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Effect of Alloying on the Microstructure, Phase Stability, Hardness, and Partitioning Behavior of a New Dual-Superlattice Nickel-Based Superalloy
Abstract A novel γ –γ ′–γ ″ dual-superlattice superalloy, with promising mechanical properties up to elevated...
C Rodenkirchen, AK Ackerman, PM Mignanelli, A Cliff, GJ Wise, P Breul, JO Douglas, PAJ Bagot, MP Moody, M Appleton, MP Ryan, MC Hardy, S Pedrazzini, HJ Stone
Apr 05, 2023
Topical treatment of actinic keratoses in organ transplant recipients
Zeeshaan-Ul Hasan, Ikhlaaq Ahmed, Rubeta N Matin, Victoria Homer, John T Lear, Ferina Ismail, Tristan Whitmarsh, Adele C Green, Jason Thomson, Alan Milligan, Sarah Hogan, Vanessa Van-de-Velde, Liza Mitchell-Worsford, Jonathan Kentley, Claire Gaunt, Yolande Jefferson-Hulme, Sarah J Bowden, Piers Gaunt, Keith Wheatley, Charlotte M Proby, Catherine A Harwood
Jun 14, 2022
BACKGROUND: The risk of cutaneous squamous cell carcinoma (cSCC) is significantly increased in organ transplant recipients (OTRs). Clearance of actinic keratoses (AKs) is generally regarded as a surrogate biomarker for cSCC...
Secreted Toxins From Staphylococcus aureus Strains Isolated From Keratinocyte Skin Cancers Mediate Pro-tumorigenic Inflammatory Responses in the Skin.
Annika Krueger, Julian Zaugg, Sarah Chisholm, Richard Linedale, Nancy Lachner, Siok Min Teoh, Zewen K Tuong, Samuel W Lukowski, Mark Morrison, H Peter Soyer, Philip Hugenholtz, Michelle M Hill, Ian H Frazer
Feb 08, 2022
Squamous cell carcinoma (SCC) is a common type of skin cancer that typically arises from premalignant precursor lesions named actinic keratoses (AK). Chronic inflammation is a well-known promoter of skin cancer progression. AK...
The Role of Adipocytes in the Tumor Microenvironment in Obesity-Driven Breast Cancer Progression
Sarah Ackerman
Jan 01, 0001
Obesity affects more than 1 in 3 adults in the United States and has been shown to increase the relative risk of death for women with breast cancer and to increase the risk of developing breast cancer in post-menopausal women....
Published by: Rockefeller University
Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells.
Y Lin, FM Richards, B-F Krippendorff, JL Bramhall, JA Harrington, TE Bapiro, A Robertson, D Zheleva, DI Jodrell
Feb 12, 2020
BACKGROUND: Amplification of aurora kinase A (AK-A) overrides the mitotic spindle assembly checkpoint, inducing resistance to taxanes. RNA interference targeting AK-A in human pancreatic cancer cell lines enhanced taxane...
Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage.
Zewen K Tuong, Andrew Lewandowski, Jennifer A Bridge, Jazmina LG Cruz, Miko Yamada, Duncan Lambie, Richard Lewandowski, Raymond J Steptoe, Graham R Leggatt, Fiona Simpson, Ian H Frazer, H Peter Soyer, James W Wells
Feb 03, 2020
Actinic Keratosis (AK), Intraepidermal Carcinoma (IEC), and Squamous Cell Carcinoma (SCC) are generally considered to be advancing stages of the same disease spectrum. However, while AK often regress spontaneously, and IEC often...
The Rise of Anti-immigrant Policies
Susanna Jones, Rich Furman, Melody Loya, Alissa R. Ackerman, Nalini Negi, Doug Epps, Gladys Mondragon
Jan 07, 2015
This article examines United States immigration policy in three states: Arizona, Alabama, and Indiana. All three states have varying rates of Latino immigration and a complex set of socioeconomic and cultural factors; yet...
Published by: Memorial University of Newfoundland
Does Knowledge Really Help?
Drawing on the self-determination theory, this study explored the effect of three kinds of low-carbon knowledge (LCB), including system knowledge (SK), action-related knowledge (AK), and effectiveness knowledge (EK), on college...
Published by: IGI Global Scientific Publishing
Charcot-Leyden crystal protein/galectin-10 interacts with cationic ribonucleases and is required for eosinophil granulogenesis
Milica Grozdanovic, Christine Doyle, Li Lu, Brian Maybruck, Mark Kwatia, Nethaji Thiyagarajan, Ravi Acharya, Steven Ackerman
Aug 31, 2020
Background
The human eosinophil Charcot-Leyden Crystal (CLC) protein is a member of the Galectin superfamily and is also known as Galectin-10 (Gal-10). CLC/Gal-10 forms the distinctive hexagonal bipyramidal crystals...
The human eosinophil Charcot-Leyden Crystal (CLC) protein is a member of the Galectin superfamily and is also known as Galectin-10 (Gal-10). CLC/Gal-10 forms the distinctive hexagonal bipyramidal crystals...
HSCs revive their niche after transplantation.
Simón Méndez-Ferrer
Dec 11, 2020
Golan K, Singh AK et al.1 describe how mitochondrial transfer from hematopoietic stem cells (HSCs) to bone marrow (BM) mesenchymal stem cells (MSCs) helps to regenerate the stroma and its capacity to sustain hematopoietic...
The Rise of Anti-immigrant Policies
Susanna Jones, Rich Furman, Melody Loya, Alissa R. Ackerman, Nalini Negi, Doug Epps, Gladys Mondragon
Jan 07, 2015
This article examines United States immigration policy in three states: Arizona, Alabama, and Indiana. All three states have varying rates of Latino immigration and a complex set of socioeconomic and cultural factors; yet...
undocumented immigrants criminalization of immigrants anti-immigrant legislation Arizona SB 1070 Alabama HB 56 Indiana SB 590
Published by: Memorial University of Newfoundland
Weibull recurrent neural networks for failure prognosis using histogram data
Abstract Weibull time-to-event recurrent neural networks (WTTE-RNN) is a simple and versatile prognosis algorithm that works by optimising a Weibull survival function using a recurrent neural...
Synchronisation of policy related uncertainty, financial stress and economic activity in the United States
Abstract: This study analyses the synchronisation of economic activity, financial stress and uncertainty in the United States by employing a wavelet‐based approach of cohesion. Being innovative in the choice of the...
Estrogen Receptor and Signal Transducer and Activator of Transcription 3 Expression in Equine Mammary Tumors.
Balancing scarce hospital resources during the COVID-19 pandemic using discrete-event simulation.
COVID-19 has disrupted healthcare operations and resulted in large-scale cancellations of elective surgery. Hospitals throughout the world made life-altering resource allocation decisions and prioritised the care of COVID-19...
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