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Results: 97148
Evaluation of a very brief pedometer-based physical activity intervention delivered in NHS Health Checks in England
Wendy Hardeman, Joanna Mitchell, Sally Pears, Miranda Van Emmenis, Florence Theil, Vijay S. Gc, Joana C. Vasconcelos, Kate Westgate, Søren Brage, Marc Suhrcke, Simon J. Griffin, Ann Louise Kinmonth, Edward C. F. Wilson, A. Toby Prevost, Stephen Sutton, on behalf of the VBI Research Team
Mar 06, 2020
Background: The majority of people do not achieve recommended levels of physical activity. There is a need for effective, scalable interventions to promote activity. Self-monitoring by pedometer is a potentially suitable...
Effectiveness and cost-effectiveness of a very brief physical activity intervention delivered in NHS Health Checks (VBI Trial)
Joanna Mitchell, Wendy Hardeman, Sally Pears, Joana C Vasconcelos, A Toby Prevost, Ed Wilson, Stephen Sutton, VBI Research Team
Jun 13, 2018
BACKGROUND: Physical activity interventions that are targeted at individuals can be effective in encouraging people to be more physically active. However, most such interventions are too long or complex and not scalable to the...
Accelerometry Cost-effectiveness analysis Pedometer physical activity Primary Health Care randomised controlled trial Very brief intervention Actigraphy Cardiovascular Diseases Clinical Protocols Cost-Benefit Analysis England Exercise Fitness Trackers Health Behavior Health Care Costs health status Humans Patient Education as Topic Primary Health Care Primary Prevention Research Design Risk Reduction Behavior Self Care State Medicine Time Factors Treatment Outcome
Comment on Herring et al. The Use of "Retardation" in FRAXA, FMRP, FMR1 and Other Designations. Cells 2022, 11, 1044.
This commentary is written in response to the recent article from Herring et al., discussing the eradication of the offensive term "retardation" from gene nomenclature. We discuss the work of the HUGO (Human Genome Organisation)...
A randomised controlled trial of three very brief interventions for physical activity in primary care
Evaluation of a very brief pedometer-based physical activity intervention delivered in NHS Health Checks in England
Wendy Hardeman, Joanna Mitchell, Sally Pears, Miranda Van Emmenis, Florence Theil, Vijay S Gc, Joana C Vasconcelos, Kate Westgate, Søren Brage, Marc Suhrcke, Simon J Griffin, Ann Louise Kinmonth, Edward Cf Wilson, A Toby Prevost, Stephen Sutton, VBI Research Team
Feb 06, 2020
BACKGROUND: The majority of people do not achieve recommended levels of physical activity. There is a need for effective, scalable interventions to promote activity. Self-monitoring by pedometer is a potentially suitable...
'Be on the TEAM' Study (Teenagers Against Meningitis)
Jeremy Carr, Emma Plested, Parvinder Aley, Susana Camara, Kimberly Davis, Jenny M MacLennan, Steve Gray, Saul N Faust, Ray Borrow, Hannah Christensen, Caroline Trotter, Martin CJ Maiden, Adam Finn, Matthew D Snape, ‘Be on the TEAM’ investigators
Oct 27, 2020
INTRODUCTION: Capsular group B Neisseria meningitidis (MenB) is the most common cause of invasive meningococcal disease (IMD) in many parts of the world. A MenB vaccine directed against the polysaccharide capsule remains elusive...
Paediatric infectious disease and immunisation paediatric intensive and critical care Infectious Diseases Paediatrics Adolescent Adult Humans Meningitis Meningococcal Infections Meningococcal Vaccines Neisseria meningitidis Neisseria meningitidis Serogroup B Randomized Controlled Trials as Topic State Medicine Vaccination Young Adult
Bridging Brain and Cognition
Ivan L. Simpson-Kent, Eiko I. Fried, Danyal Akarca, Silvana Mareva, Edward T. Bullmore, the CALM Team the CALM Team, Rogier A. Kievit
Jun 17, 2021
Network analytic methods that are ubiquitous in other areas, such as systems neuroscience, have recently been used to test network theories in psychology, including intelligence research. The network or mutualism theory of...
Did advice on the prescription of sodium valproate reduce prescriptions to women? An observational study in three European countries between 2007 and 2016
Rachel Charlton, Christine Damase-Michel, Caroline Hurault-Delarue, Rosa Gini, Maria Loane, Anna Pierini, Aurora Puccini, Amanda Neville, Julia Snowball, Joan Morris, on behalf of the EUROmediSAFE Consortium
Nov 01, 2019
Objectives
In November 2014, the CMDh (a regulatory body representing EU Member States) advised doctors not to prescribe sodium valproate for epilepsy or bipolar disorder in preg nant women, in women who can become pregnant...
In November 2014, the CMDh (a regulatory body representing EU Member States) advised doctors not to prescribe sodium valproate for epilepsy or bipolar disorder in preg nant women, in women who can become pregnant...
Did advice on the prescription of sodium valproate reduce prescriptions to women? An observational study in three European countries between 2007 and 2016
Rachel Charlton, Christine Damase-Michel, Caroline Hurault-Delarue, Rosa Gini, Maria Loane, Anna Pierini, Aurora Puccini, Amanda Neville, Julia Snowball, Joan Morris, on behalf of the EUROmediSAFE Consortium
Nov 01, 2019
Objectives
In November 2014, the CMDh (a regulatory body representing EU Member States) advised doctors not to prescribe sodium valproate for epilepsy or bipolar disorder in preg nant women, in women who can become pregnant...
In November 2014, the CMDh (a regulatory body representing EU Member States) advised doctors not to prescribe sodium valproate for epilepsy or bipolar disorder in preg nant women, in women who can become pregnant...
W404-010J-01 - Office of the Vice President for Academic Affairs: Office of Sponsored Programs and Research (SPAR): Correspondence and Memoranda
Office of Vice President for Academic Affairs, Sponsored Programs and Research, Office of, Grants and Sponsored Research Development, Office of
Jan 01, 0001
Published by: Winthrop University
Blood Pressure Changes Following Antihypertensive Medication Reduction, by Drug Class and Dose Chosen for Withdrawal
James P. Sheppard, Mark Lown, Jenni Burt, Gary A. Ford, F. D. Richard Hobbs, Paul Little, Jonathan Mant, Rupert A. Payne, Richard J. McManus, On behalf of the OPTiMISE Investigators
May 04, 2021
Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with polypharmacy, but there is little evidence to inform which drug (or dose) should be withdrawn. This study used data from the OPTiMISE...
Modifiable pathways in Alzheimer's disease
Susanna C Larsson, Matthew Traylor, Rainer Malik, Martin Dichgans, Stephen Burgess, Hugh S Markus, on behalf of the International Genomics of Alzheimer’s Project CoSTREAM Consortium
Mar 07, 2018
OBJECTIVE: To determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer's disease. DESIGN: Mendelian randomisation...
Dietary Patterns, Food Insecurity, and Their Relationships with Food Sources and Social Determinants in Two Small Island Developing States.
Divya Bhagtani, Eden Augustus, Emily Haynes, Viliamu Iese, Catherine R Brown, Jioje Fesaitu, Ian Hambleton, Neela Badrie, Florian Kroll, Arlette Saint-Ville, Thelma Alafia Samuels, Nita G Forouhi, Sara E Benjamin-Neelon, Nigel Unwin, On Behalf Of The CFaH Team
Sep 02, 2022
Small Island Developing States (SIDS) have high burdens of nutrition-related chronic diseases. This has been associated with lack of access to adequate and affordable nutritious foods and increasing reliance on imported foods....
The National Institute for Health Research
V Goh, National Institute for Health Research Clinical Research Network Imaging Network Steering Group, Royal College of Radiologists' Academic Committee
Oct 01, 2019
Since the inception of the National Institute for Health Research (NIHR) in 2006, the landscape for the delivery of clinical research within the National Health Service (NHS) has been transformed. Clinical radiology has...
CONSORT-SPI 2018 Explanation and Elaboration
Sean Grant, Evan Mayo-Wilson, Paul Montgomery, Geraldine Macdonald, Susan Michie, Sally Hopewell, David Moher, on behalf of the CONSORT-SPI Group
Jan 08, 2019
BACKGROUND: The CONSORT (Consolidated Standards of Reporting Trials) Statement was developed to help biomedical researchers report randomised controlled trials (RCTs) transparently. We have developed an extension to the CONSORT...
CONSORT randomised controlled trial Reporting guideline reporting standards Transparency Behavior Therapy Checklist Consensus Data Accuracy Delphi Technique Endpoint Determination Humans Outcome Assessment Health Care Randomized Controlled Trials as Topic Research Design Social Environment Treatment Outcome
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data
Lina Keutzer, Huifang You, Ali Farnoud, Joakim Nyberg, Sebastian G Wicha, Gareth Maher-Edwards, Georgios Vlasakakis, Gita Khalili Moghaddam, Elin M Svensson, Michael P Menden, Ulrika SH Simonsson, On Behalf Of The Unite Tb Consortium
Jul 23, 2022
Pharmacometrics (PM) and machine learning (ML) are both valuable for drug development to characterize pharmacokinetics (PK) and pharmacodynamics (PD). Pharmacokinetic/pharmacodynamic (PKPD) analysis using PM provides mechanistic...
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data
Lina Keutzer, Huifang You, Ali Farnoud, Joakim Nyberg, Sebastian G Wicha, Gareth Maher-Edwards, Georgios Vlasakakis, Gita Khalili Moghaddam, Elin M Svensson, Michael P Menden, Ulrika SH Simonsson, On Behalf Of The Unite Tb Consortium
Sep 02, 2022
Pharmacometrics (PM) and machine learning (ML) are both valuable for drug development to characterize pharmacokinetics (PK) and pharmacodynamics (PD). Pharmacokinetic/pharmacodynamic (PKPD) analysis using PM provides mechanistic...
Dietary Patterns, Food Insecurity, and Their Relationships with Food Sources and Social Determinants in Two Small Island Developing States.
Divya Bhagtani, Eden Augustus, Emily Haynes, Viliamu Iese, Catherine R Brown, Jioje Fesaitu, Ian Hambleton, Neela Badrie, Florian Kroll, Arlette Saint-Ville, Thelma Alafia Samuels, Nita G Forouhi, Sara E Benjamin-Neelon, Nigel Unwin, On Behalf Of The CFaH Team
Jul 19, 2022
Small Island Developing States (SIDS) have high burdens of nutrition-related chronic diseases. This has been associated with lack of access to adequate and affordable nutritious foods and increasing reliance on imported foods....
Multi-messenger Observations of a Binary Neutron Star Merger
LIGO Scientific Collaboration, Virgo Collaboration, GBM Fermi, INTEGRAL, IceCube Collaboration, AstroSat Cadmium Zinc Telluride Imager Team, IPN Collaboration, The Insight-Hxmt Collaboration, ANTARES Collaboration, The Swift Collaboration, AGILE Team, The 1M2H Team, The Dark Energy Camera GW-EM Collaboration, the DES Collaboration, The DLT40 Collaboration, GRAWITA, GRAvitational Wave Inaf TeAm, The Fermi Large Area Telescope Collaboration, ATCA, Australia Telescope Compact Array, ASKAP, Australian SKA Pathfinder, Las Cumbres Observatory Group, OzGrav, DWF, AST3, CAASTRO Collaborations, The VINROUGE Collaboration, MASTER Collaboration, J-GEM, GROWTH, JAGWAR, NRAO Caltech-, TTU-NRAO, NuSTAR Collaborations, Pan-STARRS, The MAXI Team, TZAC Consortium, KU Collaboration, Nordic Optical Telescope, ePESSTO, GROND, Texas Tech University, SALT Group, TOROS, Transient Robotic Observatory of the South Collaboration, The BOOTES Collaboration, MWA, Murchison Widefield Array, The CALET Collaboration, IKI-GW Follow-up Collaboration, H. E. S. S. Collaboration, LOFAR Collaboration, LWA, Long Wavelength Array, HAWC Collaboration, The Pierre Auger Collaboration, ALMA Collaboration, Euro VLBI Team, Pi of the Sky Collaboration, The Chandra Team at McGill University, DFN, Desert Fireball Network, ATLAS, High Time Resolution Universe Survey, RIMAS, RATIR, SKA South Africa/MeerKAT, Hendrik Van Eerten
Oct 16, 2017
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi...
Multi-messenger Observations of a Binary Neutron Star Merger
LIGO Scientific Collaboration, Virgo Collaboration, GBM Fermi, INTEGRAL, IceCube Collaboration, AstroSat Cadmium Zinc Telluride Imager Team, IPN Collaboration, The Insight-Hxmt Collaboration, ANTARES Collaboration, The Swift Collaboration, AGILE Team, The 1M2H Team, The Dark Energy Camera GW-EM Collaboration, the DES Collaboration, The DLT40 Collaboration, GRAWITA, GRAvitational Wave Inaf TeAm, The Fermi Large Area Telescope Collaboration, ATCA, Australia Telescope Compact Array, ASKAP, Australian SKA Pathfinder, Las Cumbres Observatory Group, OzGrav, DWF, AST3, CAASTRO Collaborations, The VINROUGE Collaboration, MASTER Collaboration, J-GEM, GROWTH, JAGWAR, NRAO Caltech-, TTU-NRAO, NuSTAR Collaborations, Pan-STARRS, The MAXI Team, TZAC Consortium, KU Collaboration, Nordic Optical Telescope, ePESSTO, GROND, Texas Tech University, SALT Group, TOROS, Transient Robotic Observatory of the South Collaboration, The BOOTES Collaboration, MWA, Murchison Widefield Array, The CALET Collaboration, IKI-GW Follow-up Collaboration, H. E. S. S. Collaboration, LOFAR Collaboration, LWA, Long Wavelength Array, HAWC Collaboration, The Pierre Auger Collaboration, ALMA Collaboration, Euro VLBI Team, Pi of the Sky Collaboration, The Chandra Team at McGill University, DFN, Desert Fireball Network, ATLAS, High Time Resolution Universe Survey, RIMAS, RATIR, SKA South Africa/MeerKAT, Hendrik Van Eerten
Oct 16, 2017
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi...
The underlying etiology of infantile spasms (West syndrome)
John P. Osborne, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin R. Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity, Finbar J. K. O'Callaghan, on behalf of the participating investigators
Sep 07, 2019
Objective
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
Methods
Identification of the underlying etiology and...
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
Methods
Identification of the underlying etiology and...
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