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The Ursinus College Investment Management Company Newsletter, Spring 2021
Inside this issue:
Letter from Kareem Elghawy '22
Letter from Wendy Luo '21
At a Glance
Investment Strategies
Endowment at Work
UCIMCO Updates
Fall Semester Investment Performance
Endowment Outlook
Stock Selection Picks
Women's...
UCIMCO Endowment portfolio management stock selection Investment performance Ursinus College Business Finance and Financial Management Portfolio and Security Analysis
Published by: Ursinus College
Why is reporting quality improvement so hard? A qualitative study in perioperative care.
OBJECTIVES: Quality improvement (QI) may help to avert or mitigate the risks of suboptimal care, but it is often poorly reported in the healthcare literature. We aimed to identify the influences on reporting QI in the area of...
The Application of Big Data and Artificial Intelligence Technology in Enterprise Information Security Management and Risk Assessment
With the development of digitalization and Internet technology, enterprise information security is facing more and more challenges. Many enterprises have begun to adopt big data (BD) and artificial intelligence (AI) technology...
Published by: IGI Global Scientific Publishing
Determining the skills needed by frontline NHS staff to deliver quality improvement
BACKGROUND: Previous studies have detailed the technical, learning and soft skills healthcare staff deploy to deliver quality improvement (QI). However, research has mainly focused on management and leadership skills...
Marmoset Viral Hepatic Inflammation Induced by Hepatitis C Virus Core Protein via IL-32.
Bochao Liu, Xiaorui Ma, Qi Wang, Shengxue Luo, Ling Zhang, Wenjing Wang, Yongshui Fu, Jean-Pierre Allain, Chengyao Li, Tingting Li
May 05, 2020
Common marmosets infected with GB virus-B (GBV-B) chimeras containing hepatitis C virus (HCV) core and envelope proteins (CE1E2p7) developed more severe hepatitis than those infected with HCV envelope proteins (E1E2p7)...
A Board Level Intervention to Develop Organisation-Wide Quality Improvement Strategies
Estela Capelas Barbosa, Lorelei Jones, Linda Pomeroy, Glenn Robert, Susan Burnett, Janet E Anderson, Steve Morris, Fulop Naomi
Aug 26, 2020
BACKGROUND: Hospital boards have statutory responsibility for upholding the quality of care in their organisations. International research on quality in hospitals resulted in a research-based guide to help senior hospital...
A Truss-Based Framework for Graph Similarity Computation
The study of graph kernels has been an important area of graph analysis, which is widely used to solve the similarity problems between graphs. Most of the existing graph kernels consider either local or global properties of the...
Published by: IGI Global Scientific Publishing
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Feb 15, 2020
BACKGROUND:The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Published by: BMC medical research methodology
Long-Term-Oriented Values, Governance Model Preferences, and Dual Innovation in Family Firms
A total of 217 questionnaires were used to empirically test the mechanism and effect of long-term orientation and governance mode preference on dual innovation in family firms. The data analysis shows that family firms'...
Published by: IGI Global Scientific Publishing
Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications.
Wei Wu, Li Luo, Yi Wang, Qi Wu, Han-Bin Dai, Jian-Shu Li, Colm Durkan, Nan Wang, Gui-Xue Wang
Apr 05, 2018
Nanotechnology-based antitumor drug delivery systems, known as nanocarriers, have demonstrated their efficacy in recent years. Typically, the size of the nanocarriers is around 100 nm. It is imperative to achieve an optimum size...
Mapping outcomes in quality improvement and system design activities
BACKGROUND: Whether explicit or implicit, models of value are fundamental in quality improvement (QI) initiatives. They embody the desirability of the impact of interventions-with either foresight or hindsight. Increasingly...
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Jan 20, 2020
BACKGROUND: The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Genomic evolution of cancer metastasis under therapeutic pressure
Abstract: In the era of precision medicine, the selection of cancer treatment relies increasingly on the identification of genomic alterations; however, it is not yet clear how frequently genomic profiling should be performed...
Concerted thermal-plus-electronic nonlocal desorption of chlorobenzene from Si(111)-7 × 7 in the STM
The rate of desorption of chemisorbed chlorobenzene molecules from the Si(111)-7 × 7 surface, induced by nonlocal charge injection from an STM tip, depends on the surface temperature. Between 260 and 313 K, we find an...
Concerted thermal-plus-electronic nonlocal desorption of chlorobenzene from Si(111)-7 × 7 in the STM
The rate of desorption of chemisorbed chlorobenzene molecules from the Si(111)-7 × 7 surface, induced by nonlocal charge injection from an STM tip, depends on the surface temperature. Between 260 and 313 K, we find an...
Neurotoxin-mediated --potent activation of the axon degeneration regulator SARM1.
Andrea Loreto, Carlo Angeletti, Weixi Gu, Andrew Osborne, Bart Nieuwenhuis, Jonathan Gilley, Peter Arthur-Farraj, Elisa Merlini, Adolfo Amici, Zhenyao Luo, Lauren Hartley-Tassell, Thomas Ve, Laura M Desrochers, Qi Wang, Bostjan Kobe, Giuseppe Orsomando, Michael P Coleman
Jan 28, 2022
Axon loss underlies symptom onset and progression in many neurodegenerative disorders. Axon degeneration in injury and disease is promoted by activation of the nicotinamide adenine dinucleotide (NAD)-consuming enzyme SARM1....
Prime-boost vaccination of mice and rhesus macaques with two novel adenovirus vectored COVID-19 vaccine candidates.
Shengxue Luo, Panli Zhang, Bochao Liu, Chan Yang, Chaolan Liang, Qi Wang, Ling Zhang, Xi Tang, Jinfeng Li, Shuiping Hou, Jinfeng Zeng, Yongshui Fu, Jean-Pierre Allain, Tingting Li, Yuming Zhang, Chengyao Li
Jun 17, 2021
ABSTRACTCOVID-19 vaccines are being developed urgently worldwide. Here, we constructed two adenovirus vectored COVID-19 vaccine candidates of Sad23L-nCoV-S and Ad49L-nCoV-S carrying the full-length gene of SARS-CoV-2 spike...
COVID-19 Vaccines human adenovirus 49 vector mice and non-human primates prime-boost vaccination simian adenovirus 23 vector Adenoviridae Animals Antibodies Neutralizing Antibodies Viral covid-19 COVID-19 Vaccines Female Genetic Vectors HEK293 Cells Humans Immunization Secondary Macaca mulatta Male Mice Mice Inbred BALB C Mice Inbred C57BL SARS-CoV-2 T-Lymphocytes
Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.
Sara Busacca, Qi Zhang, Annabel Sharkey, Alan G Dawson, David A Moore, David A Waller, Apostolos Nakas, Carolyn Jones, Kelvin Cain, Jin-Li Luo, Adriana Salcedo, Iris Chiara Salaroglio, Chiara Riganti, John Le Quesne, Tom John, Paul C Boutros, Shu-Dong Zhang, Dean A Fennell
Apr 01, 2021
We hypothesized that small molecule transcriptional perturbation could be harnessed to target a cellular dependency involving protein arginine methyltransferase 5 (PRMT5) in the context of methylthioadenosine phosphorylase...
Biomarkers Tumor Cell Transformation Neoplastic Gene Deletion Gene Expression Regulation Neoplastic Gene Silencing Humans Kaplan-Meier Estimate Mesothelioma Malignant Prognosis Protein-Arginine N-Methyltransferases Proto-Oncogene Proteins c-jun Purine-Nucleoside Phosphorylase Quinacrine Transcription Genetic
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
Dynamic Research on Youth Thought, Behavior, and Growth Law Based on Deep Learning Algorithm
Qi Fu
Apr 01, 2023
The growth and development of youth is related to the destiny of the country and the nation, and the cultivation of young people in the new era is of great significance. Youth is a special stage in life, and the ideological and...
Published by: IGI Global Scientific Publishing
A think-aloud method of investigating translanguaging strategies in learning Chinese characters
Asian scripts that are significantly different from Roman-derived alphabets usually impose difficulties in learning. Translanguaging has therefore been explored as a pedagogical tool for the language classroom, including...
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