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Results: 27802
Physiological responses during ascent to high altitude and the incidence of acute mountain sickness.
Alexandra B Cobb, Denny ZH Levett, Kay Mitchell, Wynne Aveling, Daniel Hurlbut, Edward Gilbert-Kawai, Philip J Hennis, Monty G Mythen, Michael PW Grocott, Daniel S Martin, Xtreme Everest 2009, Xtreme Everest 2 investigators Caudwell Xtreme Everest
May 31, 2021
Acute mountain sickness (AMS) occurs when there is failure of acclimatisation to high altitude. The aim of this study was to describe the relationship between physiological variables and the incidence of AMS during ascent to...
Caudwell Xtreme Everest
Konstadina Griva, Jan Stygall, Mark H Wilson, Daniel Martin, Denny Levett, Kay Mitchell, Monty Mythen, Hugh E Montgomery, Mike P Grocott, Golnar Aref-Adib, Mark Edsell, Tracie Plant, Chris Imray, Debbie Cooke, Jane Harrington, Maryam Khosravi, Stanton P Newman, Caudwell Xtreme Everest Research Group
Feb 22, 2019
BACKGROUND: The neuropsychological consequences of exposure to environmental hypobaric hypoxia (EHH) remain unclear. We thus investigated them in a large group of healthy volunteers who trekked to Mount Everest base camp (5,300...
The Smell of Hypoxia
Jonathan RN Lacey, Carlos Kidel, Jildou M van der Kaaij, Paul Brinkman, Edward T Gilbert-Kawai, Michael PW Grocott, Michael G Mythen, Daniel S Martin, Xtreme Everest 2 Research Group
Feb 06, 2019
Electronic nose (e-nose) devices may be used to identify volatile organic compounds (VOCs) in exhaled breath. VOCs generated via metabolic processes are candidate biomarkers of (patho)physiological pathways. We explored the...
The National Institute for Health Research
V Goh, National Institute for Health Research Clinical Research Network Imaging Network Steering Group, Royal College of Radiologists' Academic Committee
Oct 01, 2019
Since the inception of the National Institute for Health Research (NIHR) in 2006, the landscape for the delivery of clinical research within the National Health Service (NHS) has been transformed. Clinical radiology has...
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Lourdes Ortiz-Fernández, Francisco David Carmona, Raquel López-Mejías, Maria Francisca González-Escribano, Paul A Lyons, Ann W Morgan, Amr H Sawalha, Peter A Merkel, Kenneth GC Smith, Miguel A González-Gay, Javier Martín, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group Spanish GCA Study Group
Apr 18, 2018
OBJETIVE: Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we...
Autoantibodies outcomes research systemic sclerosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Case-Control Studies Epigenesis Genetic Female Genetic Loci Genetic Predisposition to Disease Giant Cell Arteritis HLA-DQ Antigens HLA-DQ beta-Chains Humans Jumonji Domain-Containing Histone Demethylases Linkage Disequilibrium Male Phenotype Polymorphism Single Nucleotide Protein Array Analysis Systemic Vasculitis Takayasu arteritis
Current opportunities to catalyze research in nutrition and cancer prevention – an interdisciplinary perspective
The Cancer Research UK - Ludwig Cancer Research Nutrition and Cancer Prevention Collaborative Group
Jul 31, 2019
Cancer Research UK and Ludwig Cancer Research convened an inaugural international Cancer Prevention and Nutrition Conference in London on December 3–4, 2018. Much of the discussion focused on the need for systematic...
cancer prevention Developmental origins Diet EPIDEMIOLOGY epigenetics interdisciplinary metabolism Nutrition obesity physical activity Public Health Biomedical Research Body Weight Congresses as Topic Diet Exercise food Humans Interdisciplinary Communication Interdisciplinary Research Neoplasms Nutrition Therapy Nutritional Status obesity Risk Factors United Kingdom
Relationship between islet autoantibody status and the clinical characteristics of children and adults with incident type 1 diabetes in a UK cohort.
Vassiliki Bravis, Akaal Kaur, Helen C Walkey, Ian F Godsland, Shivani Misra, Polly J Bingley, Alistair JK Williams, David B Dunger, Colin M Dayan, Mark Peakman, Nick S Oliver, Desmond G Johnston, Patient Advocate Group and Investigators ADDRESS-2 Management Committee
Jul 30, 2018
OBJECTIVES: To describe the characteristics of children and adults with incident type 1 diabetes in contemporary, multiethnic UK, focusing on differences between the islet autoantibody negative and positive. DESIGN...
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
Beyond dehydrocoupling
David J. Liptrot, Merle Arrowsmith, Annie L. Colebatch, Terrance J. Hadlington, Michael S. Hill, Gabriele Kociok-Kohn, Mary F. Mahon
Dec 07, 2015
The alkaline earth bis(trimethylsilyl)amides, [Ae{N(SiMe3)2}2(THF)2] [Ae = Mg, Ca, Sr], are effective pre-catalysts for boron-nitrogen bond formation through the desilacoupling of amines, RR’NH (R = alkyl, aryl; R′ = H, alkyl...
ENT audit and research in the era of trainee collaboratives.
Matthew E Smith, John Hardman, Matthew Ellis, Richard J Williams, The UK National ENT Trainee Research Network INTEGRATE
Sep 20, 2018
Large surgical audits and research projects are complex and costly to deliver, but increasingly surgical trainees are delivering these projects within formal collaboratives and research networks. Surgical trainee collaboratives...
Mesothelioma and Radical Surgery 2 (MARS 2)
Eric Lim, Liz Darlison, John Edwards, Daisy Elliott, DA Fennell, Sanjay Popat, Robert C Rintoul, David Waller, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Alan Kirk, Pek Koh, Kelvin Lau, Talal Mansy, Nick A Maskell, Richard Milton, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Paul Taylor, Sarah Treece, Kate Ashton, Rosie Harris, Katherine Joyce, Barbara Warnes, Nicola Mills, Elizabeth A Stokes, Chris Rogers, MARS 2 Trialists
Feb 08, 2021
INTRODUCTION: Mesothelioma remains a lethal cancer. To date, systemic therapy with pemetrexed and a platinum drug remains the only licensed standard of care. As the median survival for patients with mesothelioma is 12.1 months...
Beyond dehydrocoupling
David J. Liptrot, Merle Arrowsmith, Annie L. Colebatch, Terrance J. Hadlington, Michael S. Hill, Gabriele Kociok-Kohn, Mary F. Mahon
Dec 07, 2015
The alkaline earth bis(trimethylsilyl)amides, [Ae{N(SiMe3)2}2(THF)2] [Ae = Mg, Ca, Sr], are effective pre-catalysts for boron-nitrogen bond formation through the desilacoupling of amines, RR’NH (R = alkyl, aryl; R′ = H, alkyl...
Research in progress--LungSEARCH
UNLABELLED: Low-dose CT screening for lung cancer is effective but expensive. Therefore, cheaper or more focused screening strategies may be required. LungSEARCH is a randomised prospective trial of 1568 high-risk individuals...
Household Conflicts with Snow Leopard Conservation and Impacts from Snow Leopards in the Everest and Annapurna Regions of Nepal.
Jonathan H Hanson
Jun 07, 2022
Impacts on households from large carnivores are frequently reported in the conservation literature, but conflicts between households and large carnivore conservation are not. Employing a human-wildlife coexistence framework that...
What outcomes should researchers select, collect and report in pre-eclampsia research? A qualitative study exploring the views of women with lived experience of pre-eclampsia.
Jmn Duffy, T Thompson, L Hinton, M Salinas, RJ McManus, S Ziebland, International Collaboration to Harmonise Outcomes in Pre-eclampsia (iHOPE) Qualitative Research Group
Dec 18, 2020
OBJECTIVE: To identify outcomes relevant to women with lived experience of pre-eclampsia. DESIGN: Qualitative interview study. SETTING: A national study conducted in the United Kingdom. SAMPLE: Purposive sample of women with...
Setting national research priorities for difficult-to-treat depression in the UK between 2021-2026.
Natalya Chapman, Michael Browning, David Baghurst, Matthew Hotopf, Debbie Willis, Stuart Haylock, Sana Zakaria, Jan Speechley, James Withey, Edmund Brooks, Fiona Chan, Sofia Pappa, John Geddes, Lisa Insole, Zeid Mohammed, David Kessler, Peter B Jones, Parisa Mansoori, Difficult to Treat Depression Research Priority Setting Group
Jan 05, 2023
BACKGROUND: Difficult-to-treat depression (DTD) presents a substantial health care challenge, with around one-third of people diagnosed with a depressive episode in the UK finding that their symptoms persist following treatment....
Group for research and assessment of psoriasis and psoriatic arthritis
Laura C Coates, Arthur Kavanaugh, Philip J Mease, Enrique R Soriano, Maria Laura Acosta Felquer, April W Armstrong, Wilson Bautista Molano, Wolf-Henning Boehncke, Willemina Campbell, Alberto Cauli, Luis R Espinoza, Oliver FitzGerald, Dafna D Gladman, Alice Gottlieb, Philip S Helliwell, M Elaine Husni, Thorvardur J Love, Ennio Lubrano, Neil McHugh, Peter Nash, Alexis Ogdie, Ana-Maria Orbai, Andrew Parkinson, Denis O'Sullivan, Cheryl F Rosen, Sergio Schwartzman, Evan L Siegel, Sergio Toloza, William Tuong, Christopher T Ritchlin
May 01, 2016
OBJECTIVE: Update the 2009 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations for the spectrum of manifestations affecting patients with psoriatic arthritis...
Group for research and assessment of psoriasis and psoriatic arthritis
Laura C Coates, Arthur Kavanaugh, Philip J Mease, Enrique R Soriano, Maria Laura Acosta Felquer, April W Armstrong, Wilson Bautista Molano, Wolf-Henning Boehncke, Willemina Campbell, Alberto Cauli, Luis R Espinoza, Oliver FitzGerald, Dafna D Gladman, Alice Gottlieb, Philip S Helliwell, M Elaine Husni, Thorvardur J Love, Ennio Lubrano, Neil McHugh, Peter Nash, Alexis Ogdie, Ana-Maria Orbai, Andrew Parkinson, Denis O'Sullivan, Cheryl F Rosen, Sergio Schwartzman, Evan L Siegel, Sergio Toloza, William Tuong, Christopher T Ritchlin
May 01, 2016
OBJECTIVE: Update the 2009 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations for the spectrum of manifestations affecting patients with psoriatic arthritis...
The Neurology and Neurosurgery Interest Group (NANSIG)-ten years of cultivating interest in clinical neurosciences.
Jay J Park, Setthasorn Zhi Yang Ooi, Conor S Gillespie, Soham Bandyopadhyay, Yasir A Chowdhury, Georgios Solomou, Melissa Gough, Ulrick Sidney Kanmounye, Alvaro Yanez Touzet, Michael TC Poon, Andreas K Demetriades, Michael D Jenkinson, Alistair Jenkins, Neurology and Neurosurgery Interest Group (NANSIG)
Feb 18, 2022
Collaboration and successful teamworking are important components of clinical practise, and these skills should be cultivated early in medical school. The breadth of current medical school curricula means that students often...
Table of Contents
Winthrop McNair Research Bulletin
Jan 01, 0001
Winthrop McNair Research Bulletin Volume 5, Table of Contents
Published by: Winthrop University
The Neurology and Neurosurgery Interest Group (NANSIG)-ten years of cultivating interest in clinical neurosciences.
Jay J Park, Setthasorn Zhi Yang Ooi, Conor S Gillespie, Soham Bandyopadhyay, Yasir A Chowdhury, Georgios Solomou, Melissa Gough, Ulrick Sidney Kanmounye, Alvaro Yanez Touzet, Michael TC Poon, Andreas K Demetriades, Michael D Jenkinson, Alistair Jenkins, Neurology and Neurosurgery Interest Group (NANSIG)
Mar 31, 2022
Collaboration and successful teamworking are important components of clinical practise, and these skills should be cultivated early in medical school. The breadth of current medical school curricula means that students often...
Acknowledgements
Winthrop McNair Research Bulletin
Jan 01, 0001
Winthrop McNair Research Bulletin Volume 5, Acknowledgements
Published by: Winthrop University
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