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Results: 252
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India
Jitendra PS Sawhney, Veerappa A Kothiwale, Vikas Bisne, Rajashekhar Durgaprasad, Praveen Jadhav, Manoj Chopda, Velam Vanajakshamma, Ramdhan Meena, Govindan Vijayaraghavan, Kamaldeep Chawla, Jagan Allu, Karen S Pieper, A John Camm, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 18, 2020
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics...
Stroke prevention in patients from Latin American countries with non-valvular atrial fibrillation
Carlos Jerjes-Sanchez, Ramon Corbalan, Antonio CP Barretto, Hector L Luciardi, Jagan Allu, Laura Illingworth, Karen S Pieper, Gloria Kayani, GARFIELD-AF Investigators
Mar 18, 2020
BACKGROUND: Atrial fibrillation (AF) is an important preventable cause of stroke. Anticoagulation (AC) therapy can reduce this risk. However, prescribing patterns and outcomes in patients with non-valvular AF (NVAF) from Latin...
Latin American antithrombotic treatment Atrial fibrillation outcomes Aged Anticoagulants Atrial fibrillation Drug Prescriptions Drug Utilization Female Hemorrhage Humans Male Mexico Middle Aged Practice Patterns Physicians' Prospective Studies Registries Retrospective Studies Risk Factors South America stroke Treatment Outcome
Management and 1-Year Outcomes of Patients With Newly Diagnosed Atrial Fibrillation and Chronic Kidney Disease
Shinya Goto, Pantep Angchaisuksiri, Jean-Pierre Bassand, A John Camm, Helena Dominguez, Laura Illingworth, Harry Gibbs, Samuel Z Goldhaber, Shinichi Goto, Zhi-Cheng Jing, Sylvia Haas, Gloria Kayani, Yukihiro Koretsune, Toon Wei Lim, Seil Oh, Jitendra PS Sawhney, Alexander GG Turpie, Martin van Eickels, Freek WA Verheugt, Ajay K Kakkar, GARFIELD‐AF Investigators
Jul 11, 2019
Background Using data from the GARFIELD - AF (Global Anticoagulant Registry in the FIELD -Atrial Fibrillation), we evaluated the impact of chronic kidney disease ( CKD ) stage on clinical outcomes in patients with newly...
GARFIELD‐AF registry Atrial fibrillation chronic kidney disease outcomes research Registry Administration Oral Aged Aged 80 and over Anticoagulants Asia Atrial fibrillation Female Follow-Up Studies Humans Incidence Male Middle Aged Prognosis Prospective Studies Registries Renal Insufficiency Chronic Risk Assessment Risk Factors Severity of Illness Index stroke Survival Rate Time Factors
Screening for Atrial Fibrillation
Ben Freedman, John Camm, Hugh Calkins, Jeffrey S Healey, Mårten Rosenqvist, Jiguang Wang, Christine M Albert, Craig S Anderson, Sotiris Antoniou, Emelia J Benjamin, Giuseppe Boriani, Johannes Brachmann, Axel Brandes, Tze-Fan Chao, David Conen, Johan Engdahl, Laurent Fauchier, David A Fitzmaurice, Leif Friberg, Bernard J Gersh, David J Gladstone, Taya V Glotzer, Kylie Gwynne, Graeme J Hankey, Joseph Harbison, Graham S Hillis, Mellanie T Hills, Hooman Kamel, Paulus Kirchhof, Peter R Kowey, Derk Krieger, Vivian WY Lee, Lars-Åke Levin, Gregory YH Lip, Trudie Lobban, Nicole Lowres, Georges H Mairesse, Carlos Martinez, Lis Neubeck, Jessica Orchard, Jonathan P Piccini, Katrina Poppe, Tatjana S Potpara, Helmut Puererfellner, Michiel Rienstra, Roopinder K Sandhu, Renate B Schnabel, Chung-Wah Siu, Steven Steinhubl, Jesper H Svendsen, Emma Svennberg, Sakis Themistoclakis, Robert G Tieleman, Mintu P Turakhia, Arnljot Tveit, Steven B Uittenbogaart, Isabelle C Van Gelder, Atul Verma, Rolf Wachter, Bryan P Yan, AF-Screen Collaborators
May 03, 2018
Approximately 10% of ischemic strokes are associated with atrial fibrillation (AF) first diagnosed at the time of stroke. Detecting asymptomatic AF would provide an opportunity to prevent these strokes by instituting appropriate...
Risk factors for death, stroke, and bleeding in 28,628 patients from the GARFIELD-AF registry
Jean-Pierre Bassand, Gabriele Accetta, Wael Al Mahmeed, Ramon Corbalan, John Eikelboom, David A Fitzmaurice, Keith AA Fox, Haiyan Gao, Samuel Z Goldhaber, Shinya Goto, Sylvia Haas, Gloria Kayani, Karen Pieper, Alexander GG Turpie, Martin van Eickels, Freek WA Verheugt, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 30, 2020
BACKGROUND: The factors influencing three major outcomes-death, stroke/systemic embolism (SE), and major bleeding-have not been investigated in a large international cohort of unselected patients with newly diagnosed atrial...
Two-year outcomes of patients with newly diagnosed atrial fibrillation
Jean-Pierre Bassand, Gabriele Accetta, Alan John Camm, Frank Cools, David A Fitzmaurice, Keith AA Fox, Samuel Z Goldhaber, Shinya Goto, Sylvia Haas, Werner Hacke, Gloria Kayani, Lorenzo G Mantovani, Frank Misselwitz, Hugo Ten Cate, Alexander GG Turpie, Freek WA Verheugt, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 18, 2020
AIMS: The relationship between outcomes and time after diagnosis for patients with non-valvular atrial fibrillation (NVAF) is poorly defined, especially beyond the first year. METHODS AND RESULTS: GARFIELD-AF is an ongoing...
Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation
Sylvia Haas, Hugo Ten Cate, Gabriele Accetta, Pantep Angchaisuksiri, Jean-Pierre Bassand, A John Camm, Ramon Corbalan, Harald Darius, David A Fitzmaurice, Samuel Z Goldhaber, Shinya Goto, Barry Jacobson, Gloria Kayani, Lorenzo G Mantovani, Frank Misselwitz, Karen Pieper, Sebastian M Schellong, Janina Stepinska, Alexander GG Turpie, Martin van Eickels, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 18, 2020
AIMS: Vitamin K antagonists (VKAs) need to be individually dosed. International guidelines recommend a target range of international normalised ratio (INR) of 2.0-3.0 for stroke prevention in atrial fibrillation (AF). We...
Improved risk stratification of patients with atrial fibrillation
Keith AA Fox, Joseph E Lucas, Karen S Pieper, Jean-Pierre Bassand, A John Camm, David A Fitzmaurice, Samuel Z Goldhaber, Shinya Goto, Sylvia Haas, Werner Hacke, Gloria Kayani, Ali Oto, Lorenzo G Mantovani, Frank Misselwitz, Jonathan P Piccini, Alexander GG Turpie, Freek WA Verheugt, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 18, 2020
OBJECTIVES: To provide an accurate, web-based tool for stratifying patients with atrial fibrillation to facilitate decisions on the potential benefits/risks of anticoagulation, based on mortality, stroke and bleeding risks....
CHA2DS2-VASc Atrial fibrillation Risk stratification Aged Aged 80 and over Anticoagulants Atrial fibrillation Cause of Death Female Hemorrhage Humans Internationality Kaplan-Meier Estimate Male Middle Aged Prospective Studies ROC Curve Registries Regression Analysis Risk Assessment Risk Factors Severity of Illness Index stroke Time Factors
Impact of gender on event rates at 1 year in patients with newly diagnosed non-valvular atrial fibrillation
A John Camm, Gabriele Accetta, Wael Al Mahmeed, Giuseppe Ambrosio, Samuel Z Goldhaber, Sylvia Haas, Petr Jansky, Gloria Kayani, Frank Misselwitz, Seil Oh, Ali Oto, Pekka Raatikainen, Jan Steffel, Martin van Eickels, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 18, 2020
OBJECTIVES: Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) explored the impact of gender, risk factors and anticoagulant (AC) treatment on 1-year outcomes in patients with non-valvular atrial...
Whole-body magnetic resonance angiography.
Vascular disease, whether it be atherosclerosis, inflammatory, or hereditary vasculitide, is a systemic disorder with disease in one territory predictive of disease in another. Despite this, current approaches focus on...
Evolving antithrombotic treatment patterns for patients with newly diagnosed atrial fibrillation.
A John Camm, Gabriele Accetta, Giuseppe Ambrosio, Dan Atar, Jean-Pierre Bassand, Eivind Berge, Frank Cools, David A Fitzmaurice, Samuel Z Goldhaber, Shinya Goto, Sylvia Haas, Gloria Kayani, Yukihiro Koretsune, Lorenzo G Mantovani, Frank Misselwitz, Seil Oh, Alexander GG Turpie, Freek WA Verheugt, Ajay K Kakkar, GARFIELD-AF Investigators
Mar 30, 2020
OBJECTIVE: We studied evolving antithrombotic therapy patterns in patients with newly diagnosed non-valvular atrial fibrillation (AF) and ≥1 additional stroke risk factor between 2010 and 2015. METHODS: 39 670 patients were...
stroke Administration Oral Age Factors Aged Aged 80 and over Atrial fibrillation Comorbidity Female Fibrinolytic Agents Guideline Adherence Humans Male Middle Aged Practice Guidelines as Topic Practice Patterns Physicians' Prospective Studies Registries Risk Assessment Risk Factors Sex Factors stroke Time Factors Treatment Outcome
Naturally Occurring Calanolides
Lutfun Nahar, Anupam Das Talukdar, Deepa Nath, Sushmita Nath, Aman Mehan, Fyaz MD Ismail, Satyajit D Sarker
Oct 29, 2020
Calanolides are tetracyclic 4-substituted dipyranocoumarins. Calanolide A, isolated from the leaves and twigs of Calophyllum lanigerum var. austrocoriaceum (Whitmore) P. F. Stevens, is the first member of this group of compounds...
Sepsis-driven atrial fibrillation and ischaemic stroke. Is there enough evidence to recommend anticoagulation?
Isuru Induruwa, Eleanor Hennebry, James Hennebry, Mrinal Thakur, Elizabeth A Warburton, Kayvan Khadjooi
Oct 19, 2021
Sepsis can lead to cardiac arrhythmias, of which the most common is atrial fibrillation (AF). Sepsis is associated with up to a six-fold higher risk of developing AF, where it occurs most commonly in the first 3 days of hospital...
Sleep Disordered Breathing, Obesity and Atrial Fibrillation
Maddalena Ardissino, Rohin K Reddy, Eric Slob, Kiran HK Patel, David K Ryan, Dipender Gill, Fu Siong Ng
Jan 10, 2022
It remains unclear whether the association between obstructive sleep apnoea (OSA), a form of sleep-disordered breathing (SDB), and atrial fibrillation (AF) is causal or mediated by shared co-morbidities such as obesity. Existing...
A meta-analysis of extended ECG monitoring in detection of atrial fibrillation in patients with cryptogenic stroke.
Haowen Jiang, Shyn Yi Tan, Jeremy King Wang, Jiaqi Li, Tian Ming Tu, Vern Hsen Tan, Colin Yeo
Oct 30, 2022
OBJECTIVE: The aim of this systematic review is to evaluate the various modalities available for extended ECG monitoring in the detection of atrial fibrillation (AF) following a cryptogenic stroke. METHODS: MEDLINE (Ovid)...
A randomised controlled trial and cost effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in the over 65s
Dawn Swancutt, Richard Hobbs, David Fitzmaurice, Jonathan Mant, Ellen Murray, Sue Jowett, James Raftery, Stirling Bryan, Michael Davies, Gregory Lip
May 03, 2018
BACKGROUND: Atrial fibrillation (AF) has been recognised as an important independent risk factor for thromboembolic disease, particularly stroke for which it provides a five-fold increase in risk. This study aimed to determine...
Body mass index and body fat distribution and new-onset atrial fibrillation
J Neefs, SM Boekholdt, K-T Khaw, R Luben, R Pfister, NJ Wareham, ER Meulendijks, P Sanders, JR de Groot
Sep 06, 2019
BACKGROUND AND AIM: Obesity is a recognized risk factor for new-onset atrial fibrillation (AF). The association between body fat distribution, which is measured by body mass index (BMI) and waist-hip ratio (WHR), its changes...
Temporal trends in incidence of atrial fibrillation in primary care records
Objectives: Atrial fibrillation (AF) is a heart condition associated with a fivefold increased risk of stroke. The condition can be detected in primary care and treatment can greatly reduce the risk of stroke. In recent years, a...
Influence of delayed immune reactions on human epidermal keratinocytes
The epidermal changes that occur in human cutaneous immune responses have been investigated in the tuberculin reaction and in the lesions of tuberculoid and lepromatous leprosy and cutaneous leishmaniasis. In each situation...
delayed hypersensitivity epidermis Histopathology immunopathology keratinocyte lepromatous leprosy skin leishmaniasis uberculin test
Published by: Rockefeller University
Ambient Air Pollution and Acute Ischemic Stroke-Effect Modification by Atrial Fibrillation.
Benjamin Yong-Qiang Tan, Jamie Sin Ying Ho, Andrew Fu-Wah Ho, Pin Pin Pek, Aloysius Sheng-Ting Leow, Yogeswari Raju, Ching-Hui Sia, Leonard Leong-Litt Yeo, Vijay Kumar Sharma, Marcus Eng-Hock Ong, Joel Aik, Huili Zheng
Oct 24, 2022
Acute ischemic strokes (AIS) are closely linked with air pollution, and there is some evidence that traditional cardiovascular risk factors may alter the relationship between air pollution and strokes. We investigated the effect...
Screening for Atrial Fibrillation
Madhumitha Pandiaraja, James Brimicombe, Martin Cowie, Andrew Dymond, Hannah Clair Lindén, Gregory YH Lip, Jonathan Mant, Kate Williams, Peter H Charlton
Jan 07, 2021
Atrial fibrillation (AF) is a common irregular heart rhythm associated with a five-fold increase in stroke risk. It is often not recognised as it can occur intermittently and without symptoms. A promising approach to detect AF...
A rapid and robust method for single cell chromatin accessibility profiling.
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) is widely used to identify regulatory regions throughout the genome. However, very few studies have been performed at the single cell level (scATAC-seq)...
The predictive value of abnormal P-wave axis for the detection of incident atrial fibrillation
Rahul Kumar Chattopadhyay, Panagiota Anna Chousou, Trisha Mukherjee, Peter John Pugh, Vassilios S Vassiliou
Dec 08, 2022
INTRODUCTION: There is growing interest in the prediction of incident atrial fibrillation (AF). The 12-lead electrocardiogram (ECG) has been a particularly rich target for possible prediction strategies. PURPOSE: The P-wave axis...
A randomised controlled trial and cost-effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in people aged 65 and over. The SAFE study.
FDR Hobbs, DA Fitzmaurice, J Mant, E Murray, S Jowett, S Bryan, J Raftery, M Davies, G Lip
Mar 13, 2019
OBJECTIVES: To determine the most cost-effective method of screening for atrial fibrillation (AF) in the population aged 65 years and over, as well as its prevalence and incidence in this age group. Also to evaluate the relative...
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