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Self-assembled lipoplexes of short interfering RNA (siRNA) using spermine-based fatty acid amide guanidines
Four guanidine derivatives of N4,N9-diacylated spermine have been designed, synthesized, and characterized. These guanidine-containing cationic lipids bound siRNA and formed nanoparticles. Two cationic lipids with C18...
Self-assembled lipoplexes of short interfering RNA (siRNA) using spermine-based fatty acid amide guanidines
Four guanidine derivatives of N4,N9-diacylated spermine have been designed, synthesized, and characterized. These guanidine-containing cationic lipids bound siRNA and formed nanoparticles. Two cationic lipids with C18...
Efficient gene silencing by self-assembled complexes of siRNA and symmetrical fatty acid amides of spermine
Gene silencing by siRNA (synthetic dsRNA of 21-25 nucleotides) is a well established biological tool in gene expression studies and has a promising therapeutic potential for difficult-to-treat diseases. Five fatty acids of...
Asymmetrical <em>N</em><sup>4</sup>,<em>N</em><sup>9</sup>-Diacyl Spermines
Our aim is to study the effects of varying the two acyl moieties in synthesized N4,N9-diacyl spermines on siRNA formulations and their delivery efficiency in cell lines. Six novel asymmetrical lipopolyamines...
Efficient gene silencing by self-assembled complexes of siRNA and symmetrical fatty acid amides of spermine
Gene silencing by siRNA (synthetic dsRNA of 21-25 nucleotides) is a well established biological tool in gene expression studies and has a promising therapeutic potential for difficult-to-treat diseases. Five fatty acids of...
Quantitative silencing of EGFP reporter gene by self-assembled siRNA lipoplexes of LinOS and cholesterol
Non-viral siRNA vectors prepared by the direct mixing of siRNA and mixtures of an asymmetric N4,N9-diacyl spermine conjugate, N4-linoleoyl-N9-oleoyl-1,12-diamino-4,9-diazadodecane (LinOS) with either cholesterol or DOPE, at...
Efficient silencing of EGFP reporter gene with siRNA delivered by asymmetrical <em>N</em><sup>4</sup>,<em>N</em><sup>9</sup>-diacyl spermines
It is important to obtain structure–activity relationship (SAR) data across cationic lipids for the self-assembly and nonviral intracellular delivery of siRNA. The aims of this work are to carry out a SAR study on the efficiency...
Asymmetrical <em>N</em><sup>4</sup>,<em>N</em><sup>9</sup>-Diacyl Spermines
Our aim is to study the effects of varying the two acyl moieties in synthesized N4,N9-diacyl spermines on siRNA formulations and their delivery efficiency in cell lines. Six novel asymmetrical lipopolyamines...
Efficient silencing of EGFP reporter gene with siRNA delivered by asymmetrical <em>N</em><sup>4</sup>,<em>N</em><sup>9</sup>-diacyl spermines
It is important to obtain structure–activity relationship (SAR) data across cationic lipids for the self-assembly and nonviral intracellular delivery of siRNA. The aims of this work are to carry out a SAR study on the efficiency...
Quantitative silencing of EGFP reporter gene by self-assembled siRNA lipoplexes of LinOS and cholesterol
Non-viral siRNA vectors prepared by the direct mixing of siRNA and mixtures of an asymmetric N4,N9-diacyl spermine conjugate, N4-linoleoyl-N9-oleoyl-1,12-diamino-4,9-diazadodecane (LinOS) with either cholesterol or DOPE, at...
The effect of conducting boundaries on Lapwood-Prats convection
We investigate the onset of convection in a uniform, constant-thickness, horizontal porous layer which is heated from below. The layer is bounded above and below by thermally conducting but impermeable layers. Our aim is to...
A Method Based on a New Word Embedding Approach for Process Model Matching
This paper proposes a method based on a new word embedding approach for matching business process model. The proposed method aligns two process models in four steps. First activity labels are extracted and pre-processed to...
Published by: IGI Global Scientific Publishing
The Influence of Bounding Plates on Species Separation in a Vertical Thermogravitational Column
Abdelkader Mojtabi, Pierre Costeseque, Bafétigué Ouattara, Marie Catherine Charrier-Mojtabi, D A S Rees
Mar 31, 2022
In this paper, an analytical and numerical analysis of the species separation in a binary mixture is performed. The main objective is to study the influence of the thickness and the nature of the bounding plates of the...
The effect of conducting boundaries on Lapwood-Prats convection
We investigate the onset of convection in a uniform, constant-thickness, horizontal porous layer which is heated from below. The layer is bounded above and below by thermally conducting but impermeable layers. Our aim is to...
The Influence of Bounding Plates on Species Separation in a Vertical Thermogravitational Column
Abdelkader Mojtabi, Pierre Costeseque, Bafétigué Ouattara, Marie Catherine Charrier-Mojtabi, D A S Rees
Mar 31, 2022
In this paper, an analytical and numerical analysis of the species separation in a binary mixture is performed. The main objective is to study the influence of the thickness and the nature of the bounding plates of the...
Dynamic Modelling and Performance Optimization-Based Sliding Mode Control of Process Drying in a Convective Tunnel Dryer
In this work, we thoroughly investigate the use of sliding mode control for nonlinear systems, specially its application for the control of dryer designed for drying food products. A dynamic model of the drying process has been...
Published by: IGI Global Scientific Publishing
State of the Art in Alcohol Sensing with 2D Materials
Highlights: A current review on the applications of graphene and other two-dimensional (2D) materials in alcohol detection. A thorough discussion on the fundamental principles and the advantages of using 2D materials in sensing...
The effect of conducting bounding horizontal plates on species separation in porous cavity saturated by a binary mixture
Abdelkader Mojtabi, Bafétigué Ouattara, D. Andrew S. Rees, Marie Catherine Charrier-Mojtabi
Nov 01, 2018
In this paper, an analytical and numerical study of species separation in binary mixtures taking account of the presence of bounding plates for the cell is presented. A rectangular horizontal porous cavity saturated by a...
convection porous medium Soret effect Species separation Stability Thermogravitational-diffusion /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/subjectarea/asjc/1500/1507 name=Fluid Flow and Transfer Processes
Lurk or De-Lurk?
Ali Abdelkader
Jan 01, 2022
Drawing on three theories; uses and gratification, social identity, and reasoned action, this study investigates the moderating role of type of participation and the sport fanaticism between brand community identification (BCI)...
Published by: IGI Global Scientific Publishing
State of the Art in Alcohol Sensing with 2D Materials
Highlights: A current review on the applications of graphene and other two-dimensional (2D) materials in alcohol detection. A thorough discussion on the fundamental principles and the advantages of using 2D materials in sensing...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
The effect of conducting bounding horizontal plates on species separation in porous cavity saturated by a binary mixture
Abdelkader Mojtabi, Bafétigué Ouattara, D. Andrew S. Rees, Marie Catherine Charrier-Mojtabi
Nov 01, 2018
In this paper, an analytical and numerical study of species separation in binary mixtures taking account of the presence of bounding plates for the cell is presented. A rectangular horizontal porous cavity saturated by a...
convection porous medium Soret effect Species separation Stability Thermogravitational-diffusion /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/subjectarea/asjc/1500/1507 name=Fluid Flow and Transfer Processes
State of the Art in Alcohol Sensing with 2D Materials.
Since the discovery of graphene, the star among new materials, there has been a surge of attention focused on the monatomic and monomolecular sheets which can be obtained by exfoliation of layered compounds. Such materials are...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect the patient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and if found...
Published by: IJHS Medical Association
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