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Interview with Dora Jones - OH 327
Dora Jones
Jan 01, 0001
In her June 1984 interview with Michael Cooke, Dora Jones detailed her work with DHEC's sickle cell program. Jones discussed the misconceptions of sickle cell within South Carolina communities, the role of community groups, and...
sickle cell anemia Department of Health and Environmental Control (DHEC) Sickle cell trait Crippled Children's Division Oral History
Published by: Winthrop University
Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis
Christian Merle, Wenzel Waldstein, Jennifer S Gregory, Simon R Goodyear, Richard M Aspden, Peter R Aldinger, David W Murray, Harinderjit S Gill
Jan 01, 0001
The objectives of the present study were to determine (1) whether differences in the radiographic appearance of the of the proximal femoral canal exist on corresponding AP pelvis and AP hip radiographs, and (2) whether...
AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A.
Alexandra K Davies, Daniel N Itzhak, James R Edgar, Tara L Archuleta, Jennifer Hirst, Lauren P Jackson, Margaret S Robinson, Georg HH Borner
Dec 13, 2018
Adaptor protein 4 (AP-4) is an ancient membrane trafficking complex, whose function has largely remained elusive. In humans, AP-4 deficiency causes a severe neurological disorder of unknown aetiology. We apply unbiased proteomic...
Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells.
In polarized epithelial cells, newly synthesized membrane proteins are delivered on specific pathways to either the apical or basolateral domains, depending on the sorting motifs present in these proteins. Because myosin VI has...
Adaptor Protein Complex 1 Amino Acid Motifs Animals Cell Cycle Proteins Cell Line Cell Polarity Dogs Endosomes Humans Membrane Glycoproteins Membrane Transport Proteins Mutagenesis Site-Directed Myosin Heavy Chains Protein Isoforms Protein Transport Transcription Factor TFIIIA Viral Envelope Proteins
Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis
Christian Merle, Wenzel Waldstein, Jennifer S Gregory, Simon R Goodyear, Richard M Aspden, Peter R Aldinger, David W Murray, Harinderjit S Gill
Jan 01, 0001
The objectives of the present study were to determine (1) whether differences in the radiographic appearance of the of the proximal femoral canal exist on corresponding AP pelvis and AP hip radiographs, and (2) whether...
Boyd Jones Wins Lifetime Achievement Award from Campus Programming Association
Winthrop University
Jan 01, 0001
The Association for the Promotion of Campus Activities gave Jones the Lifetime Achievement Award. Jones has worked at Winthrop for more than 20 years.
Published by: Winthrop University
The Lennard-Jones potential
The Lennard-Jones 12-6 potential (LJ) is arguably the most widely used pair potential in molecular simulations. In fact, it is so popular that the question is rarely asked whether it is fit for purpose. In this paper, we argue...
Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.
Jennifer Hirst, Georg HH Borner, James Edgar, Marco Y Hein, Matthias Mann, Frank Buchholz, Robin Antrobus, Margaret S Robinson
Feb 13, 2019
The AP-5 complex is a recently identified but evolutionarily ancient member of the family of heterotetrameric adaptor proteins (AP complexes). It is associated with two proteins that are mutated in patients with hereditary...
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex.
Adaptor protein complex 5 (AP-5) and its partners, SPG11 and SPG15, are recruited onto late endosomes and lysosomes. Here we show that recruitment of AP-5/SPG11/SPG15 is enhanced in starved cells and occurs by coincidence...
Adaptor Proteins Vesicular Transport Carrier Proteins Endosomes HEK293 Cells HeLa Cells Humans Lysosomes Mechanistic Target of Rapamycin Complex 1 Models Biological Monomeric GTP-Binding Proteins Multiprotein Complexes Nucleotides Phosphatidylinositol 3-Kinases Phosphatidylinositol Phosphates Protein Domains Proteins
Boyd Jones of DSU Honored By National Association of Campus Activities
Winthrop University
Jan 01, 0001
Jones, who has worked at Winthrop for 20 years and also served 11 years at the University of Tulsa, oversees Winthrop's DiGiorgio Student Union (DSU) which provides quality on-campus programming to educate and entertain members...
Published by: Winthrop University
Black Imagination Through Tara Betts and Saeed Jones
Miara Truog Sebouhian
Jan 01, 0001
This project discusses Black imagination in How We Fight for Our Lives by Saeed Jones and Storm Writes to Black Panther by Tara Betts.
Saeed Jones Black Imagination Tara Betts Black Panther African American Studies Digital Humanities Literature in English, North America, Ethnic and Cultural Minority
Published by: Ursinus College
Prediction of three-dimensional femoral offset from AP pelvis radiographs in primary hip osteoarthritis
C Merle, W Waldstein, Elise Pegg, M R Streit, T Gotterbarm, P R Aldinger, D W Murray, H S Gill
Aug 01, 2013
BACKGROUND: In pre-operative planning for total hip arthroplasty (THA), femoral offset (FO) is frequently underestimated on AP pelvis radiographs as a result of inaccurate patient positioning, imprecise magnification, and...
Avis Jones-DeWeever to Talk About Black Women in the Great Recession
Winthrop University
Jan 01, 0001
Jones-DeWeever, who will speak at 7 p.m. in Plowden Auditorium, will discuss "We've Come Too Far to Turn Back Now: Black Women in the Wake of the Great Recession." An accomplished scholar, writer and public speaker...
Published by: Winthrop University
Jones Chosen to Lead University College for Winthrop
Winthrop University
Jan 01, 0001
Winthrop University officials have tapped Gloria Godfrey Jones, chair of the Department of English, as the new dean of University College.
Published by: Winthrop University
Marshall Jones Traveling to Philippines as Part of U.S. Department of State's Education Outreach Initiative
Winthrop University
Jan 01, 0001
Education Professor Marshall Jones will travel to the Philippines as part of one of the U.S. Department of State's education outreach initiatives. Jones will be working with educators on the use of technology in teaching and...
Published by: Winthrop University
Prediction of three-dimensional femoral offset from AP pelvis radiographs in primary hip osteoarthritis
C Merle, W Waldstein, Elise Pegg, M R Streit, T Gotterbarm, P R Aldinger, D W Murray, H S Gill
Aug 01, 2013
BACKGROUND: In pre-operative planning for total hip arthroplasty (THA), femoral offset (FO) is frequently underestimated on AP pelvis radiographs as a result of inaccurate patient positioning, imprecise magnification, and...
The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Nikolai Schleussner, Olaf Merkel, Mariantonia Costanza, Huan-Chang Liang, Franziska Hummel, Chiara Romagnani, Pawel Durek, Ioannis Anagnostopoulos, Michael Hummel, Korinna Jöhrens, Antonia Niedobitek, Patrick R Griffin, Roberto Piva, Henrike L Sczakiel, Wilhelm Woessmann, Christine Damm-Welk, Christian Hinze, Dagmar Stoiber, Bernd Gillissen, Suzanne D Turner, Eva Kaergel, Linda von Hoff, Michael Grau, Georg Lenz, Bernd Dörken, Claus Scheidereit, Lukas Kenner, Martin Janz, Stephan Mathas
Mar 20, 2018
Transcription factor AP-1 is constitutively activated and IRF4 drives growth and survival in ALK+ and ALK- anaplastic large cell lymphoma (ALCL). Here we demonstrate high-level BATF and BATF3 expression in ALCL. Both BATFs bind...
Basic-Leucine Zipper Transcription Factors Binding Sites CRISPR-Cas Systems Carrier Proteins Cell Death Cell Line Tumor Cell Survival Cytokines Gene Editing Gene Expression Regulation Neoplastic Gene Knockdown Techniques Humans Lymphoma Large-Cell Anaplastic Protein Binding Protein Kinase Inhibitors RNA Small Interfering T-Lymphocyte Subsets Th17 Cells Transcription Factor AP-1 Transcriptome
A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers.
Shanna L Bowman, Linh Le, Yueyao Zhu, Dawn C Harper, Anand Sitaram, Alexander C Theos, Elena V Sviderskaya, Dorothy C Bennett, Graça Raposo-Benedetti, David J Owen, Megan K Dennis, Michael S Marks
Apr 12, 2021
Membrane transport carriers fuse with target membranes through engagement of cognate vSNAREs and tSNAREs on each membrane. How vSNAREs are sorted into transport carriers is incompletely understood. Here we show that VAMP7, the...
A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2.
Panagiota Vardaka, Teresa Lozano, Christopher Bot, Jonathan Ellery, Sarah K Whiteside, Charlotte J Imianowski, Stuart Farrow, Simon Walker, Hanneke Okkenhaug, Jie Yang, Klaus Okkenhaug, Paula Kuo, Rahul Roychoudhuri
Oct 15, 2020
Whereas effector CD4+ and CD8+ T cells promote immune activation and can drive clearance of infections and cancer, CD4+ regulatory T (Treg) cells suppress their function, contributing to both immune homeostasis and cancer...
The WDR11 complex facilitates the tethering of AP-1-derived vesicles.
Paloma Navarro Negredo, James R Edgar, Paul T Manna, Robin Antrobus, Margaret S Robinson
Jul 20, 2018
Vesicluar transport of proteins from endosomes to the trans-Golgi network (TGN) is an essential cellular pathway, but much of its machinery is still unknown. A screen for genes involved in endosome-to-TGN trafficking produced...
Adaptor Protein Complex 1 Autoantigens CRISPR-Cas Systems Cytoplasmic Vesicles Endosomes GTPase-Activating Proteins HEK293 Cells HeLa Cells Humans Membrane Proteins Microscopy Fluorescence Multiprotein Complexes Protein Binding Protein Transport Proto-Oncogene Proteins RNA Interference trans-Golgi Network
Connecting researchers at the University of Bath
Jez Cope and Geraldine Jones describe a recent series of events introducing social media to research students at the University of Bath.
A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2
Panagiota Vardaka, Teresa Lozano, Christopher Bot, Jonathan Ellery, Sarah K. Whiteside, Charlotte J. Imianowski, Stuart Farrow, Simon Walker, Hanneke Okkenhaug, Jie Yang, Klaus Okkenhaug, Paula Kuo, Rahul Roychoudhuri
Nov 03, 2020
Abstract: Whereas effector CD4+ and CD8+ T cells promote immune activation and can drive clearance of infections and cancer, CD4+ regulatory T (Treg) cells suppress their function, contributing to both immune homeostasis and...
Travelling lattice waves in a toy model of Lennard-Jones interaction
We consider an infinite lattice model, where particles interact with nearest neighbour (NN) and next-to-nearest neighbours (NNN); the NN and NNN springs act against each other to mimic the Lennard-Jones potential. The existence...
Travelling lattice waves in a toy model of Lennard-Jones interaction
We consider an infinite lattice model, where particles interact with nearest neighbour (NN) and next-to-nearest neighbours (NNN); the NN and NNN springs act against each other to mimic the Lennard-Jones potential. The existence...
Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting.
Paloma Navarro Negredo, James R Edgar, Antoni G Wrobel, Nathan R Zaccai, Robin Antrobus, David J Owen, Margaret S Robinson
Sep 11, 2018
Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. To find acidic cluster sorting machinery, we performed a gene-trap...
Adaptor Protein Complex 1 Adaptor Protein Complex mu Subunits CRISPR-Cas Systems Clathrin-Coated Vesicles Flow Cytometry Gene Knockdown Techniques Genotype HEK293 Cells HIV-1 HeLa Cells Histocompatibility Antigens Class I Host-Pathogen Interactions Humans Models Molecular Mutation Phenotype Protein Binding Protein Interaction Domains and Motifs Protein Transport Structure-Activity Relationship Time Factors Transfection nef Gene Products Human Immunodeficiency Virus
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