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Imaging sex/gender and autism in the brain
The male preponderance in autism prevalence has brought together the disparate topics of sex/gender and autism research. Two directions of neuroimaging studies on the relationships between sex/gender and autism may inform...
A meta-analysis of sex differences in human brain structure.
Amber NV Ruigrok, Gholamreza Salimi-Khorshidi, Meng-Chuan Lai, Simon Baron-Cohen, Michael V Lombardo, Roger J Tait, John Suckling
Aug 08, 2017
The prevalence, age of onset, and symptomatology of many neuropsychiatric conditions differ between males and females. To understand the causes and consequences of sex differences it is important to establish where they occur in...
Autism and family involvement in the right to education in the EU
Robin van Kessel, Andres Roman-Urrestarazu, Amber Ruigrok, Rosemary Holt, Matt Commers, Rosa A Hoekstra, Katarzyna Czabanowska, Carol Brayne, Simon Baron-Cohen
Dec 02, 2019
Improving effect size estimation and statistical power with multi-echo fMRI and its impact on understanding the neural systems supporting mentalizing.
Michael V Lombardo, Bonnie Auyeung, Rosemary J Holt, Jack Waldman, Amber NV Ruigrok, Natasha Mooney, Edward T Bullmore, Simon Baron-Cohen, Prantik Kundu
Aug 15, 2017
Improving effect size estimation and statistical power with multi-echo fMRI and its impact on understanding the neural systems supporting mentalizing
Autism and the right to education in the EU
Monika Roleska, Andres Roman-Urrestarazu, Sarah Griffiths, Amber NV Ruigrok, Rosemary Holt, Robin van Kessel, Kathleen McColl, William Sherlaw, Carol Brayne, Kasia Czabanowska
Dec 17, 2018
INTRODUCTION: Autistic people may have different educational needs that need to be met to allow them to develop their full potential. Education and disability policies remain within the competence of EU Member States, with...
Sex-specific impact of prenatal androgens on social brain default mode subsystems.
Autism and family involvement in the right to education in the EU
Robin van Kessel, Andres Roman-Urrestarazu, Amber Ruigrok, Rosemary Holt, Matt Commers, Rosa A Hoekstra, Katarzyna Czabanowska, Carol Brayne, Simon Baron-Cohen
Jan 12, 2020
Introduction:In recent years, the universal right to education has been emphasised by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this paper, we mapped policies...
Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort.
Novika Purnama Sari, Pauline W Jansen, Laura ME Blanken, Amber NV Ruigrok, Peter Prinzie, Henning Tiemeier, Simon Baron-Cohen, Marinus H van IJzendoorn, Tonya White
Jul 16, 2022
BACKGROUND: Many empirical studies suggest that higher maternal age increases the likelihood of having an autistic child. However, little is known about factors that may explain this relationship or if higher maternal age is...
Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort.
Enhancement of indirect functional connections with shortest path length in the adult autistic brain.
Xiaonan Guo, Tiago Simas, Meng-Chuan Lai, Michael V Lombardo, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, Simon Baron-Cohen, Huafu Chen, John Suckling, MRC AIMS Consortium
Sep 16, 2019
Autism is a neurodevelopmental condition characterized by atypical brain functional organization. Here we investigated the intrinsic indirect (semi-metric) connectivity of the functional connectome associated with autism....
Autism and the right to education in the EU
Robin van Kessel, Sebastian Walsh, Amber N. V. Ruigrok, Rosemary Holt, Anneli Yliherva, Eija Kärnä, Irma Moilanen, Eva Hjörne, Shruti Taneja Johansson, Diana Schendel, Lennart Pedersen, Meta Jørgensen, Carol Brayne, Simon Baron-Cohen, Andres Roman-Urrestarazu
Dec 10, 2020
Abstract: Introduction: The universal right to education for people with disabilities has been highlighted by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this...
The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism.
Florina Uzefovsky, Richard AI Bethlehem, Simone Shamay-Tsoory, Amber Ruigrok, Rosemary Holt, Michael Spencer, Lindsay Chura, Varun Warrier, Bhismadev Chakrabarti, Ed Bullmore, John Suckling, Dorothea Floris, Simon Baron-Cohen
May 01, 2019
BACKGROUND: Autism is a highly varied and heritable neurodevelopmental condition, and common variants explain approximately 50% of the genetic variance of autism. One of the genes implicated in autism is the oxytocin receptor...
Neural self-representation in autistic women and association with 'compensatory camouflaging'.
Meng-Chuan Lai, Michael V Lombardo, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, John Suckling, Bonnie Auyeung, Francesca Happé, Peter Szatmari, Simon Baron-Cohen, MRC AIMS Consortium
Dec 03, 2018
Prior work has revealed sex/gender-dependent autistic characteristics across behavioural and neural/biological domains. It remains unclear whether and how neural sex/gender differences are related to behavioural sex/gender...
Adult autism camouflaging compensation functional magnetic resonance imaging Gender Heterogeneity Mentalizing Self sex Adolescent Adult Autistic Disorder Brain Case-Control Studies Female Functional Neuroimaging Humans Magnetic Resonance Imaging Male mentalization Middle Aged Self Concept Sex Factors Social Behavior Young Adult
Autism and family involvement in the right to education in the EU
Robin van Kessel, Andres Roman-Urrestarazu, Amber Ruigrok, Rosemary Holt, Matt Commers, Rosa A. Hoekstra, Katarzyna Czabanowska, Carol Brayne, Simon Baron-Cohen
Dec 08, 2020
Abstract: Introduction: In recent years, the universal right to education has been emphasised by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this paper, we mapped...
Medical symptoms and conditions in autistic women.
Tslil Simantov, Alexa Pohl, Alexandros Tsompanidis, Elizabeth Weir, Michael V Lombardo, Amber Ruigrok, Paula Smith, Carrie Allison, Simon Baron-Cohen, Florina Uzefovsky
Feb 04, 2022
Autism and the right to education in the EU
Robin van Kessel, Sebastian Walsh, Amber N V Ruigrok, Rosemary Holt, Anneli Yliherva, Eija Kärnä, Irma Moilanen, Eva Hjörne, Shruti Taneja Johansson, Diana Schendel, Lennart Pedersen, Meta Jørgensen, Carol Brayne, Simon Baron-Cohen, Andres Roman-Urrestarazu
Jan 29, 2020
Introduction:The universal right to education for people with disabilities has been highlighted by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this paper, we mapped...
Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.
Titia G Meijer, Luan Nguyen, Arne Van Hoeck, Anieta M Sieuwerts, Nicole S Verkaik, Marjolijn M Ladan, Kirsten Ruigrok-Ritstier, Carolien HM van Deurzen, Harmen JG van de Werken, Esther H Lips, Sabine C Linn, Yasin Memari, Helen Davies, Serena Nik-Zainal, Roland Kanaar, John WM Martens, Edwin Cuppen, Agnes Jager, Dik C van Gent
Jun 29, 2022
Germline BRCA1/2 mutation status is predictive for response to Poly-[ADP-Ribose]-Polymerase (PARP) inhibitors in breast cancer (BC) patients. However, non-germline BRCA1/2 mutated and homologous recombination repair deficient...
Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.
Titia G Meijer, Luan Nguyen, Arne Van Hoeck, Anieta M Sieuwerts, Nicole S Verkaik, Marjolijn M Ladan, Kirsten Ruigrok-Ritstier, Carolien HM van Deurzen, Harmen JG van de Werken, Esther H Lips, Sabine C Linn, Yasin Memari, Helen Davies, Serena Nik-Zainal, Roland Kanaar, John WM Martens, Edwin Cuppen, Agnes Jager, Dik C van Gent
Jul 07, 2022
Germline BRCA1/2 mutation status is predictive for response to Poly-[ADP-Ribose]-Polymerase (PARP) inhibitors in breast cancer (BC) patients. However, non-germline BRCA1/2 mutated and homologous recombination repair deficient...
COVID-19 health and social care access for autistic people
Bethany Oakley, Julian Tillmann, Amber Ruigrok, Aurélie Baranger, Christian Takow, Tony Charman, Emily Jones, James Cusack, Mary Doherty, Pierre Violland, Agnieszka Wroczyńska, Emily Simonoff, Jan K Buitelaar, Louise Gallagher, Declan GM Murphy, AIMS-2-TRIALS ECRAN & the AIMS-2-TRIALS Consortium
Jun 18, 2021
BACKGROUND: The global COVID-19 pandemic has had an unprecedented impact on European health and social care systems, with demands on testing, hospital and intensive care capacity exceeding available resources in many regions....
Unsupervised data-driven stratification of mentalizing heterogeneity in autism
Unsupervised data-driven stratification of mentalizing heterogeneity in autism.
Michael V Lombardo, Meng-Chuan Lai, Bonnie Auyeung, Rosemary J Holt, Carrie Allison, Paula Smith, Bhismadev Chakrabarti, Amber NV Ruigrok, John Suckling, Edward T Bullmore, MRC AIMS Consortium, Christine Ecker, Michael C Craig, Declan GM Murphy, Francesca Happé, Simon Baron-Cohen
Aug 16, 2017
In Vivo Evidence of Reduced Integrity of the Gray-White Matter Boundary in Autism Spectrum Disorder.
Derek Sayre Andrews, Thomas A Avino, Maria Gudbrandsen, Eileen Daly, Andre Marquand, Clodagh M Murphy, Meng-Chuan Lai, Michael V Lombardo, Amber NV Ruigrok, Steven C Williams, Edward T Bullmore, The Mrc Aims Consortium, John Suckling, Simon Baron-Cohen, Michael C Craig, Declan GM Murphy, Christine Ecker
Aug 17, 2017
Atypical cortical organization and reduced integrity of the gray-white matter boundary have been reported by postmortem studies in individuals with autism spectrum disorder (ASD). However, there are no in vivo studies that...
Association Between the Probability of Autism Spectrum Disorder and Normative Sex-Related Phenotypic Diversity in Brain Structure.
Christine Ecker, Derek S Andrews, Christina M Gudbrandsen, Andre F Marquand, Cedric E Ginestet, Eileen M Daly, Clodagh M Murphy, Meng-Chuan Lai, Michael V Lombardo, Amber NV Ruigrok, Edward T Bullmore, John Suckling, Steven Cr Williams, Simon Baron-Cohen, Michael C Craig, Declan GM Murphy, Medical Research Council Autism Imaging Multicentre Study (MRC AIMS) Consortium
Aug 16, 2017
IMPORTANCE: Autism spectrum disorder (ASD) is 2 to 5 times more common in male individuals than in female individuals. While the male preponderant prevalence of ASD might partially be explained by sex differences in clinical...
Medical Research Council Autism Imaging Multicentre Study (MRC AIMS) Consortium Cerebral Cortex Humans Image Interpretation Computer-Assisted Magnetic Resonance Imaging Image Enhancement Multivariate Analysis Models Statistical Risk Factors Case-Control Studies Cross-Sectional Studies Sex Characteristics Phenotype Reference Values Adolescent Adult Female Male Young Adult white matter Gray Matter Autism spectrum disorder
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