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Results: 34
Tianeptine
Background: Tianeptine is an atypical antidepressant marketed as Stablon since the late 1980’s. While chemically very similar to tricyclic antidepressants, tianeptine was thought to have the apparently paradoxical mechanism of...
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Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice
Opiates have been used historically for the treatment of depression. Renewed interest in the use of opiates as antidepressants has focused on the development of kappa opioid receptor (κ-receptor) antagonists. Buprenorphine acts...
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Tianeptine
Background: Tianeptine is an atypical antidepressant marketed as Stablon since the late 1980’s. While chemically very similar to tricyclic antidepressants, tianeptine was thought to have the apparently paradoxical mechanism of...
Published by:
Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice
Opiates have been used historically for the treatment of depression. Renewed interest in the use of opiates as antidepressants has focused on the development of kappa opioid receptor (κ-receptor) antagonists. Buprenorphine acts...
Published by:
Antidepressant-like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice

Background and Purpose: The κ receptor antagonists have potential for treating neuropsychiatric disorders. We have investigated the in vivo pharmacology of a novel buprenorphine analogue, BU10119, for the first time....

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Antidepressant-like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice

Background and Purpose: The κ receptor antagonists have potential for treating neuropsychiatric disorders. We have investigated the in vivo pharmacology of a novel buprenorphine analogue, BU10119, for the first time....

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Neural Differentiation of Incorrectly Predicted Memories.
Frequently experiencing an item in a specific context leads to the prediction that this item will occur when we encounter the same context in future. However, this prediction sometimes turns out to be incorrect, and recent...
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Empowering Girls' Higher Education Through Social Learning Platforms
This study explores the potential of social learning platforms (SLPs) to enhance female students' learning experiences in Saudi higher education and address socio-cultural constraints. It examines the advantages and...
Learning Analytics for Data-Driven Decision Making
This study examines the use of learning analytics to enhance instructional personalization and student engagement in online higher education. The research focuses on the engagement levels of students based on different access...
The Pupillary Light Reflex as a Biomarker of Concussion.
The size of our pupils changes continuously in response to variations in ambient light levels, a process known as the pupillary light reflex (PLR). The PLR is not a simple reflex as its function is modulated by cognitive brain...
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The Pupillary Light Reflex as a Biomarker of Concussion.
The size of our pupils changes continuously in response to variations in ambient light levels, a process known as the pupillary light reflex (PLR). The PLR is not a simple reflex as its function is modulated by cognitive brain...
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Building a Document-Oriented Warehouse Using NoSQL
The traditional data warehousing approaches should adapt to take into consideration novel needs and data structures. In this context, NoSQL technology is progressively gaining a place in the research and industry domains. This...
A Web-Based Assessment and Evaluation System for Architectural Design Studio Modules
Architectural design studio modules are known to be difficult to teach and/or assess. To acquire design skills, typically, students have several design modules during their program and several projects for each module. However...
Pregnant women's perceptions of physical activity
BACKGROUND: There are major health benefits of physical activity (PA) during pregnancy, yet there is scant data about a woman's knowledge and understanding of these benefits globally. DESIGN AND METHODS: We aimed to evaluate the...
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