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Results: 92156
Single-dose BNT162b2 vaccine protects against asymptomatic SARS-CoV-2 infection.
Nick K Jones, Lucy Rivett, Shaun Seaman, Richard J Samworth, Ben Warne, Chris Workman, Mark Ferris, Jo Wright, Natalie Quinnell, Ashley Shaw, Cambridge COVID-19 Collaboration, Ian G Goodfellow, Paul J Lehner, Rob Howes, Giles Wright, Nicholas J Matheson, Michael P Weekes
Apr 09, 2021
The BNT162b2 mRNA COVID-19 vaccine (Pfizer-BioNTech) is being utilised internationally for mass COVID-19 vaccination. Evidence of single-dose protection against symptomatic disease has encouraged some countries to opt for...
Reminiscences of Biology 213-214
This collection of written reminiscences includes seven written accounts relating to the COVID-19 pandemic and 2020 experience, notably from the student perspective. Seven college students from a Winthrop Biology course...
Published by: Winthrop University
SARS-CoV-2 transmission risk from asymptomatic carriers
Paul Wilmes, Jacques Zimmer, Jasmin Schulz, Frank Glod, Lisa Veiber, Laurent Mombaerts, Bruno Rodrigues, Atte Aalto, Jessica Pastore, Chantal J Snoeck, Markus Ollert, Guy Fagherazzi, Joël Mossong, Jorge Goncalves, Alexander Skupin, Ulf Nehrbass
Feb 10, 2021
BACKGROUND: To accompany the lifting of COVID-19 lockdown measures, Luxembourg implemented a mass screening (MS) programme. The first phase coincided with an early summer epidemic wave in 2020. METHODS: rRT-PCR-based screening...
Single-dose BNT162b2 vaccine protects against asymptomatic SARS-CoV-2 infection
Nick K Jones, Lucy Rivett, Shaun Seaman, Richard J Samworth, Ben Warne, Chris Workman, Mark Ferris, Jo Wright, Natalie Quinnell, Ashley Shaw, Cambridge COVID-19 Collaboration, Ian G Goodfellow, Paul J Lehner, Rob Howes, Giles Wright, Nicholas J Matheson, Michael P Weekes, Amy Amory, Stephen Baker, Emma Bateman, Aklima Begum, Moushima Begum, John Bradley, Michael Brennan, Helen Burn, Caroline Crofts, Afzal Chaudhry, Yasmin Chaudhry, Daniel J Cooper, Sharon Dawson, Gordon Dougan, Renny Feather, Louise Free, Katie Friel, Claire Gildea, Iliana Georgana, Lizz Grimwade, Ravi Gupta, Susan Hall, Sophie Hannan, James Hayes, Aleksandra Hosaja, Myra Hosmillo, Rhys Izuagbe, Aminu Jahun, Lidia James, Jill Jardin, Nathalie Kingston, Sara Lear, Paul A Lyons, Patrick H Maxwell, Sue Mott, Sarah Mugavin, Joyce Mwiya, Sharon Peacock, Ravi Prakash Nallattil, Kazeem Oloyede, Willem H Ouwehand, Elle Page, Marina Perez, Tim Raine, Matthew Routledge, Caroline Saunders, Kenneth GC Smith, Dominic Sparkes, Maria Stafford, Charlotte Summers, Despiona Tatsi, James ED Thaventhiran, Sharon Thomas Johnson, M Estée Török, Mark Toshner, Lesley Turner, Kate Wall, Karis Watson
Apr 23, 2021
The BNT162b2 mRNA COVID-19 vaccine (Pfizer-BioNTech) is being utilised internationally for mass COVID-19 vaccination. Evidence of single-dose protection against symptomatic disease has encouraged some countries to opt for...
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission.
Dinesh Aggarwal, Ben Warne, Aminu S Jahun, William L Hamilton, Thomas Fieldman, Louis du Plessis, Verity Hill, Beth Blane, Emmeline Watkins, Elizabeth Wright, Grant Hall, Catherine Ludden, Richard Myers, Myra Hosmillo, Yasmin Chaudhry, Malte L Pinckert, Iliana Georgana, Rhys Izuagbe, Danielle Leek, Olisaeloka Nsonwu, Gareth J Hughes, Simon Packer, Andrew J Page, Marina Metaxaki, Stewart Fuller, Gillian Weale, Jon Holgate, Christopher A Brown, Cambridge Covid-19 testing Centre, University of Cambridge Asymptomatic COVID-19 Screening Programme Consortium, COVID-19 Genomics UK (COG-UK) Consortium, Rob Howes, Duncan McFarlane, Gordon Dougan, Oliver G Pybus, Daniela De Angelis, Patrick H Maxwell, Sharon J Peacock, Michael P Weekes, Chris Illingworth, Ewan M Harrison, Nicholas J Matheson, Ian G Goodfellow
Mar 13, 2022
Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative
Jan 05, 2022
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of...
Autoimmunity Body Mass Index covid-19 Critical Illness Female Genetic Loci Genetic Predisposition to Disease Genome-Wide Association Study Geographic Mapping Hospitalization Host-Pathogen Interactions Humans Inflammation Information Dissemination Male Multifactorial Inheritance Racial Groups SARS-CoV-2 Smoking
Written Reminiscences of Dorothea Jansen
These written responses were completed by Dorothea Jansen as part of Project 2020: A Collaborative Oral History. These recollections provide insight into the COVID-19 pandemic and critical year 2020, notably from the perspective...
Published by: Winthrop University
CSF Rhinorrhea After Endonasal Intervention to the Skull Base (CRANIAL) - Part 2
CRANIAL Consortium
Oct 20, 2021
BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, concerns have been raised regarding the increased risk of perioperative mortality for patients with COVID-19, and the transmission risk to healthcare workers...
CRANIAL Consortium Skull Base Nasal Cavity Humans Cerebrospinal Fluid Rhinorrhea Postoperative Complications endoscopy Mass Screening Neurosurgical Procedures Cohort Studies Prospective Studies Adolescent Adult Aged Aged 80 and over Middle Aged Child Ireland Female Male Young Adult Preoperative Period Personal protective equipment United Kingdom covid-19 COVID-19 Testing
An integrated national scale SARS-CoV-2 genomic surveillance network.
The Coronavirus Disease 2019 (COVID-19) Genomics UK Consortium (COG-UK) was launched in March, 2020, with £20 million support from UK Research and Innovation, the UK Department of Health and Social Care, and Wellcome Trust. The...
Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.
Nick K Jones, Lucy Rivett, Dominic Sparkes, Sally Forrest, Sushmita Sridhar, Jamie Young, Joana Pereira-Dias, Claire Cormie, Harmeet Gill, Nicola Reynolds, Michelle Wantoch, Matthew Routledge, Ben Warne, Jack Levy, William David Córdova Jiménez, Fathima Nisha Begum Samad, Chris McNicholas, Mark Ferris, Jane Gray, Michael Gill, CITIID-NIHR COVID-19 BioResource Collaboration, Martin D Curran, Stewart Fuller, Afzal Chaudhry, Ashley Shaw, John R Bradley, Gregory J Hannon, Ian G Goodfellow, Gordon Dougan, Kenneth GC Smith, Paul J Lehner, Giles Wright, Nicholas J Matheson, Stephen Baker, Michael P Weekes
Jun 24, 2020
Previously, we showed that 3% (31/1032)of asymptomatic healthcare workers (HCWs) from a large teaching hospital in Cambridge, UK, tested positive for SARS-CoV-2 in April 2020. About 15% (26/169) HCWs with symptoms of coronavirus...
covid-19 SARS-CoV-2 emerging pathogens EPIDEMIOLOGY Global Health human human biology infectious disease Medicine Occupational health Virology Adult Asymptomatic Diseases Betacoronavirus covid-19 COVID-19 Testing Clinical Laboratory Techniques Community-Acquired Infections Contact Tracing Coronavirus Infections Disease Transmission Infectious England Family Characteristics Female Health Personnel Hospital Units Hospitals Teaching Hospitals University Humans infection control Infectious Disease Transmission Patient-to-Professional Male Mass Screening Middle Aged nasopharynx Occupational Diseases Pandemics Patient Admission Pneumonia Viral prevalence Program Evaluation Real-Time Polymerase Chain Reaction SARS-CoV-2 Symptom Assessment
COVID-19 trajectories among 57 million adults in England
Johan H Thygesen, Christopher Tomlinson, Sam Hollings, Mehrdad A Mizani, Alex Handy, Ashley Akbari, Amitava Banerjee, Jennifer Cooper, Alvina G Lai, Kezhi Li, Bilal A Mateen, Naveed Sattar, Reecha Sofat, Ana Torralbo, Honghan Wu, Angela Wood, Jonathan AC Sterne, Christina Pagel, William N Whiteley, Cathie Sudlow, Harry Hemingway, Spiros Denaxas, Longitudinal Health and Wellbeing COVID-19 National Core Study and the CVD-COVID-UK/COVID-IMPACT Consortium
Jul 14, 2022
BACKGROUND: Updatable estimates of COVID-19 onset, progression, and trajectories underpin pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to define and validate ten COVID-19 phenotypes...
Harmonising electronic health records for reproducible research
Hoda Abbasizanjani, Fatemeh Torabi, Stuart Bedston, Thomas Bolton, Gareth Davies, Spiros Denaxas, Rowena Griffiths, Laura Herbert, Sam Hollings, Spencer Keene, Kamlesh Khunti, Emily Lowthian, Jane Lyons, Mehrdad A Mizani, John Nolan, Cathie Sudlow, Venexia Walker, William Whiteley, Angela Wood, Ashley Akbari, CVD-COVID-UK/COVID-IMPACT Consortium
Jan 16, 2023
BACKGROUND: The CVD-COVID-UK consortium was formed to understand the relationship between COVID-19 and cardiovascular diseases through analyses of harmonised electronic health records (EHRs) across the four UK nations. Beyond...
Harmonising electronic health records for reproducible research
Hoda Abbasizanjani, Fatemeh Torabi, Stuart Bedston, Thomas Bolton, Gareth Davies, Spiros Denaxas, Rowena Griffiths, Laura Herbert, Sam Hollings, Spencer Keene, Kamlesh Khunti, Emily Lowthian, Jane Lyons, Mehrdad A Mizani, John Nolan, Cathie Sudlow, Venexia Walker, William Whiteley, Angela Wood, Ashley Akbari, CVD-COVID-UK/COVID-IMPACT Consortium
Feb 17, 2023
BACKGROUND: The CVD-COVID-UK consortium was formed to understand the relationship between COVID-19 and cardiovascular diseases through analyses of harmonised electronic health records (EHRs) across the four UK nations. Beyond...
Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening.
Abiola Senok, Hanan Alsuwaidi, Yusrah Atrah, Ola Al Ayedi, Janan Al Zahid, Aaron Han, Asma Al Marzooqi, Saba Al Heialy, Basel Altrabulsi, Laila AbdelWareth, Youssef Idaghdour, Raghib Ali, Tom Loney, Alawi Alsheikh-Ali
Nov 20, 2020
PURPOSE: With the easing of restriction measures, repeated community-based sampling for tracking new COVID-19 infections is anticipated for the next 6 to 12 months. A non-invasive, self-collected specimen like saliva will be...
Samba II PCR testing for COVID-19 in pregnant women
Ruiling Xu, Tara Alicia Pauley, Hannah Missfelder-Lobos, Richard John Haddon, Ravindra Kumar Gupta, Hsu Phern Chong
Mar 17, 2021
Abstract: Background: Asymptomatic carriage of COVID-19 in pregnant women has been reported and could lead to outbreaks in maternity units. We sought to ascertain the impact of rapid isothernal nucleic acid based testing for...
The trans-omics landscape of COVID-19
Peng Wu, Dongsheng Chen, Wencheng Ding, Ping Wu, Hongyan Hou, Yong Bai, Yuwen Zhou, Kezhen Li, Shunian Xiang, Panhong Liu, Jia Ju, Ensong Guo, Jia Liu, Bin Yang, Junpeng Fan, Liang He, Ziyong Sun, Ling Feng, Jian Wang, Tangchun Wu, Hao Wang, Jin Cheng, Hui Xing, Yifan Meng, Yongsheng Li, Yuanliang Zhang, Hongbo Luo, Gang Xie, Xianmei Lan, Ye Tao, Jiafeng Li, Hao Yuan, Kang Huang, Wan Sun, Xiaobo Qian, Zhichao Li, Mingxi Huang, Peiwen Ding, Haoyu Wang, Jiaying Qiu, Feiyue Wang, Shiyou Wang, Jiacheng Zhu, Xiangning Ding, Chaochao Chai, Langchao Liang, Xiaoling Wang, Lihua Luo, Yuzhe Sun, Ying Yang, Zhenkun Zhuang, Tao Li, Lei Tian, Shaoqiao Zhang, Linnan Zhu, Ashley Chang, Lei Chen, Yiquan Wu, Xiaoyan Ma, Fang Chen, Yan Ren, Xun Xu, Siqi Liu, Huanming Yang, Lin Wang, Chaoyang Sun, Ding Ma, Xin Jin, Gang Chen
Jul 28, 2021
Abstract: The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without...
Modelling the impact of changes to abdominal aortic aneurysm screening and treatment services in England during the COVID-19 pandemic
Lois G. Kim, Michael J. Sweeting, Morag Armer, Jo Jacomelli, Akhtar Nasim, Seamus C. Harrison
Jun 17, 2021
Background: The National Health Service (NHS) abdominal aortic aneurysm (AAA) screening programme (NAAASP) in England screens 65-year-old men. The programme monitors those with an aneurysm, and early intervention for large...
Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England.
Quentin J Leclerc, Naomi M Fuller, Ruth H Keogh, Karla Diaz-Ordaz, Richard Sekula, Malcolm G Semple, ISARIC4C investigators, CMMID COVID-19 working group, Katherine E Atkins, Simon R Procter, Gwenan M Knight
Aug 02, 2021
BACKGROUND: Predicting bed occupancy for hospitalised patients with COVID-19 requires understanding of length of stay (LoS) in particular bed types. LoS can vary depending on the patient's "bed pathway" - the sequence of...
Samba II PCR testing for COVID-19 in pregnant women
Ruiling Xu, Tara Alicia Pauley, Hannah Missfelder-Lobos, Richard John Haddon, Ravindra Kumar Gupta, Hsu Phern Chong
May 10, 2021
BACKGROUND: Asymptomatic carriage of COVID-19 in pregnant women has been reported and could lead to outbreaks in maternity units. We sought to ascertain the impact of rapid isothernal nucleic acid based testing for COVID-19 in...
covid-19 Pregnancy SARS-CoV-2 Universal screening covid-19 COVID-19 Nucleic Acid Testing Carrier State Cohort Studies Cross Infection Female Hospitals Maternity Humans Mass Screening Point-of-care testing Pregnancy Pregnancy Complications Infectious Retrospective Studies SARS-CoV-2 Time Factors United Kingdom
The trans-omics landscape of COVID-19.
Peng Wu, Dongsheng Chen, Wencheng Ding, Ping Wu, Hongyan Hou, Yong Bai, Yuwen Zhou, Kezhen Li, Shunian Xiang, Panhong Liu, Jia Ju, Ensong Guo, Jia Liu, Bin Yang, Junpeng Fan, Liang He, Ziyong Sun, Ling Feng, Jian Wang, Tangchun Wu, Hao Wang, Jin Cheng, Hui Xing, Yifan Meng, Yongsheng Li, Yuanliang Zhang, Hongbo Luo, Gang Xie, Xianmei Lan, Ye Tao, Jiafeng Li, Hao Yuan, Kang Huang, Wan Sun, Xiaobo Qian, Zhichao Li, Mingxi Huang, Peiwen Ding, Haoyu Wang, Jiaying Qiu, Feiyue Wang, Shiyou Wang, Jiacheng Zhu, Xiangning Ding, Chaochao Chai, Langchao Liang, Xiaoling Wang, Lihua Luo, Yuzhe Sun, Ying Yang, Zhenkun Zhuang, Tao Li, Lei Tian, Shaoqiao Zhang, Linnan Zhu, Ashley Chang, Lei Chen, Yiquan Wu, Xiaoyan Ma, Fang Chen, Yan Ren, Xun Xu, Siqi Liu, Jian Wang, Huanming Yang, Lin Wang, Chaoyang Sun, Ding Ma, Xin Jin, Gang Chen
Aug 28, 2021
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without...
Assessing the impact of COVID-19 on liver cancer management (CERO-19).
Sergio Muñoz-Martínez, Victor Sapena, Alejandro Forner, Jean-Charles Nault, Gonzalo Sapisochin, Lorenza Rimassa, Bruno Sangro, Jordi Bruix, Marco Sanduzzi-Zamparelli, Wacław Hołówko, Mohamed El Kassas, Tudor Mocan, Mohamed Bouattour, Philippe Merle, Frederik JH Hoogwater, Saleh A Alqahtani, Helen L Reeves, David J Pinato, Emmanouil Giorgakis, Tim Meyer, Gerda Elisabeth Villadsen, Henning Wege, Massimiliano Salati, Beatriz Mínguez, Giovan Giuseppe Di Costanzo, Christoph Roderburg, Frank Tacke, María Varela, Peter R Galle, Mario Reis Alvares-da-Silva, Jörg Trojan, John Bridgewater, Giuseppe Cabibbo, Christian Toso, Anja Lachenmayer, Andrea Casadei-Gardini, Hidenori Toyoda, Tom Lüdde, Rosanna Villani, Ana María Matilla Peña, Cassia Regina Guedes Leal, Monica Ronzoni, Manuel Delgado, Christie Perelló, Sonia Pascual, José Luis Lledó, Josepmaria Argemi, Bristi Basu, Leonardo da Fonseca, Juan Acevedo, Alexander R Siebenhüner, Chiara Braconi, Brandon M Meyers, Alessandro Granito, Margarita Sala, Carlos Rodríguez-Lope, Lorraine Blaise, Manuel Romero-Gómez, Federico Piñero, Dhanny Gomez, Vivianne Mello, Rogerio Camargo Pinheiro Alves, Alex França, Fernanda Branco, Giovanni Brandi, Gustavo Pereira, Susanna Coll, Maria Guarino, Carlos Benítez, Maria Margarita Anders, Juan C Bandi, Mercedes Vergara, Mariona Calvo, Markus Peck-Radosavljevic, Ignacio García-Juárez, Vincenzo Cardinale, Mar Lozano, Martina Gambato, Stefano Okolicsanyi, Dalia Morales-Arraez, Alessandra Elvevi, Alberto E Muñoz, Alberto Lué, Massimo Iavarone, Maria Reig
Sep 02, 2021
BACKGROUND & AIMS: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the...
BCLC Barcelona Clinic Liver Cancer CERO-19 Liver Cancer Outcome in the COVID-19-pandemic Project covid-19 covid-19 Coronavirus disease 2019 Cholangiocarcinoma Clinical Trials ENS-CCA European Network for the Study of Cholangiocarcinoma HCC hepatocellular carcinoma hepatocellular carcinoma LC liver cancer LT liver transplantation Liver Cancer Management Nurses SARS-CoV-2 severe acute respiratory syndrome coronavirus-2 iCCA intrahepatic cholangiocarcinoma
Modelling the impact of changes to abdominal aortic aneurysm screening and treatment services in England during the COVID-19 pandemic.
Lois G Kim, Michael J Sweeting, Morag Armer, Jo Jacomelli, Akhtar Nasim, Seamus C Harrison
Jul 01, 2021
BACKGROUND: The National Health Service (NHS) abdominal aortic aneurysm (AAA) screening programme (NAAASP) in England screens 65-year-old men. The programme monitors those with an aneurysm, and early intervention for large...
Age Factors Aged Aortic Aneurysm Abdominal Aortic Rupture covid-19 Communicable Disease Control Computer Simulation Cost of Illness Elective Surgical Procedures England Health Policy Humans Male Mass Screening Models Statistical Pandemics Patient Acceptance of Health Care Risk Assessment Risk Factors Severity of Illness Index State Medicine Time-to-Treatment Ultrasonography
Interview with Deitre Owens Helvy
This interview was conducted by Winthrop student Michaela Bessinger with Deitre Owens Helvy as part of Project 2020: A Collaborative Oral History. Helvy details her experiences as a Black female educator in Greenville County...
Covid-19 pandemic 2020 Education Virtual learning Greenville County School District social justice race
Published by: Winthrop University
Pneumomediastinum in COVID-19
James Melhorn, Andrew Achaiah, Francesca M Conway, Elizabeth MF Thompson, Erik W Skyllberg, Joseph Durrant, Neda A Hasan, Yasser Madani, Prasheena Naran, Bavithra Vijayakumar, Matthew J Tate, Gareth E Trevelyan, Irfan Zaki, Catherine A Doig, Geraldine Lynch, Gill Warwick, Avinash Aujayeb, Karl A Jackson, Hina Iftikhar, Jonathan H Noble, Anthony YKC Ng, Mark Nugent, Philip J Evans, Robert A Hastings, Harry R Bellenberg, Hannah Lawrence, Rachel L Saville, Nikolas T Johl, Adam N Grey, Huw C Ellis, Cheng Chen, Thomas L Jones, Nadeem Maddekar, Shahul Leyakathali Khan, Ambreen Iqbal Muhammad, Hakim Ghani, Yadee Maung Maung Myint, Cecillia Rafique, Benjamin J Pippard, Benjamin RH Irving, Fawad Ali, Viola H Asimba, Aqeem Azam, Eleanor C Barton, Malvika Bhatnagar, Matthew P Blackburn, Kate J Millington, Nicholas J Budhram, Katherine L Bunclark, Toshit P Sapkal, Giles Dixon, Andrew JE Harries, Mohammad Ijaz, Vijayalakshmi Karunanithi, Samir Naik, Malik Aamaz Khan, Karishma Savlani, Vimal Kumar, Beatriz Lara Gallego, Noor A Mahdi, Caitlin Morgan, Neena Patel, Elen W Rowlands, Matthew S Steward, Richard S Thorley, Rebecca L Wollerton, Sana Ullah, David M Smith, Wojciech Lason, Anthony J Rostron, Najib M Rahman, Rob J Hallifax
Mar 14, 2022
BACKGROUND: There is an emerging understanding that coronavirus disease 2019 (COVID-19) is associated with increased incidence of pneumomediastinum. We aimed to determine its incidence among patients hospitalised with COVID-19...
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