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Receptor-targeting fluorescence imaging and theranostics using a graphene oxide based supramolecular glycocomposite

Intercellular glycoligand-receptor interactions are implicated in a number of disease-related processes. Effective tools that target these receptors may facilitate disease theranostics. However, owing to their low binding...

Receptor-targeting fluorescence imaging and theranostics using a graphene oxide based supramolecular glycocomposite

Intercellular glycoligand-receptor interactions are implicated in a number of disease-related processes. Effective tools that target these receptors may facilitate disease theranostics. However, owing to their low binding...

Targeted fluorescence imaging enhanced by 2D materials

Here we demonstrate that 2D MoS2 can enhance the receptor-targeting and imaging ability of a fluorophore-labelled ligand. The 2D MoS2 has an enhanced working concentration range when compared with...

Interface Coupling in Twisted Multilayer Graphene by Resonant Raman Spectroscopy of Layer Breathing Modes.
Raman spectroscopy is the prime nondestructive characterization tool for graphene and related layered materials. The shear (C) and layer breathing modes (LBMs) are due to relative motions of the planes, either perpendicular or...
Targeted fluorescence imaging enhanced by 2D materials

Here we demonstrate that 2D MoS2 can enhance the receptor-targeting and imaging ability of a fluorophore-labelled ligand. The 2D MoS2 has an enhanced working concentration range when compared with...

An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
MHC molecules are found in all jawed vertebrates and are known to present peptides to T lymphocytes. In mammals, peptides can hang out either end of the peptide-binding groove of classical class II molecules, whereas the N and C...
Design a Wireless Covert Channel Based on Dither Analog Chaotic Code
To conceal the very existence of communication, the noise-based wireless covert channel modulates secret messages into artificial noise, which is added to the normal wireless signal. Although the state-of-the-art work based on...
Board Tenure Diversity, Culture and Firm Risk
We examine the impact of board tenure diversity on firm risk in 37 countries. Using a difference-in-differences design facilitated by corporate board reforms across the world, we find that board tenure diversity leads to lower...
Characterizing Human Collective Behaviors During COVID-19 - Hong Kong SAR, China, 2020.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: People are likely to engage in collective behaviors online during extreme events, such as the coronavirus disease 2019 (COVID-19) crisis, to express awareness, take action, and work...
Board Tenure Diversity, Culture and Firm Risk
We examine the impact of board tenure diversity on firm risk in 37 countries. Using a difference-in-differences design facilitated by corporate board reforms across the world, we find that board tenure diversity leads to lower...
Resonant Raman spectroscopy of twisted multilayer graphene.
Graphene and other two-dimensional crystals can be combined to form various hybrids and heterostructures, creating materials on demand with properties determined by the interlayer interaction. This is the case even for a single...
Chemoselective Fluorogenic Bioconjugation of Vicinal Dithiol-Containing Proteins for Live Cellular Imaging via Small Molecular Conjugate Acceptors

To develop small molecular fluorogenic tools for the chemoselective labeling of vicinal dithiol-containing proteins (VDPs) in live cells is important for studying intracellular redox homeostasis. With this research, we...

Study on the Behavioral Motives of Algorithmic Avoidance in Intelligent Recommendation Systems
Through an exploration of the underlying mechanisms driving users' algorithmic avoidance in intelligent recommendation systems, this study aims to facilitate a positive interaction between users and technology, providing...
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues

The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...

Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization
Using the hydrothermal calcination method, bovine cancellous bone was transformed into a degradable macroporous scaffold with a nano-crystal surface microstructure, capable of releasing bioactive ions. Compared with the control...
Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization
Using the hydrothermal calcination method, bovine cancellous bone was transformed into a degradable macroporous scaffold with a nano-crystal surface microstructure, capable of releasing bioactive ions. Compared with the control...
Chemoselective Fluorogenic Bioconjugation of Vicinal Dithiol-Containing Proteins for Live Cellular Imaging via Small Molecular Conjugate Acceptors

To develop small molecular fluorogenic tools for the chemoselective labeling of vicinal dithiol-containing proteins (VDPs) in live cells is important for studying intracellular redox homeostasis. With this research, we...

Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells

With this research, we have developed two long-wavelength theranostic probes (DCMT and DCMC) with aggregation-induced emission (AIE)-based properties for image-guided photodynamic therapy (PDT) of hepatoma cells. Introduction...

Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues

The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...

Feasibility of Hybrid PSO-ANN Model for Identifying Soybean Diseases
Soybean disease has become one of vital factors restricting the sustainable development of high-yield and high-quality soybean industry. A hybrid artificial neural network (ANN) model optimized via particle swarm optimization...
Supramolecular polymer dot ensemble for ratiometric detection of lectins and targeted delivery of imaging agents

A supramolecular, polymer-dot-based ensemble has been developed for the ratiometric detection of lectins and targeted delivery of glycoprobes. Self-assembly between a blueemitting polymer dot and a red-emitting glycoprobe...

A Leucine Aminopeptidase-Activated Theranostic Prodrug for Cancer Diagnosis and Chemotherapy

Currently, chemotherapy is a widely used and important treatment for cancer. However, almost all of the treatments have shortcomings associated with poor specificity and high toxicity, which results in severe side effects to...

Supramolecular polymer dot ensemble for ratiometric detection of lectins and targeted delivery of imaging agents

A supramolecular, polymer-dot-based ensemble has been developed for the ratiometric detection of lectins and targeted delivery of glycoprobes. Self-assembly between a blueemitting polymer dot and a red-emitting glycoprobe...

Supramolecular glyco-poly-cyclodextrin functionalized thin-layer manganese dioxide for targeted stimulus-responsive bioimaging

We have developed a supramoleuclar imaging probe based on thin-layer manganese dioxide functionalized with a fluorescent, multivalent glyco-poly-cycolodextrin for the targeted, stimulus-responsive bioimaging of cancer...

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