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Nancy Hinson Cox

Jan 01, 0001

In her July 16, 1974 interview with Ann Yarborough Evans, Nancy Cox recalls Winthrop customs from 1930-1934. This interview was conducted for inclusion into the Louise Pettus Archives and Special Collections Oral History Program.

Home economics teaching Dorm Life Rules and Regulations daisy chain blue line McLaurin Lancaster Swimming religion Oral History

Published by: Winthrop University

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Cancer Markers Selection Using Network-Based Cox Regression

Antonella Iuliano, Annalisa Occhipinti, Claudia Angelini, Italia De Feis, Pietro Lió

Mar 20, 2019

International initiatives such as the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) are collecting multiple datasets at different genome-scales with the aim of identifying novel cancer...

Cox model Cancer Gene Expression high-dimensionality Network regularization survival

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APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS.

Alba Signes, Raffaele Cerutti, Anna S Dickson, Cristiane Benincá, Elizabeth C Hinchy, Daniele Ghezzi, Rosalba Carrozzo, Enrico Bertini, Michael P Murphy, James A Nathan, Carlo Viscomi, Erika Fernandez-Vizarra, Massimo Zeviani

Dec 21, 2018

Loss-of-function mutations in APOPT1, a gene exclusively found in higher eukaryotes, cause a characteristic type of cavitating leukoencephalopathy associated with mitochondrial cytochrome c oxidase (COX) deficiency. Although the...

APOPT1‐COA8 cytochrome c oxidase mitochondrial encephalopathy proteasome–ubiquitin system Reactive Oxygen Species Animals Apoptosis Regulatory Proteins Cells Cultured Electron Transport Complex IV Genetic Complementation Test Humans Mice Mice Knockout Mitochondrial Proteins Protein Multimerization Reactive Oxygen Species Unfolded Protein Response

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On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale

Alexander M. G. Cox, Jan Obłój

Aug 01, 2015

We study the joint laws of a continuous, uniformly integrable martingale, its maximum, and its minimum. In particular, we give explicit martingale inequalities which provide upper and lower bounds on the joint exit probabilities...

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On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale

Alexander M. G. Cox, Jan Obłój

Aug 01, 2015

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Robust Hedging of Options on a Leveraged Exchange Traded Fund

Alexander M. G. Cox, Sam M. Kinsley

Feb 01, 2019

A leveraged exchange traded fund (LETF) is an exchange traded fund that uses financial derivatives to amplify the price changes of a basket of goods. In this paper, we consider the robust hedging of European options on a...

Leveraged exchange traded fund monotonicity principle Optimal Skorokhod embedding problem Robust pricing and Hedging /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/1800/1804 name=Statistics, Probability and Uncertainty

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Robust Hedging of Options on a Leveraged Exchange Traded Fund

Alexander M. G. Cox, Sam M. Kinsley

Feb 01, 2019

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Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation.

Dan Jackson, Ian R White, Shaun Seaman, Hannah Evans, Kathy Baisley, James Carpenter

Jun 14, 2018

The Cox proportional hazards model is frequently used in medical statistics. The standard methods for fitting this model rely on the assumption of independent censoring. Although this is sometimes plausible, we often wish to...

Schoenfeld residuals bootstrapping informative censoring Multiple imputation sensitivity analysis Survival Analysis Acyclovir Adolescent Adult Antiviral Agents Bias Biometry Computer Simulation Female HIV Infections Herpes Genitalis Herpesvirus 2 Human Humans Monte Carlo Method Proportional Hazards Models Randomized Controlled Trials as Topic Regression Analysis Tanzania Young Adult

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Going off grid

D. Simpson, Janine B. Illian, F. Lindgren, S. H. Sorbye, H. Rue

Mar 01, 2016

This paper introduces a new method for performing computational inference on log-Gaussian Cox processes. The likelihood is approximated directly by making novel use of a continuously specified Gaussian random field. We show that...

Approximation of Gaussian random fields Gaussian Markov random field Integrated nested Laplace approximation Spatial point process Stochastic partial differential equation

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Going off grid

D. Simpson, Janine B. Illian, F. Lindgren, S. H. Sorbye, H. Rue

Mar 01, 2016

Approximation of Gaussian random fields Gaussian Markov random field Integrated nested Laplace approximation Spatial point process Stochastic partial differential equation

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Martingale optimal transport with stopping

Erhan Bayraktar, Alexander M.G. Cox, Yavor Stoev

Jan 01, 0001

We solve the martingale optimal transport problem for cost functionals represented by optimal stopping problems. The measure-valued martingale approach developed in [A. M. G. Cox and S. Källblad, SIAM J. Control Optim., 55...

math.PR 60G40 93E20 91A10 91A60 60G07

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Martingale optimal transport with stopping

Erhan Bayraktar, Alexander M.G. Cox, Yavor Stoev

Jan 01, 0001

math.PR 60G40 93E20 91A10 91A60 60G07

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Discretisation and Duality of Optimal Skorokhod Embedding Problems

Alexander M. G. Cox, Sam M. Kinsley

Jul 31, 2018

We prove a strong duality result for a linear programming problem which has the interpretation of being a discretised optimal Skorokhod embedding problem, and we recover this continuous time problem as a limit of the discrete...

/dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics

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Discretisation and Duality of Optimal Skorokhod Embedding Problems

Alexander M. G. Cox, Sam M. Kinsley

Jul 31, 2018

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Cover Image for Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines.

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Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines.

Agata Tarczykowska, Niklas Engström, Darja Dobermann, Jonathan Powell, Nathalie Scheers

Apr 17, 2023

We previously showed that two iron compounds that are orally ingested by humans, namely ferric EDTA and ferric citrate, can induce an oncogenic growth factor (amphiregulin) in human intestinal epithelial adenocarcinoma cell...

Iron IL-6 IGF1R COX-2 amphiregulin IFNGR1 ferric pyrophosphate Cell Line Humans Adenocarcinoma Iron Compounds Ferric Compounds Salts Edetic Acid Interleukin-6 Iron Chelating Agents Signal Transduction STAT Transcription Factors Cyclooxygenase 2 Janus Kinases Biomarkers

Published by: International journal of molecular sciences

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The geometry of multi-marginal Skorokhod Embedding

Mathias Beiglboeck, Alexander Cox, Martin Huesmann

Apr 30, 2020

The Skorokhod Embedding Problem is one of the classical problems in the theory of stochastic processes, with applications in many different fields [cf. the surveys (Hobson in: Paris-Princeton lectures on mathematical finance...

math.PR q-fin.PR 60G42 60G44 91G20

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Cover Image for High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation

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High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation

S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein

Apr 14, 2023

Clinical Research Clinical Trials and Supportive Activities Pediatric Research Initiative Cardiovascular

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The geometry of multi-marginal Skorokhod Embedding

Mathias Beiglboeck, Alexander Cox, Martin Huesmann

Apr 30, 2020

math.PR q-fin.PR 60G42 60G44 91G20

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Conflicting demands on a modern healthcare service

Zoë Fritz, Caitríona Cox

Jan 17, 2019

ethics Health Services Physician-Patient Relations Policy social justice Decision Making Delivery of Health Care Ethical Theory Health Services Administration National Health Programs Policy Making State Medicine

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Three-dimensional structure of the nasal passageway of a hagfish and its implications for olfaction

W M Holmes, R Cotton, V B Xuan, A D Rygg, B A Craven, R L Abel, R Slack, Jonathan P L Cox

Jun 01, 2011

From high-resolution (65 mu m) data acquired by magnetic resonance imaging, we have reconstructed the nasal passageway of a single adult hagfish specimen (probably Eptatretus stoutii). We have used this reconstruction to...

Diffusion Eptatretus Magnetic Resonance Imaging olfactory ability odorant transport fluid movement

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A multicentre assessment of prostate MRI quality and compliance with UK and international standards.

PR Burn, SJ Freeman, A Andreou, N Burns-Cox, R Persad, T Barrett

Apr 05, 2019

AIM: To assess prostate magnetic resonance imaging (MRI) image quality and compliance with technical standards between centres in the South West region of the UK. MATERIALS AND METHODS: Fifteen imaging sites in the region...

Equipment Design Humans Magnetic Resonance Imaging Male Professional Practice Prostatic Neoplasms Quality of Health Care Reference Standards United Kingdom

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The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling.

Alice A Torres, Stephanie L Macilwee, Amir Rashid, Sarah E Cox, Jonas D Albarnaz, Claudio A Bonjardim, Geoffrey Smith

Feb 24, 2022

Cellular proteins often have multiple and diverse functions. This is illustrated with protein Spir-1 that is an actin nucleator, but, as shown here, also functions to enhance innate immune signalling downstream of RNA sensing by...

RESEARCH ARTICLE Biology and life sciences Research and analysis methods Medicine and Health Sciences

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Quantifying the association between ethnicity and COVID-19 mortality

Hajira Dambha-Miller, Pui San Tan, Defne Saatci, Ashley Kieran Clift, Francesco Zaccardi, Carol Coupland, Patrick Locufier, Firoza Davies, Kamlesh Khunti, Simon J Griffin, Julia Hippisley-Cox

Apr 26, 2021

INTRODUCTION: Recent evidence suggests that ethnic minority groups are disproportionately at increased risk of hospitalisation and death from SARS-CoV-2 infection. Population-based evidence on potential explanatory factors...

covid-19 EPIDEMIOLOGY Public Health Adult covid-19 England Ethnicity Humans Minority Groups Retrospective Studies

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The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling.

Alice A Torres, Stephanie L Macilwee, Amir Rashid, Sarah E Cox, Jonas D Albarnaz, Claudio A Bonjardim, Geoffrey L Smith

Mar 14, 2022

Actins Animals Immunity Innate Mice Phenylalanine Signal Transduction vaccinia virus Viral Proteins Zika Virus Zika Virus Infection

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Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation

Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee

Nov 23, 2021

Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...

Paper Bayesian optimisation Gaussian processes heteroscedasticity

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