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A Study of Prevalence of Intestinal Helminthic Infections and Associated Risk Factors among the Tea Estates workers of Ilam District, Eastern Region of Nepal
Introduction: Intestinal parasites are widely prevalent in developing countries, probably due to poor sanitation and inadequate personal hygiene. It is estimated that as much as 60% of the world’s population is infected with...
Published by: IJHS Medical Association
A Study of Prevalence of Intestinal Helminthic Infections and Associated Risk Factors among the Tea Estates workers of Ilam District, Eastern Region of Nepal
Introduction: Intestinal parasites are widely prevalent in developing countries, probably due to poor sanitation and inadequate personal hygiene. It is estimated that as much as 60% of the world’s population is infected with...
Published by: IJHS Medical Association
Aberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilization.
Anaplastic Lymphoma Kinase (ALK) is a receptor tyrosine kinase aberrantly expressed in a variety of tumor types, most notably in Anaplastic Large Cell Lymphoma (ALCL) where a chromosomal translocation generates the oncogenic...
Anaplastic Lymphoma Kinase Animals Cell Adhesion Cell Cycle Cell Proliferation Cell Transformation Neoplastic Cells Cultured Cellular Senescence Cyclin-Dependent Kinase Inhibitor p16 Embryo Mammalian FIBROBLASTS Humans Mice Models Biological Mutation Protein Processing Post-Translational Protein Stability Protein-Tyrosine Kinases Receptor Protein-Tyrosine Kinases Retinoblastoma Protein Transcription Genetic Tumor Suppressor Protein p53
Recruitment of Antigen Presenting Cells to Skin Draining Lymph Node From HPV16E7-Expressing Skin Requires E7-Rb Interaction.
Paula Kuo, Siok Min Teoh, Zewen K Tuong, Graham R Leggatt, Stephen R Mattarollo, Ian H Frazer
Aug 20, 2021
"High-risk" human papillomaviruses (HPV) infect keratinocytes of squamous epithelia. The HPV16E7 protein induces epithelial hyperplasia by binding Rb family proteins and disrupting cell cycle termination. Murine skin expressing...
APC CIN HPV16 Keratinocytes Retinoblastoma Protein skin grafting Animals Antigen-Presenting Cells Disease Models Animal epidermis Female Human papillomavirus 16 Humans Hyperplasia Keratinocytes Lymph Nodes Mice Mice Inbred C57BL Mice Transgenic Papillomavirus E7 Proteins Papillomavirus Infections Protein Binding Retinoblastoma Binding Proteins Retinoblastoma Protein
Recumbent vs. upright bicycles
Recumbent bicycles (RB) are high performance, human-powered vehicles. In comparison to normal/upright bicycles (NB) the RB may allow individuals to reach higher speeds due to aerodynamic advantages. The purpose of this...
Regulated Recruitment of the Chromosomal Passenger Complex to Chromatin and Microtubules Promotes Accurate Cell Division
Michael Wheelock
Jan 01, 0001
Aurora B, the kinase subunit of the chromosomal passenger complex (CPC), promotes accurate cell division by destabilizing erroneous kinetochoremicrotubule attachments and activating the spindle assembly checkpoint (SAC). Both...
Published by: Rockefeller University
Subarachnoid hemorrhage in rats - Visualizing blood distribution in vivo using gadolinium-enhanced magnetic resonance imaging
Elisabeth Simader, Lubos Budinsky, Thomas H Helbich, Camillo Sherif, Romana Höftberger, Gregor Kasprian, Thomas Raunegger, Philipp Hacker, Hendrik Jan Ankersmit, Lucian Beer, Thomas Haider
Sep 25, 2019
BACKGROUND: The aims of this study were to assess the feasibility of magnetic resonance imaging (MRI) to track the in vivo distribution of autologous, injected blood in a subarachnoid hemorrhage model (SAH), and to evaluate...
Cultural Differences in Digital Game Experiences
The literature proposes that East Asians have a holistic view focusing on both salient objects and their backgrounds, whereas Westerners maintain an analytic view paying attention to focal objects and their attributes. Moreover...
Published by: IGI Global Scientific Publishing
Baroreflex Impairment After Subarachnoid Hemorrhage Is Associated With Unfavorable Outcome.
Nathalie Nasr, Rita Gaio, Marek Czosnyka, Karol Budohoski, Xiuyun Liu, Joseph Donnelly, Marek Sykora, Peter Kirkpatrick, Anne Pavy-Le Traon, Christina Haubrich, Vincent Larrue, Peter Smielewski
Oct 10, 2018
BACKGROUND AND PURPOSE: Aneurysmal subarachnoid hemorrhage (SAH) is characterized by important changes in the autonomic nervous system with potentially adverse consequences. The baroreflex has a key role in regulating the...
Recumbent vs. upright bicycles
Recumbent bicycles (RB) are high performance, human-powered vehicles. In comparison to normal/upright bicycles (NB) the RB may allow individuals to reach higher speeds due to aerodynamic advantages. The purpose of this...
Association of p53 rs1042522, MDM2 rs2279744, and p21 rs1801270 polymorphisms with retinoblastoma risk and invasion in a Chinese population.
Rongxin Chen, Shu Liu, Huijing Ye, Jiali Li, Yi Du, Lingyan Chen, Xiaoman Liu, Yungang Ding, Qian Li, Yuxiang Mao, Siming Ai, Ping Zhang, Wenfang Ma, Huasheng Yang
Nov 13, 2018
Single nucleotide polymorphisms (SNPs) of p53 rs1042522, MDM2 rs2279744 and p21 rs1801270, all in the p53 pathway, which plays a crucial role in DNA damage and genomic instability, were reported to be associated with cancer risk...
Adult Asian People China Cyclin-Dependent Kinase Inhibitor p21 Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Humans Kaplan-Meier Estimate Male Polymorphism Single Nucleotide Proportional Hazards Models Proto-Oncogene Proteins c-mdm2 retinoblastoma Risk Factors Tumor Suppressor Protein p53
DREAM represses distinct targets by cooperating with different THAP domain proteins.
Csenge Gal, Francesco Nicola Carelli, Alex Appert, Chiara Cerrato, Ni Huang, Yan Dong, Jane Murphy, Andrea Frapporti, Julie Ahringer
Sep 27, 2021
The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear. Here, we demonstrate that two...
dream H2A.Z H3K9me2 THAP lin-15B lin-35 lin-36 quiescence retinoblastoma TRANSCRIPTIONAL REPRESSION Animals Animals Genetically Modified Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Proteins DNA Methylation E2F Transcription Factors Gene Expression Regulation Histones Promoter Regions Genetic Protein Binding Protein Interaction Domains and Motifs Retinoblastoma Protein Transcription Factors
Rubidium and caesium aluminyls
Thomas Gentner, Matt Evans, Alan Kennedy, Sam Neale, Claire McMullin, Martyn Coles, Robert Mulvey
Jan 28, 2022
Expanding knowledge of low valent aluminium chemistry, rubidium and caesium aluminyls are reported to complete the group 1 (Li–Cs) set of metal aluminyls. Both compounds crystallize as a contacted dimeric pair supported by...
Rubidium and caesium aluminyls
Thomas Gentner, Matt Evans, Alan Kennedy, Sam Neale, Claire McMullin, Martyn Coles, Robert Mulvey
Jan 28, 2022
Expanding knowledge of low valent aluminium chemistry, rubidium and caesium aluminyls are reported to complete the group 1 (Li–Cs) set of metal aluminyls. Both compounds crystallize as a contacted dimeric pair supported by...
An Ensemble Approach for Prediction of Cardiovascular Disease Using Meta Classifier Boosting Algorithms
There are very few studies are carried for investigating the potential of hybrid ensemble machine learning techniques for building a model for the detection and prediction of heart disease in the human body. In this research...
Published by: IGI Global Scientific Publishing
Air Pollution and Migration
This paper investigates the impact of air pollution on China’s internal migration using the Migrant Population Dynamic Monitoring Survey and Air Quality Index (AQI) data in 2014. Binary response models suggest that, on average...
Published by: IGI Global Scientific Publishing
Applying Citizen Science for Sustainable Development
We introduce a case-study agnostic framework for the application of citizen science in a sustainable development context. This framework is tested against an activity in two secondary schools in western Nepal. While the...
Monitoring the Neuroinflammatory Response Following Acute Brain injury
EP Thelin, T Tajsic, FA Zeiler, DK Menon, PJA Hutchinson, KLH Carpenter, MC Morganti-Kossmann, A Helmy
Jul 25, 2017
Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are major contributors to morbidity and mortality. Following the initial insult, patients may deteriorate due to secondary brain damage. The underlying molecular and...
Subarachnoid haemorrhage with negative initial neurovascular imaging
Midhun Mohan, Abdurrahman I Islim, Fahid T Rasul, Ola Rominiyi, Ruth-Mary deSouza, Michael TC Poon, Aimun AB Jamjoom, Angelos G Kolias, Julie Woodfield, Krunal Patel, Aswin Chari, Ramez Kirollos, British Neurosurgical Trainee Research Collaborative
Oct 22, 2019
BACKGROUND: In patients with spontaneous subarachnoid haemorrhage (SAH), a vascular cause for the bleed is not always found on initial investigations. This study aimed to systematically evaluate the delayed investigation...
Modeling Inner Proton Belt Variability at Energies 1 to 10 MeV Using BAS-PRO
Abstract: Geomagnetically trapped protons forming Earth's proton radiation belt pose a hazard to orbiting spacecraft. In particular, solar cell degradation is caused by non‐ionising collisions with protons at energies of several...
Subarachnoid haemorrhage with negative initial neurovascular imaging
Midhun Mohan, Abdurrahman I. Islim, Fahid T. Rasul, Ola Rominiyi, Ruth-Mary deSouza, Michael T. C. Poon, Aimun A. B. Jamjoom, Angelos G. Kolias, Julie Woodfield, Krunal Patel, Aswin Chari, Ramez Kirollos
Aug 12, 2020
Abstract: Background: In patients with spontaneous subarachnoid haemorrhage (SAH), a vascular cause for the bleed is not always found on initial investigations. This study aimed to systematically evaluate the delayed...
Synergistic effects of combining ultrasound with the Fenton process in the degradation of Reactive Blue 19
The decoloration of reactive dye C.I. Reactive Blue 19 (RB 19) using combined ultrasound with the Fenton process has been investigated. The effect of varying the concentrations of hydrogen peroxide and iron sulfate, initial...
Synergistic effects of combining ultrasound with the Fenton process in the degradation of Reactive Blue 19
The decoloration of reactive dye C.I. Reactive Blue 19 (RB 19) using combined ultrasound with the Fenton process has been investigated. The effect of varying the concentrations of hydrogen peroxide and iron sulfate, initial...
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