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Results: 764
The widespread use of topical antimicrobials enriches for resistance in Staphylococcus aureus isolated from patients with atopic dermatitis.
CP Harkins, MA McAleer, D Bennett, M McHugh, OM Fleury, KA Pettigrew, K Oravcová, J Parkhill, CM Proby, RS Dawe, JA Geoghegan, AD Irvine, MTG Holden
Aug 20, 2019
BACKGROUND: Carriage rates of Staphylococcus aureus on affected skin in atopic dermatitis (AD) are approximately 70%. Increasing disease severity during flares and overall disease severity correlate with increased burden of S....
Administration Cutaneous Anti-Infective Agents Local Carrier State Case-Control Studies Child Child Preschool Dermatitis Atopic Drug Resistance Bacterial Female Healthy Volunteers Humans Infant Infant Newborn Male Microbial Sensitivity Tests Mutation Nasal Mucosa Peptide Elongation Factor G Severity of Illness Index Skin Staphylococcal Skin Infections Staphylococcus aureus
Personality and Psychological Predictors of Instagram Personalized Ad Avoidance
The purpose of this paper is to apply the meta-theoretical model of motivation and personality (3M) of Mowen to study consumers' ad avoidance in the context of online personalized advertisements on Instagram. The current study...
Published by: IGI Global Scientific Publishing
Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD.
Carol A Colton, Ryan T Mott, Hayley Sharpe, Qing Xu, William E Van Nostrand, Michael P Vitek
Aug 10, 2017
BACKGROUND: Microglia are associated with neuritic plaques in Alzheimer disease (AD) and serve as a primary component of the innate immune response in the brain. Neuritic plaques are fibrous deposits composed of the amyloid...
Increased Seroprevalence and Improved Antibody Responses Following Third Primary SARS-CoV-2 Immunisation
Adrian M Shields, Sian E Faustini, Harriet J Hill, Saly Al-Taei, Chloe Tanner, Fiona Ashford, Sarita Workman, Fernando Moreira, Nisha Verma, Hollie Wagg, Gail Heritage, Naomi Campton, Zania Stamataki, Mark T Drayson, Paul Klenerman, James ED Thaventhiran, Shuayb Elkhalifa, Sarah Goddard, Sarah Johnston, Aarnoud Huissoon, Claire Bethune, Suzanne Elcombe, David M Lowe, Smita Y Patel, Sinisa Savic, Alex G Richter, Siobhan O Burns, COV-AD consortium
Jun 16, 2022
BACKGROUND: Patients with primary and secondary antibody deficiency are vulnerable to COVID-19 and demonstrate diminished responses following two-dose SARS-CoV-2 vaccine schedules. Third primary vaccinations have been deployed...
DOMINO-AD protocol
Rob Jones, Bart Sheehan, Patrick Phillips, Ed Juszczak, Jessica Adams, Ashley Baldwin, Clive Ballard, Sube Banerjee, Bob Barber, Peter Bentham, Richard Brown, Alistair Burns, Tom Dening, David Findlay, Richard Gray, Mary Griffin, Clive Holmes, Alan Hughes, Robin Jacoby, Tony Johnson, Roy Jones, Martin Knapp, James Lindesay, Ian McKeith, Rupert McShane, Ajay Macharouthu, John O'Brien, Caroline Onions, Peter Passmore, James Raftery, Craig Ritchie, Rob Howard, DOMINO-AD team
Jun 16, 2011
SARS-CoV-2 Vaccine Responses in Individuals with Antibody Deficiency
Adrian M Shields, Sian E Faustini, Harriet J Hill, Saly Al-Taei, Chloe Tanner, Fiona Ashford, Sarita Workman, Fernando Moreira, Nisha Verma, Hollie Wagg, Gail Heritage, Naomi Campton, Zania Stamataki, Paul Klenerman, James ED Thaventhiran, Sarah Goddard, Sarah Johnston, Aarnoud Huissoon, Claire Bethune, Suzanne Elcombe, David M Lowe, Smita Y Patel, Sinisa Savic, Siobhan O Burns, Alex G Richter, COV-AD consortium
Aug 25, 2022
BACKGROUND: Vaccination prevents severe morbidity and mortality from COVID-19 in the general population. The immunogenicity and efficacy of SARS-CoV-2 vaccines in patients with antibody deficiency is poorly understood....
A modified Cued Recall Test for detecting prodromal AD in adults with Down syndrome.
Sharon J Krinsky-McHale, Sigan Hartley, Christy Hom, Margaret Pulsifer, Isabel CH Clare, Benjamin L Handen, Ira T Lott, Nicole Schupf, Wayne Silverman, Alzheimer's Biomarker Consortium—Down Syndrome (ABC‐DS) Investigators
Oct 03, 2022
INTRODUCTION: The development of valid methods to diagnose prodromal Alzheimer's disease (AD) in adults with Down syndrome (DS) is one of the many goals of the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS). METHODS...
Impact of Mobile Ad Wearout on Consumer Irritation, Perceived Intrusiveness, Engagement, and Loyalty
Mobile and smart devices provide a platform for firms/brands to communicate directly with past, present, or potential consumers (via online pop-ups, sponsored ads, ads on social media messengers, timelines, walls, etc.)....
Published by: IGI Global Scientific Publishing
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D Prins, Alina Solomon, Brian D Tom, Henrik Zetterberg, Marissa Zwan, Craig W Ritchie, Philip Scheltens, Gerald Luscan, Anthony J Brookes, Pieter Jelle Visser
Feb 07, 2020
BACKGROUND:Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD pathology in...
Amyloid Recruitment engagement Registries Secondary prevention trials Prescreening Trial-ready cohort
Published by: Alzheimer's research & therapy
Impact of Labeled Glasses in a Bar Laboratory Setting
AIMS: Information provided on glass labels may be an effective method to reduce alcohol consumption. The aim of this study was to assess the impact of glass labels conveying unit information and a health warning in reducing ad...
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D Prins, Alina Solomon, Brian D Tom, Henrik Zetterberg, Marissa Zwan, Craig W Ritchie, Philip Scheltens, Gerald Luscan, Anthony J Brookes, Pieter Jelle Visser, IMI-EPAD collaborators
Jan 20, 2020
BACKGROUND: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD pathology in...
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D. Prins, Alina Solomon, Brian D. Tom, Henrik Zetterberg, Marissa Zwan, Craig W. Ritchie, Philip Scheltens, Gerald Luscan, Anthony J. Brookes, Pieter Jelle Visser
Jun 06, 2020
Abstract: Background: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD...
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D. Prins, Alina Solomon, Brian D. Tom, Henrik Zetterberg, Marissa Zwan, Craig W. Ritchie, Philip Scheltens, Gerald Luscan, Anthony J. Brookes, Pieter Jelle Visser
Jan 05, 2021
Abstract: Background: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD...
Prospective longitudinal evaluation of cytokines in mild cognitive impairment due to AD and Lewy body disease.
Alan J Thomas, Calum A Hamilton, Paul C Donaghy, Carmen Martin-Ruiz, Chris M Morris, Nicola Barnett, Kirsty Olsen, John-Paul Taylor, John T O'Brien
Jun 18, 2020
OBJECTIVES: We conducted a prospective longitudinal study of plasma cytokines during the Mild Cognitive Impairment (MCI) stage of Lewy body disease and Alzheimer's disease, hypothesizing that cytokine levels would decrease over...
Maya Pottery Production at Nakum, Guatemala, during the Protoclassic Period (100/50 BC – AD 300/350)
This study investigates the Protoclassic ceramic production at Nakum, Guatemala, using it as a proxy to explore the nature of the transition from the Preclassic to Classic period (100/50 BC – AD 300/350) in Central Maya...
Original Article Original Articles ceramic analysis petrography craft organisation Guatemala Maya archaeology Protoclassic period
Published by: Archaeometry
Transcriptional, behavioural and biochemical profiling in the 3xTg-AD mouse model reveals a specific signature of amyloid deposition and functional decline in Alzheimer’s disease
Wencheng Yin, Navei Cerda Hernandez, Atahualpa Castillo Morales, Mayra Ruiz Tejada Segura, Jimena Monzón Sandoval, Perla Moreno Castillo, Rodrigo Perez Ortega, Federico Bermudez Rattoni, Araxi Urrutia, Humberto Gutierrez
Dec 15, 2020
Alzheimer’s disease (AD)-related degenerative decline is associated to the presence of amyloid beta (Aβ) plaque lesions and neuro fibrillary tangles (NFT). However, the precise molecular mechanisms linking Aβ deposition and...
Transcriptional, behavioural and biochemical profiling in the 3xTg-AD mouse model reveals a specific signature of amyloid deposition and functional decline in Alzheimer’s disease
Wencheng Yin, Navei Cerda Hernandez, Atahualpa Castillo Morales, Mayra Ruiz Tejada Segura, Jimena Monzón Sandoval, Perla Moreno Castillo, Rodrigo Perez Ortega, Federico Bermudez Rattoni, Araxi Urrutia, Humberto Gutierrez
Dec 15, 2020
Alzheimer’s disease (AD)-related degenerative decline is associated to the presence of amyloid beta (Aβ) plaque lesions and neuro fibrillary tangles (NFT). However, the precise molecular mechanisms linking Aβ deposition and...
Towards a Formal Validation of a Hybrid Multi-Agent Routing Protocol for Ad hoc Networks
In the authors' previous papers, a new ant routing protocol for ad-hoc networks inspired from ant colony optimization was presented. They introduced a new approach that decreases both node energy consumption and routing overhead...
Published by: IGI Global Scientific Publishing
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Psychological research is increasingly moving online, where web-based studies allow for data collection at scale. Behavioural researchers are well supported by existing tools for participant recruitment, and for building and...
Published by: Behavior research methods
No Impact of Calorie or Unit Information on Ad Libitum Alcohol Consumption.
Olivia M Maynard, Tess Langfield, Angela S Attwood, Emily Allen, Imogen Drew, Alex Votier, Marcus R Munafò
Jul 27, 2020
AIMS: To investigate the impact of unit and calorie information on drinking behaviour in an ad libitum taste test paradigm. METHODS: In this experimental human laboratory study, participants were randomized to one of four...
Carbohydrate-rich breakfast attenuates glycaemic, insulinaemic and ghrelin response to<i> ad libitum</i> lunch relative to morning fasting in lean adults
Enhad A. Chowdhury, Judith D. Richardson, Kostas Tsintzas, Dylan Thompson, James A. Betts
Jul 01, 2015
Breakfast omission is associated with obesity and cardiovascular disease/diabetes, but the acute effects of extended morning fasting upon subsequent energy intake and metabolic/hormonal responses have received less attention. In...
Over and under
Drawing on fieldwork in three primary schools in East Cambridgeshire, UK, this paper explores children's relationship with the places where they live, and the ways in which those relationships are mediated by play, exploration...
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