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Results: 163
Improved Invasive Weed Optimization Algorithm for Global Maximum Power Point Tracking of PV Array Under Partial Shading Conditions
Photovoltaic (PV) array under partial shading conditions (PSCs) has several maximum power points (MPPs) on the power-voltage curve of the PV array. These points; have a unique global peak (GP) and the others are local peaks...
Published by: IGI Global Scientific Publishing
Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury.
Ali Teymoori, Anastasia Gorbunova, Fardzadeh E Haghish, Ruben Real, Marina Zeldovich, Yi-Jhen Wu, Suzanne Polinder, Thomas Asendorf, David Menon, CENTER-TBI Investigators and Participants, Nicole V Steinbüchel
Apr 30, 2020
BACKGROUND:The dimensionality of depression and anxiety instruments have recently been a source of controversy. OBJECTIVES AND DESIGN:In a European-wide sample of patients after Traumatic Brain Injury (TBI), we aim to examine...
Published by: Journal of clinical medicine
Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury
Ali Teymoori, Anastasia Gorbunova, Fardzadeh E. Haghish, Ruben Real, Marina Zeldovich, Yi-Jhen Wu, Suzanne Polinder, Thomas Asendorf, David Menon, CENTER-TBI Investigators and Participants CENTER-TBI Investigators and Participants, Nicole v. Steinbüchel
Mar 25, 2020
Background: The dimensionality of depression and anxiety instruments have recently been a source of controversy. Objectives and Design: In a European-wide sample of patients after Traumatic Brain Injury (TBI), we aim to examine...
Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury.
Ali Teymoori, Anastasia Gorbunova, Fardzadeh E Haghish, Ruben Real, Marina Zeldovich, Yi-Jhen Wu, Suzanne Polinder, Thomas Asendorf, David Menon, CENTER-TBI Investigators and Participants, Nicole V Steinbüchel
May 29, 2020
BACKGROUND: The dimensionality of depression and anxiety instruments have recently been a source of controversy. OBJECTIVES AND DESIGN: In a European-wide sample of patients after Traumatic Brain Injury (TBI), we aim to examine...
The theoretical and practical determination of clinical cut-offs for the British Sign Language versions of PHQ-9 and GAD-7.
BACKGROUND: The PHQ-9 and the GAD-7 assess depression and anxiety respectively. There are standardised, reliability-tested versions in BSL (British Sign Language) that are used with Deaf users of the IAPT service. The aim of...
What are the recovery and attrition outcomes for group CBT and individual CBT for Generalised Anxiety Disorder in an IAPT Service? An exploratory study
Group cognitive behavioural therapy (gCBT) is commonly used in Increasing Access to Psychological Therapies (IAPT) services. However, there is limited knowledge of the efficacy of gCBT as a delivery format for generalised...
What are the recovery and attrition outcomes for group CBT and individual CBT for Generalised Anxiety Disorder in an IAPT Service? An exploratory study
Group cognitive behavioural therapy (gCBT) is commonly used in Increasing Access to Psychological Therapies (IAPT) services. However, there is limited knowledge of the efficacy of gCBT as a delivery format for generalised...
Longitudinal Analyses of the Reciprocity of Depression and Anxiety after Traumatic Brain Injury and Its Clinical Implications.
Biyao Wang, Marina Zeldovich, Katrin Rauen, Yi-Jhen Wu, Amra Covic, Isabelle Muller, Juanita A Haagsma, Suzanne Polinder, David Menon, Thomas Asendorf, Nada Andelic, Nicole von Steinbuechel, CENTER-TBI Participants and Investigators
Dec 15, 2021
Depression and anxiety are common following traumatic brain injury (TBI). Understanding their prevalence and interplay within the first year after TBI with differing severities may improve patients' outcomes after TBI....
Generalised anxiety disorder and hospital admissions
Olivia Remes, Nicholas Wainwright, Paul Surtees, Louise Lafortune, Kay-Tee Khaw, Carol Brayne
Jun 12, 2018
OBJECTIVE: Generalised anxiety disorder (GAD) is the most common anxiety disorder in the general population and has been associated with high economic and human burden. However, it has been neglected in the health services...
EPIDEMIOLOGY Mental Health Public Health Adult Age Distribution Aged Anxiety Disorders Comorbidity Depressive Disorder Major Diagnostic and Statistical Manual of Mental Disorders England Female Humans Longitudinal Studies Male Middle Aged Patient Admission Prospective Studies Registries Self Report Sex Distribution
The Impact of Generalized Anxiety Disorder on Academic Performance in Undergraduate Students Following a Brief Guided Meditation
Ali Maclay
Jan 01, 0001
Many undergraduate college students report high levels of anxiety, which can negatively impact their academic performance. Meditation is currently being explored as a method to reduce anxiety, with the duration and frequency...
Meditation and Test Anxiety Test Performance Guided Meditation Community Psychology Mental Disorders Psychology
Published by: Winthrop University
Comparative effectiveness of cognitive therapies delivered face-to-face or over the telephone
Geoffrey C Hammond, Tim J Croudace, Muralikrishnan Radhakrishnan, Louise Lafortune, Alison Watson, Fiona McMillan-Shields, Peter B Jones
Aug 05, 2020
OBJECTIVES: To compare the clinical and cost-effectiveness of face-to-face (FTF) with over-the-telephone (OTT) delivery of low intensity cognitive behavioural therapy. DESIGN: Observational study following SROBE guidelines....
How does music performance anxiety relate to other anxiety disorders?
Music performance anxiety (MPA) is considered a social anxiety disorder
(SAD). Recent conceptualisations, however, challenge existing MPA
definitions, distinguishing MPA from SAD. In this study, we aim to
provide a systematic...
Towards clinical utility of polygenic risk scores.
Prediction of disease risk is an essential part of preventative medicine, often guiding clinical management. Risk prediction typically includes risk factors such as age, sex, family history of disease and lifestyle (e.g. smoking...
Alzheimer Disease Breast Neoplasms Coronary Artery Disease Diabetes mellitus Type 1 Diabetes mellitus Type 2 Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Medical History Taking Multifactorial Inheritance obesity Prostatic Neoplasms Reproducibility of Results Risk Factors
Interactions between callose and cellulose revealed through the analysis of biopolymer mixtures.
Radwa H Abou-Saleh, Mercedes C Hernandez-Gomez, Sam Amsbury, Candelas Paniagua, Matthieu Bourdon, Shunsuke Miyashima, Ykä Helariutta, Martin Fuller, Tatiana Budtova, Simon D Connell, Michael E Ries, Yoselin Benitez-Alfonso
Dec 18, 2018
The properties of (1,3)-β-glucans (i.e., callose) remain largely unknown despite their importance in plant development and defence. Here we use mixtures of (1,3)-β-glucan and cellulose, in ionic liquid solution and hydrogels, as...
Usefulness of self-report questionnaires for psychological assessment of patients with tinnitus and hyperacusis and patients’ views of the questionnaires
OBJECTIVE: The objective was to determine the relevance and applicability of psychological questionnaires to patients seeking help for tinnitus and/or hyperacusis. DESIGN: This was a questionnaire-based survey. The following...
Comparison of Salmonella enterica Serovars Typhi and Typhimurium Reveals Typhoidal Serovar-Specific Responses to Bile.
Rebecca Johnson, Matt Ravenhall, Derek Pickard, Gordon Dougan, Alexander Byrne, Gad Frankel
Jun 25, 2018
Salmonella enterica serovars Typhi and Typhimurium cause typhoid fever and gastroenteritis, respectively. A unique feature of typhoid infection is asymptomatic carriage within the gallbladder, which is linked with S Typhi...
Very long O-antigen chains of Salmonella Paratyphi A inhibit inflammasome activation and pyroptotic cell death.
Elli Mylona, Julia Sanchez-Garrido, Trang Nguyen Hoang Thu, Sabina Dongol, Abhilasha Karkey, Stephen Baker, Avinash R Shenoy, Gad Frankel
Jan 22, 2021
Salmonella Paratyphi A (SPtA) remains one of the leading causes of enteric (typhoid) fever. Yet, despite the recent increased rate of isolation from patients in Asia, our understanding of its pathogenesis is incomplete. Here we...
FepE O-antigen Salmonella paratyphi A Salmonella typhimurium caspase-4 enteric fever Inflammasomes pyroptosis Bacterial Proteins Caspases HeLa Cells Humans Inflammasomes Intracellular Signaling Peptides and Proteins MACROPHAGES O Antigens Paratyphoid Fever Phosphate-Binding Proteins pyroptosis Salmonella paratyphi A THP-1 Cells Type III Secretion Systems Virulence Virulence Factors
Accurate and robust genomic prediction of celiac disease using statistical learning.
Gad Abraham, Jason A Tye-Din, Oneil G Bhalala, Adam Kowalczyk, Justin Zobel, Michael Inouye
Nov 08, 2018
Practical application of genomic-based risk stratification to clinical diagnosis is appealing yet performance varies widely depending on the disease and genomic risk score (GRS) method. Celiac disease (CD), a common...
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
Gad Abraham, Rainer Malik, Ekaterina Yonova-Doing, Agus Salim, Tingting Wang, John Danesh, Adam S Butterworth, Joanna M M Howson, Michael Inouye, Martin Dichgans
Jan 27, 2020
Recent genome-wide association studies in stroke have enabled the generation of genomic risk scores (GRS) but their predictive power has been modest compared to established stroke risk factors. Here, using a meta-scoring...
Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
Siddhartha P Kar, Hermann Brenner, Graham G Giles, Dezheng Huo, Roger L Milne, Gad Rennert, Jacques Simard, Wei Zheng, Stephen Burgess, Paul DP Pharoah
Apr 15, 2019
The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation.
Samuel A Lambert, Laurent Gil, Simon Jupp, Scott C Ritchie, Yu Xu, Annalisa Buniello, Aoife McMahon, Gad Abraham, Michael Chapman, Helen Parkinson, John Danesh, Jacqueline AL MacArthur, Michael Inouye
Nov 09, 2020
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P Lolkema, Neeltje Steeghs, Gad Getz, Quaid D Morris, Lincoln D Stein, PCAWG Consortium
May 14, 2020
In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of...
Genomic risk scores for juvenile idiopathic arthritis and its subtypes
Rodrigo Cánovas, Joanna Cobb, Marta Brozynska, John Bowes, Yun R Li, Samantha Louise Smith, Hakon Hakonarson, Wendy Thomson, Justine A Ellis, Gad Abraham, Jane E Munro, Michael Inouye
Sep 09, 2020
Objectives: Juvenile idiopathic arthritis (JIA) is an autoimmune disease and a common cause of chronic disability in children. Diagnosis of JIA is based purely on clinical symptoms, which can be variable, leading to diagnosis...
Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality.
Scott C Ritchie, Johannes Kettunen, Marta Brozynska, Artika P Nath, Aki S Havulinna, Satu Männistö, Markus Perola, Veikko Salomaa, Mika Ala-Korpela, Gad Abraham, Peter Würtz, Michael Inouye
Feb 07, 2020
BACKGROUND: GlycA is a nuclear magnetic resonance (NMR) spectroscopy biomarker that predicts risk of disease from myriad causes. It is heterogeneous; arising from five circulating glycoproteins with dynamic concentrations...
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