Spek, Cassandra N Spracklen, Rona J Strawbridge, Salman M Tajuddin, Stella Trompet, Constance Turman, Niek Verweij, Clara Viberti, Lihua Wang, Helen R Warren, Robyn E Wootton, Lisa R Yanek, Jie Yao, Noha A Yousri, Wei Zhao, Adebowale A Adeyemo, Saima Afaq, Carlos Alberto Aguilar-Salinas, Masato Akiyama, Matthew L Albert, Matthew A Allison, Maris Alver, Tin Aung, Fereidoun Azizi, Amy R Bentley, Heiner Boeing, Eric Boerwinkle, Judith B Borja, Gert J de Borst, Erwin P Bottinger, Linda Broer, Harry Campbell, Stephen Chanock, Miao-Li Chee, Guanjie Chen, Yii-Der I Chen, Zhengming Chen, Yen-Feng Chiu, Massimiliano Cocca, Francis S Collins, Maria Pina Concas, Janie Corley, Giovanni Cugliari, Rob M van Dam, Anna Damulina, Maryam S Daneshpour, Felix R Day, Graciela E Delgado, Klodian Dhana, Alexander SF Doney, Marcus Dörr, Ayo P Doumatey, Nduna Dzimiri, S Sunna Ebenesersdóttir, Joshua Elliott, Paul Elliott, Ralf Ewert, Janine F Felix, Krista Fischer, Barry I Freedman, Giorgia Girotto, Anuj Goel, Martin Gögele, Mark O Goodarzi, Mariaelisa Graff, Einat Granot-Hershkovitz, Francine Grodstein, Simonetta Guarrera, Daniel F Gudbjartsson, Kamran Guity, Bjarni Gunnarsson, Yu Guo, Saskia P Hagenaars, Christopher A Haiman, Avner Halevy, Tamara B Harris, Mehdi Hedayati, David A van Heel, Makoto Hirata, Imo Höfer, Chao Agnes Hsiung, Jinyan Huang, Yi-Jen Hung, M Arfan Ikram, Anuradha Jagadeesan, Pekka Jousilahti, Yoichiro Kamatani, Masahiro Kanai, Nicola D Kerrison, Thorsten Kessler, Kay-Tee Khaw, Chiea Chuen Khor, Dominique PV de Kleijn, Woon-Puay Koh, Ivana Kolcic, Peter Kraft, Bernhard K Krämer, Zoltán Kutalik, Johanna Kuusisto, Claudia Langenberg, Lenore J Launer, Deborah A Lawlor, I-Te Lee, Wen-Jane Lee, Markus M Lerch, Liming Li, Jianjun Liu, Marie Loh, Stephanie J London, Stephanie Loomis, Yingchang Lu, Jian'an Luan, Reedik Mägi, Ani W Manichaikul, Paolo Manunta, Gísli Másson, Nana Matoba, Xue W Mei, Christa Meisinger, Thomas Meitinger, Massimo Mezzavilla, Lili Milani, Iona Y Millwood, Yukihide Momozawa, Amy Moore, Pierre-Emmanuel Morange, Hortensia Moreno-Macías, Trevor A Mori, Alanna C Morrison, Taulant Muka, Yoshinori Murakami, Alison D Murray, Renée de Mutsert, Josyf C Mychaleckyj, Mike A Nalls, Matthias Nauck, Matt J Neville, Ilja M Nolte, Ken K Ong, Lorena Orozco, Sandosh Padmanabhan, Gunnar Pálsson, James S Pankow, Cristian Pattaro, Alison Pattie, Ozren Polasek, Neil Poulter, Peter P Pramstaller, Lluis Quintana-Murci, Katri Räikkönen, Sarju Ralhan, Dabeeru C Rao, Wouter Van Rheenen, Stephen S Rich, Paul M Ridker, Cornelius A Rietveld, Antonietta Robino, Frank JA van Rooij, Daniela Ruggiero, Yasaman Saba, Charumathi Sabanayagam, Maria Sabater-Lleal, Cinzia Felicita Sala, Veikko Salomaa, Kevin Sandow, Helena Schmidt, Laura J Scott, William R Scott, Bahareh Sedaghati-Khayat, Bengt Sennblad, Jessica van Setten, Peter J Sever, Wayne H-H Sheu, Yuan Shi, Smeeta Shrestha, Sharvari Rahul Shukla, Jon K Sigurdsson, Timo Tonis Sikka, Jai Rup Singh, Blair H Smith, Alena Stančáková, Alice Stanton, John M Starr, Lilja Stefansdottir, Leon Straker, Patrick Sulem, Gardar Sveinbjornsson, Morris A Swertz, Adele M Taylor, Kent D Taylor, Natalie Terzikhan, Yih-Chung Tham, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Annika Tillander, Russell P Tracy, Teresa Tusié-Luna, Ioanna Tzoulaki, Simona Vaccargiu, Jagadish Vangipurapu, Jan H Veldink, Veronique Vitart, Uwe Völker, Eero Vuoksimaa, Salma M Wakil, Melanie Waldenberger, Gurpreet S Wander, Ya Xing Wang, Nicholas J Wareham, Sarah Wild, Chittaranjan S Yajnik, Jian-Min Yuan, Lingyao Zeng, Liang Zhang, Jie Zhou, Najaf Amin, Folkert W Asselbergs, Stephan JL Bakker, Diane M Becker, Benjamin Lehne, David A Bennett, Leonard H Van den Berg, Sonja I Berndt, Dwaipayan Bharadwaj, Lawrence F Bielak, Murielle Bochud, Mike Boehnke, Claude Bouchard, Jonathan P Bradfield, Jennifer A Brody, Archie Campbell, Shai Carmi, Mark J Caulfield, David Cesarini, John C Chambers, Giriraj Ratan Chandak, Ching-Yu Cheng, Marina Ciullo, Marilyn Cornelis, Daniele Cusi, George Davey Smith, Ian J Deary, Rajkumar Dorajoo, Cornelia M van Duijn, David Ellinghaus, Jeanette Erdmann, Johan G Eriksson, Evangelos Evangelou, Michele K Evans, Jessica D Faul, Bjarke Feenstra, Mary Feitosa, Sylvain Foisy, Andre Franke, Yechiel Friedlander, Paolo Gasparini, Christian Gieger, Clicerio Gonzalez, Philippe Goyette, Struan FA Grant, Lyn R Griffiths, Leif Groop, Vilmundur Gudnason, Ulf Gyllensten, Hakon Hakonarson, Anders Hamsten, Pim van der Harst, Chew-Kiat Heng, Andrew A Hicks, Hagit Hochner, Heikki Huikuri, Steven C Hunt, Vincent WV Jaddoe, Philip L De Jager, Magnus Johannesson, Åsa Johansson, Jost B Jonas, J Wouter Jukema, Juhani Junttila, Jaakko Kaprio, Sharon LR Kardia, Fredrik Karpe, Meena Kumari, Markku Laakso, Sander W van der Laan, Jari Lahti, Matthias Laudes, Rodney A Lea, Wolfgang Lieb, Thomas Lumley, Nicholas G Martin, Winfried März, Giuseppe Matullo, Mark I McCarthy, Sarah E Medland, Tony R Merriman, Andres Metspalu, Brian F Meyer, Karen L Mohlke, Grant W Montgomery, Dennis Mook-Kanamori, Patricia B Munroe, Kari E North, Dale R Nyholt, Jeffery R O'connell, Carole Ober, Albertine J Oldehinkel, Walter Palmas, Colin Palmer, Gerard G Pasterkamp, Etienne Patin, Craig E Pennell, Louis Perusse, Patricia A Peyser, Mario Pirastu, Tinca JC Polderman, David J Porteous, Danielle Posthuma, Bruce M Psaty, John D Rioux, Fernando Rivadeneira, Charles Rotimi, Jerome I Rotter, Igor Rudan, Hester M den Ruijter, Dharambir K Sanghera, Naveed Sattar, Reinhold Schmidt, Matthias B Schulze, Heribert Schunkert, Robert A Scott, Alan R Shuldiner, Xueling Sim, Neil Small, Jennifer A Smith, Nona Sotoodehnia, E-Shyong Tai, Alexander Teumer, Nicholas J Timpson, Daniela Toniolo, David-Alexandre Tregouet, Tiinamaija Tuomi, Peter Vollenweider, Carol A Wang, David R Weir, John B Whitfield, Cisca Wijmenga, Tien-Yin Wong, John Wright, Jingyun Yang, Lei Yu, Babette S Zemel, Alan B Zonderman, Markus Perola, Patrik KE Magnusson, André G Uitterlinden, Jaspal S Kooner, Daniel I Chasman, Ruth JF Loos, Nora Franceschini, Lude Franke, Chris S Haley, Caroline Hayward, Robin G Walters, John RB Perry, Tōnu Esko, Agnar Helgason, Kari Stefansson, Peter K Joshi, Michiaki Kubo, James F Wilson
Sep 13, 2021
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction...