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A multicentre, randomised controlled trial to compare the clinical and cost-effectiveness of Lee Silverman Voice Treatment versus standard NHS Speech and Language Therapy versus control in Parkinson's disease
CM Sackley, C Rick, P Au, MC Brady, G Beaton, C Burton, M Caulfield, S Dickson, F Dowling, M Hughes, N Ives, S Jowett, P Masterson-Algar, A Nicoll, S Patel, CH Smith, R Woolley, CE Clarke, PD COMM Collaborative Group
May 27, 2021
BACKGROUND: Parkinson's disease (PD) affects approximately 145,519 people in the UK. Speech impairments are common with a reported prevalence of 68%, which increase physical and mental demands during conversation, reliance on...
dysarthria Idiopathic Parkinson’s disease Lee Silverman voice treatment randomised controlled trial speech and language therapy Clinical Trials Phase III as Topic Cost-Benefit Analysis Humans Language Therapy Multicenter Studies as Topic Parkinson Disease Quality of life Randomized Controlled Trials as Topic speech therapy Surveys and Questionnaires United Kingdom Voice Voice Disorders
Which Neuropsychological Tests? Predicting Cognitive Decline and Dementia in Parkinson's Disease in the ICICLE-PD Cohort.
Rachael A Lawson, Caroline H Williams-Gray, Marta Camacho, Gordon W Duncan, Tien K Khoo, David P Breen, Roger A Barker, Lynn Rochester, David J Burn, Alison J Yarnall, ICICLE-PD study group
May 28, 2021
BACKGROUND: Cognitive impairment is common in Parkinson's disease (PD), with 80% cumulatively developing dementia (PDD). OBJECTIVE: We sought to identify tests that are sensitive to change over time above normal ageing so as to...
Cognitive decline and quality of life in incident Parkinson's disease
Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, David P Breen, Tien K Khoo, Caroline H Williams-Gray, Roger A Barker, Daniel Collerton, John-Paul Taylor, David J Burn, ICICLE-PD study group
Apr 12, 2018
INTRODUCTION: Parkinson's disease dementia (PDD) is associated with poorer quality of life (QoL). Prior to the onset of PDD, many patients experience progressive cognitive impairment. There is a paucity of longitudinal studies...
Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries
Mindy Goldman, Marc Germain, Yves Grégoire, Ralph R Vassallo, Hany Kamel, Marjorie Bravo, David O Irving, Emanuele Di Angelantonio, Whitney R Steele, Sheila F O'Brien, Biomedical Excellence for Safer Transfusion Collaborative (BEST) Investigators
Jan 29, 2019
BACKGROUND: Some countries impose an upper age limit on whole blood and double RBC donation while others do not. We evaluated the safety of blood donation in older individuals (≥71 years), and their contribution to the blood...
The British Neurosurgical Trainee Research Collaborative
Aswin Chari, Aimun A Jamjoom, Ellie Edlmann, Aminul I Ahmed, Ian C Coulter, Ruichong Ma, Paul May, Paul M Brennan, Peter JA Hutchinson, Angelos G Kolias, British Neurosurgical Trainee Research Collaborative
Nov 28, 2018
Since its inception in 2012, the British Neurosurgical Trainee Research Collaborative (BNTRC) has established itself as a robust example of a trainee-led research collaborative. This article summarises the work of the...
Cognitive impairment in Parkinson's disease
RA Lawson, AJ Yarnall, F Johnston, GW Duncan, TK Khoo, D Collerton, JP Taylor, DJ Burn, ICICLE-PD study group
Apr 12, 2018
BACKGROUND: The quality of life (QoL) of informal caregivers of people with Parkinson's disease (PD) (PwP) can be affected by the caring role. Because of cognitive symptoms and diminished activities of daily living, in addition...
Effectiveness of a quality improvement collaborative in reducing time to surgery for patients requiring emergency cholecystectomy.
JR Bamber, TJ Stephens, DA Cromwell, E Duncan, GP Martin, NF Quiney, JF Abercrombie, IJ Beckingham, Cholecystectomy Quality Improvement Collaborative
Oct 11, 2019
BACKGROUND: Acute gallstone disease is a high-volume emergency general surgery presentation with wide variations in the quality of care provided across the UK. This controlled cohort evaluation assessed whether participation in...
Stability of mild cognitive impairment in newly diagnosed Parkinson's disease.
Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, David P Breen, Tien K Khoo, Caroline H Williams-Gray, Roger A Barker, David J Burn, ICICLE-PD study group
Aug 16, 2017
BACKGROUND: Mild cognitive impairment (MCI) is common in early Parkinson's disease (PD). We evaluated the stability of PD-MCI over time to determine its clinical utility as a marker of disease. METHODS: 212 newly diagnosed...
Anxiety is associated with cognitive impairment in newly-diagnosed Parkinson's disease.
Nadeeka NW Dissanayaka, Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, David P Breen, Tien K Khoo, Roger A Barker, David J Burn, ICICLE-PD study group
Aug 17, 2017
INTRODUCTION: Anxiety and mild cognitive impairment (MCI) are prevalent non-motor manifestations of Parkinson's disease (PD). While few studies have demonstrated a possible link between cognitive dysfunction and anxiety in PD...
Collaborative Writing in the Intelligence Community
With new and evolving technology and ever-increasing remote collaboration, intelligence reporting processes are at a crossroads. Key questions about how best to collaboratively produce reports to get the right information to the...
Published by: IGI Global Scientific Publishing
Research in progress--LungSEARCH
UNLABELLED: Low-dose CT screening for lung cancer is effective but expensive. Therefore, cheaper or more focused screening strategies may be required. LungSEARCH is a randomised prospective trial of 1568 high-risk individuals...
Collaborative facilitation and collaborative inhibition in virtual environments
Worldwide, organizations and small and medium-sized enterprises have already disruptively changed in many ways their physiological inner mechanisms, because of information and communication technologies (ICT) revolution....
Winthrop Mass Comm Major Awarded Grant to Study in Germany
Winthrop University
Jan 01, 0001
Sweatt will use the $2,500 grant to study abroad in Germany in summer 2016. The mass comm major grew up in Germany and Columbia, South Carolina.
Published by: Winthrop University
Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease
Cristina Nombela, James B Rowe, Sophie E Winder-Rhodes, Adam Hampshire, Adrian M Owen, David P Breen, Gordon W Duncan, Tien K Khoo, Alison J Yarnall, Michael J Firbank, Patrick F Chinnery, Trevor W Robbins, John T O'Brien, David J Brooks, David J Burn, ICICLE-PD study group, Roger A Barker
Feb 02, 2016
Parkinson’s disease Cognition Functional MRI Genetics Aged Apolipoproteins E Brain Catechol O-Methyltransferase Cognition Cognition Disorders Cohort Studies Female Humans Image Processing Computer-Assisted Imagination Longitudinal Studies Magnetic Resonance Imaging Male Memory Middle Aged Mitogen-Activated Protein Kinases Neuroimaging Neuropsychological Tests Parkinson Disease Psychomotor Performance Rotation Space Perception tau Proteins
Collaborative creativity in instrumental group music learning as a site for enhancing pupil wellbeing
This study explores the nature of the elements that co-influence collaborative creativity in instrumental group music learning and the intrinsic potential for enhancing pupil wellbeing as evidenced in a particular...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
Embracing Monogenic Parkinson's Disease
Eva-Juliane Vollstedt, Susen Schaake, Katja Lohmann, Shalini Padmanabhan, Alexis Brice, Suzanne Lesage, Christelle Tesson, Marie Vidailhet, Isabel Wurster, Faycel Hentati, Anat Mirelman, Nir Giladi, Karen Marder, Cheryl Waters, Stanley Fahn, Meike Kasten, Norbert Brüggemann, Max Borsche, Tatiana Foroud, Eduardo Tolosa, Alicia Garrido, Grazia Annesi, Monica Gagliardi, Maria Bozi, Leonidas Stefanis, Joaquim J Ferreira, Leonor Correia Guedes, Micol Avenali, Simona Petrucci, Lorraine Clark, Ekaterina Y Fedotova, Natalya Y Abramycheva, Victoria Alvarez, Manuel Menéndez-González, Silvia Jesús Maestre, Pilar Gómez-Garre, Pablo Mir, Andrea Carmine Belin, Caroline Ran, Chin-Hsien Lin, Ming-Che Kuo, David Crosiers, Zbigniew K Wszolek, Owen A Ross, Joseph Jankovic, Kenya Nishioka, Manabu Funayama, Jordi Clarimon, Caroline H Williams-Gray, Marta Camacho, Mario Cornejo-Olivas, Luis Torres-Ramirez, Yih-Ru Wu, Guey-Jen Lee-Chen, Ana Morgadinho, Teeratorn Pulkes, Pichet Termsarasab, Daniela Berg, Gregor Kuhlenbäumer, Andrea A Kühn, Friederike Borngräber, Giuseppe de Michele, Anna De Rosa, Alexander Zimprich, Andreas Puschmann, George D Mellick, Jolanta Dorszewska, Jonathan Carr, Rosangela Ferese, Stefano Gambardella, Bruce Chase, Katerina Markopoulou, Wataru Satake, Tatsushi Toda, Malco Rossi, Marcelo Merello, Timothy Lynch, Diana A Olszewska, Shen-Yang Lim, Azlina Ahmad-Annuar, Ai Huey Tan, Bashayer Al-Mubarak, Hasmet Hanagasi, Dariusz Koziorowski, Sibel Ertan, Gençer Genç, Patricia de Carvalho Aguiar, Melinda Barkhuizen, Marcia MG Pimentel, Rachel Saunders-Pullman, Bart van de Warrenburg, Susan Bressman, Mathias Toft, Silke Appel-Cresswell, Anthony E Lang, Matej Skorvanek, Agnita JW Boon, Rejko Krüger, Esther M Sammler, Vitor Tumas, Bao-Rong Zhang, Gaetan Garraux, Sun Ju Chung, Yun Joong Kim, Juliane Winkelmann, Carolyn M Sue, Eng-King Tan, Joana Damásio, Péter Klivényi, Vladimir S Kostic, David Arkadir, Mika Martikainen, Vanderci Borges, Jens Michael Hertz, Laura Brighina, Mariana Spitz, Oksana Suchowersky, Olaf Riess, Parimal Das, Brit Mollenhauer, Emilia M Gatto, Maria Skaalum Petersen, Nobutaka Hattori, Ruey-Meei Wu, Sergey N Illarioshkin, Enza Maria Valente, Jan O Aasly, Anna Aasly, Roy N Alcalay, Avner Thaler, Matthew J Farrer, Kathrin Brockmann, Jean-Christophe Corvol, Christine Klein, MJFF Global Genetic Parkinson's Disease Study Group
Jan 24, 2023
BACKGROUND: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the...
Teachers' Attitudes Towards the Effectiveness of Collaborative Reflection Support Method
This study aimed to explore how minute paper method (MPM) reconstructs the attitude towards the collaborative reflection among ten primary school English teachers with different levels of achievement goal (AG) and community...
Published by: IGI Global Scientific Publishing
Cinnamaldehyde hydrogenation using Au–Pd catalysts prepared by sol immobilisation
Stefano Cattaneo, Simon J Freakley, David J Morgan, Meenakshisundaram Sankar, Nikolaos Dimitratos, Graham J Hutchings
Mar 21, 2018
We report the catalytic performance of Au–Pd nanoparticles prepared via a sol immobilisation technique for the catalytic hydrogenation of cinnamaldehyde under mild reaction conditions. We synthesised a series of bimetallic Au–Pd...
Effects of Different Leadership Styles on Cognitive Engagement in Online Collaborative Learning
The collaborative learning approach as a universal teaching strategy is widely used in online learning. It is proven that the group leader has an important impact on group collaborative knowledge construction in online...
Published by: IGI Global Scientific Publishing
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
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