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Factors Supporting Local Governments in Program Implementation Government and Business Entity Cooperation
Currently, there is a difference in the need for financing infrastructure development in Indonesia which cannot be provided by the APBN/APBD, nor capital expenditure by SOEs. Therefore, there is a gap between development needs...
Infrastructure Development Cooperation Between Government and Business Entities (PPP) Supporting Factors PPP scheme None
Published by: Indonesia Strategic Sustainability
Female Faces in Informal ‘Spaces’:
This paper critically examines how women employed in artisanal and small-scale mining (ASM)–low-tech mineral extraction and processing–in sub-Saharan Africa could be affected by moves made to formalize and support their...
Artisanal and small-scale mining (ASM) Informal sector Poverty Sub-Saharan Africa women /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation
Supply Chain Digitalization and Operational Performance
This study aims to analyze the effect of supply chain digitization on operational performance and new revenue streams. Data were collected from 123 companies or 492 observations. The samples are companies listed on the Indonesia...
Published by: IGI Global Scientific Publishing
The Grizzly, October 31, 2024
Beetlejuice Breakout: Grizzly Edition Spooky Scary STDs UC Theater Presents an Agatha Christie Double Bill! The Monsters are Due on Main Street Creating "Bullshit" Opinions: The Yap With Emily Veasey Nerf Club: A Merry...
Ursinus College Collegeville Pennsylvania newspaper escape rooms peer advocates Safe Sex Theater department Naila Twyman horror fiction Halloween costumes nerf club lacrosse team Trinity Reformed Church cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Female Faces in Informal ‘Spaces’:
This paper critically examines how women employed in artisanal and small-scale mining (ASM)–low-tech mineral extraction and processing–in sub-Saharan Africa could be affected by moves made to formalize and support their...
Artisanal and small-scale mining (ASM) Informal sector Poverty Sub-Saharan Africa women /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation
The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance
Andrea Coppa, Sanjib Guha, Stéphane Fourcade, Janani Parameswaran, Montserrat Ruiz, Ann B Moser, Agatha Schlüter, Michael P Murphy, Jose Miguel Lizcano, Antonio Miranda-Vizuete, Esther Dalfó, Aurora Pujol
Feb 18, 2020
Adrenoleukodystrophy is a neurometabolic disorder caused by a defective peroxisomal ABCD1 transporter of very long-chain fatty acids (VLCFAs). Its pathogenesis is incompletely understood. Here we characterize a nematode model of...
Axonal degeneration Hypodermis Lipid Droplets Mitochondria redox imbalance Peroxisomes X-linked adrenoleukodystrophy ATP Binding Cassette Transporter Subfamily D Member 1 ATP-Binding Cassette Transporters Adrenoleukodystrophy Animals Caenorhabditis elegans Fatty Acids Mice Mice Knockout Subcutaneous Tissue
Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with delayed gastric emptying.
Eleonora Seelig, Elana Henning, Julia M Keogh, Daniel Gillett, Evelyn Shin, John Buscombe, Agatha A van der Klaauw, I Sadaf Farooqi
Oct 25, 2021
OBJECTIVE: People who are severely obese due to melanocortin-4 receptor (MC4R) deficiency experience hyperphagia and impaired fullness after a meal (satiety). Meal-induced satiety is influenced by hormones, such as peptide-YY...
Divergent effects of central melanocortin signalling on fat and sucrose preference in humans.
Agatha A van der Klaauw, Julia M Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M Trowse, Naresh Subramanian, Stephen O'Rahilly, Paul C Fletcher, I Sadaf Farooqi
Oct 03, 2016
Obesity-associated melanocortin-4 receptor mutations are associated with changes in the brain response to food cues.
Agatha A van der Klaauw, Elisabeth AH von dem Hagen, Julia M Keogh, Elana Henning, Stephen O'Rahilly, Andrew D Lawrence, Andrew J Calder, I Sadaf Farooqi
Aug 19, 2014
Energy expenditure in frontotemporal dementia
Rebekah M Ahmed, Ramon Landin-Romero, Tinh-Hai Collet, Agatha A van der Klaauw, Emma Devenney, Elana Henning, Matthew C Kiernan, Olivier Piguet, I Sadaf Farooqi, John R Hodges
Oct 26, 2016
The Sleep/Wake Cycle is Directly Modulated by Changes in Energy Balance.
Tinh-Hai Collet, Agatha A van der Klaauw, Elana Henning, Julia M Keogh, Diane Suddaby, Sekesai V Dachi, Síle Dunbar, Sarah Kelway, Suzanne L Dickson, I Sadaf Farooqi, Sebastian M Schmid
Oct 07, 2016
Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people.
Joost Overduin, Tinh-Hai Collet, Nenad Medic, Elana Henning, Julia M Keogh, Faye Forsyth, Cheryl Stephenson, Marja W Kanning, Rianne MAJ Ruijschop, I Sadaf Farooqi, Agatha A van der Klaauw
Oct 28, 2016
Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.
Agatha A van der Klaauw, Sophie Croizier, Edson Mendes de Oliveira, Lukas KJ Stadler, Soyoung Park, Youxin Kong, Matthew C Banton, Panna Tandon, Audrey E Hendricks, Julia M Keogh, Susanna E Riley, Sofia Papadia, Elana Henning, Rebecca Bounds, Elena G Bochukova, Vanisha Mistry, Stephen O'Rahilly, Richard B Simerly, INTERVAL, UK10K consortium, James EN Minchin, Inês Barroso, E Yvonne Jones, Sebastien G Bouret, I Sadaf Farooqi
Jan 29, 2019
Hypothalamic melanocortin neurons play a pivotal role in weight regulation. Here, we examined the contribution of Semaphorin 3 (SEMA3) signaling to the development of these circuits. In genetic studies, we found 40 rare variants...
AGRP Neuropilins Plexins POMC Semaphorin 3s Hypothalamus obesity Adolescent Adult Animals Body Weight Cell Line Child Child Preschool Disease Models Animal Eating Energy Metabolism Female genetic variation Homeostasis Humans Hypothalamus Leptin Male Melanocortins Mice Mice Inbred C57BL Middle Aged Nerve Tissue Proteins Neurons obesity Receptors Cell Surface Semaphorins Young Adult Zebrafish
KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.
Laura R Pearce, Neli Atanassova, Matthew C Banton, Bill Bottomley, Agatha A van der Klaauw, Jean-Pierre Revelli, Audrey Hendricks, Julia M Keogh, Elana Henning, Deon Doree, Sabrina Jeter-Jones, Sumedha Garg, Elena G Bochukova, Rebecca Bounds, Sofie Ashford, Emma Gayton, Peter C Hindmarsh, Julian PH Shield, Elizabeth Crowne, David Barford, Nick J Wareham, UK10K consortium, Stephen O'Rahilly, Michael P Murphy, David R Powell, Ines Barroso, I Sadaf Farooqi
Mar 17, 2015
Age Factors Age of Onset Amino Acid Sequence Animals Child Energy Metabolism Fatty Acids Female Glucose Humans Hyperphagia Insulin Resistance MAP Kinase Signaling System Male Mice Models Molecular Molecular Sequence Data obesity Oxidation-Reduction Protein Serine-Threonine Kinases Protein Structure Tertiary Proto-Oncogene Proteins B-raf Sequence Alignment
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis.
Yongjie Yang, Agatha A van der Klaauw, Liangru Zhu, Tessa M Cacciottolo, Yanlin He, Lukas KJ Stadler, Chunmei Wang, Pingwen Xu, Kenji Saito, Antentor Hinton, Xiaofeng Yan, Julia M Keogh, Elana Henning, Matthew C Banton, Audrey E Hendricks, Elena G Bochukova, Vanisha Mistry, Katherine L Lawler, Lan Liao, Jianming Xu, Stephen O'Rahilly, Qingchun Tong, UK10K consortium, Inês Barroso, Bert W O'Malley, I Sadaf Farooqi, Yong Xu
Feb 01, 2019
Hypothalamic neurons expressing the anorectic peptide Pro-opiomelanocortin (Pomc) regulate food intake and body weight. Here, we show that Steroid Receptor Coactivator-1 (SRC-1) interacts with a target of leptin receptor...
Alleles Animals Body Weight Cell Line Tumor Crosses Genetic Gene Deletion Gene Knock-In Techniques genetic variation HEK293 Cells Heterozygote Homeostasis Humans Hypothalamus Leptin Male Membrane Potentials Mice Mice Transgenic Mutation Missense Neurons Nuclear Receptor Coactivator 1 obesity Phenotype
Clinical presentation and proteomic signature of patients with TANGO2 mutations.
Nadja Mingirulli, Angela Pyle, Denisa Hathazi, Charlotte L Alston, Nicolai Kohlschmidt, Gina O'Grady, Leigh Waddell, Frances Evesson, Sandra BT Cooper, Christian Turner, Jennifer Duff, Ana Topf, Delia Yubero, Cristina Jou, Andrés Nascimento, Carlos Ortez, Angels García-Cazorla, Claudia Gross, Maria O'Callaghan, Saikat Santra, Maryanne A Preece, Michael Champion, Sergei Korenev, Efsthatia Chronopoulou, Majumdar Anirban, Germaine Pierre, Daniel McArthur, Kyle Thompson, Placido Navas, Antonia Ribes, Frederic Tort, Agatha Schlüter, Aurora Pujol, Raquel Montero, Georgia Sarquella, Hanns Lochmüller, Cecilia Jiménez-Mallebrera, Robert W Taylor, Rafael Artuch, Janbernd Kirschner, Sarah C Grünert, Andreas Roos, Rita Horvath
Aug 02, 2019
Transport And Golgi Organization protein 2 (TANGO2) deficiency has recently been identified as a rare metabolic disorder with a distinct clinical and biochemical phenotype of recurrent metabolic crises, hypoglycemia, lactic...
TANGO2 fatty acid metabolism metabolic encephalomyopathy MITOCHONDRIAL DYSFUNCTION proteomic analysis rhabdomyolysis Brain Diseases Metabolic Fatty Acids Female Golgi Apparatus Homozygote Humans Infant Male Mitochondrial Diseases Muscle Weakness Mutation Oxidative Phosphorylation Phenotype Proteomics Rhabdomyolysis whole genome sequencing
Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST)
Alasdair PS Munro, Shuo Feng, Leila Janani, Victoria Cornelius, Parvinder K Aley, Gavin Babbage, David Baxter, Marcin Bula, Katrina Cathie, Krishna Chatterjee, Kate Dodd, Yvanne Enever, Ehsaan Qureshi, Anna L Goodman, Christopher A Green, Linda Harndahl, John Haughney, Alexander Hicks, Agatha A van der Klaauw, Nasir Kanji, Vincenzo Libri, Martin J Llewelyn, Alastair C McGregor, Mina Maallah, Angela M Minassian, Patrick Moore, Mehmood Mughal, Yama F Mujadidi, Kyra Holliday, Orod Osanlou, Rostam Osanlou, Daniel R Owens, Mihaela Pacurar, Adrian Palfreeman, Daniel Pan, Tommy Rampling, Karen Regan, Stephen Saich, Tanveer Bawa, Dinesh Saralaya, Sunil Sharma, Ray Sheridan, Emma C Thomson, Shirley Todd, Chris Twelves, Robert C Read, Sue Charlton, Bassam Hallis, Mary Ramsay, Nick Andrews, Teresa Lambe, Jonathan S Nguyen-Van-Tam, Matthew D Snape, Xinxue Liu, Saul N Faust, COV-BOOST study group
Jun 13, 2022
BACKGROUND: Some high-income countries have deployed fourth doses of COVID-19 vaccines, but the clinical need, effectiveness, timing, and dose of a fourth dose remain uncertain. We aimed to investigate the safety...
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK
Xinxue Liu, Alasdair PS Munro, Shuo Feng, Leila Janani, Parvinder K Aley, Gavin Babbage, David Baxter, Marcin Bula, Katrina Cathie, Krishna Chatterjee, Wanwisa Dejnirattisai, Kate Dodd, Yvanne Enever, Ehsaan Qureshi, Anna L Goodman, Christopher A Green, Linda Harndahl, John Haughney, Alexander Hicks, Agatha A van der Klaauw, Jonathan Kwok, Vincenzo Libri, Martin J Llewelyn, Alastair C McGregor, Angela M Minassian, Patrick Moore, Mehmood Mughal, Yama F Mujadidi, Kyra Holliday, Orod Osanlou, Rostam Osanlou, Daniel R Owens, Mihaela Pacurar, Adrian Palfreeman, Daniel Pan, Tommy Rampling, Karen Regan, Stephen Saich, Teona Serafimova, Dinesh Saralaya, Gavin R Screaton, Sunil Sharma, Ray Sheridan, Ann Sturdy, Piyada Supasa, Emma C Thomson, Shirley Todd, Chris Twelves, Robert C Read, Sue Charlton, Bassam Hallis, Mary Ramsay, Nick Andrews, Teresa Lambe, Jonathan S Nguyen-Van-Tam, Victoria Cornelius, Matthew D Snape, Saul N Faust, COV-BOOST study group
May 13, 2022
OBJECTIVES: To evaluate the persistence of immunogenicity three months after third dose boosters. METHODS: COV-BOOST is a multicentre, randomised, controlled, phase 2 trial of seven COVID-19 vaccines used as a third booster...
COVID-19 vaccine Fractional dose Heterologous boost Homologous boost Immunogenicity Persistence Third dose Ad26COVS1 Adult Aged Aged 80 and over Antibodies Viral BNT162 Vaccine covid-19 COVID-19 Vaccines ChAdOx1 nCoV-19 Humans Immunogenicity Vaccine Immunoglobulin G Middle Aged SARS-CoV-2 United Kingdom Viral Vaccines mRNA Vaccines
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Wilighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community
Oct 19, 2021
EMBO10 EMBO23 article ARTICLES computable knowledge repository large‐scale biocuration omics data analysis open access community effort systems biomedicine
Published by: Molecular Systems Biology
COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.
Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta-Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic-Milacic, Andrea Senff Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean-Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban-Medina, Maria Peña-Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Wilighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez-Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider
Nov 22, 2021
systems biomedicine omics data analysis computable knowledge repository Large-scale Biocuration open access community effort
Published by: Molecular Systems Biology
COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.
Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta-Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic-Milacic, Andrea Senff Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean-Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban-Medina, Maria Peña-Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Wilighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez-Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, COVID-19 Disease Map Community
Nov 22, 2021
We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here, we...
computable knowledge repository Large-scale Biocuration omics data analysis open access community effort systems biomedicine Antiviral Agents covid-19 Computational Biology Computer Graphics Cytokines Data Mining Databases Factual Gene Expression Regulation Host Microbial Interactions Humans Immunity Cellular Immunity Humoral Immunity Innate Lymphocytes Metabolic Networks and Pathways Myeloid Cells Protein Interaction Mapping SARS-CoV-2 Signal Transduction Software Transcription Factors Viral Proteins COVID-19 Drug Treatment