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Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design
Indrani S. Bhattacharya, Joanne S. Haviland, Lesley Turner, Hilary Stobart, Ada Balasopoulou, Liba Stones, Anna M. Kirby, Cliona C. Kirwan, Charlotte E. Coles, Judith M. Bliss
Jun 14, 2021
Abstract: Background: For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty...
Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design.
Indrani S Bhattacharya, Joanne S Haviland, Lesley Turner, Hilary Stobart, Ada Balasopoulou, Liba Stones, Anna M Kirby, Cliona C Kirwan, Charlotte E Coles, Judith M Bliss
Jul 28, 2021
Background
For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty...
Cancer Breast cluster Radiotherapy oncology SWAT De-escalation stepped-wedge Decisional-conflict Humans Neoplasm Recurrence Local Chronic Disease Decision Making Decision Support Techniques Research Design Surveys and Questionnaires
Published by: Trials
Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design.
Indrani S Bhattacharya, Joanne S Haviland, Lesley Turner, Hilary Stobart, Ada Balasopoulou, Liba Stones, Anna M Kirby, Cliona C Kirwan, Charlotte E Coles, Judith M Bliss, PRIMETIME Trialists
Jul 12, 2021
BACKGROUND: For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty (decisional...
Stimulation of inositol 1,4,5-trisphosphate (IP<sub>3</sub>) receptor subtypes by Adenophostin A and its analogues
Inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular Ca2+ channels. Most animal cells express mixtures of the three IP3R subtypes encoded by vertebrate genomes. Adenophostin A (AdA) is the most potent naturally...
Stimulation of inositol 1,4,5-trisphosphate (IP<sub>3</sub>) receptor subtypes by Adenophostin A and its analogues
Inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular Ca2+ channels. Most animal cells express mixtures of the three IP3R subtypes encoded by vertebrate genomes. Adenophostin A (AdA) is the most potent naturally...
The hyperluminous X‐ray source population
We have recently published a catalog of 1843 candidate ultraluminous X‐ray sources (ULXs). This is the largest catalog of ULXs to date and was built by cross‐correlating recent serendipitous source catalogs from the XMM‐Newton...
Select Methods in Quantitative Chemical Analysis
Florence Ada Brooks
Jan 01, 0001
This 18 page thesis examines various methods of quantitative chemical analysis.
quantitative analysis gravimetric analysis volumetric analysis weight Salts precipitates Chemistry Physical Sciences and Mathematics
Published by: Ursinus College
The Role of Interests in STEM Pursuit and Academic Performance
A good fit between students' interests, academic major, and subsequent career is critical for occupational success and satisfaction. Substantial work has examined how individual differences in interests are linked with academic...
Published by: IGI Global Scientific Publishing
Buffering noise
KAT2A is a histone acetyltransferase recently identified as a vulnerability in at least some forms of Acute Myeloid Leukemia (AML). Its loss or inhibition prompts leukemia stem cells out of self-renewal and into differentiation...
Turning Clients into Superheroes through Accessibility Consulting
Robbie Kopp
Jan 01, 0001
Breaking Down the Physical and Digital Walls to Access from the Inside Out. Including people with disabilities in physical and online spaces is often overlooked in the scheme of social justice. The presenter will talk about...
Published by: Winthrop University
A Framework for Evaluating Information Transparency in Supply Chains
Private, public, profit, and non-profit organizations, and society as a whole currently face a significant reliable information necessity problem. Especially supply chains need trustworthy information to perform their activities...
Published by: IGI Global Scientific Publishing
Basketball Standout Dequesha McClanahan Joins Athletics Directors Scholar-Athlete Team
Winthrop University
Jan 01, 0001
McClanahan, who became the all-time scoring and assist leader in Big South Conference history and was just the second player in league history to be voted Big South Player of the Year for three consecutive seasons, has...
Published by: Winthrop University
Modelling upper respiratory viral load dynamics of SARS-CoV-2.
Joseph D Challenger, Cher Y Foo, Yue Wu, Ada WC Yan, Mahdi Moradi Marjaneh, Felicity Liew, Ryan S Thwaites, Lucy C Okell, Aubrey J Cunnington
Feb 13, 2022
Relationships between viral load, severity of illness, and transmissibility of virus are fundamental to understanding pathogenesis and devising better therapeutic and prevention strategies for COVID-19. Here we present...
Trends in undiagnosed HIV prevalence in England and implications for eliminating HIV transmission by 2030
Anne M Presanis, Ross J Harris, Peter D Kirwan, Ada Miltz, Sara Croxford, Ellen Heinsbroek, Christopher H Jackson, Hamish Mohammed, Alison E Brown, Valerie C Delpech, O Noel Gill, Daniela De Angelis
Oct 01, 2021
BACKGROUND: A target to eliminate HIV transmission in England by 2030 was set in early 2019. This study aimed to estimate trends from 2013 to 2019 in HIV prevalence, particularly the number of people living with undiagnosed HIV...
Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.
Joanna Rakoczy, Nisha Padmanabhan, Ada M Krzak, Jens Kieckbusch, Tereza Cindrova-Davies, Erica D Watson
Apr 18, 2018
INTRODUCTION: Throughout pregnancy, the placenta dynamically changes as trophoblast progenitors differentiate into mature trophoblast cell subtypes. This process is in part controlled by epigenetic regulation of DNA methylation...
Expression of the relaxin family peptide 4 receptor by enterochromaffin cells of the mouse large intestine.
Ada Koo, Ruslan V Pustovit, Orla RM Woodward, Jo E Lewis, Fiona M Gribble, Mohammed Akhter Hossain, Frank Reimann, John B Furness
Jun 15, 2022
Rapid evolution of coordinated and collective movement in response to artificial selection.
Alexander Kotrschal, Alexander Szorkovszky, James Herbert-Read, Natasha I Bloch, Maksym Romenskyy, Séverine Denise Buechel, Ada Fontrodona Eslava, Laura Sánchez Alòs, Hongli Zeng, Audrey Le Foll, Ganaël Braux, Kristiaan Pelckmans, Judith E Mank, David Sumpter, Niclas Kolm
Jan 11, 2021
Collective motion occurs when individuals use social interaction rules to respond to the movements and positions of their neighbors. How readily these social decisions are shaped by selection remains unknown. Through artificial...
Prevalence and phenotype of diabetes and prediabetes using fasting glucose vs HbA1c in a Caribbean population.
Nigel Unwin, Christina Howitt, Angela Mc Rose, T Alafia Samuels, Anselm Jm Hennis, Ian R Hambleton
Feb 21, 2018
BACKGROUND: Both fasting plasma glucose (FPG) and HbA1c are recommended for the diagnosis of diabetes and prediabetes by the American Diabetes Association (ADA), and for diabetes by the World Health Organization. The ADA...
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