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Pharmaceutical Inhibition of mTOR in the Common Marmoset
Background: Inhibition of mechanistic target of rapamycin (mTOR) has emerged as a viable means to lengthen lifespan and healthspan in mice, although it is still unclear whether these benefits will extend to other mammalian...
Pharmaceutical Inhibition of mTOR in the Common Marmoset
Background: Inhibition of mechanistic target of rapamycin (mTOR) has emerged as a viable means to lengthen lifespan and healthspan in mice, although it is still unclear whether these benefits will extend to other mammalian...
Pharmaceutical Inhibition of mTOR in the Common Marmoset
Background: Inhibition of mechanistic target of rapamycin (mTOR) has emerged as a viable means to lengthen lifespan and healthspan in mice, although it is still unclear whether these benefits will extend to other mammalian...
Optimising the counting times for sample-in-container scattering experiments
A method is given for choosing the relative counting times, for the sample-in-
container and empty container parts of a fixed-duration scattering experiment, in
order to minimise the statistical error on the...
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Optimising the counting times for sample-in-container scattering experiments
A method is given for choosing the relative counting times, for the sample-in-
container and empty container parts of a fixed-duration scattering experiment, in
order to minimise the statistical error on the...
Published by:
Metabolic Consequences of Long-Term Rapamycin Exposure on Common Marmoset Monkeys (Callithrix Jacchus)
Rapamycin has been shown to extend lifespan in rodent models, but the effects on metabolic health and function have been widely debated in both clinical and translational trials. Prior to rapamycin being used as a treatment to...
Neutron diffraction as a probe of liquid and glass structures under extreme conditions
Neutrons provide a unique tool for probing the structure of liquid and glassy materials, and deliver information that cannot be obtained from other experimental techniques. Advances in neutron diffraction instrumentation and...
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Barnes et al. Reply
A Reply to the Comment by G. N. Greaves et al.

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Metabolic Consequences of Long-Term Rapamycin Exposure on Common Marmoset Monkeys (Callithrix Jacchus)
Rapamycin has been shown to extend lifespan in rodent models, but the effects on metabolic health and function have been widely debated in both clinical and translational trials. Prior to rapamycin being used as a treatment to...
Liquid-liquid phase transition in supercooled yttria-alumina
The structure and thermal characteristics of aerodynamically levitated samples of yttria-alumina in the liquid, supercooled liquid and solid phases were explored in an extensive series of high energy x-ray diffraction, small...
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Liquid-liquid phase transition in supercooled yttria-alumina
The structure and thermal characteristics of aerodynamically levitated samples of yttria-alumina in the liquid, supercooled liquid and solid phases were explored in an extensive series of high energy x-ray diffraction, small...
Published by:
High-Pressure Transformation of SiO<sub>2</sub> Glass from a Tetrahedral to an Octahedral Network
A combination of in situ high-pressure neutron diffraction at pressures up to 17.5(5) GPa and molecular dynamics simulations employing a many-body interatomic potential model is used to investigate the structure of...
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Recent advances in identifying the structure of liquid and glassy oxide and chalcogenide materials under extreme conditions
The advent of advanced instrumentation and measurement
protocols makes it increasingly feasible to use X-ray and
neutron diffraction methods to investigate the structure
of liquid and glassy materials under extreme...
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Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
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Neutron diffraction as a probe of liquid and glass structures under extreme conditions
Neutrons provide a unique tool for probing the structure of liquid and glassy materials, and deliver information that cannot be obtained from other experimental techniques. Advances in neutron diffraction instrumentation and...
Published by:
High-Pressure Transformation of SiO<sub>2</sub> Glass from a Tetrahedral to an Octahedral Network
A combination of in situ high-pressure neutron diffraction at pressures up to 17.5(5) GPa and molecular dynamics simulations employing a many-body interatomic potential model is used to investigate the structure of...
Published by:
Metabolic Consequences of Long-Term Rapamycin Exposure on Common Marmoset Monkeys (Callithrix Jacchus)
Rapamycin has been shown to extend lifespan in rodent models, but the effects on metabolic health and function have been widely debated in both clinical and translational trials. Prior to rapamycin being used as a treatment to...
Skills Mismatch or Skills Mishmash?
Michael Salmon
Sep 30, 2024

The valorization of skills in English higher education policy-making is a long-standing refrain, informing both rhetoric and investment from government and shaping university behaviour. Critiques of the ‘skills agenda’ are...

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Structure and triclustering in Ba-Al-O glass
Glass-forming ability in the (BaO) x(Al 2O 3) 1-x system (0≤x≤1) was investigated by using the containerless aerodynamic levitation and laser-heating method. The main glass-forming region was found to occur for 0.40(2) ≤x≤...
Published by:
Barnes et al. Reply
A Reply to the Comment by G. N. Greaves et al.

Published by:
Skills Mismatch or Skills Mishmash?
Michael Salmon
Sep 30, 2024

The valorization of skills in English higher education policy-making is a long-standing refrain, informing both rhetoric and investment from government and shaping university behaviour. Critiques of the ‘skills agenda’ are...

Published by:

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