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Antioxidants and Life Style Changes- A Prevention Paradigm for Coronary Heart Disease Patients
Oxidative stress and lipid peroxidation of LDL-Cholesterol are the well documented causes of Atherosclerosis vis-à-vis cardiovascular disease. Early risk factor modifications using Flavonoids, Anti-oxidant vitamins, moderate...
Published by: IJHS Medical Association
Antioxidants and Life Style Changes- A Prevention Paradigm for Coronary Heart Disease Patients
Oxidative stress and lipid peroxidation of LDL-Cholesterol are the well documented causes of Atherosclerosis vis-à-vis cardiovascular disease. Early risk factor modifications using Flavonoids, Anti-oxidant vitamins, moderate...
Published by: IJHS Medical Association
COVID-19 in People With Schizophrenia
As the global burden of mortality from COVID-19 continues to rise, an understanding of who is most at risk of adverse outcomes is of paramount importance. Pre-existing cardiometabolic, renal and respiratory diseases as well as...
The genetic intractability of Symbiodinium microadriaticum to standard algal transformation methods.
Modern transformation and genome editing techniques have shown great success across a broad variety of organisms. However, no study of successfully applied genome editing has been reported in a dinoflagellate despite the first...
COVID-19 in People With Schizophrenia
As the global burden of mortality from COVID-19 continues to rise, an understanding of who is most at risk of adverse outcomes is of paramount importance. Pre-existing cardiometabolic, renal and respiratory diseases as well as...
Effect of evidence updates on key determinants of measles vaccination impact
Han Fu, Kaja Abbas, Petra Klepac, Kevin van Zandvoort, Hira Tanvir, Allison Portnoy, Mark Jit
Jan 07, 2022
BACKGROUND: Model-based estimates of measles burden and the impact of measles-containing vaccine (MCV) are crucial for global health priority setting. Recently, evidence from systematic reviews and database analyses have...
Dysglycaemia, Inflammation and Psychosis
Benjamin Ian Perry, Rachel Upthegrove, Andrew Thompson, Steven Marwaha, Stanley Zammit, Swaran Preet Singh, Golam Khandaker
Jun 05, 2018
BACKGROUND: Psychosis is associated with both dysglycaemia and low-grade inflammation, but population-based studies investigating the interplay between these factors are scarce. AIMS: (1) To explore the direction of association...
Calibration of complex models through Bayesian evidence synthesis
Decision-analytic models must often be informed using data that are only indirectly related to the main model parameters. The authors outline how to implement a Bayesian synthesis of diverse sources of evidence to calibrate the...
Markov models multiparameter evidence synthesis probabilistic sensitivity analysis simulation methods Algorithms Bayes Theorem Computer Simulation Cross-Sectional Studies Decision Support Techniques Female Human papillomavirus 16 Humans Markov Chains Models Statistical Papillomavirus Infections Probability Registries United Kingdom Uterine Cervical Neoplasms
Social recovery therapy in combination with early intervention services for enhancement of social recovery in patients with first-episode psychosis (SUPEREDEN3)
David Fowler, Jo Hodgekins, Paul French, Max Marshall, Nick Freemantle, Paul McCrone, Linda Everard, Anna Lavis, Peter B Jones, Tim Amos, Swaran Singh, Vimal Sharma, Max Birchwood
Feb 07, 2018
SUMMARY
Background: We conducted a randomised controlled trial to evaluate the efficacy of enhancing social recovery from First Episode Psychosis (FEP) by augmenting Early Intervention Service (EIS) provision with Social...
Prevention Clinical Research Brain Disorders Serious Mental Illness Rehabilitation Clinical Trials and Supportive Activities Mental Health 6 Evaluation of treatments and therapeutic interventions 6.6 Psychological and behavioural Mental Health Adolescent Adult Early Medical Intervention Female Humans Interpersonal Relations Male Mental Health Services Psychiatric Rehabilitation Psychotic Disorders Single-Blind Method Social Skills Treatment Outcome
Social Firms as a means of vocational recovery for people with mental illness
Eleanor Gilbert, Steven Marwaha, Alyssa Milton, Sonia Johnson, Nicola Morant, Nicholas Parsons, Adrian Fisher, Swaran Singh, Di Cunliffe
Jul 12, 2013
From early intervention in psychosis to youth mental health reform
Ashok Malla, Srividya Iyer, Patrick McGorry, Mary Cannon, Helen Coughlan, Swaran Singh, Peter Jones, Ridha Joober
Dec 02, 2015
Maternal immunisation against Group B Streptococcus
Simon R Procter, Bronner P Gonçalves, Proma Paul, Jaya Chandna, Farah Seedat, Artemis Koukounari, Raymond Hutubessy, Caroline Trotter, Joy E Lawn, Mark Jit
Apr 14, 2023
Background
Group B Streptococcus (GBS) can cause invasive disease (iGBS) in young infants, typically presenting as sepsis or meningitis, and is also associated with stillbirth and preterm birth. GBS vaccines are under...
Humans Streptococcus Agalactiae Streptococcal Infections premature birth vaccines Immunization Vaccination Bayes Theorem Pregnancy Quality of life Infant Infant Newborn Cost-Benefit Analysis Female Stillbirth
Published by: PLoS Medicine
Improved social functioning following social recovery therapy in first episode psychosis
Siân Lowri Griffiths, Stephen J Wood, David Fowler, Nick Freemantle, Joanne Hodgekins, Peter B Jones, Swaran Singh, Vimal Sharma, Max Birchwood
Feb 11, 2021
UNLABELLED: There is a need to develop and refine psychosocial interventions to improve functioning in First Episode Psychosis (FEP). Social cognition and neurocognition are closely linked to functioning in psychosis;...
Effect of evidence updates on key determinants of measles vaccination impact
Han Fu, Kaja Abbas, Petra Klepac, Kevin van Zandvoort, Hira Tanvir, Allison Portnoy, Mark Jit
Nov 22, 2021
BACKGROUND: Model-based estimates of measles burden and the impact of measles-containing vaccine (MCV) are crucial for global health priority setting. Recently, evidence from systematic reviews and database analyses have...
COVID-19 impact on routine immunisations for vaccine-preventable diseases
Jaspreet Toor, Xiang Li, Mark Jit, Caroline L Trotter, Susy Echeverria-Londono, Anna-Maria Hartner, Jeremy Roth, Allison Portnoy, Kaja Abbas, Neil M Ferguson, Katy Am Gaythorpe
Jul 08, 2022
Over the past two decades, vaccination programmes for vaccine-preventable diseases (VPDs) have expanded across low- and middle-income countries (LMICs). However, the rise of COVID-19 resulted in global disruption to routine...
Cost-effectiveness of early intervention services for psychosis and fidelity to national policy implementation guidance.
Muralikrishnan Radhakrishnan, Paul McCrone, Louise Lafortune, Linda Everard, David Fowler, Tim Amos, Nick Freemantle, Swaran P Singh, Max Marshall, Vimal Sharma, Anna Lavis, Peter B Jones, Max Birchwood
Dec 01, 2017
The impact of manic symptoms in first-episode psychosis
Steven Marwaha, Danielle Hett, Sonia Johnson, David Fowler, Joanne Hodgekins, Nick Freemantle, Paul McCrone, Linda Everard, Peter Jones, Tim Amos, Swaran Singh, Vimal Sharma, Max Birchwood
Apr 21, 2021
OBJECTIVE: The extant literature is inconsistent over whether manic symptoms in first-episode psychosis (FEP) impact on its development and trajectory. This study addressed the following: (1) Does Duration of Untreated Illness...
The course of negative symptom in first episode psychosis and the relationship with social recovery.
Brioney Gee, Jo Hodgekins, David Fowler, Max Marshall, Linda Everard, Helen Lester, Peter B Jones, Tim Amos, Swaran P Singh, Vimal Sharma, Nick Freemantle, Max Birchwood
May 24, 2016
Early intervention Functioning longitudinal negative symptoms recovery Adolescent Analysis of Variance Cost-Benefit Analysis Disease Progression Family Female Follow-Up Studies Genetic Predisposition to Disease Humans Longitudinal Studies Male Psychiatric Status Rating Scales Psychotic Disorders Regression Analysis Sex Factors Social Behavior Treatment Outcome United Kingdom Young Adult
Maternal immunisation against Group B Streptococcus
Simon R Procter, Bronner P Gonçalves, Proma Paul, Jaya Chandna, Farah Seedat, Artemis Koukounari, Raymond Hutubessy, Caroline Trotter, Joy E Lawn, Mark Jit
Mar 14, 2023
Impact of COVID-19-related disruptions to measles, meningococcal A, and yellow fever vaccination in 10 countries.
Katy AM Gaythorpe, Kaja Abbas, John Huber, Andromachi Karachaliou, Niket Thakkar, Kim Woodruff, Xiang Li, Susy Echeverria-Londono, Matthew Ferrari, Michael L Jackson, Kevin McCarthy, T Alex Perkins, Caroline Trotter, Mark Jit
Jul 28, 2021
Background
Childhood immunisation services have been disrupted by the COVID-19 pandemic. WHO recommends considering outbreak risk using epidemiological criteria when deciding whether to conduct preventive vaccination...
human Vaccination Medicine EPIDEMIOLOGY Measles Yellow Fever Global Health Meningococcal disease Mathematical modelling covid-19 Humans Meningococcal Infections Meningococcal Vaccines Measles Vaccine Yellow Fever Vaccine Risk Assessment Disease Outbreaks Adolescent Adult Child Child Preschool Infant Immunization Programs Africa Bangladesh Young Adult Pandemics covid-19 SARS-CoV-2
Published by: eLife
Genetic transformation of the dinoflagellate chloroplast.
Isabel C Nimmo, Adrian C Barbrook, Imen Lassadi, Jit Ern Chen, Katrin Geisler, Alison G Smith, Manuel Aranda, Saul Purton, Ross F Waller, R Ellen R Nisbet, Christopher J Howe
Jul 15, 2019
Coral reefs are some of the most important and ecologically diverse marine environments. At the base of the reef ecosystem are dinoflagellate algae, which live symbiotically within coral cells. Efforts to understand the...
Five-year illness trajectories across racial groups in the UK following a first episode psychosis.
Siân Lowri Griffiths, Tumelo Bogatsu, Mia Longhi, Emily Butler, Beel Alexander, Mrunal Bandawar, Linda Everard, Peter B Jones, David Fowler, Joanne Hodgekins, Tim Amos, Nick Freemantle, Paul McCrone, Swaran P Singh, Max Birchwood, Rachel Upthegrove
Apr 02, 2023
Structure and stability of symptoms in first episode psychosis
Enhanced and Holistic Voyage Planning Using Digital Twins
The chapter explains techniques and approaches to optimize a ship's voyage in terms of environmental and business parameters, utilizing the digital twin (DT) concept. It demonstrates how voyage planning and navigation...
Sustainable Development Business and Management Operations and Service Management Computer Science and Information Technology Life Sciences
Published by: IGI Global Scientific Publishing
Structure and stability of symptoms in first episode psychosis
Siân Lowri Griffiths, Samuel P Leighton, Pavan Kumar Mallikarjun, Georgina Blake, Linda Everard, Peter B Jones, David Fowler, Joanne Hodgekins, Tim Amos, Nick Freemantle, Vimal Sharma, Max Marshall, Paul McCrone, Swaran P Singh, Max Birchwood, Rachel Upthegrove
Jan 07, 2022
Early psychosis is characterised by heterogeneity in illness trajectories, where outcomes remain poor for many. Understanding psychosis symptoms and their relation to illness outcomes, from a novel network perspective, may help...
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