Begin your search of the AGOSR Open Access Database

Search

Results: 153
Cover Image for Neuroarthropathy in diabetes View Article
Neuroarthropathy in diabetes
SE Johnson-Lynn, AW McCaskie, AP Coll, AHN Robinson
Jun 15, 2018
Charcot neuroarthropathy is a rare but serious complication of diabetes, causing progressive destruction of the bones and joints of the foot leading to deformity, altered biomechanics and an increased risk of ulceration....
1103 Clinical Sciences Biomedical Clinical Medicine and Science Autoimmune Disease Neurosciences Genetics Peripheral neuropathy Diabetes Neurodegenerative Metabolic and endocrine 2.1 Biological and endogenous factors
Cover Image for Osseointegration of porous apatite-wollastonite and poly(lactic acid) composite structures created using 3D printing techniques. View Article
Osseointegration of porous apatite-wollastonite and poly(lactic acid) composite structures created using 3D printing techniques.
Ion Tcacencu, Natacha Rodrigues, Naif Alharbi, Matthew Benning, Sotiria Toumpaniari, Elena Mancuso, Martyn Marshall, Oana Bretcanu, Mark Birch, Andrew McCaskie, Kenneth Dalgarno
Sep 05, 2018
A novel apatite-wollastonite/poly(lactic acid) (AW/PLA) composite structure, which matches cortical and cancellous bone properties has been produced and evaluated in vitro and in vivo. The composites structure has been produced...
Animals Apatites Biocompatible Materials Calcium Compounds Cells Cultured Male Osseointegration Polyesters Porosity printing Three-Dimensional Rats Rats Sprague-Dawley Silicates
Cover Image for Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. View Article
Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements.
Wte Briggs, Blt Guevel, AW McCaskie, SM McDonnell
Aug 18, 2017
Introduction The weekend effect is a perceived difference in outcome between medical care provided at the weekend when compared to that of a weekday. Clearly multifactorial, this effect remains incompletely understood and...
Arthroplasty Elective Surgical Procedures Length of Stay Postoperative care Preoperative Care Aged Analysis of Variance Arthroplasty Replacement Hip Arthroplasty Replacement Knee Elective Surgical Procedures Female Humans Length of Stay Male Middle Aged Perioperative Care Time Factors
Cover Image for Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. View Article
Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis.
JW MacKay, SBL Low, TO Smith, AP Toms, AW McCaskie, FJ Gilbert
Feb 06, 2018
OBJECTIVE: To assess reliability and discriminative validity of cartilage compositional magnetic resonance imaging (MRI) in knee osteoarthritis (OA). DESIGN: The study was carried out per PRISMA recommendations. We searched...
Cartilage composition Cartilage mapping Knee osteoarthritis Magnetic Resonance Imaging Quantitative cartilage imaging Aged Cartilage Articular Case-Control Studies Female Humans Magnetic Resonance Imaging Male Middle Aged Osteoarthritis Knee Reference Values Reproducibility of Results Sensitivity and Specificity Severity of Illness Index
Cover Image for Novel bioglasses for bone tissue repair and regeneration View Article
Novel bioglasses for bone tissue repair and regeneration
E Mancuso, OA Bretcanu, M Marshall, MA Birch, AW McCaskie, KW Dalgarno
Sep 29, 2017
Glass design Sintering ability Ion release biocompatibility Bone Substitutes
Cover Image for The role of orthobiologics in hip preservation surgery. View Article
The role of orthobiologics in hip preservation surgery.
Zeiad Alshameeri, Andrew McCaskie
Sep 05, 2018
The potential regenerative role of different orthobiologics is becoming more recognized for the treatment of chronic and degenerative musculoskeletal conditions. Over the last few years there has been an increasing number of...
1103 Clinical Sciences Clinical Clinical Medicine and Science Osteoporosis Musculoskeletal
Cover Image for Studying the creep behaviour of strechable capacitive sensor with barium titanate silicone elastomer composite View Article
Studying the creep behaviour of strechable capacitive sensor with barium titanate silicone elastomer composite
Eshwar Reddy Cholleti, Jonathan Stringer, Piaras Kelly, Chris Bowen, Kean Aw
Mar 01, 2021

In this paper, the creep behaviour of stretchable interdigital capacitive (IDC) large strain sensors is studied. A generalized Kelvin-Voigt (GKV) model is used to study the creep behaviour of the sensor's substrate material...

barium titanate Creep Generalized kelvin-voigt (GKV) model Large strain sensor Silicone based elastomer (ecoflex) visco-hyper elastic
Cover Image for Studying the creep behaviour of strechable capacitive sensor with barium titanate silicone elastomer composite View Article
Studying the creep behaviour of strechable capacitive sensor with barium titanate silicone elastomer composite
Eshwar Reddy Cholleti, Jonathan Stringer, Piaras Kelly, Chris Bowen, Kean Aw
Mar 01, 2021

In this paper, the creep behaviour of stretchable interdigital capacitive (IDC) large strain sensors is studied. A generalized Kelvin-Voigt (GKV) model is used to study the creep behaviour of the sensor's substrate material...

barium titanate Creep Generalized kelvin-voigt (GKV) model Large strain sensor Silicone based elastomer (ecoflex) visco-hyper elastic
Cover Image for Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus View Article
Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus
S Hackinger, K Trajanoska, U Styrkarsdottir, E Zengini, J Steinberg, GRS Ritchie, K Hatzikotoulas, A Gilly, E Evangelou, JP Kemp, GEFOS Consortium arcOGEN Consortium, D Evans, T Ingvarsson, H Jonsson, U Thorsteinsdottir, K Stefansson, AW McCaskie, RA Brooks, JM Wilkinson, F Rivadeneira, E Zeggini
Nov 20, 2017
Phenotype Bone mineral density Bone Remodeling Cartilage exostoses neck of femur Genes Genome hip region Introns knee region Knee Joint lumbar vertebra Osteoarthritis single nucleotide polymorphism Genetics pleiotropism Causality smad3 gene datasets
Cover Image for Peripheral mononuclear blood cell apheresis in a preclinical ovine model. View Article
Peripheral mononuclear blood cell apheresis in a preclinical ovine model.
Helen Lydon, Roger Brooks, Andrew McCaskie, Frances Henson
Apr 12, 2018
Background. Recent research has demonstrated that circulating peripheral blood mononuclear fractions (PBMC) containing haematopoietic stem (HSC)/progenitor cells have the potential to play a crucial role in regenerative medicine...
Leukocytes Mononuclear Animals Sheep Granulocyte Colony-Stimulating Factor Leukocyte Count Leukapheresis Female
Cover Image for Translational arrest due to cytoplasmic redox stress delays adaptation to growth on methanol and heterologous protein expression in a typical fed-batch culture of <i>Pichia pastoris</i> View Article
Translational arrest due to cytoplasmic redox stress delays adaptation to growth on methanol and heterologous protein expression in a typical fed-batch culture of <i>Pichia pastoris</i>
Bryn Edwards-Jones, Rochelle Aw, Geraint R. Barton, Gregory D. Tredwell, Jacob G. Bundy, David J. Leak
Mar 18, 2015

Results: We have followed a typical fed-batch induction regime for heterologous protein production under the control of the AOX1 promoter using bothmicroarray and metabolomic analysis. The genetic constructs involved 1 and 3...

Cover Image for High water vs. ad libitum water intake for autosomal dominant polycystic kidney disease View Article
High water vs. ad libitum water intake for autosomal dominant polycystic kidney disease
R El-Damanawi, M Lee, T Harris, LB Cowley, S Bond, H Pavey, RN Sandford, IB Wilkinson, FE Karet Frankl, TF Hiemstra
Dec 02, 2020
BACKGROUND: Vasopressin stimulates cyst growth in autosomal dominant polycystic kidney disease (ADPKD) and is a key therapeutic target. Evaluation of high water intake as an alternative to pharmacological vasopressin blockade is...
Adult drinking Feasibility Studies Female Glomerular Filtration Rate Humans Male Middle Aged Polycystic Kidney Autosomal Dominant Prospective Studies Treatment Outcome Vasopressins water Young Adult
Cover Image for The effect of barium titanate ceramic loading on the stress relaxation behavior of barium titanate-silicone elastomer composites View Article
The effect of barium titanate ceramic loading on the stress relaxation behavior of barium titanate-silicone elastomer composites
Eshwar Reddy Cholleti, Jonathan Stringer, Piaras Kelly, Chris Bowen, Kean Aw
Dec 31, 2020

The stress relaxation behavior of barium titanate (BTO)-elastomer (Ecoflex) composites, as used in large strain sensors, is studied using the generalized Maxwell-Wiechert model. In this article, we examine the stress...

barium titanate ecoflex generalized Maxwell-Wiechert model stress relaxation visco-hyper elastic
Cover Image for Why does using personal strengths at work increase employee engagement; who makes the most out of it; and how? View Article
Why does using personal strengths at work increase employee engagement; who makes the most out of it; and how?
Remus Ilies, Yukun Liu, Sherry Aw, Mireia Las Heras, Yasin Rofcanin
Apr 01, 2024

Engaging in behaviors that take advantage of one's personal strengths at work can promote employee flourishing in the workplace and mental health. Personal strengths use has thus gained increasing attention within...

Cover Image for Poetics Contra Psychoanalysis View Article
Poetics Contra Psychoanalysis
AW Freer
May 18, 2017
This essay argues that psychoanalytic literary criticism has largely failed because it has assumed that literature and psychoanalysis share common analytical ground. I contend that psychoanalytic approaches necessarily deform...
psychoanalytic criticism psychoanalysis hermeneutics interpretation
Cover Image for Shelley’s Vestimentary Poetics View Article
Shelley’s Vestimentary Poetics
AW Freer
May 19, 2017
The figures of veils in Shelley’s poetics have long been understood as an inconsistent and potentially confused contribution to a debate between representational and expressive accounts of language. However, Shelley’s veils are...
Cover Image for The effect of barium titanate ceramic loading on the stress relaxation behavior of barium titanate-silicone elastomer composites View Article
The effect of barium titanate ceramic loading on the stress relaxation behavior of barium titanate-silicone elastomer composites
Eshwar Reddy Cholleti, Jonathan Stringer, Piaras Kelly, Chris Bowen, Kean Aw
Dec 31, 2020

The stress relaxation behavior of barium titanate (BTO)-elastomer (Ecoflex) composites, as used in large strain sensors, is studied using the generalized Maxwell-Wiechert model. In this article, we examine the stress...

barium titanate ecoflex generalized Maxwell-Wiechert model stress relaxation visco-hyper elastic
Cover Image for Using apheresis-derived cells to augment microdrilling in the treatment of chondral defects in an ovine model. View Article
Using apheresis-derived cells to augment microdrilling in the treatment of chondral defects in an ovine model.
Frances Henson, Helen Lydon, Mark Birch, Roger Brooks, Andrew McCaskie
Jan 12, 2021
The treatment of chondral defects using microdrilling often results in a mechanically weak fibrocartilagenous repair, rather than a more robust hyaline cartilage repair. Many different microfracture/microdrilling augmentation...
apheresis cartilage healing chondral defect Ovine Animals Arthroplasty Subchondral Blood Component Removal Female Granulocyte Colony-Stimulating Factor Peripheral Blood Stem Cell Transplantation Sheep Transplantation Autologous
Cover Image for Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships. View Article
Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships.
Ronald de Vlaming, Eric AW Slob, Patrick JF Groenen, Cornelius A Rietveld
Sep 02, 2022
GREML genetic correlation Genetic factor model Genomic SEM SNP heritability Genome Genome-Wide Association Study Genomics Humans Models Genetic Multifactorial Inheritance Phenotype Polymorphism Single Nucleotide
Cover Image for Why does using personal strengths at work increase employee engagement; who makes the most out of it; and how? View Article
Why does using personal strengths at work increase employee engagement; who makes the most out of it; and how?
Remus Ilies, Yukun Liu, Sherry Aw, Mireia Las Heras, Yasin Rofcanin
Apr 01, 2024

Engaging in behaviors that take advantage of one's personal strengths at work can promote employee flourishing in the workplace and mental health. Personal strengths use has thus gained increasing attention within...

Cover Image for On the transport of heavy particles through a downward displacement-ventilated space View Article
On the transport of heavy particles through a downward displacement-ventilated space
N Mingotti, AW Woods
Jun 01, 2015
convection in cavities drops and bubbles
Cover Image for Simulating open quantum dynamics with time-dependent variational matrix product states View Article
Simulating open quantum dynamics with time-dependent variational matrix product states
FAYN Schröder, AW Chin
Mar 04, 2016
Cover Image for Advances in osteoarthritis imaging View Article
Advances in osteoarthritis imaging
Stephen McDonnell, Tom Turmezei, Martin Graves, Andrew McCaskie, Joshua Kaggie
Oct 17, 2016
Cover Image for BedMachine v3 View Article
BedMachine v3
M Morlighem, CN Williams, E Rignot, L An, JE Arndt, JL Bamber, G Catania, N Chauché, JA Dowdeswell, B Dorschel, I Fenty, K Hogan, I Howat, A Hubbard, M Jakobsson, TM Jordan, KK Kjeldsen, R Millan, L Mayer, J Mouginot, BPY Noël, C O'Cofaigh, S Palmer, S Rysgaard, H Seroussi, MJ Siegert, P Slabon, F Straneo, MR van den Broeke, W Weinrebe, M Wood, KB Zinglersen
Jan 24, 2018
Greenland's bed topography is a primary control on ice flow, grounding line migration, calving dynamics, and subglacial drainage. Moreover, fjord bathymetry regulates the penetration of warm Atlantic water (AW) that rapidly...
Greenland bathymetry glaciology mass conservation multibeam echo sounding radar echo sounding
Cover Image for Translational arrest due to cytoplasmic redox stress delays adaptation to growth on methanol and heterologous protein expression in a typical fed-batch culture of <i>Pichia pastoris</i> View Article
Translational arrest due to cytoplasmic redox stress delays adaptation to growth on methanol and heterologous protein expression in a typical fed-batch culture of <i>Pichia pastoris</i>
Bryn Edwards-Jones, Rochelle Aw, Geraint R. Barton, Gregory D. Tredwell, Jacob G. Bundy, David J. Leak
Mar 18, 2015

Results: We have followed a typical fed-batch induction regime for heterologous protein production under the control of the AOX1 promoter using bothmicroarray and metabolomic analysis. The genetic constructs involved 1 and 3...

|<

<

1

2

3

4

5

>

>|