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Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation.
MF Michelle Sim, Elisa Persiani, Md Mesbah Uddin Talukder, George D Mcilroy, Ahlima Roumane, J Michael Edwardson, Justin J Rochford
Mar 02, 2020
Seipin deficiency causes severe congenital generalized lipodystrophy (CGL) and metabolic disease. However, how seipin regulates adipocyte development and function remains incompletely understood. We previously showed that seipin...
1-Acylglycerol-3-Phosphate O-Acyltransferase 3T3-L1 Cells Acyltransferases Adipocytes Adipogenesis Adipose Tissue Animals Cell Differentiation Diabetes mellitus Type 2 GTP-Binding Protein gamma Subunits Gene Expression Regulation HEK293 Cells Humans Lipid Metabolism Mice Mice Inbred C3H Microscopy Atomic Force Mutation
Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation
M. F. Michelle Sim, Elisa Persiani, Md. Mesbah Uddin Talukder, George D. Mcilroy, Ahlima Roumane, J. Michael Edwardson, Justin J. Rochford
Feb 23, 2021
Abstract: Seipin deficiency causes severe congenital generalized lipodystrophy (CGL) and metabolic disease. However, how seipin regulates adipocyte development and function remains incompletely understood. We previously showed...
Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation.
M F Michelle Sim, Elisa Persiani, Md Mesbah Uddin Talukder, George D Mcilroy, Ahlima Roumane, J Michael Edwardson, Justin J Rochford
Mar 27, 2020
Seipin deficiency causes severe congenital generalized lipodystrophy (CGL) and metabolic disease. However, how seipin regulates adipocyte development and function remains incompletely understood. We previously showed that seipin...
Published by: Scientific reports