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Illicit and pharmaceutical drug consumption estimated via wastewater analysis. Part B: Placing back-calculations in a formal statistical framework
Hayley E Jones, Matthew Hickman, Barbara Kasprzyk-Hordern, Nicky J . Welton, David R. Baker, A. E Ades
Jul 15, 2014
Concentrations of metabolites of illicit drugs in sewage water can be measured with great accuracy and precision, thanks to the development of sensitive and robust analytical methods. Based on assumptions about factors including...
Illicit and pharmaceutical drug consumption estimated via wastewater analysis. Part B: Placing back-calculations in a formal statistical framework
Hayley E Jones, Matthew Hickman, Barbara Kasprzyk-Hordern, Nicky J . Welton, David R. Baker, A. E Ades
Jul 15, 2014
Concentrations of metabolites of illicit drugs in sewage water can be measured with great accuracy and precision, thanks to the development of sensitive and robust analytical methods. Based on assumptions about factors including...
Assessment of bisphenol-A in the urban water cycle
Bruce Petrie, Luigi Lopardo, Kathryn Proctor, Jane Youdan, Ruth Barden, Barbara Kasprzyk-Hordern
Feb 10, 2019
The plasticizer bisphenol-A (BPA) is common to municipal wastewaters and can exert toxicity to exposed organisms in the environment. Here BPA concentration at 5 sewage treatment works (STW) and distribution throughout a river...
Bisphenol-A industry Plasticizer River sludge Wastewater /dk/atira/pure/subjectarea/asjc/2300/2305 name=Environmental Engineering /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/2300/2311 name=Waste Management and Disposal /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution
A novel immobilization strategy for electrochemical detection of cancer biomarkers
We report on a novel strategy for DNA aptamer immobilization to develop sensitive electrochemical detection of protein biomarker, with prostate specific antigen (PSA) as a case biomarker. Thiolated single-stranded DNA was...
A novel immobilization strategy for electrochemical detection of cancer biomarkers
We report on a novel strategy for DNA aptamer immobilization to develop sensitive electrochemical detection of protein biomarker, with prostate specific antigen (PSA) as a case biomarker. Thiolated single-stranded DNA was...
Stereoselective biodegradation of amphetamine and methamphetamine in river microcosms
Here presented for the first time is the enantioselective biodegradation of amphetamine and methamphetamine in river microcosm bioreactors. The aim of this investigation was to test the hypothesis that mechanisms governing the...
Illicit and pharmaceutical drug consumption estimated via wastewater analysis. Part A
This paper presents, for the first time, community-wide estimation of drug and pharmaceuticals consumption in England using wastewater analysis and a large number of compounds. Among groups of compounds studied were: stimulants...
Illicit and pharmaceutical drug consumption estimated via wastewater analysis. Part A
This paper presents, for the first time, community-wide estimation of drug and pharmaceuticals consumption in England using wastewater analysis and a large number of compounds. Among groups of compounds studied were: stimulants...
Stereoselective biodegradation of amphetamine and methamphetamine in river microcosms
Here presented for the first time is the enantioselective biodegradation of amphetamine and methamphetamine in river microcosm bioreactors. The aim of this investigation was to test the hypothesis that mechanisms governing the...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Multi-residue analysis of drugs of abuse in wastewater and surface water by solid-phase extraction and liquid chromatography-positive electrospray ionisation tandem mass spectrometry
A new-multi residue method was developed for the environmental monitoring of 65 stimulants, opiod and morphine derivatives, benzodiazepines, antidepressants, dissociative anaesthetics, drug precursors, human urine indicators and...
Assessment of bisphenol-A in the urban water cycle
Bruce Petrie, Luigi Lopardo, Kathryn Proctor, Jane Youdan, Ruth Barden, Barbara Kasprzyk-Hordern
Feb 10, 2019
The plasticizer bisphenol-A (BPA) is common to municipal wastewaters and can exert toxicity to exposed organisms in the environment. Here BPA concentration at 5 sewage treatment works (STW) and distribution throughout a river...
Bisphenol-A industry Plasticizer River sludge Wastewater /dk/atira/pure/subjectarea/asjc/2300/2305 name=Environmental Engineering /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/2300/2311 name=Waste Management and Disposal /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution
Development of a filter to prevent infections with spore-forming bacteria in injecting drug users
Background
In heroin injectors, there have been a number of outbreaks caused by spore-forming bacteria, causing serious infections such as anthrax or botulism. These are, most likely, caused by injecting contaminated heroin...
In heroin injectors, there have been a number of outbreaks caused by spore-forming bacteria, causing serious infections such as anthrax or botulism. These are, most likely, caused by injecting contaminated heroin...
Enantiomeric profiling of chiral drugs in wastewater and receiving waters
The aim of this paper is to discuss the enantiomer-specific fate of chiral drugs during wastewater treatment and in receiving waters. Several chiral drugs were studied: amphetamine-like drugs of abuse (amphetamine...
Pharmacologically active compounds in the environment and their chirality
Barbara Kasprzyk-Hordern
Nov 01, 2010
Pharmacologically active compounds including both legally used pharmaceuticals and illicit drugs are potent environmental contaminants. Extensive research has been undertaken over the recent years to understand their...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Human population as a key driver of biochemical burden in an inter-city system
Barbara Kasprzyk-Hordern, Kathryn Proctor, Kishore Jagadeesan, Felicity Edler, Richard Standerwick, Ruth Barden
May 05, 2022
This paper tests the hypothesis that human population and city function are key drivers of biochemical burden in an inter-city system, which can be used to inform One Health actions as it enables a holistic understanding of...
AMR exposure Illicit Drugs lifestyle Pesticides Pharmaceuticals Wastewater-based Epidemiology Water fingerprinting /dk/atira/pure/subjectarea/asjc/2300/2305 name=Environmental Engineering /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/2300/2311 name=Waste Management and Disposal /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution /dk/atira/pure/subjectarea/asjc/2300/2307 name=Health, Toxicology and Mutagenesis /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
New Analytical Framework for Verification of Biomarkers of Exposure to Chemicals Combining Human Biomonitoring and Water Fingerprinting
Molecular epidemiology approaches in human biomonitoring are powerful tools that allow for verification of public exposure to chemical substances. Unfortunately, due to logistical difficulties and high cost, they tend to...
Development of a filter to prevent infections with spore-forming bacteria in injecting drug users
Background
In heroin injectors, there have been a number of outbreaks caused by spore-forming bacteria, causing serious infections such as anthrax or botulism. These are, most likely, caused by injecting contaminated heroin...
In heroin injectors, there have been a number of outbreaks caused by spore-forming bacteria, causing serious infections such as anthrax or botulism. These are, most likely, caused by injecting contaminated heroin...
Micropollutant fluxes in urban environment – A catchment perspective
Kathryn Proctor, Bruce Petrie, Luigi Lopardo, Dolores Camacho Muñoz, Jack Rice, Ruth Barden, Tom Arnot, Barbara Kasprzyk-Hordern
Jan 05, 2021
This study provided a holistic understanding of the sources, fate and behaviour of 142 compounds of emerging concern (CECs) throughout a river catchment impacted by 5 major urban areas. Of the incoming 169.3 kg d−1...
Chemicals of emerging concern Endocrine Disruptors Personal care products Pesticides Pharmaceuticals River solids Wastewater /dk/atira/pure/subjectarea/asjc/2300/2305 name=Environmental Engineering /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/2300/2311 name=Waste Management and Disposal /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution /dk/atira/pure/subjectarea/asjc/2300/2307 name=Health, Toxicology and Mutagenesis
Human population as a key driver of biochemical burden in an inter-city system
Barbara Kasprzyk-Hordern, Kathryn Proctor, Kishore Jagadeesan, Felicity Edler, Richard Standerwick, Ruth Barden
May 05, 2022
This paper tests the hypothesis that human population and city function are key drivers of biochemical burden in an inter-city system, which can be used to inform One Health actions as it enables a holistic understanding of...
AMR exposure Illicit Drugs lifestyle Pesticides Pharmaceuticals Wastewater-based Epidemiology Water fingerprinting /dk/atira/pure/subjectarea/asjc/2300/2305 name=Environmental Engineering /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/2300/2311 name=Waste Management and Disposal /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution /dk/atira/pure/subjectarea/asjc/2300/2307 name=Health, Toxicology and Mutagenesis /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Critical evaluation of methodology commonly used in sample collection, storage and preparation for the analysis of pharmaceuticals and illicit drugs in surface water and wastewater by solid phase extraction and liquid chromatography-mass spectrometry
The main aim of this manuscript is to provide a comprehensive and critical verification of methodology commonly used for sample collection, storage and preparation in studies concerning the analysis of pharmaceuticals and...
Estimation of community-wide drugs use via stereoselective profiling of sewage
This paper explores possibilities of applying enantiomeric profiling to solving problems related to estimation of drugs usage in communities via the sewage epidemiology approach: for the identification of whether drug residue...
Enantiomeric profiling of chiral drugs in wastewater and receiving waters
The aim of this paper is to discuss the enantiomer-specific fate of chiral drugs during wastewater treatment and in receiving waters. Several chiral drugs were studied: amphetamine-like drugs of abuse (amphetamine...
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
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