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Results: 1315
Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy.
Shi Cheng, Marcel M van Gaalen, Mathias Bähr, Enrique Garea-Rodriguez, Sebastian Kügler
Oct 26, 2021
Gene therapy in its current design is an irreversible process. It cannot be stopped in case of unwanted side effects, nor can expression levels of therapeutics be adjusted to individual patient's needs. Thus, the Gene-Switch...
Nonlinear mixed-effects scalar-on-function models and variable selection
Abstract: This paper is motivated by our collaborative research and the aim is to model clinical assessments of upper limb function after stroke using 3D-position and 4D-orientation movement data. We present a new nonlinear...
A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells
Quan Jiang, Xiao-Rong Li, Cheng-Kun Wang, Juan Cheng, Chao Tan, Tian-Tian Cui, Nan-Nan Lu, Tony D James, Feng Han, Xin Li
Feb 21, 2018
This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has...
/dk/atira/pure/subjectarea/asjc/1500/1503 name=Catalysis /dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2500/2503 name=Ceramics and Composites /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/2500/2506 name=Metals and Alloys /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics.
Suwei Gao, Qiang Shi, Yifan Zhang, Guixian Liang, Zhixin Kang, Baofeng Huang, Dongyuan Ma, Lu Wang, Jianwei Jiao, Xiangdong Fang, Cheng-Ran Xu, Longqi Liu, Xun Xu, Berthold Göttgens, Cheng Li, Feng Liu
Jul 14, 2021
A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells
Quan Jiang, Xiao-Rong Li, Cheng-Kun Wang, Juan Cheng, Chao Tan, Tian-Tian Cui, Nan-Nan Lu, Tony D James, Feng Han, Xin Li
Feb 21, 2018
This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has...
/dk/atira/pure/subjectarea/asjc/1500/1503 name=Catalysis /dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2500/2503 name=Ceramics and Composites /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/2500/2506 name=Metals and Alloys /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue
Lauren V. C. Miller, Aamir S. Mukadam, Claire S. Durrant, Marina J. Vaysburd, Taxiarchis Katsinelos, Benjamin J. Tuck, Sophie Sanford, Olivia Sheppard, Claire Knox, Shi Cheng, Leo C. James, Michael P. Coleman, William A. McEwan
Mar 12, 2021
A Novel Approach to Distributed Rule Matching and Multiple Firing Based on MapReduce
In order to solve the poor performance problem of massive rules reasoning, as well as the inconsistency problem of working memory in distributed rule matching, this article presents the formal definition of interference...
Published by: IGI Global Scientific Publishing
Screening for Obstructive Sleep Apnea Risk by Using Machine Learning Approaches and Anthropometric Features.
Cheng-Yu Tsai, Huei-Tyng Huang, Hsueh-Chien Cheng, Jieni Wang, Ping-Jung Duh, Wen-Hua Hsu, Marc Stettler, Yi-Chun Kuan, Yin-Tzu Lin, Chia-Rung Hsu, Kang-Yun Lee, Jiunn-Horng Kang, Dean Wu, Hsin-Chien Lee, Cheng-Jung Wu, Arnab Majumdar, Wen-Te Liu
Jan 04, 2023
Obstructive sleep apnea (OSA) is a global health concern and is typically diagnosed using in-laboratory polysomnography (PSG). However, PSG is highly time-consuming and labor-intensive. We, therefore, developed machine learning...
Assurance of Network Communication Information Security Based on Cyber-Physical Fusion and Deep Learning
The internet brings high efficiency and convenience to society; however, the issue of information security in network communication has significantly affected every aspect of the society. How to ensure the security of this...
Published by: IGI Global Scientific Publishing
Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue.
Lauren VC Miller, Aamir S Mukadam, Claire S Durrant, Marina J Vaysburd, Taxiarchis Katsinelos, Benjamin J Tuck, Sophie Sanford, Olivia Sheppard, Claire Knox, Shi Cheng, Leo C James, Michael P Coleman, William A McEwan
Feb 24, 2021
neurodegeneration Organotypic hippocampal slice cultures Prion-like activity Tau seeded aggregation Tauopathies Alzheimer Disease Animals Disease Models Animal HEK293 Cells Hippocampus Humans In Vitro Techniques Mice Mice Transgenic Phosphorylation Prions protein aggregation Pathological Tauopathies Tissue Culture Techniques tau Proteins
Applying the core-satellite species concept
Masumi Stadler, Malcolm A Barnard, Kadir Bice, Michaela L de Melo, Dipankar Dwivedi, Erika C Freeman, Vanessa A Garayburu-Caruso, Annika Linkhorst, Erick Mateus-Barros, Cheng Shi, Andrew J Tanentzap, Christof Meile
Apr 13, 2023
Damage resistance and damage tolerance of hybrid carbon-glass laminates
The influence of impact energy and stacking sequence on the damage resistance and Compression After Impact (CAI) strength of Carbon and Glass Fibre Reinforced Plastic (CFRP and GFRP respectively) hybrid laminates is...
Screening for Obstructive Sleep Apnea Risk by Using Machine Learning Approaches and Anthropometric Features.
Cheng-Yu Tsai, Huei-Tyng Huang, Hsueh-Chien Cheng, Jieni Wang, Ping-Jung Duh, Wen-Hua Hsu, Marc Stettler, Yi-Chun Kuan, Yin-Tzu Lin, Chia-Rung Hsu, Kang-Yun Lee, Jiunn-Horng Kang, Dean Wu, Hsin-Chien Lee, Cheng-Jung Wu, Arnab Majumdar, Wen-Te Liu
Dec 08, 2022
Grammatical Relations, Transitivity and Ergativity
Cheng Luo
Sep 05, 2013
Keenan and Comrie's Accessibility Hierarchy (AH) applied to clefting predicts greater c1eftability of subject (s U) than direct object (DO). However, in some Eastern Austronesian languages, particularly Tongan, some transitive...
Published by: Atlantic Provinces Linguistic Association
Damage resistance and damage tolerance of hybrid carbon-glass laminates
The influence of impact energy and stacking sequence on the damage resistance and Compression After Impact (CAI) strength of Carbon and Glass Fibre Reinforced Plastic (CFRP and GFRP respectively) hybrid laminates is...
A Secure and Fast Range Query Scheme for Encrypted Multi-Dimensional Data
Zhuolin Mei, Jinzhou Huang, Bin Wu, Caicai Zhang, Huilai Zou, Jiaoli Shi, Zhengxiang Cheng
Jan 01, 2024
In recent years, more and more data has been stored on the cloud to provide various services. These data often contain users' private information, which inevitably raises concerns about data security. Encryption before...
Published by: IGI Global Scientific Publishing
Typological Parameters for the Lexica-syntactic Structures of High-digit Numerical Expressions
Cheng Luo
Jul 30, 2013
The objective of this paper is to explore the lexico-syntactic structure of high-digit numerical expressions (henceforth HDNEs), normally with 4 digits and more, and to propose a set of typological parameters to account for...
Published by: Atlantic Provinces Linguistic Association
Building an Allocentric Traveling-Direction Signal Via Vector Computation
Cheng Lyu
Jan 01, 0001
Many behavioral tasks require the manipulation of mathematical vectors, but, outside of computational models, it is not known how brains perform vector operations. Here we show how the Drosophila central complex, a region...
Published by: Rockefeller University
Grammatical Relations, Transitivity and Ergativity
Cheng Luo
Sep 05, 2013
Keenan and Comrie's Accessibility Hierarchy (AH) applied to clefting predicts greater c1eftability of subject (s U) than direct object (DO). However, in some Eastern Austronesian languages, particularly Tongan, some transitive...
Published by: Atlantic Provinces Linguistic Association
Selective Dealkenylative Functionalization of Styrenes via C-C Bond Cleavage.
As a readily available feedstock, styrene with about 25 million tons of global annual production serves as an important building block and organic synthon for the synthesis of fine chemicals, polystyrene plastics, and...
Airborne Molecular Contamination
This review paper focuses on the recent knowledge about airborne molecular contamination (AMC) and its impacts on 300-mm wafer fabrication processes. The adverse impacts on process materials by both organic and inorganic...
Published by: Digital Commons @ Texas A&M University-San Antonio
Photorealistic Audio-driven Video Portraits
Video portraits are common in a variety of applications, such as videoconferencing, news broadcasting, and virtual education and training. We present a novel method to synthesize photorealistic video portraits for an input...
Confining Nanopore Bipolar Electrochemical Processes to Give Pattern in Space and Time
Frank Marken
Sep 01, 2017
"Wireless" metal-coated nanopore electrode processes have been developed by Long and co-workers (R. Gao, Y. Lin, Y.-L. Ying, X.-Y. Liu, X. Shi, Y.-X. Hu, Y.-T. Long, Small, 2017 DOI: 10.1002/smll.201700234), confining bipolar...
Do You Speak Chinese, Mandarin, or Cantonese? An Explanation Based on a Native Chinese Speaker’s Early Experience
Cheng Li
Dec 20, 2018
This article reports on my early experiences with learning and speaking varieties of Chinese, responding to the curious questions on the power relationship between Mandarin and other dialects in China today. A series of...
Published by: The Morning Watch: Educational and Social Analysis
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