Search
Results: 510
Framework for Smart City Model Composition
This paper is a reflective overview of the knowledge on online conversion of services in the perspective of urban planning. It points that traditional planning aimed at building optimal spatial relationships between particular...
Published by: IGI Global Scientific Publishing
A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2.
Man-Hong Leung, Ho Tsoi, Chun Gong, Ellen PS Man, Stefania Zona, Shang Yao, Eric W-F Lam, Ui-Soon Khoo
Feb 27, 2020
Breast cancer is the most common type of female cancer. Reactive oxygen species (ROS) are vital in regulating signaling pathways that control cell survival and cell proliferation. Chemotherapeutic drugs such as anthracyclines...
Repurposing hyperpolarization-activated cyclic nucleotide-gated channels as a novel therapy for breast cancer.
Ka-Chun Mok, Ho Tsoi, Ellen PS Man, Man-Hong Leung, Ka Man Chau, Lai-San Wong, Wing-Lok Chan, Sum-Yin Chan, Mai-Yee Luk, Jessie YW Chan, Jackie KM Leung, Yolanda HY Chan, Sellma Batalha, Virginia Lau, David CW Siu, Terence KW Lee, Chun Gong, Ui-Soon Khoo
Nov 04, 2021
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are members of the voltage-gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN...
BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen-Resistant Breast Cancer.
Chun Gong, Ellen PS Man, Ho Tsoi, Terence KW Lee, Paul Lee, Sai-Ting Ma, Lai-San Wong, Mai-Yee Luk, Emad A Rakha, Andrew R Green, Ian O Ellis, Eric W-F Lam, Kwok-Leung Cheung, Ui-Soon Khoo
Jan 08, 2019
Purpose: Adjuvant tamoxifen treatment revolutionized the management of estrogen receptor (ER)-positive breast cancers to prevent cancer recurrence; however, drug resistance compromises its clinical efficacy. The mechanisms...
Adult Aged Animals Antineoplastic Agents Hormonal Breast Neoplasms Chemotherapy Adjuvant Drug Resistance Neoplasm Female Gene Expression Regulation Neoplastic Humans Immunohistochemistry MCF-7 Cells Mice Middle Aged Neoplasm Recurrence Local Nuclear Receptor Co-Repressor 2 Protein Isoforms Receptors Estrogen Tamoxifen Xenograft Model Antitumor Assays
A New Way to See a Bronchopleural Fistula
A 77-year-old man presented with five episodes of sepsis to different hospitals in the year after having a left lower lobectomy for squamous cell carcinoma. In the first two episodes, a rim-enhancing left pleural effusion was...
Levetiracetam-induced eosinophilic pneumonia.
Levetiracetam is widely regarded as a benign antiepileptic drug, compared to older antiepileptic medication. We report a case of eosinophilic pneumonia due to levetiracetam use in a non-smoking woman aged 59 years with no...
Civic Crowdfunding for Social Work Research
Civic crowdfunding for research purposes has been an emerging trend in scientific fields over the past few years. This article presents findings from a mixed methods analysis of 152 social science research projects that...
Identification of critical stacking faults in thin-film CdTe solar cells
Cadmium telluride (CdTe) is a p-type semiconductor used in thin-film solar cells. To achieve high light-to-electricity conversion, annealing in the presence of CdCl2 is essential, but the underlying mechanism is...
Elucidating the Mechanism of Fatigue Crack Acceleration Following the Occurrence of an Underload
Enrico Salvati, Tan Sui, Hongjia Zhang, Alexander J.G. Lunt, Kai Soon Fong, Xu Song, Alexander M. Korsunsky
Dec 01, 2016
Fatigue Crack Growth Rate (FCGR) is altered by a single anomalous load exceeding cyclic maximum (Overload) or compressive load below cyclic minimum (Underload). The authors study fatigue crack acceleration due to a single...
A Network Intrusion Detection Method for Various Information Systems Based on Federated and Deep Learning
Under the premise of ensuring data privacy, traditional network intrusion detection (NID) methods cannot achieve high accuracy for different types of intrusions. A NID method combining transformer and federated learning (FedL)...
Published by: IGI Global Scientific Publishing
Exploring Principals’ Instructional Leadership Practices in Malaysia
Purpose
The purpose of this paper is to outline the findings from a small-scale, exploratory, study of principals’ instructional leadership practice in Malaysian primary schools. The dimensions and functions of instructional...
The purpose of this paper is to outline the findings from a small-scale, exploratory, study of principals’ instructional leadership practice in Malaysian primary schools. The dimensions and functions of instructional...
Lattice-mismatched heteroepitaxy of IV-VI thin films on PbTe(001)
The chalcogenides of tin and lead (SnS, SnSe, SnTe, PbS, PbSe, and PbTe) have applications ranging from solar cells to thermoelectrics. Taking rocksalt structured PbTe(001) as the substrate, we explore the coherent...
A dynamic model for current-based nozzle condition monitoring in fused deposition modelling
Abstract: 3D printing and particularly fused deposition modelling (FDM) is widely used for prototyping and fabricating low-cost customised parts. However, present fused deposition modelling 3D printers have limited nozzle...
A Hierarchical Clustering Federated Learning System Based on Industry 4.0
This study proposes using dendrogram clustering as the basis to construct a federated learning system for A.I. model parameter updating. The authors adopted a private blockchain to accelerate downloads of the latest parameters...
Published by: IGI Global Scientific Publishing
Lattice-mismatched heteroepitaxy of IV-VI thin films on PbTe(001)
The chalcogenides of tin and lead (SnS, SnSe, SnTe, PbS, PbSe, and PbTe) have applications ranging from solar cells to thermoelectrics. Taking rocksalt structured PbTe(001) as the substrate, we explore the coherent...
Exploring Principals’ Instructional Leadership Practices in Malaysia
Purpose
The purpose of this paper is to outline the findings from a small-scale, exploratory, study of principals’ instructional leadership practice in Malaysian primary schools. The dimensions and functions of instructional...
The purpose of this paper is to outline the findings from a small-scale, exploratory, study of principals’ instructional leadership practice in Malaysian primary schools. The dimensions and functions of instructional...
Home Activity Recognition for Rural Elderly Based on Deep Learning and Smartphone Sensors
With the exacerbation of the rural aging population trend, home-based health monitoring for the rural elderly has become a societal focal point, demanding an effective technological means to elevate the level of rural elderly...
Published by: IGI Global Scientific Publishing
Moving Target Detection and Tracking Based on Improved FCM Algorithm
With the rapid development of computer intelligence technology, the majority of scholars have a great interest in the detection and tracking of moving targets in the field of video surveillance and have been involved in its...
Published by: IGI Global Scientific Publishing
|
|< |
< |
1 |