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Interview with Shannon Simpson
Shannon Simpson
Jan 01, 0001
In her June 12, 2013 interview with Martha Manning, Shannon Simpson detailed her time as an undergraduate student at Winthrop from 1995-1999. Discussed are details of Simpson's life as a student - residence halls, classes, meals...
Published by: Winthrop University
Why Your Mind Is Like a Shark
We want to understand how children get so much better at certain cognitive abilities like reading, writing, and problem solving as they get older. To better understand this, we followed hundreds of children across a period of...
Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.
Zhifen Chen, Haojie Yu, Xu Shi, Curtis R Warren, Luca A Lotta, Max Friesen, Torsten B Meissner, Claudia Langenberg, Martin Wabitsch, Nick Wareham, Mark D Benson, Rob E Gerszten, Chad A Cowan
Nov 25, 2019
Rationale: Genome-wide association studies have identified genetic loci associated with insulin resistance (IR) but pinpointing the causal genes of a risk locus has been challenging. Objective: To identify candidate causal genes...
Adipocytes Adipogenesis Diabetes mellitus Type 2 Insulin Resistance lipid metabolis Adaptor Proteins Signal Transducing Adipocytes Cell Line Dipeptidases Follistatin Genome-Wide Association Study Humans Insulin Receptor Substrate Proteins Insulin Resistance Loss of Function Mutation Lymphokines MAP Kinase Kinase Kinase 1 PPAR gamma Platelet-Derived Growth Factor Quantitative Trait Loci
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Evaluation of a weighting approach for performing sensitivity analysis after multiple imputation.
BACKGROUND: Multiple imputation (MI) is a well-recognised statistical technique for handling missing data. As usually implemented in standard statistical software, MI assumes that data are 'Missing at random' (MAR); an...
A Hierarchical Watershed Model of Fluid Intelligence in Childhood and Adolescence.
Fluid intelligence is the capacity to solve novel problems in the absence of task-specific knowledge and is highly predictive of outcomes like educational attainment and psychopathology. Here, we modeled the neurocognitive...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Barriers to the secondary use of data in critical care
Purpose: We explore the challenges of the secondary use of data in clinical information systems (CIS) which critical care units in the National Health Service (England) are facing.
Methods: We conducted an online survey of...
Cosmic hylomorphism
William MR Simpson
Jan 25, 2021
The primitive ontology approach to quantum mechanics seeks to account for quantum phenomena in terms of a distribution of matter in three-dimensional space (or four-dimensional spacetime) and a law of nature that describes its...
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect the patient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and if found...
Published by: IJHS Medical Association
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect thepatient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and iffound...
Published by: IJHS Medical Association
Regional disparities and seasonal differences in climate risk to rice labour.
The 880 million agricultural workers of the world are especially vulnerable to increasing heat stress due to climate change, affecting the health of individuals and reducing labour productivity. In this study, we focus on rice...
The neural determinants of age-related changes in fluid intelligence
Rogier A Kievit, Delia Fuhrmann, Gesa Sophia Borgeest, Ivan L Simpson-Kent, Richard NA Henson
Oct 05, 2018
Background: Fluid intelligence declines with advancing age, starting in early adulthood. Within-subject declines in fluid intelligence are highly correlated with contemporaneous declines in the ability to live and function...
Sentiment Analysis on Movie Reviews Dataset Using Support Vector Machines and Ensemble Learning
The internet makes it easier for people to connect to each other and has become a platform to express ideas and share information with the world. The growth of the internet has indirectly led to the development of social...
Published by: IGI Global Scientific Publishing
Right sided eventration of diaphragm with clinodactyly
A. Sareen and K. Mahajan
Apr 21, 2015
Diaphragmatic hernia can be of two types-absence or deficiency of the diaphragm, or eventration resulting in elevation of a portion of the diaphragm as a result of incomplete muscularization. Complete eventration almost...
Published by: IJHS Medical Association
Knowledge and Attitude among High School Students towards HIV / AIDS in Rural areas of Belagavi–A Cross Sectional Study
Asha A. Bellad and Rajesh R Kulkarni
Mar 25, 2015
Introduction Since its emergence in 1981, the HIV/AIDS pandemic, which poses a serious challenge to mankind, without doubt, has become one of the most serious infectious diseases. Many adolescents around the world are sexually...
Published by: IJHS Medical Association
SGBS cells as a model of human adipocyte browning
Chia Rou Yeo, Madhur Agrawal, Shawn Hoon, Asim Shabbir, Manu Kunaal Shrivastava, Shiqi Huang, Chin Meng Khoo, Vanna Chhay, M Shabeer Yassin, E Shyong Tai, Antonio Vidal-Puig, Sue-Anne Toh
Oct 09, 2020
The Simpson Golabi Behmel Syndrome (SGBS) pre-adipocyte cell strain is widely considered to be a representative in vitro model of human white pre-adipocytes. A recent study suggested that SGBS adipocytes exhibit an unexpected...
Knowledge and Attitude among High School Students towards HIV / AIDS in Rural areas of Belagavi–A Cross Sectional Study
Asha A. Bellad and Rajesh R Kulkarni
Mar 25, 2015
Introduction Since its emergence in 1981, the HIV/AIDS pandemic, which poses a serious challenge to mankind, without doubt, has become one of the most serious infectious diseases. Many adolescents around the world are sexually...
Published by: IJHS Medical Association
A combination of mutations in AKR1D1 and SKIV2L in a family with severe infantile liver disease.
Neil V Morgan, Jane L Hartley, Kenneth DR Setchell, Michael A Simpson, Rachel Brown, Louise Tee, Sian Kirkham, Shanaz Pasha, Richard C Trembath, Eamonn R Maher, Paul Gissen, Deirdre A Kelly
May 20, 2013
Sustainable Supply Chain Management Practices in Ghana
The study assessed the sustainable supply chain management (SSCM) practices of 303 manufacturing firms in Ghana with an annual turnover of not less than $1,000,000, which were purposively selected for the study. A questionnaire...
Published by: Indonesia Strategic Sustainability
Right sided eventration of diaphragm with clinodactyly
A. Sareen and K. Mahajan
Apr 21, 2015
Diaphragmatic hernia can be of two types-absence or deficiency of the diaphragm, or eventration resulting in elevation of a portion of the diaphragm as a result of incomplete muscularization. Complete eventration almost...
Published by: IJHS Medical Association
Health impacts of flooding in Lewes
M Reacher, K Mckenzie, C Lane, T Nichols, I Kedge, A Iversen, P Hepple, T Walter, C Laxton, J Simpson
Jun 02, 2021
Severe flooding may become more frequent due to global warming. A
historical cohort study was conducted by telephone interview for new episodes of
illness in all age groups, and for psychological distress in adults, following...
Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads.
Carolin A Müller, Michael A Boemo, Paolo Spingardi, Benedikt M Kessler, Skirmantas Kriaucionis, Jared T Simpson, Conrad A Nieduszynski
Jan 31, 2020
Replication of eukaryotic genomes is highly stochastic, making it difficult to determine the replication dynamics of individual molecules with existing methods. We report a sequencing method for the measurement of replication...
A national survey of the diagnosis and management of suspected ventilator-associated pneumonia.
Emma Browne, Thomas P Hellyer, Simon V Baudouin, Andrew Conway Morris, Vanessa Linnett, Danny F McAuley, Gavin D Perkins, A John Simpson
Jun 26, 2020
BACKGROUND: Ventilator-associated pneumonia (VAP) affects up to 20% of patients admitted to intensive care units (ICU). It is associated with increased morbidity, mortality and healthcare costs. Despite published guidelines...
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