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Results: 12
The epidemiology of dengue outbreaks in 2016 and 2017 in Ouagadougou, Burkina Faso.
Justin Im, Ruchita Balasubramanian, Moussa Ouedraogo, Lady Rosny Wandji Nana, Ondari D Mogeni, Hyon Jin Jeon, Tayma van Pomeren, Andrea Haselbeck, Jacqueline Kyungah Lim, Kristi Prifti, Stephen Baker, Christian G Meyer, Jerome H Kim, John D Clemens, Florian Marks, Abdramane Bassiahi Soura
Sep 21, 2020
BACKGROUND: Dengue is prevalent in as many as 128 countries with more than 100 million clinical episodes reported annually and four billion people estimated to be at risk. While dengue fever is systematically diagnosed in large...
The Burden of Typhoid Fever in Sub-Saharan Africa
Cara Lynn Kim, Ligia Maria Cruz Espinoza, Kirsten S Vannice, Birkneh Tilahun Tadesse, Ellis Owusu-Dabo, Raphaël Rakotozandrindrainy, Ilesh V Jani, Mekonnen Teferi, Abdramane Bassiahi Soura, Octavie Lunguya, A Duncan Steele, Florian Marks
Apr 20, 2022
While typhoid fever has largely been eliminated in high-income regions which have developed modern water, sanitation, and hygiene facilities, it remains a significant public health burden resulting in morbidity and mortality...
A Multicenter Cost-of-Illness and Long-term Socioeconomic Follow-up Study in the Severe Typhoid Fever in Africa Program
Enusa Ramani, Seeun Park, Trevor Toy, Ursula Panzner, Ondari D Mogeni, Justin Im, Ligia Maria Cruz Espinoza, Hyon Jin Jeon, Gi Deok Pak, Hyeongwon Seo, Yun Chon, Raphaël Rakotozandrindrainy, Ellis Owusu-Dabo, Isaac Osei, Abdramane Bassiahi Soura, Mekonnen Teferi, Florian Marks, Vittal Mogasale
Nov 26, 2019
BACKGROUND: There are limited data on typhoid fever cost of illness (COI) and economic impact from Africa. Health economic data are essential for measuring the cost-effectiveness of vaccination or other disease control...
Revisiting steroidogenesis and its role in immune regulation with the advanced tools and technologies.
Historically tools and technologies facilitated scientific discoveries. Steroid hormone research is not an exception. Unfortunately, the dramatic advancement of the field faded this research area and flagged it as a solved...
The HPAfrica protocol
Gi Deok Pak, Andrea Haekyung Haselbeck, Hyeong Won Seo, Isaac Osei, John Amuasi, Robert F Breiman, Ligia Maria Cruz Espinosa, Marianne Holm, Justin Im, Geun Hyeog Jang, Hyon Jin Jeon, Stephen P Luby, Octavie Lunguya-Metila, William MacWright, Ondari Daniel Mogeni, Iruka N Okeke, Ellis Owusu-Dabo, Jin Kyung Park, Se Eun Park, Oluwafemi Popoola, Hye Jin Seo, Abdramane Bassiahi Soura, Mekonnen Teferi, Trevor Toy, Yun Chon, Mathilde Rafindrakalia, Raphaël Rakotozandrindrainy, Christian G Meyer, Florian Marks, Ursula Panzner
Feb 19, 2019
INTRODUCTION: The objective of the Health Population Africa (HPAfrica) study is to determine health behaviour and population-based factors, including socioeconomic, ethnographic, hygiene and sanitation factors, at sites of the...
Sub-Saharan Africa health/hygiene behavior hpafrica Study population sampling frame/spatial sampling Sanitation socio-economic Africa South of the Sahara Cohort Studies Cross-Sectional Studies Geographic Information Systems Health Behavior Humans Hygiene Population Surveillance Research Design Sanitation Socioeconomic Factors Spatio-Temporal Analysis Typhoid Fever
Determining the Best Immunization Strategy for Protecting African Children Against Invasive Salmonella Disease.
Hyon Jin Jeon, Gi Deok Pak, Justin Im, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Amy Gassama Sow, Abdramane Bassiahi Soura, Nagla Gasmelseed, Karen H Keddy, Morten Bjerregaard-Andersen, Frank Konings, Abraham Aseffa, John A Crump, Yun Chon, Robert F Breiman, Se Eun Park, Ligia Maria Cruz Espinoza, Hye Jin Seo, Jürgen May, Christian G Meyer, Jason R Andrews, Ursula Panzner, Vera von Kalckreuth, Thomas F Wierzba, Raphaël Rakotozandrindrainy, Gordon Dougan, Myron M Levine, Joachim Hombach, Jerome H Kim, John D Clemens, Stephen Baker, Florian Marks
Sep 10, 2018
BACKGROUND: The World Health Organization recently prequalified a typhoid conjugate vaccine (TCV), recommending its use in persons ≥6 months to 45 years residing in typhoid fever (TF)-endemic areas. We now need to consider how...
The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries
Se Eun Park, Duy Thanh Pham, Gi Deok Pak, Ursula Panzner, Ligia Maria Cruz Espinoza, Vera von Kalckreuth, Justin Im, Ondari D. Mogeni, Heidi Schütt-Gerowitt, John A Crump, Robert F Breiman, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Raphaël Rakotozandrindrainy, Abdramane Bassiahi Soura, Abraham Aseffa, Nagla Gasmelseed, Arvinda Sooka, Karen H Keddy, Jürgen May, Peter Aaby, Holly M Biggs, Julian T Hertz, Joel M Montgomery, Leonard Cosmas, Beatrice Olack, Barry Fields, Nimako Sarpong, Tsiriniaina Jean Luco Razafindrabe, Tiana Mirana Raminosoa, Leon Parfait Kabore, Emmanuel Sampo, Mekonnen Teferi, Biruk Yeshitela, Muna Ahmed El Tayeb, Ralf Krumkamp, Denise Myriam Dekker, Anna Jaeger, Adama Tall, Amy Gassama, Aissatou Niang, Morten Bjerregaard-Andersen, Sandra Valborg Løfberg, Jessica Fung Deerin, Jin Kyung Park, Frank Konings, Megan E Carey, Sandra Van Puyvelde, Mohammad Ali, John Clemens, Gordon Dougan, Stephen Baker, Florian Marks
Aug 11, 2021
The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries.
Se Eun Park, Duy Thanh Pham, Gi Deok Pak, Ursula Panzner, Ligia Maria Cruz Espinoza, Vera von Kalckreuth, Justin Im, Ondari D Mogeni, Heidi Schütt-Gerowitt, John A Crump, Robert F Breiman, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Raphaël Rakotozandrindrainy, Abdramane Bassiahi Soura, Abraham Aseffa, Nagla Gasmelseed, Arvinda Sooka, Karen H Keddy, Jürgen May, Peter Aaby, Holly M Biggs, Julian T Hertz, Joel M Montgomery, Leonard Cosmas, Beatrice Olack, Barry Fields, Nimako Sarpong, Tsiriniaina Jean Luco Razafindrabe, Tiana Mirana Raminosoa, Leon Parfait Kabore, Emmanuel Sampo, Mekonnen Teferi, Biruk Yeshitela, Muna Ahmed El Tayeb, Ralf Krumkamp, Denise Myriam Dekker, Anna Jaeger, Adama Tall, Amy Gassama, Aissatou Niang, Morten Bjerregaard-Andersen, Sandra Valborg Løfberg, Jessica Fung Deerin, Jin Kyung Park, Frank Konings, Megan E Carey, Sandra Van Puyvelde, Mohammad Ali, John Clemens, Gordon Dougan, Stephen Baker, Florian Marks
Aug 09, 2021
BACKGROUND: Invasive non-typhoidal Salmonella (iNTS) is one of the leading causes of bacteraemia in sub-Saharan Africa. We aimed to provide a better understanding of the genetic characteristics and transmission patterns...
Multicountry Distribution and Characterization of Extended-spectrum β-Lactamase-associated Gram-negative Bacteria From Bloodstream Infections in Sub-Saharan Africa.
Trevor Toy, Gi Deok Pak, Trung Pham Duc, James I Campbell, Muna Ahmed El Tayeb, Vera von Kalckreuth, Justin Im, Ursula Panzner, Ligia Maria Cruz Espinoza, Daniel Eibach, Denise Myriam Dekker, Se Eun Park, Hyon Jin Jeon, Frank Konings, Ondari D Mogeni, Leonard Cosmas, Morten Bjerregaard-Andersen, Nagla Gasmelseed, Julian T Hertz, Anna Jaeger, Ralf Krumkamp, Benedikt Ley, Kamala Thriemer, Leon Parfait Kabore, Aissatou Niang, Tiana Mirana Raminosoa, Emmanuel Sampo, Nimako Sarpong, Abdramane Soura, Ellis Owusu-Dabo, Mekonnen Teferi, Biruk Yeshitela, Sven Poppert, Jürgen May, Jerome H Kim, Yun Chon, Jin Kyung Park, Abroaham Aseffa, Robert F Breiman, Heidi Schütt-Gerowitt, Peter Aaby, Yaw Adu-Sarkodie, John A Crump, Raphaël Rakotozandrindrainy, Christian G Meyer, Amy Gassama Sow, John D Clemens, Thomas F Wierzba, Stephen Baker, Florian Marks
Nov 26, 2019
BACKGROUND: Antimicrobial resistance (AMR) is a major global health concern, yet, there are noticeable gaps in AMR surveillance data in regions such as sub-Saharan Africa. We aimed to measure the prevalence of extended-spectrum...
Africa ESBL antibiotic resistance Antimicrobial resistance Extended-spectrum β-lactamase SURVEILLANCE Adolescent Adult Africa South of the Sahara Anti-Bacterial Agents Child Child Preschool Drug Resistance Multiple Bacterial Gram-Negative Bacteria Gram-Negative Bacterial Infections Humans Infant Infant Newborn Microbial Sensitivity Tests Middle Aged prevalence sentinel surveillance Young Adult beta-Lactamases
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa.
Se Eun Park, Duy Thanh Pham, Christine Boinett, Vanessa K Wong, Gi Deok Pak, Ursula Panzner, Ligia Maria Cruz Espinoza, Vera von Kalckreuth, Justin Im, Heidi Schütt-Gerowitt, John A Crump, Robert F Breiman, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Raphaël Rakotozandrindrainy, Abdramane Bassiahi Soura, Abraham Aseffa, Nagla Gasmelseed, Karen H Keddy, Jürgen May, Amy Gassama Sow, Peter Aaby, Holly M Biggs, Julian T Hertz, Joel M Montgomery, Leonard Cosmas, Beatrice Olack, Barry Fields, Nimako Sarpong, Tsiriniaina Jean Luco Razafindrabe, Tiana Mirana Raminosoa, Leon Parfait Kabore, Emmanuel Sampo, Mekonnen Teferi, Biruk Yeshitela, Muna Ahmed El Tayeb, Arvinda Sooka, Christian G Meyer, Ralf Krumkamp, Denise Myriam Dekker, Anna Jaeger, Sven Poppert, Adama Tall, Aissatou Niang, Morten Bjerregaard-Andersen, Sandra Valborg Løfberg, Hye Jin Seo, Hyon Jin Jeon, Jessica Fung Deerin, Jinkyung Park, Frank Konings, Mohammad Ali, John D Clemens, Peter Hughes, Juliet Nsimire Sendagala, Tobias Vudriko, Robert Downing, Usman N Ikumapayi, Grant A Mackenzie, Stephen Obaro, Silvia Argimon, David M Aanensen, Andrew Page, Jacqueline A Keane, Sebastian Duchene, Zoe Dyson, Kathryn E Holt, Gordon Dougan, Florian Marks, Stephen Baker
Feb 07, 2019
There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reconstruction of whole genome...
Incidence of invasive salmonella disease in sub-Saharan Africa
Florian Marks, Vera von Kalckreuth, Peter Aaby, Yaw Adu-Sarkodie, Muna Ahmed El Tayeb, Mohammad Ali, Abraham Aseffa, Stephen Baker, Holly M Biggs, Morten Bjerregaard-Andersen, Robert F Breiman, James I Campbell, Leonard Cosmas, John A Crump, Ligia Maria Cruz Espinoza, Jessica Fung Deerin, Denise Myriam Dekker, Barry S Fields, Nagla Gasmelseed, Julian T Hertz, Nguyen Van Minh Hoang, Justin Im, Anna Jaeger, Hyon Jin Jeon, Leon Parfait Kabore, Karen H Keddy, Frank Konings, Ralf Krumkamp, Benedikt Ley, Sandra Valborg Løfberg, Jürgen May, Christian G Meyer, Eric D Mintz, Joel M Montgomery, Aissatou Ahmet Niang, Chelsea Nichols, Beatrice Olack, Gi Deok Pak, Ursula Panzner, Jin Kyung Park, Se Eun Park, Henintsoa Rabezanahary, Raphaël Rakotozandrindrainy, Tiana Mirana Raminosoa, Tsiriniaina Jean Luco Razafindrabe, Emmanuel Sampo, Heidi Schütt-Gerowitt, Amy Gassama Sow, Nimako Sarpong, Hye Jin Seo, Arvinda Sooka, Abdramane Bassiahi Soura, Adama Tall, Mekonnen Teferi, Kamala Thriemer, Michelle R Warren, Biruk Yeshitela, John D Clemens, Thomas F Wierzba
Feb 19, 2019
BACKGROUND: Available incidence data for invasive salmonella disease in sub-Saharan Africa are scarce. Standardised, multicountry data are required to better understand the nature and burden of disease in Africa. We aimed to...