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Analysis and Outcome Prediction of Crowdfunding Campaigns
Humongous volumes of data are being generated every minute by individual users as well as organizations. This data can be turned into a valuable asset only if it is analyzed, interpreted and used for improving processes or for...
Published by: IGI Global Scientific Publishing
Antecedents of Organizational Agility During Business Uncertainty in Noninformation Technology Sectors
Dinesh Batra
Jan 01, 2022
The prolonged COVID-19 pandemic, economic stress, and geopolitical tensions have caused market disruptions and other forces that have likely increased organizational agility. This article focuses on the antecedents of...
Published by: IGI Global Scientific Publishing
A multisource energy harvesting utilizing highly efficient ferroelectric PMN-PT single crystal
This paper demonstrates a multi-source energy harvester that is able to utilize simultaneously both piezoelectric and pyroelectric effects in lead magnesium niobate-lead titanate (PMN-PT) single crystal. The paper presents a...
A multisource energy harvesting utilizing highly efficient ferroelectric PMN-PT single crystal
This paper demonstrates a multi-source energy harvester that is able to utilize simultaneously both piezoelectric and pyroelectric effects in lead magnesium niobate-lead titanate (PMN-PT) single crystal. The paper presents a...
A versatile and fully instrumented test station for piezoelectric energy harvesters
This paper describes the implementation of LabVIEW software to control instruments and acquire data from a piezoelectric energy harvesting test station which is based on a cantilever structure. The experiment is run in the...
A versatile and fully instrumented test station for piezoelectric energy harvesters
This paper describes the implementation of LabVIEW software to control instruments and acquire data from a piezoelectric energy harvesting test station which is based on a cantilever structure. The experiment is run in the...
On the mechanisms of DC conduction in electrospun PLZT/PVDF nanocomposite membranes
James C. Sampson, Ashok Batra, Matthew E. Edwards, Sushma Kotru, Chris R. Bowen, Ashok Vaseashta
Feb 28, 2022
Designing dielectric nanocomposite films with excellent dielectric properties is of strategic importance for a variety of applications requiring pressure sensing, energy harvesting and storing, and biomedical technology....
Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts.
Maurizio Callari, Ankita Sati Batra, Rajbir Nath Batra, Stephen Sammut, Wendy Greenwood, Harry Clifford, Colin Hercus, Suet-Feung Chin, Alejandra Bruna, Oscar M Rueda, Carlos Caldas
Mar 08, 2018
Background - Patient-Derived Tumour Xenografts (PDTXs) have emerged as the pre-clinical models that best represent clinical tumour diversity and intra-tumour heterogeneity. The molecular characterization of PDTXs using...
On the mechanisms of DC conduction in electrospun PLZT/PVDF nanocomposite membranes
James C. Sampson, Ashok Batra, Matthew E. Edwards, Sushma Kotru, Chris R. Bowen, Ashok Vaseashta
Feb 28, 2022
Designing dielectric nanocomposite films with excellent dielectric properties is of strategic importance for a variety of applications requiring pressure sensing, energy harvesting and storing, and biomedical technology....
Psychological Correlates of Perfectionistic Self-Presentation Among Social Media Users
The recent burgeon on social media usage has contributed to much research examining the role of enmeshing psychological and psychosocial factors. Concerning the existing scenario, this study investigates the networking between...
Published by: IGI Global Scientific Publishing
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis- regulation
Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H. Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian Ellis, Andrew Green, Francine E. Garrett-Bakelman, Chris Mason, Ari Melnick, Samuel A. J. R. Aparicio, Oscar M. Rueda, Amos Tanay, Carlos Caldas
Sep 13, 2021
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation.
Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian Ellis, Andrew Green, Francine E Garrett-Bakelman, Chris Mason, Ari Melnick, Samuel A J R Aparicio, Oscar M Rueda, Amos Tanay, Carlos Caldas
Oct 18, 2021
Published by: Nature Communications
Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome.
Ana Tufegdzic Vidakovic, Oscar M Rueda, Stephin J Vervoort, Ankita Sati Batra, Mae Akilina Goldgraben, Santiago Uribe-Lewis, Wendy Greenwood, Paul J Coffer, Alejandra Bruna, Carlos Caldas
Oct 21, 2015
Binding Sites Cell Line Tumor DNA DNA Methylation Epigenesis Genetic Histones Humans Neoplastic Stem Cells Promoter Regions Genetic Protein Binding RNA Interference RNA Small Interfering Signal Transduction Smad2 Protein Smad3 Protein Trans-Activators Transcription Factors Transforming Growth Factor beta
MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.
Zheng Xue, Daniel J Vis, Alejandra Bruna, Tonci Sustic, Sake van Wageningen, Ankita Sati Batra, Oscar M Rueda, Evert Bosdriesz, Carlos Caldas, Lodewyk FA Wessels, René Bernards
Apr 29, 2019
Activation of the mitogen-activated protein kinase (MAPK) pathway is frequent in cancer. Drug development efforts have been focused on kinases in this pathway, most notably on RAF and MEK. We show here that MEK inhibition...
Animals Benzimidazoles Breast Neoplasms Cell Line Tumor Colonic Neoplasms Drug Resistance Neoplasm Female Heterografts Humans Loss of Function Mutation MAP Kinase Kinase 4 MAP Kinase Kinase Kinase 1 MAP Kinase Signaling System Male Mice Inbred BALB C Mice Nude Mitogen-Activated Protein Kinase Kinases Prostatic Neoplasms Protein Kinase Inhibitors
A Meta-Analytical Review of Antecedents of Organizational Ambidexterity
The aim of the study is to conduct a structured review of literature on the antecedents of organizational ambidexterity by reconciling the mixed outcomes produced by the extant literature. This study offers some theoretical...
Published by: IGI Global Scientific Publishing
A Systematic Review of Tools Available in the Field of Augmented Reality
Augmented Reality interfaces have been extensively researched throughout the past few decades, with many user studies being conducted. This paper examines the landscape of research on augmented reality. We summarise the overall...
Published by: IGI Global Scientific Publishing
The hereditary predisposition to hip osteoarthritis and its association with abnormal joint morphology
T C B Pollard, R N Batra, A Judge, B Watkins, E G McNally, H S Gill, G E R Thomas, S Glyn-Jones, N K Arden, A J Carr
Feb 01, 2013
Objective:
Genetic factors and abnormalities of joint morphology are important in the aetiology of hip osteoarthritis (OA). The extent to which genetic influences are manifest through joint morphology has undergone limited...
Genetic factors and abnormalities of joint morphology are important in the aetiology of hip osteoarthritis (OA). The extent to which genetic influences are manifest through joint morphology has undergone limited...
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation.
Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian Ellis, Andrew Green, Francine E Garrett-Bakelman, Chris Mason, Ari Melnick, Samuel AJR Aparicio, Oscar M Rueda, Amos Tanay, Carlos Caldas
Nov 05, 2021
DNA methylation is aberrant in cancer, but the dynamics, regulatory role and clinical implications of such epigenetic changes are still poorly understood. Here, reduced representation bisulfite sequencing (RRBS) profiles of 1538...
Assessing the efficiency of countries in making progress towards universal health coverage
Emma Jordi, Caitlin Pley, Matthew Jowett, Gerard Joseph Abou Jaoude, Hassan Haghparast-Bidgoli
Nov 02, 2020
INTRODUCTION: Maximising efficiency of resources is critical to progressing towards universal health coverage (UHC) and the sustainable development goal (SDG) for health. This study estimates the technical efficiency of national...
A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival.
The hereditary predisposition to hip osteoarthritis and its association with abnormal joint morphology
T C B Pollard, R N Batra, A Judge, B Watkins, E G McNally, H S Gill, G E R Thomas, S Glyn-Jones, N K Arden, A J Carr
Feb 01, 2013
Objective:
Genetic factors and abnormalities of joint morphology are important in the aetiology of hip osteoarthritis (OA). The extent to which genetic influences are manifest through joint morphology has undergone limited...
Genetic factors and abnormalities of joint morphology are important in the aetiology of hip osteoarthritis (OA). The extent to which genetic influences are manifest through joint morphology has undergone limited...
A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.
Alejandra Bruna, Oscar M Rueda, Wendy Greenwood, Ankita Sati Batra, Maurizio Callari, Rajbir Nath Batra, Katherine Pogrebniak, Jose Sandoval, John W Cassidy, Ana Tufegdzic-Vidakovic, Stephen-John Sammut, Linda Jones, Elena Provenzano, Richard Baird, Peter Eirew, James Hadfield, Matthew Eldridge, Anne McLaren-Douglas, Andrew Barthorpe, Howard Lightfoot, Mark J O'Connor, Joe Gray, Javier Cortes, Jose Baselga, Elisabetta Marangoni, Alana L Welm, Samuel Aparicio, Violeta Serra, Mathew J Garnett, Carlos Caldas
Oct 21, 2016
Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.
Oscar M Rueda, Stephen-John Sammut, Jose A Seoane, Suet-Feung Chin, Jennifer L Caswell-Jin, Maurizio Callari, Rajbir Batra, Bernard Pereira, Alejandra Bruna, H Raza Ali, Elena Provenzano, Bin Liu, Michelle Parisien, Cheryl Gillett, Steven McKinney, Andrew R Green, Leigh Murphy, Arnie Purushotham, Ian O Ellis, Paul D Pharoah, Cristina Rueda, Samuel Aparicio, Carlos Caldas, Christina Curtis
Feb 21, 2019
Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.
Eliana MC Tacconi, Sophie Badie, Giuliana De Gregoriis, Timo Reisländer, Xianning Lai, Manuela Porru, Cecilia Folio, John Moore, Arnaud Kopp, Júlia Baguña Torres, Deborah Sneddon, Marcus Green, Simon Dedic, Jonathan W Lee, Ankita Sati Batra, Oscar M Rueda, Alejandra Bruna, Carlo Leonetti, Carlos Caldas, Bart Cornelissen, Laurent Brino, Anderson Ryan, Annamaria Biroccio, Madalena Tarsounas
Jul 31, 2019
BRCA1 BRCA2 DNA damage responses alkylating agents cisplatin Animals BRCA1 Protein BRCA2 Protein Cell Line Tumor Chlorambucil Cricetinae Drug Delivery Systems Drug Resistance Neoplasm Humans Leukemia Lymphocytic Chronic B-Cell Male Mice Mice SCID Peroxisome Proliferator-Activated Receptors Phthalazines Piperazines Xenograft Model Antitumor Assays
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